Loss of caspase-8 protects mice against inflammation-related hepatocarcinogenesis but induces non-apoptotic liver injury

Gastroenterology

Volumn 141, Issue 6, 2011, Pages 2176-2187

  Liedtke, Christian ^a   Bangen, Jörg Martin ^a   Freimuth, Julia ^a   Beraza, Naiara ^a   Lambertz, Daniela ^a   Cubero, Francisco J ^a   Hatting, Maximilian ^a   Karlmark, Karlin R ^a   Streetz, Konrad L ^a   Krombach, Gabriele A ^b   Tacke, Frank ^a   Gassler, Nikolaus ^a   Riethmacher, Dieter ^c   Trautwein, Christian ^a  

^a UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

^b JUSTUS LIEBIG UNIVERSITY   (Germany)

^c UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

Author keywords

FADD; Fas associated Protein With Death Domain; Inflammation; TNF Signaling; Tumor Necrosis Factor

Indexed keywords

CASPASE 8; CONCANAVALIN A; FAS ANTIBODY; FAS ANTIGEN; I KAPPA B KINASE GAMMA; LIPOPOLYSACCHARIDE;

ABLATION THERAPY; AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CHOLESTASIS; COMPLEX FORMATION; CONTROLLED STUDY; ENZYME INHIBITION; FATTY LIVER; GENE DELETION; HEPATITIS; INFLAMMATION; LIVER CARCINOGENESIS; LIVER INJURY; LIVER NECROSIS; LIVER PARENCHYMA; MALE; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PHENOTYPE; PRIORITY JOURNAL; T LYMPHOCYTE;

EID: 81855183262     PISSN: 00165085     EISSN: 15280012     Source Type: Journal    
DOI: 10.1053/j.gastro.2011.08.037     Document Type: Article

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