Mitochondrial DNA damage induces apoptosis in senescent cells

Cell Death and Disease

Volumn 4, Issue 7, 2013, Pages

  Laberge, R M ^a   Adler, D ^b   DeMaria, M ^a   Mechtouf, N ^c   Teachenor, R ^b   Cardin, G B ^c   Desprez, P Y ^a,d   Campisi, J ^a,b   Rodier, F ^a,b,c  

^a BUCK INSTITUTE FOR RESEARCH ON AGING   (United States)

^b LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

^c UNIVERSITÉ DE MONTRÉAL   (Canada)

^d CALIFORNIA PACIFIC MEDICAL CENTER   (United States)

Author keywords

Aging; Ganciclovir; Herpes simplex virus thymidine kinase; Mitochondria; Nuclear DNA damage foci; Tumorigenesis

Indexed keywords

CASPASE; GANCICLOVIR; MITOCHONDRIAL DNA; THYMIDINE KINASE;

ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; CANCER CELL; CANCER COMBINATION CHEMOTHERAPY; CELL AGING; CELL KILLING; CONTROLLED STUDY; DNA DAMAGE; DRUG EFFECT; FIBROBLAST; HERPES SIMPLEX VIRUS; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL;

EID: 84881047401     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2013.199     Document Type: Article

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