-
1
-
-
84882281344
-
Obatoclax (GX15-070) triggers necroptosis by promoting the assembly of the necrosome on autophagosomal membranes
-
doi: 10.1038/cdd.2013.45
-
Basit F., Cristofanon S, Fulda S. 2013. Obatoclax (GX15-070) triggers necroptosis by promoting the assembly of the necrosome on autophagosomal membranes. Cell Death Differ doi: 10.1038/cdd.2013.45.
-
(2013)
Cell Death Differ
-
-
Basit, F.1
Cristofanon, S.2
Fulda, S.3
-
3
-
-
80755132824
-
The adaptor protein FADD protects epidermal keratinocytes from necroptosis in vivo and prevents skin inflammation
-
Bonnet M. C, Preukschat D, Welz PS, van Loo G, Ermolaeva MA, Bloch W., Haase I, Pasparakis M. 2011. The adaptor protein FADD protects epidermal keratinocytes from necroptosis in vivo and prevents skin inflammation. Immunity 35: 572-582.
-
(2011)
Immunity
, vol.35
, pp. 572-582
-
-
Bonnet, M.C.1
Preukschat, D.2
Welz, P.S.3
van Loo, G.4
Ermolaeva, M.A.5
Bloch, W.6
Haase, I.7
Pasparakis, M.8
-
4
-
-
84864389175
-
Autophagy suppresses RIP kinase-dependent necrosis enabling survival to mTOR inhibition
-
Bray K., Mathew R, Lau A, Kamphorst JJ, Fan J, Chen J, Chen HY, Ghavami A., Stein M, DiPaola RS, et al. 2012. Autophagy suppresses RIP kinase-dependent necrosis enabling survival to mTOR inhibition. PLoS ONE 7: e41831.
-
(2012)
PLoS ONE
, vol.7
-
-
Bray, K.1
Mathew, R.2
Lau, A.3
Kamphorst, J.J.4
Fan, J.5
Chen, J.6
Chen, H.Y.7
Ghavami, A.8
Stein, M.9
DiPaola, R.S.10
-
5
-
-
0016723594
-
An endotoxin-induced serum factor that causes necrosis of tumors
-
Carswell E. A, Old LJ, Kassel RL, Green S, Fiore N, Williamson B. 1975. An endotoxin-induced serum factor that causes necrosis of tumors. Proc Natl Acad Sci 72: 3666-3670.
-
(1975)
Proc Natl Acad Sci
, vol.72
, pp. 3666-3670
-
-
Carswell, E.A.1
Old, L.J.2
Kassel, R.L.3
Green, S.4
Fiore, N.5
Williamson, B.6
-
6
-
-
84868531636
-
Fueling the flames: Mammalian programmed necrosis in inflammatory diseases
-
Chan F.K. 2012. Fueling the flames: Mammalian programmed necrosis in inflammatory diseases. Cold Spring Harb Perspect Biol 4: a008805.
-
(2012)
Cold Spring Harb Perspect Biol
, vol.4
-
-
Chan, F.K.1
-
7
-
-
0347065342
-
A role for tumor necrosis factor receptor-2 and receptor-interacting protein in programmed necrosis and antiviral responses
-
Chan F. K, Shisler J, Bixby JG, Felices M, Zheng L, Appel M, Orenstein J., Moss B, Lenardo MJ. 2003. A role for tumor necrosis factor receptor-2 and receptor-interacting protein in programmed necrosis and antiviral responses. J Biol Chem 278: 51613-51621.
-
(2003)
J Biol Chem
, vol.278
, pp. 51613-51621
-
-
Chan, F.K.1
Shisler, J.2
Bixby, J.G.3
Felices, M.4
Zheng, L.5
Appel, M.6
Orenstein, J.7
Moss, B.8
Lenardo, M.J.9
-
8
-
-
79955484750
-
Mechanisms of necroptosis in T cells
-
Ch'en IL, Tsau JS, Molkentin JD, Komatsu M, Hedrick SM. 2011. Mechanisms of necroptosis in T cells. J Exp Med 208: 633-641.
-
(2011)
J Exp Med
, vol.208
, pp. 633-641
-
-
Ch'en, I.L.1
Tsau, J.S.2
Molkentin, J.D.3
Komatsu, M.4
Hedrick, S.M.5
-
9
-
-
84878755914
-
Diverse sequence determinants control human and mouse receptor interacting protein 3 (RIP3) and mixed lineage kinase domain-Like (MLKL) interaction in necroptotic signaling
-
Chen W., Zhou Z, Li L, Zhong CQ, Zheng X, Wu X, Zhang Y, Ma H., Huang D, Li W, et al. 2013. Diverse sequence determinants control human and mouse receptor interacting protein 3 (RIP3) and mixed lineage kinase domain-Like (MLKL) interaction in necroptotic signaling. J Biol Chem 288: 16247-16261.
-
(2013)
J Biol Chem
, vol.288
, pp. 16247-16261
-
-
Chen, W.1
Zhou, Z.2
Li, L.3
Zhong, C.Q.4
Zheng, X.5
Wu, X.6
Zhang, Y.7
Ma, H.8
Huang, D.9
Li, W.10
-
10
-
-
66449133280
-
Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virusinduced inflammation
-
Cho Y. S, Challa S, Moquin D, Genga R, Ray TD, Guildford M, Chan F.K. 2009. Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virusinduced inflammation. Cell 137: 1112-1123.
-
(2009)
Cell
, vol.137
, pp. 1112-1123
-
-
Cho, Y.S.1
Challa, S.2
Moquin, D.3
Genga, R.4
Ray, T.D.5
Guildford, M.6
Chan, F.K.7
-
11
-
-
30744452261
-
Inhibitor of apoptosis protein cIAP2 is essential for lipopolysaccharide-induced macrophage survival
-
Conte D., Holcik M, Lefebvre CA, Lacasse E, Picketts DJ, Wright KE, Korneluk RG. 2006. Inhibitor of apoptosis protein cIAP2 is essential for lipopolysaccharide-induced macrophage survival. Mol Cell Biol 26: 699-708.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 699-708
-
-
Conte, D.1
Holcik, M.2
Lefebvre, C.A.3
Lacasse, E.4
Picketts, D.J.5
Wright, K.E.6
Korneluk, R.G.7
-
12
-
-
16244377737
-
Posttranscriptional downregulation of c-IAP2 by the ubiquitin protein ligase c-IAP1 in vivo
-
Conze D. B, Albert L, Ferrick DA, Goeddel DV, Yeh WC, Mak T, Ashwell J.D. 2005. Posttranscriptional downregulation of c-IAP2 by the ubiquitin protein ligase c-IAP1 in vivo. Mol Cell Biol 25: 3348-3356.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 3348-3356
-
-
Conze, D.B.1
Albert, L.2
Ferrick, D.A.3
Goeddel, D.V.4
Yeh, W.C.5
Mak, T.6
Ashwell, J.D.7
-
13
-
-
67650638892
-
RIP kinases at the crossroads of cell death and survival
-
Declercq W., Vanden Berghe T, Vandenabeele P. 2009. RIP kinases at the crossroads of cell death and survival. Cell 138: 229-232.
