The nicotinic receptor antagonists abolish pathobiologic effects of tobacco-derived nitrosamines on BEP2D cells

Journal of Cancer Research and Clinical Oncology

Volumn 132, Issue 10, 2006, Pages 653-663

  Arredondo, Juan ^a   Chernyavsky, Alex I ^a   Grando, Sergei A ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

4 (Methylnitrosamino) 1 (3 pyridyl) 1 butanone; Apoptosis; BEP2D cells; GATA 3 activity; Gene expression; N Nitrosonornicotine; Nicotinic acetylcholine receptors

Indexed keywords

4 (METHYLNITROSAMINO) 1 (3 PYRIDYL) 1 BUTANONE; ALPHA BUNGAROTOXIN; ANTINEOPLASTIC AGENT; CYCLINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MECAMYLAMINE; NICOTINIC RECEPTOR; NICOTINIC RECEPTOR BLOCKING AGENT; NITROSAMINE; NITROSONORNICOTINE; PROTEIN BCL 2; RECEPTOR SUBUNIT; STAT1 PROTEIN; TRANSCRIPTION FACTOR GATA 3;

ARTICLE; BINDING AFFINITY; CANCER CELL; CANCER MODEL; CELL MEMBRANE; CELL PROLIFERATION; CHEMOPROPHYLAXIS; CONTROLLED STUDY; DRUG BINDING SITE; GENE EXPRESSION; GENOTOXICITY; HUMAN; HUMAN CELL; LUNG CANCER; LUNG CARCINOGENESIS; NUCLEOTIDE SEQUENCE; ONCOGENE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; RECEPTOR BLOCKING; SIGNAL TRANSDUCTION; TOBACCO; WESTERN BLOTTING;

ANTICARCINOGENIC AGENTS; BINDING SITES; BUNGAROTOXINS; CELL PROLIFERATION; CELLS, CULTURED; GATA3 TRANSCRIPTION FACTOR; HUMANS; LUNG; NF-KAPPA B; NICOTINIC ANTAGONISTS; NITROSAMINES; PROLIFERATING CELL NUCLEAR ANTIGEN; PROTEIN SUBUNITS; PROTO-ONCOGENE PROTEINS C-BCL-2; RECEPTORS, NICOTINIC; STAT1 TRANSCRIPTION FACTOR; TOBACCO; TRANSCRIPTION, GENETIC; UP-REGULATION;

EID: 33748184886     PISSN: 01715216     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00432-006-0113-9     Document Type: Article

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