The tobacco-specific carcinogen, 4-(methylnitrosamino)-1-(3-pyridyl)-1- butanone stimulates proliferation of immortalized human pancreatic duct epithelia through β-adrenergic transactivation of EGF receptors

Journal of Cancer Research and Clinical Oncology

Volumn 131, Issue 10, 2005, Pages 639-648

  Askari, Minoo D F ^a   Tsao, Ming Sound ^b   Schuller, Hildegard M ^a  

^a UNIVERSITY OF TENNESSEE   (United States)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

adrenergic receptors; EGFR; MAPK; NNK; Pancreatic cancer

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; 3 ISOPROPYLAMINO 1 (7 METHYL 4 INDANYLOXY) 2 BUTANOL; 4 (3 CHLOROANILINO) 6,7 DIMETHOXYQUINAZOLINE; 4 (METHYLNITROSAMINO) 1 (3 PYRIDYL) 1 BUTANONE; 9 (TETRAHYDRO 2 FURYL)ADENINE; ADENYLATE CYCLASE; BETA 1 ADRENERGIC RECEPTOR; BETA 1 ADRENERGIC RECEPTOR STIMULATING AGENT; BETA 2 ADRENERGIC RECEPTOR; BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; BETA ADRENERGIC RECEPTOR; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CARCINOGEN; CYCLIC AMP; ENZYME INHIBITOR; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR KINASE INHIBITOR; ISOPRENALINE; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE KINASE 2; PROPRANOLOL DERIVATIVE; TOBACCO SMOKE;

ARTICLE; BIOACCUMULATION; CARCINOGENESIS; CARCINOGENICITY; CELL IMMORTALIZATION; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; EPITHELIUM CELL; HUMAN; HUMAN CELL; PANCREAS CANCER; PANCREAS CARCINOMA; PANCREAS CELL; PANCREAS DUCT; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TOBACCO; WESTERN BLOTTING;

ADRENERGIC BETA-AGONISTS; BLOTTING, WESTERN; CARCINOGENS; CARCINOMA, PANCREATIC DUCTAL; CELL LINE, TRANSFORMED; CELL PROLIFERATION; CYCLIC AMP; EPITHELIUM; HUMANS; ISOPROTERENOL; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; NITROSAMINES; PANCREATIC DUCTS; PANCREATIC NEOPLASMS; PHOSPHORYLATION; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECEPTORS, ADRENERGIC, BETA-2; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TOBACCO; TRANS-ACTIVATION (GENETICS);

EID: 27144434360     PISSN: 01715216     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00432-005-0002-7     Document Type: Article

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