-
(2009)
Cell
, vol.138
, pp. 229-232
-
-
Declercq, W.1
Vanden Berghe, T.2
Vandenabeele, P.3
-
14
-
-
33644840693
-
Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury
-
Degterev A., Huang Z, Boyce M, Li Y, Jagtap P, Mizushima N, Cuny G. D, Mitchison TJ, Moskowitz MA, Yuan J. 2005. Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury. Nat Chem Biol 1: 112-119.
-
(2005)
Nat Chem Biol
, vol.1
, pp. 112-119
-
-
Degterev, A.1
Huang, Z.2
Boyce, M.3
Li, Y.4
Jagtap, P.5
Mizushima, N.6
Cuny, G.D.7
Mitchison, T.J.8
Moskowitz, M.A.9
Yuan, J.10
-
15
-
-
42249102086
-
Identification of RIP1 kinase as a specific cellular target of necrostatins
-
Degterev A., Hitomi J, Germscheid M, Ch'en IL, Korkina O, Teng X., Abbott D, Cuny GD, Yuan C, Wagner G, et al. 2008. Identification of RIP1 kinase as a specific cellular target of necrostatins. Nat Chem Biol 4: 313-321.
-
(2008)
Nat Chem Biol
, vol.4
, pp. 313-321
-
-
Degterev, A.1
Hitomi, J.2
Germscheid, M.3
Ch'en, I.L.4
Korkina, O.5
Teng, X.6
Abbott, D.7
Cuny, G.D.8
Yuan, C.9
Wagner, G.10
-
16
-
-
84861712290
-
Survival function of the FADD-CASPASE-8-cFLIP(L) complex
-
Dillon C. P, Oberst A, Weinlich R, Janke LJ, Kang TB, Ben-Moshe T, Mak TW, Wallach D, Green DR. 2012. Survival function of the FADD-CASPASE-8-cFLIP(L) complex. Cell Rep 1: 401-407.
-
(2012)
Cell Rep
, vol.1
, pp. 401-407
-
-
Dillon, C.P.1
Oberst, A.2
Weinlich, R.3
Janke, L.J.4
Kang, T.B.5
Ben-Moshe, T.6
Mak, T.W.7
Wallach, D.8
Green, D.R.9
-
17
-
-
84255162797
-
RIP kinase-dependent necrosis drives lethal systemic inflammatory response syndrome
-
Duprez L., Takahashi N, Van Hauwermeiren F, Vandendriessche B, Goossens V, Vanden Berghe T, Declercq W, Libert C, Cauwels A., Vandenabeele P. 2011. RIP kinase-dependent necrosis drives lethal systemic inflammatory response syndrome. Immunity 35: 908-918.
-
(2011)
Immunity
, vol.35
, pp. 908-918
-
-
Duprez, L.1
Takahashi, N.2
van Hauwermeiren, F.3
Vandendriessche, B.4
Goossens, V.5
Vanden Berghe, T.6
Declercq, W.7
Libert, C.8
Cauwels, A.9
Vandenabeele, P.10
-
18
-
-
0022497852
-
Genetic control of programmed cell death in the nematode C elegans
-
Ellis H. M, Horvitz HR. 1986. Genetic control of programmed cell death in the nematode C. elegans. Cell 44: 817-829.
-
(1986)
Cell
, vol.44
, pp. 817-829
-
-
Ellis, H.M.1
Horvitz, H.R.2
-
19
-
-
34548437549
-
Cleavage of RIP3 inactivates its caspaseindependent apoptosis pathway by removal of kinase domain
-
Feng S., Yang Y, Mei Y, Ma L, Zhu DE, Hoti N, Castanares M, Wu M. 2007. Cleavage of RIP3 inactivates its caspaseindependent apoptosis pathway by removal of kinase domain. Cell Signal 19: 2056-2067.
-
(2007)
Cell Signal
, vol.19
, pp. 2056-2067
-
-
Feng, S.1
Yang, Y.2
Mei, Y.3
Ma, L.4
Zhu, D.E.5
Hoti, N.6
Castanares, M.7
Wu, M.8
-
20
-
-
41949127121
-
Anthrax lethal toxin and Salmonella elicit the common cell death pathway of caspase-1-dependent pyroptosis via distinct mechanisms
-
Fink S. L, Bergsbaken T, Cookson BT. 2008. Anthrax lethal toxin and Salmonella elicit the common cell death pathway of caspase-1-dependent pyroptosis via distinct mechanisms. Proc Natl Acad Sci 105: 4312-4317.
-
(2008)
Proc Natl Acad Sci
, vol.105
, pp. 4312-4317
-
-
Fink, S.L.1
Bergsbaken, T.2
Cookson, B.T.3
-
21
-
-
84877948815
-
Human ALKBH7 is required for alkylation and oxidation-induced programmed necrosis
-
Fu D., Jordan JJ, Samson LD. 2013. Human ALKBH7 is required for alkylation and oxidation-induced programmed necrosis. Genes Dev 27: 1089-1100.
-
(2013)
Genes Dev
, vol.27
, pp. 1089-1100
-
-
Fu, D.1
Jordan, J.J.2
Samson, L.D.3
-
22
-
-
79953240109
-
Linear ubiquitination prevents inflammation and regulates immune signalling
-
Gerlach B., Cordier SM, Schmukle AC, Emmerich CH, Rieser E, Haas T. L, Webb AI, Rickard JA, Anderton H, Wong WW, et al. 2011. Linear ubiquitination prevents inflammation and regulates immune signalling. Nature 471: 591-596.
-
(2011)
Nature
, vol.471
, pp. 591-596
-
-
Gerlach, B.1
Cordier, S.M.2
Schmukle, A.C.3
Emmerich, C.H.4
Rieser, E.5
Haas, T.L.6
Webb, A.I.7
Rickard, J.A.8
Anderton, H.9
Wong, W.W.10
-
23
-
-
80052845560
-
Caspase-8 regulates TNF-a-induced epithelial necroptosis and terminal ileitis
-
Gunther C., Martini E, Wittkopf N, Amann K, Weigmann B, Neumann H., Waldner MJ, Hedrick SM, Tenzer S, Neurath MF, et al. 2011. Caspase-8 regulates TNF-a-induced epithelial necroptosis and terminal ileitis. Nature 477: 335-339.
-
(2011)
Nature
, vol.477
, pp. 335-339
-
-
Gunther, C.1
Martini, E.2
Wittkopf, N.3
Amann, K.4
Weigmann, B.5
Neumann, H.6
Waldner, M.J.7
Hedrick, S.M.8
Tenzer, S.9
Neurath, M.F.10
-
24
-
-
79952284127
-
Hallmarks of cancer: The next generation
-
Hanahan D., Weinberg RA. 2011. Hallmarks of cancer: The next generation. Cell 144: 646-674.
-
(2011)
Cell
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
25
-
-
0035037802
-
Characterization of XIAP-deficient mice
-
Harlin H., Reffey SB, Duckett CS, Lindsten T, Thompson CB. 2001. Characterization of XIAP-deficient mice. Mol Cell Biol 21: 3604-3608.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 3604-3608
-
-
Harlin, H.1
Reffey, S.B.2
Duckett, C.S.3
Lindsten, T.4
Thompson, C.B.5
-
26
-
-
84879078861
-
Hepatocyte caspase-8 is an essential modulator of steatohepatitis in mice
-
Hatting M., Zhao G, Schumacher F, Sellge G, Masaoudi MA, Gabetaler N., Boekschoten M, Muller M, Liedtke C, Cubero F. J, et al. 2013. Hepatocyte caspase-8 is an essential modulator of steatohepatitis in mice. Hepatology 57: 2189-2201.
