Young and old genetically heterogeneous HET3 mice on a rapamycin diet are glucose intolerant but insulin sensitive

Aging Cell

Volumn 12, Issue 4, 2013, Pages 712-718

  Lamming, Dudley W ^a,b,c   Ye, Lan ^d   Astle, Clinton M ^e   Baur, Joseph A ^d   Sabatini, David M ^a,b,c   Harrison, David E ^e  

^a WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^c BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^d UNIVERSITY OF PENNSYLVANIA   (United States)

^e JACKSON LABORATORY   (United States)

Author keywords

Aging; Glucose tolerance; Heterogeneous mice; Insulin tolerance; Rapamycin

Indexed keywords

GLUCOSE; HEMOGLOBIN A1C; INSULIN; PYRUVIC ACID; RAPAMYCIN; GLUCOSE BLOOD LEVEL; GLYCOSYLATED HEMOGLOBIN;

AGED; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; FEMALE; GLUCOSE BLOOD LEVEL; GLUCOSE HOMEOSTASIS; GLUCOSE INTOLERANCE; GROUPS BY AGE; INSULIN RESISTANCE; INSULIN SENSITIVITY; INSULIN TOLERANCE TEST; LIFESPAN; LONGEVITY; MALE; MOUSE; MOUSE STRAIN; NONHUMAN; PRIORITY JOURNAL; AGE; ANIMAL; C57BL MOUSE; DIET; GENETIC HETEROGENEITY; GENOTYPE; METABOLISM; SPECIES DIFFERENCE;

ANIMALIA; MUS; RATTUS;

AGE FACTORS; ANIMALS; BLOOD GLUCOSE; DIET; FEMALE; GENETIC HETEROGENEITY; GENOTYPE; GLUCOSE; GLUCOSE INTOLERANCE; HEMOGLOBIN A, GLYCOSYLATED; INSULIN RESISTANCE; LONGEVITY; MALE; MICE; MICE, INBRED C57BL; PYRUVIC ACID; SIROLIMUS; SPECIES SPECIFICITY;

EID: 84880507764     PISSN: 14749718     EISSN: 14749726     Source Type: Journal    
DOI: 10.1111/acel.12097     Document Type: Article

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