-
(2013)
Hepatology
, vol.57
, pp. 2189-2201
-
-
Hatting, M.1
Zhao, G.2
Schumacher, F.3
Sellge, G.4
Masaoudi, M.A.5
Gabetaler, N.6
Boekschoten, M.7
Muller, M.8
Liedtke, C.9
Cubero, F.J.10
-
27
-
-
66749183275
-
Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-a
-
He S., Wang L, Miao L, Wang T, Du F, Zhao L, Wang X. 2009. Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-a. Cell 137: 1100-1111.
-
(2009)
Cell
, vol.137
, pp. 1100-1111
-
-
He, S.1
Wang, L.2
Miao, L.3
Wang, T.4
Du, F.5
Zhao, L.6
Wang, X.7
-
28
-
-
84055181328
-
Toll-like receptors activate programmed necrosis in macrophages through a receptorinteracting kinase-3-mediated pathway
-
He S., Liang Y, Shao F, Wang X. 2011. Toll-like receptors activate programmed necrosis in macrophages through a receptorinteracting kinase-3-mediated pathway. Proc Natl Acad Sci 108: 20054-20059.
-
(2011)
Proc Natl Acad Sci
, vol.108
, pp. 20054-20059
-
-
He, S.1
Liang, Y.2
Shao, F.3
Wang, X.4
-
29
-
-
57649181391
-
Identification of a molecular signaling network that regulates a cellular necrotic cell death pathway
-
Hitomi J., Christofferson DE, Ng A, Yao J, Degterev A, Xavier RJ, Yuan J. 2008. Identification of a molecular signaling network that regulates a cellular necrotic cell death pathway. Cell 135: 1311-1323.
-
(2008)
Cell
, vol.135
, pp. 1311-1323
-
-
Hitomi, J.1
Christofferson, D.E.2
Ng, A.3
Yao, J.4
Degterev, A.5
Xavier, R.J.6
Yuan, J.7
-
30
-
-
5944233768
-
Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule
-
Holler N., Zaru R, Micheau O, Thome M, Attinger A, Valitutti S, Bodmer J. L, Schneider P, Seed B, Tschopp J. 2000. Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule. Nat Immunol 1: 489-495.
-
(2000)
Nat Immunol
, vol.1
, pp. 489-495
-
-
Holler, N.1
Zaru, R.2
Micheau, O.3
Thome, M.4
Attinger, A.5
Valitutti, S.6
Bodmer, J.L.7
Schneider, P.8
Seed, B.9
Tschopp, J.10
-
31
-
-
17144413785
-
Apoptosis induced by the tolllike receptor adaptor TRIF is dependent on its receptor interacting protein homotypic interaction motif
-
Kaiser W. J, Offermann MK. 2005. Apoptosis induced by the tolllike receptor adaptor TRIF is dependent on its receptor interacting protein homotypic interaction motif. J Immunol 174: 4942-4952.
-
(2005)
J Immunol
, vol.174
, pp. 4942-4952
-
-
Kaiser, W.J.1
Offermann, M.K.2
-
32
-
-
58749100879
-
Receptor-interacting protein homotypic interaction motif-dependent control of NF-kB activation via the DNA-dependent activator of IFN regulatory factors
-
Kaiser W. J, Upton JW, Mocarski ES. 2008. Receptor-interacting protein homotypic interaction motif-dependent control of NF-kB activation via the DNA-dependent activator of IFN regulatory factors. J Immunol 181: 6427-6434.
-
(2008)
J Immunol
, vol.181
, pp. 6427-6434
-
-
Kaiser, W.J.1
Upton, J.W.2
Mocarski, E.S.3
-
33
-
-
79952811804
-
RIP3 mediates the embryonic lethality of caspase-8-deficient mice
-
Kaiser W. J, Upton JW, Long AB, Livingston-Rosanoff D, Daley-Bauer L. P, Hakem R, Caspary T, Mocarski ES. 2011. RIP3 mediates the embryonic lethality of caspase-8-deficient mice. Nature 471: 368-372.
-
(2011)
Nature
, vol.471
, pp. 368-372
-
-
Kaiser, W.J.1
Upton, J.W.2
Long, A.B.3
Livingston-Rosanoff, D.4
Daley-Bauer, L.P.5
Hakem, R.6
Caspary, T.7
Mocarski, E.S.8
-
34
-
-
4344560197
-
Caspase-8 serves both apoptotic and nonapoptotic roles
-
Kang T. B, Ben-Moshe T, Varfolomeev EE, Pewzner-Jung Y, Yogev N, Jurewicz A, Waisman A, Brenner O, Haffner R, Gustafsson E, et al. 2004. Caspase-8 serves both apoptotic and nonapoptotic roles. J Immunol 173: 2976-2984.
-
(2004)
J Immunol
, vol.173
, pp. 2976-2984
-
-
Kang, T.B.1
Ben-Moshe, T.2
Varfolomeev, E.E.3
Pewzner-Jung, Y.4
Yogev, N.5
Jurewicz, A.6
Waisman, A.7
Brenner, O.8
Haffner, R.9
Gustafsson, E.10
-
35
-
-
84872764927
-
Caspase-8 blocks kinase RIPK3-mediated activation of the NLRP3 inflammasome
-
Kang T. B, Yang SH, Toth B, Kovalenko A, Wallach D. 2013. Caspase-8 blocks kinase RIPK3-mediated activation of the NLRP3 inflammasome. Immunity 38: 27-40.
-
(2013)
Immunity
, vol.38
, pp. 27-40
-
-
Kang, T.B.1
Yang, S.H.2
Toth, B.3
Kovalenko, A.4
Wallach, D.5
-
36
-
-
0034685982
-
The RIP-like kinase, RIP3, induces apoptosis and NF-kB nuclear translocation and localizes to mitochondria
-
Kasof G. M, Prosser JC, Liu D, Lorenzi MV, Gomes BC. 2000. The RIP-like kinase, RIP3, induces apoptosis and NF-kB nuclear translocation and localizes to mitochondria. FEBS Lett 473: 285-291.
-
(2000)
FEBS Lett
, vol.473
, pp. 285-291
-
-
Kasof, G.M.1
Prosser, J.C.2
Liu, D.3
Lorenzi, M.V.4
Gomes, B.C.5
-
37
-
-
0032033132
-
The death domain kinase RIP mediates the TNF-induced NF-kB signal
-
Kelliher M. A, Grimm S, Ishida Y, Kuo F, Stanger BZ, Leder P. 1998. The death domain kinase RIP mediates the TNF-induced NF-kB signal. Immunity 8: 297-303.
-
(1998)
Immunity
, vol.8
, pp. 297-303
-
-
Kelliher, M.A.1
Grimm, S.2
Ishida, Y.3
Kuo, F.4
Stanger, B.Z.5
Leder, P.6
-
38
-
-
0015383455
-
Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics
-
Kerr J. F, Wyllie AH, Currie AR. 1972. Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics. Br J Cancer 26: 239-257.
-
(1972)
Br J Cancer
, vol.26
, pp. 239-257
-
-
Kerr, J.F.1
Wyllie, A.H.2
Currie, A.R.3
-
39
-
-
70350484946
-
Caspase-8 deficiency in epidermal keratinocytes triggers an inflammatory skin disease
-
Kovalenko A., Kim JC, Kang TB, Rajput A, Bogdanov K, Dittrich-Breiholz O., Kracht M, Brenner O, Wallach D. 2009. Caspase-8 deficiency in epidermal keratinocytes triggers an inflammatory skin disease. J Exp Med 206: 2161-2177.
-
(2009)
J Exp Med
, vol.206
, pp. 2161-2177
-
-
Kovalenko, A.1
Kim, J.C.2
Kang, T.B.3
Rajput, A.4
Bogdanov, K.5
Dittrich-Breiholz, O.6
Kracht, M.7
Brenner, O.8
Wallach, D.9
-
40
-
-
0023697978
-
Tumor necrosis factor can induce both apoptic and necrotic forms of cell lysis
-
Laster S. M, Wood JG, Gooding LR. 1988. Tumor necrosis factor can induce both apoptic and necrotic forms of cell lysis. J Immunol 141: 2629-2634.
-
(1988)
J Immunol
, vol.141
, pp. 2629-2634
-
-
Laster, S.M.1
Wood, J.G.2
Gooding, L.R.3
-
41
-
-
84864240409
-
The RIP1/RIP3 necrosome forms a functional amyloid signaling complex required for programmed necrosis
-
Li J., McQuade T, Siemer AB, Napetschnig J, Moriwaki K, Hsiao YS, Damko E, Moquin D, Walz T, McDermott A, et al. 2012. The RIP1/RIP3 necrosome forms a functional amyloid signaling complex required for programmed necrosis. Cell 150: 339-350.
-
(2012)
Cell
, vol.150
, pp. 339-350
-
-
Li, J.1
McQuade, T.2
Siemer, A.B.3
Napetschnig, J.4
Moriwaki, K.5
Hsiao, Y.S.6
Damko, E.7
Moquin, D.8
Walz, T.9
McDermott, A.10
-
42
-
-
81855183262
-
Loss of caspase-8 protects mice against inflammation-related hepatocarcinogenesis but induces nonapoptotic liver injury
-
Liedtke C., Bangen JM, Freimuth J, Beraza N, Lambertz D, Cubero F. J, Hatting M, Karlmark KR, Streetz KL, Krombach GA, et al. 2011. Loss of caspase-8 protects mice against inflammation-related hepatocarcinogenesis but induces nonapoptotic liver injury. Gastroenterology 141: 2176-2187.
-
(2011)
Gastroenterology
, vol.141
, pp. 2176-2187
-
-
Liedtke, C.1
Bangen, J.M.2
Freimuth, J.3
Beraza, N.4
Lambertz, D.5
Cubero, F.J.6
Hatting, M.7
Karlmark, K.R.8
Streetz, K.L.9
Krombach, G.A.10
-
43
-
-
0033214236
-
Cleavage of the death domain kinase RIP by caspase-8 prompts TNF-induced apoptosis
-
Lin Y., Devin A, Rodriguez Y, Liu ZG. 1999. Cleavage of the death domain kinase RIP by caspase-8 prompts TNF-induced apoptosis. Genes Dev 13: 2514-2526.
-
(1999)
Genes Dev
, vol.13
, pp. 2514-2526
-
-
Lin, Y.1
Devin, A.2
Rodriguez, Y.3
Liu, Z.G.4
-
44
-
-
84873152891
-
A role of RIP3-mediated macrophage necrosis in atherosclerosis development
-
Lin J., Li H, Yang M, Ren J, Huang Z, Han F, Huang J, Ma J, Zhang D, Zhang Z, et al. 2013. A role of RIP3-mediated macrophage necrosis in atherosclerosis development. Cell Rep 3: 200-210.
-
(2013)
Cell Rep
, vol.3
, pp. 200-210
-
-
Lin, J.1
Li, H.2
Yang, M.3
Ren, J.4
Huang, Z.5
Han, F.6
Huang, J.7
Ma, J.8
Zhang, D.9
Zhang, Z.10
-
45
-
-
84862175306
-
Dichotomy between RIP1-and RIP3-mediated necroptosis in tumor necrosis factor-a-induced shock
-
Linkermann A., Brasen JH, De Zen F, Weinlich R, Schwendener RA, Green DR, Kunzendorf U, Krautwald S. 2012. Dichotomy between RIP1-and RIP3-mediated necroptosis in tumor necrosis factor-a-induced shock. Mol Med 18: 577-586.
-
(2012)
Mol Med
, vol.18
, pp. 577-586
-
-
Linkermann, A.1
Brasen, J.H.2
de Zen, F.3
Weinlich, R.4
Schwendener, R.A.5
Green, D.R.6
Kunzendorf, U.7
Krautwald, S.8
-
46
-
-
0000031083
-
Programmed cell death. II. Endocrine potentiation of the breakdown of the intersegmental mucles of silmoths
-
Lockshin R. A, Williams CM. 1964. Programmed cell death. II. Endocrine potentiation of the breakdown of the intersegmental mucles of silmoths. J Insect Physiol 10: 643-649.
-
(1964)
J Insect Physiol
, vol.10
, pp. 643-649
-
-
Lockshin, R.A.1
Williams, C.M.2
-
47
-
-
80053087284
-
Complementary roles of Fas-associated death domain (FADD) and receptor interacting protein kinase-3 (RIPK3) in T-cell homeostasis and antiviral immunity
-
Lu J. V, Weist BM, van Raam BJ, Marro BS, Nguyen LV, Srinivas P, Bell B. D, Luhrs KA, Lane TE, Salvesen GS, et al. 2011. Complementary roles of Fas-associated death domain (FADD) and receptor interacting protein kinase-3 (RIPK3) in T-cell homeostasis and antiviral immunity. Proc Natl Acad Sci 108: 15312-15317.
-
(2011)
Proc Natl Acad Sci
, vol.108
, pp. 15312-15317
-
-
Lu, J.V.1
Weist, B.M.2
van Raam, B.J.3
Marro, B.S.4
Nguyen, L.V.5
Srinivas, P.6
Bell, B.D.7
Luhrs, K.A.8
Lane, T.E.9
Salvesen, G.S.10
-
48
-
-
33846839443
-
Deletion of NEMO/IKKg in liver parenchymal cells causes steatohepatitis and hepatocellular carcinoma
-
Luedde T., Beraza N, Kotsikoris V, van Loo G, Nenci A, De Vos R, Roskams T, Trautwein C, Pasparakis M. 2007. Deletion of NEMO/IKKg in liver parenchymal cells causes steatohepatitis and hepatocellular carcinoma. Cancer Cell 11: 119-132.
-
(2007)
Cancer Cell
, vol.11
, pp. 119-132
-
-
Luedde, T.1
Beraza, N.2
Kotsikoris, V.3
van Loo, G.4
Nenci, A.5
de Vos, R.6
Roskams, T.7
Trautwein, C.8
Pasparakis, M.9
-
50
-
-
2442642691
-
RIP1 is an essential mediator of Toll-like receptor 3-induced NF-kB activation
-
Meylan E., Burns K, Hofmann K, Blancheteau V, Martinon F, Kelliher M., Tschopp J. 2004. RIP1 is an essential mediator of Toll-like receptor 3-induced NF-kB activation. Nat Immunol 5: 503-507.
-
(2004)
Nat Immunol
, vol.5
, pp. 503-507
-
-
Meylan, E.1
Burns, K.2
Hofmann, K.3
Blancheteau, V.4
Martinon, F.5
Kelliher, M.6
Tschopp, J.7
-
51
-
-
78449269290
-
Caspase-1-induced pyroptosis is an innate immune effector mechanism against intracellular bacteria
-
Miao E. A, Leaf IA, Treuting PM, Mao DP, Dors M, Sarkar A, Warren S. E, Wewers MD, Aderem A. 2010. Caspase-1-induced pyroptosis is an innate immune effector mechanism against intracellular bacteria. Nat Immunol 11: 1136-1142.
-
(2010)
Nat Immunol
, vol.11
, pp. 1136-1142
-
-
Miao, E.A.1
Leaf, I.A.2
Treuting, P.M.3
Mao, D.P.4
Dors, M.5
Sarkar, A.6
Warren, S.E.7
Wewers, M.D.8
Aderem, A.9
-
52
-
-
84859424337
-
IAPs limit activation of RIP kinases by TNF receptor 1 during development
-
Moulin M., Anderton H, Voss AK, Thomas T, Wong WW, Bankovacki A., Feltham R, Chau D, Cook WD, Silke J, et al. 2012. IAPs limit activation of RIP kinases by TNF receptor 1 during development. EMBO J 31: 1679-1691.
-
(2012)
EMBO J
, vol.31
, pp. 1679-1691
-
-
Moulin, M.1
Anderton, H.2
Voss, A.K.3
Thomas, T.4
Wong, W.W.5
Bankovacki, A.6
Feltham, R.7
Chau, D.8
Cook, W.D.9
Silke, J.10
-
53
-
-
84865973897
-
Receptor interacting protein kinase mediates necrotic cone but not rod cell death in a mouse model of inherited degeneration
-
Murakami Y., Matsumoto H, Roh M, Suzuki J, Hisatomi T, Ikeda Y, Miller JW, Vavvas DG. 2012. Receptor interacting protein kinase mediates necrotic cone but not rod cell death in a mouse model of inherited degeneration. Proc Natl Acad Sci 109: 14598-14603.
-
(2012)
Proc Natl Acad Sci
, vol.109
, pp. 14598-14603
-
-
Murakami, Y.1
Matsumoto, H.2
Roh, M.3
Suzuki, J.4
Hisatomi, T.5
Ikeda, Y.6
Miller, J.W.7
Vavvas, D.G.8
-
54
-
-
84870999850
-
The NAD-dependent deacetylase SIRT2 is required for programmed necrosis
-
Narayan N., Lee IH, Borenstein R, Sun J, Wong R, Tong G, Fergusson M. M, Liu J, Rovira II, Cheng HL, et al. 2012. The NAD-dependent deacetylase SIRT2 is required for programmed necrosis. Nature 492: 199-204.
-
(2012)
Nature
, vol.492
, pp. 199-204
-
-
Narayan, N.1
Lee, I.H.2
Borenstein, R.3
Sun, J.4
Wong, R.5
Tong, G.6
Fergusson, M.M.7
Liu, J.8
Rovira II9
Cheng, H.L.10
-
55
-
-
0032472916
-
A dominant interfering mutant of FADD/MORT1 enhances deletion of autoreactive thymocytes and inhibits proliferation of mature T lymphocytes
-
Newton K., Harris AW, Bath ML, Smith KG, Strasser A. 1998. A dominant interfering mutant of FADD/MORT1 enhances deletion of autoreactive thymocytes and inhibits proliferation of mature T lymphocytes. EMBO J 17: 706-718.
-
(1998)
EMBO J
, vol.17
, pp. 706-718
-
-
Newton, K.1
Harris, A.W.2
Bath, M.L.3
Smith, K.G.4
Strasser, A.5
-
56
-
-
0842304221
-
Kinase RIP3 is dispensable for normal NF-kBs, signaling by the B-cell and T-cell receptors, tumor necrosis factor receptor 1, and Toll-like receptors 2 and 4
-
Newton K., Sun X, Dixit VM. 2004. Kinase RIP3 is dispensable for normal NF-kBs, signaling by the B-cell and T-cell receptors, tumor necrosis factor receptor 1, and Toll-like receptors 2 and 4. Mol Cell Biol 24: 1464-1469.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 1464-1469
-
-
Newton, K.1
Sun, X.2
Dixit, V.M.3
-
57
-
-
79952810024
-
Catalytic activity of the caspase-8-FLIP(L) complex inhibits RIPK3-dependent necrosis
-
Oberst A., Dillon CP, Weinlich R, McCormick LL, Fitzgerald P, Pop C., Hakem R, Salvesen GS, Green DR. 2011. Catalytic activity of the caspase-8-FLIP(L) complex inhibits RIPK3-dependent necrosis. Nature 471: 363-367.
-
(2011)
Nature
, vol.471
, pp. 363-367
-
-
Oberst, A.1
Dillon, C.P.2
Weinlich, R.3
McCormick, L.L.4
Fitzgerald, P.5
Pop, C.6
Hakem, R.7
Salvesen, G.S.8
Green, D.R.9
-
58
-
-
84856160569
-
Caspase 8 inhibits programmed necrosis by processing CYLD
-
O'Donnell MA, Perez-Jimenez E, Oberst A, Ng A, Massoumi R, Xavier R., Green DR, Ting AT. 2011. Caspase 8 inhibits programmed necrosis by processing CYLD. Nat Cell Biol 13: 1437-1442.
-
(2011)
Nat Cell Biol
, vol.13
, pp. 1437-1442
-
-
O'Donnell, M.A.1
Perez-Jimenez, E.2
Oberst, A.3
Ng, A.4
Massoumi, R.5
Xavier, R.6
Green, D.R.7
Ting, A.T.8
-
59
-
-
84864389178
-
NEMO inhibits programmed necrosis in an NFkB-independent manner by restraining RIP1
-
O'Donnell MA, Hase H, Legarda D, Ting AT. 2012. NEMO inhibits programmed necrosis in an NFkB-independent manner by restraining RIP1. PLoS ONE 7: e41238.
-
(2012)
PLoS ONE
, vol.7
-
-
O'Donnell, M.A.1
Hase, H.2
Legarda, D.3
Ting, A.T.4
-
60
-
-
77955609495
-
Fas-associated death domain (FADD) is a negative regulator of T-cell receptor-mediated necroptosis
-
Osborn S. L, Diehl G, Han SJ, Xue L, Kurd N, Hsieh K, Cado D, Robey E. A, Winoto A. 2010. Fas-associated death domain (FADD) is a negative regulator of T-cell receptor-mediated necroptosis. Proc Natl Acad Sci 107: 13034-13039.
-
(2010)
Proc Natl Acad Sci
, vol.107
, pp. 13034-13039
-
-
Osborn, S.L.1
Diehl, G.2
Han, S.J.3
Xue, L.4
Kurd, N.5
Hsieh, K.6
Cado, D.7
Robey, E.A.8
Winoto, A.9
-
61
-
-
68249113997
-
DAI/ ZBP1 recruits RIP1 and RIP3 through RIP homotypic interaction motifs to activate NF-kB
-
Rebsamen M., Heinz LX, Meylan E, Michallet MC, Schroder K, Hofmann K., Vazquez J, Benedict CA, Tschopp J. 2009. DAI/ ZBP1 recruits RIP1 and RIP3 through RIP homotypic interaction motifs to activate NF-kB. EMBO Rep 10: 916-922.
-
(2009)
EMBO Rep
, vol.10
, pp. 916-922
-
-
Rebsamen, M.1
Heinz, L.X.2
Meylan, E.3
Michallet, M.C.4
Schroder, K.5
Hofmann, K.6
Vazquez, J.7
Benedict, C.A.8
Tschopp, J.9
-
62
-
-
84866544929
-
Type I interferon induces necroptosis in macrophages during infection with Salmonella enterica serovar Typhimurium
-
Robinson N., McComb S, Mulligan R, Dudani R, Krishnan L, Sad S. 2012. Type I interferon induces necroptosis in macrophages during infection with Salmonella enterica serovar Typhimurium. Nat Immunol 13: 954-962.
-
(2012)
Nat Immunol
, vol.13
, pp. 954-962
-
-
Robinson, N.1
McComb, S.2
Mulligan, R.3
Dudani, R.4
Krishnan, L.5
Sad, S.6
-
63
-
-
84876699484
-
Absence of receptor interacting protein kinase 3 prevents ethanol-induced liver injury
-
Roychowdhury S., McMullen MR, Pisano SG, Liu X, Nagy LE. 2013. Absence of receptor interacting protein kinase 3 prevents ethanol-induced liver injury. Hepatology 57: 1773-1783.
-
(2013)
Hepatology
, vol.57
, pp. 1773-1783
-
-
Roychowdhury, S.1
McMullen, M.R.2
Pisano, S.G.3
Liu, X.4
Nagy, L.E.5
-
64
-
-
0037380628
-
Essential role for caspase 8 in T-cell homeostasis and T-cell-mediated immunity
-
Salmena L., Lemmers B, Hakem A, Matysiak-Zablocki E, Murakami K., Au PY, Berry DM, Tamblyn L, Shehabeldin A, Migon E, et al. 2003. Essential role for caspase 8 in T-cell homeostasis and T-cell-mediated immunity. Genes Dev 17: 883-895.
-
(2003)
Genes Dev
, vol.17
, pp. 883-895
-
-
Salmena, L.1
Lemmers, B.2
Hakem, A.3
Matysiak-Zablocki, E.4
Murakami, K.5
Au, P.Y.6
Berry, D.M.7
Tamblyn, L.8
Shehabeldin, A.9
Migon, E.10
-
65
-
-
84875138006
-
Inhibitor of apoptosis (IAP) proteinsmodulators of cell death and inflammation
-
Silke J., Meier P. 2013. Inhibitor of apoptosis (IAP) proteinsmodulators of cell death and inflammation. Cold Spring Harb Perspect Biol 5: a008730.
-
(2013)
Cold Spring Harb Perspect Biol
, vol.5
-
-
Silke, J.1
Meier, P.2
-
66
-
-
84892809449
-
TNF-induced necroptosis and PARP-1-mediated necrosis represent distinct routes to programmed necrotic cell death
-
doi: 10.1007/s00018-013-1381-6
-
Sosna J., Voigt S, Mathieu S, Lange A, Thon L, Davarnia P, Herdegen T., Linkermann A, Rittger A, Chan FK, et al. 2013. TNF-induced necroptosis and PARP-1-mediated necrosis represent distinct routes to programmed necrotic cell death. Cell Mol Life Sci doi: 10.1007/s00018-013-1381-6.
-
(2013)
Cell Mol Life Sci
-
-
Sosna, J.1
Voigt, S.2
Mathieu, S.3
Lange, A.4
Thon, L.5
Davarnia, P.6
Herdegen, T.7
Linkermann, A.8
Rittger, A.9
Chan, F.K.10
-
67
-
-
0017618537
-
Post-embryonic cell lineages of the nematode, Caenorhabditis elegans
-
Sulston J. E, Horvitz HR. 1977. Post-embryonic cell lineages of the nematode, Caenorhabditis elegans. Dev Biol 56: 110-156.
-
(1977)
Dev Biol
, vol.56
, pp. 110-156
-
-
Sulston, J.E.1
Horvitz, H.R.2
-
68
-
-
0033546276
-
RIP3, a novel apoptosis-inducing kinase
-
Sun X., Lee J, Navas T, Baldwin DT, Stewart TA, Dixit VM. 1999. RIP3, a novel apoptosis-inducing kinase. J Biol Chem 274: 16871-16875.
-
(1999)
J Biol Chem
, vol.274
, pp. 16871-16875
-
-
Sun, X.1
Lee, J.2
Navas, T.3
Baldwin, D.T.4
Stewart, T.A.5
Dixit, V.M.6
-
69
-
-
0037088632
-
Identification of a novel homotypic interaction motif required for the phosphorylation of receptor-interacting protein (RIP) by RIP3
-
Sun X., Yin J, Starovasnik MA, Fairbrother WJ, Dixit VM. 2002. Identification of a novel homotypic interaction motif required for the phosphorylation of receptor-interacting protein (RIP) by RIP3. J Biol Chem 277: 9505-9511.
-
(2002)
J Biol Chem
, vol.277
, pp. 9505-9511
-
-
Sun, X.1
Yin, J.2
Starovasnik, M.A.3
Fairbrother, W.J.4
Dixit, V.M.5
-
70
-
-
84862907788
-
Mixed lineage kinase domain-like protein mediates necrosis signaling downstream of RIP3 kinase
-
Sun L., Wang H, Wang Z, He S, Chen S, Liao D, Wang L, Yan J, Liu W., Lei X, et al. 2012. Mixed lineage kinase domain-like protein mediates necrosis signaling downstream of RIP3 kinase. Cell 148: 213-227.
-
(2012)
Cell
, vol.148
, pp. 213-227
-
-
Sun, L.1
Wang, H.2
Wang, Z.3
He, S.4
Chen, S.5
Liao, D.6
Wang, L.7
Yan, J.8
Liu, W.9
Lei, X.10
-
71
-
-
72949116358
-
Macrophage death and defective inflammation resolution in atherosclerosis
-
Tabas I. 2010. Macrophage death and defective inflammation resolution in atherosclerosis. Nat Rev Immunol 10: 36-46.
-
(2010)
Nat Rev Immunol
, vol.10
, pp. 36-46
-
-
Tabas, I.1
-
72
-
-
33644763298
-
Inhibition of ADP/ATP exchange in receptor-interacting protein-mediated necrosis
-
Temkin V., Huang Q, Liu H, Osada H, Pope RM. 2006. Inhibition of ADP/ATP exchange in receptor-interacting protein-mediated necrosis. Mol Cell Biol 26: 2215-2225.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 2215-2225
-
-
Temkin, V.1
Huang, Q.2
Liu, H.3
Osada, H.4
Pope, R.M.5
-
73
-
-
79960921946
-
The Ripoptosome, a signaling platform that assembles in response to genotoxic stress and loss of IAPs
-
Tenev T., Bianchi K, Darding M, Broemer M, Langlais C, Wallberg F., Zachariou A, Lopez J, MacFarlane M, Cain K, et al. 2011. The Ripoptosome, a signaling platform that assembles in response to genotoxic stress and loss of IAPs. Mol Cell 43: 432-448.
-
(2011)
Mol Cell
, vol.43
, pp. 432-448
-
-
Tenev, T.1
Bianchi, K.2
Darding, M.3
Broemer, M.4
Langlais, C.5
Wallberg, F.6
Zachariou, A.7
Lopez, J.8
McFarlane, M.9
Cain, K.10
-
74
-
-
78650718758
-
Receptor interacting protein kinases mediate retinal detachmentinduced photoreceptor necrosis and compensate for inhibition of apoptosis
-
Trichonas G., Murakami Y, Thanos A, Morizane Y, Kayama M, Debouck C. M, Hisatomi T, Miller JW, Vavvas DG. 2010. Receptor interacting protein kinases mediate retinal detachmentinduced photoreceptor necrosis and compensate for inhibition of apoptosis. Proc Natl Acad Sci 107: 21695-21700.
-
(2010)
Proc Natl Acad Sci
, vol.107
, pp. 21695-21700
-
-
Trichonas, G.1
Murakami, Y.2
Thanos, A.3
Morizane, Y.4
Kayama, M.5
Debouck, C.M.6
Hisatomi, T.7
Miller, J.W.8
Vavvas, D.G.9
-
75
-
-
47749133767
-
Cytomegalovirus M45 cell death suppression requires receptor-interacting protein (RIP) homotypic interaction motif (RHIM)-dependent interaction with RIP1
-
Upton J. W, Kaiser WJ, Mocarski ES. 2008. Cytomegalovirus M45 cell death suppression requires receptor-interacting protein (RIP) homotypic interaction motif (RHIM)-dependent interaction with RIP1. J Biol Chem 283: 16966-16970.
-
(2008)
J Biol Chem
, vol.283
, pp. 16966-16970
-
-
Upton, J.W.1
Kaiser, W.J.2
Mocarski, E.S.3
-
77
-
-
84858420051
-
DAI/ZBP1/DLM-1 complexes with RIP3 to mediate virus-induced programmed necrosis that is targeted by murine cytomegalovirus vIRA
-
Upton J. W, Kaiser WJ, Mocarski ES. 2012. DAI/ZBP1/DLM-1 complexes with RIP3 to mediate virus-induced programmed necrosis that is targeted by murine cytomegalovirus vIRA. Cell Host Microbe 11: 290-297.
-
(2012)
Cell Host Microbe
, vol.11
, pp. 290-297
-
-
Upton, J.W.1
Kaiser, W.J.2
Mocarski, E.S.3
-
79
-
-
0032143986
-
Targeted disruption of the mouse Caspase 8 gene ablates cell death induction by the TNF receptors, Fas/Apo1, and DR3 and is lethal prenatally
-
Varfolomeev E. E, Schuchmann M, Luria V, Chiannilkulchai N, Beckmann J. S, Mett IL, Rebrikov D, Brodianski VM, Kemper OC, Kollet O, et al. 1998. Targeted disruption of the mouse Caspase 8 gene ablates cell death induction by the TNF receptors, Fas/Apo1, and DR3 and is lethal prenatally. Immunity 9: 267-276.
-
(1998)
Immunity
, vol.9
, pp. 267-276
-
-
Varfolomeev, E.E.1
Schuchmann, M.2
Luria, V.3
Chiannilkulchai, N.4
Beckmann, J.S.5
Mett, I.L.6
Rebrikov, D.7
Brodianski, V.M.8
Kemper, O.C.9
Kollet, O.10
-
80
-
-
84857404572
-
Inhibitor of apoptosis proteins limit RIP3 kinase-dependent interleukin-1 activation
-
Vince J. E, Wong WW, Gentle I, Lawlor KE, Allam R, O'Reilly L, Mason K., Gross O, Ma S, Guarda G, et al. 2012. Inhibitor of apoptosis proteins limit RIP3 kinase-dependent interleukin-1 activation. Immunity 36: 215-227.
-
(2012)
Immunity
, vol.36
, pp. 215-227
-
-
Vince, J.E.1
Wong, W.W.2
Gentle, I.3
Lawlor, K.E.4
Allam, R.5
O'Reilly, L.6
Mason, K.7
Gross, O.8
Ma, S.9
Guarda, G.10
-
81
-
-
0032055344
-
A role for FADD in T cell activation and development
-
Walsh C. M, Wen BG, Chinnaiyan AM, O'Rourke K, Dixit VM, Hedrick SM. 1998. A role for FADD in T cell activation and development. Immunity 8: 439-449.
-
(1998)
Immunity
, vol.8
, pp. 439-449
-
-
Walsh, C.M.1
Wen, B.G.2
Chinnaiyan, A.M.3
O'Rourke, K.4
Dixit, V.M.5
Hedrick, S.M.6
-
82
-
-
43049152912
-
TNF-a induces two distinct caspase-8 activation pathways
-
Wang L., Du F, Wang X. 2008. TNF-a induces two distinct caspase-8 activation pathways. Cell 133: 693-703.
-
(2008)
Cell
, vol.133
, pp. 693-703
-
-
Wang, L.1
Du, F.2
Wang, X.3
-
83
-
-
84862909353
-
The mitochondrial phosphatase PGAM5 functions at the convergence point of multiple necrotic death pathways
-
Wang Z., Jiang H, Chen S, Du F, Wang X. 2012. The mitochondrial phosphatase PGAM5 functions at the convergence point of multiple necrotic death pathways. Cell 148: 228-243.
-
(2012)
Cell
, vol.148
, pp. 228-243
-
-
Wang, Z.1
Jiang, H.2
Chen, S.3
Du, F.4
Wang, X.5
-
84
-
-
0035957653
-
Proapoptotic BAX and BAK: A requisite gateway to mitochondrial dysfunction and death
-
Wei M. C, Zong WX, Cheng EH, Lindsten T, Panoutsakopoulou V, Ross AJ, Roth KA, MacGregor GR, Thompson CB, Korsmeyer SJ. 2001. Proapoptotic BAX and BAK: A requisite gateway to mitochondrial dysfunction and death. Science 292: 727-730.
-
(2001)
Science
, vol.292
, pp. 727-730
-
-
Wei, M.C.1
Zong, W.X.2
Cheng, E.H.3
Lindsten, T.4
Panoutsakopoulou, V.5
Ross, A.J.6
Roth, K.A.7
McGregor, G.R.8
Thompson, C.B.9
Korsmeyer, S.J.10
-
85
-
-
80052850704
-
FADD prevents RIP3-mediated epithelial cell necrosis and chronic intestinal inflammation
-
Welz P. S, Wullaert A, Vlantis K, Kondylis V, Fernandez-Majada V, Ermolaeva M, Kirsch P, Sterner-Kock A, van Loo G, Pasparakis M. 2011. FADD prevents RIP3-mediated epithelial cell necrosis and chronic intestinal inflammation. Nature 477: 330-334.
-
(2011)
Nature
, vol.477
, pp. 330-334
-
-
Welz, P.S.1
Wullaert, A.2
Vlantis, K.3
Kondylis, V.4
Fernandez-Majada, V.5
Ermolaeva, M.6
Kirsch, P.7
Sterner-Kock, A.8
van Loo, G.9
Pasparakis, M.10
-
86
-
-
84874860953
-
Structural basis of RIP1 inhibition by necrostatins
-
Xie T., Peng W, Liu Y, Yan C, Maki J, Degterev A, Yuan J, Shi Y. 2013. Structural basis of RIP1 inhibition by necrostatins. Structure 21: 493-499.
-
(2013)
Structure
, vol.21
, pp. 493-499
-
-
Xie, T.1
Peng, W.2
Liu, Y.3
Yan, C.4
Maki, J.5
Degterev, A.6
Yuan, J.7
Shi, Y.8
-
87
-
-
7144263731
-
FADD: Essential for embryo development and signaling from some, but not all, inducers of apoptosis
-
Yeh W. C, Pompa JL, McCurrach ME, Shu HB, Elia AJ, Shahinian A, Ng M, Wakeham A, Khoo W, Mitchell K, et al. 1998. FADD: Essential for embryo development and signaling from some, but not all, inducers of apoptosis. Science 279: 1954-1958.
-
(1998)
Science
, vol.279
, pp. 1954-1958
-
-
Yeh, W.C.1
Pompa, J.L.2
McCurrach, M.E.3
Shu, H.B.4
Elia, A.J.5
Shahinian, A.6
Ng, M.7
Wakeham, A.8
Khoo, W.9
Mitchell, K.10
-
88
-
-
0033662341
-
Requirement for Casper (c-FLIP) in regulation of death receptor-induced apoptosis and embryonic development
-
Yeh W. C, Itie A, Elia AJ, Ng M, Shu HB, Wakeham A, Mirtsos C, Suzuki N., Bonnard M, Goeddel DV, et al. 2000. Requirement for Casper (c-FLIP) in regulation of death receptor-induced apoptosis and embryonic development. Immunity 12: 633-642.
-
(2000)
Immunity
, vol.12
, pp. 633-642
-
-
Yeh, W.C.1
Itie, A.2
Elia, A.J.3
Ng, M.4
Shu, H.B.5
Wakeham, A.6
Mirtsos, C.7
Suzuki, N.8
Bonnard, M.9
Goeddel, D.V.10
-
89
-
-
84879799191
-
Commensal microbiota are required for systemic inflammation triggered by necrotic dendritic cells
-
Young J. A, He TH, Reizis B, Winoto A. 2013. Commensal microbiota are required for systemic inflammation triggered by necrotic dendritic cells. Cell reports 3: 1932-1944.
-
(2013)
Cell reports
, vol.3
, pp. 1932-1944
-
-
Young, J.A.1
He, T.H.2
Reizis, B.3
Winoto, A.4
-
90
-
-
0033587070
-
Identification of RIP3, a RIP-like kinase that activates apoptosis and NFkB
-
Yu P. W, Huang BC, Shen M, Quast J, Chan E, Xu X, Nolan GP, Payan D. G, Luo Y. 1999. Identification of RIP3, a RIP-like kinase that activates apoptosis and NFkB. Curr Biol 9: 539-542.
-
(1999)
Curr Biol
, vol.9
, pp. 539-542
-
-
Yu, P.W.1
Huang, B.C.2
Shen, M.3
Quast, J.4
Chan, E.5
Xu, X.6
Nolan, G.P.7
Payan, D.G.8
Luo, Y.9
-
91
-
-
0032546387
-
Fasmediated apoptosis and activation-induced T-cell proliferation are defective in mice lacking FADD/Mort1
-
Zhang J., Cado D, Chen A, Kabra NH, Winoto A. 1998. Fasmediated apoptosis and activation-induced T-cell proliferation are defective in mice lacking FADD/Mort1. Nature 392: 296-300.
-
(1998)
Nature
, vol.392
, pp. 296-300
-
-
Zhang, J.1
Cado, D.2
Chen, A.3
Kabra, N.H.4
Winoto, A.5
-
92
-
-
23844548539
-
Conditional Fas-associated death domain protein (FADD): GFP knockout mice reveal FADD is dispensable in thymic development but essential in peripheral Tcell homeostasis
-
Zhang Y., Rosenberg S, Wang H, Imtiyaz HZ, Hou YJ, Zhang J. 2005. Conditional Fas-associated death domain protein (FADD): GFP knockout mice reveal FADD is dispensable in thymic development but essential in peripheral Tcell homeostasis. J Immunol 175: 3033-3044.
-
(2005)
J Immunol
, vol.175
, pp. 3033-3044
-
-
Zhang, Y.1
Rosenberg, S.2
Wang, H.3
Imtiyaz, H.Z.4
Hou, Y.J.5
Zhang, J.6
-
93
-
-
67650812332
-
RIP3, an energy metabolism regulator that switches TNF-induced cell death from apoptosis to necrosis
-
Zhang D. W, Shao J, Lin J, Zhang N, Lu BJ, Lin SC, Dong MQ, Han J. 2009. RIP3, an energy metabolism regulator that switches TNF-induced cell death from apoptosis to necrosis. Science 325: 332-336.
-
(2009)
Science
, vol.325
, pp. 332-336
-
-
Zhang, D.W.1
Shao, J.2
Lin, J.3
Zhang, N.4
Lu, B.J.5
Lin, S.C.6
Dong, M.Q.7
Han, J.8
-
94
-
-
79952780505
-
Functional complementation between FADD and RIP1 in embryos and lymphocytes
-
Zhang H., Zhou X, McQuade T, Li J, Chan FK, Zhang J. 2011. Functional complementation between FADD and RIP1 in embryos and lymphocytes. Nature 471: 373-376.
-
(2011)
Nature
, vol.471
, pp. 373-376
-
-
Zhang, H.1
Zhou, X.2
McQuade, T.3
Li, J.4
Chan, F.K.5
Zhang, J.6
-
95
-
-
84859467770
-
Mixed lineage kinase domain-like is a key receptor interacting protein 3 downstream component of TNF-induced necrosis
-
Zhao J., Jitkaew S, Cai Z, Choksi S, Li Q, Luo J, Liu ZG. 2012. Mixed lineage kinase domain-like is a key receptor interacting protein 3 downstream component of TNF-induced necrosis. Proc Natl Acad Sci 109: 5322-5327.
-
(2012)
Proc Natl Acad Sci
, vol.109
, pp. 5322-5327
-
-
Zhao, J.1
Jitkaew, S.2
Cai, Z.3
Choksi, S.4
Li, Q.5
Luo, J.6
Liu, Z.G.7
-
96
-
-
2642536197
-
Alkylating DNA damage stimulates a regulated form of necrotic cell death
-
Zong W. X, Ditsworth D, Bauer DE, Wang ZQ, Thompson CB. 2004. Alkylating DNA damage stimulates a regulated form of necrotic cell death. Genes Dev 18: 1272-1282.
-
(2004)
Genes Dev
, vol.18
, pp. 1272-1282
-
-
Zong, W.X.1
Ditsworth, D.2
Bauer, D.E.3
Wang, Z.Q.4
Thompson, C.B.5
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