Fenofibrate inhibits intestinal Cl- secretion by blocking basolateral KCNQ1 K+ channels

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 293, Issue 6, 2007, Pages

  Bajwa, Poonam J ^a,b   Alioua, Abderrahmane ^c   Lee, Jimmy W ^a,b   Straus, Daniel S ^a,b   Toro, Ligia ^c   Lytle, Christian ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Antidiarrheal agents; Clofibrate; Human T84 cells; K v7.1; KvLQT1; KCNE3; MiRP2; Mouse intestine; Peroxisome proliferator activated receptor ; Secretory diarrhea

Indexed keywords

CLOFIBRATE; FENOFIBRATE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; POTASSIUM CHANNEL KCNQ1;

ADENOCARCINOMA; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL STRAIN HEK293; COLON MUCOSA; CONTROLLED STUDY; DIARRHEA; ENZYME ACTIVITY; FEMALE; HUMAN; HUMAN CELL; INTESTINE SECRETION; ION TRANSPORT; MEMBRANE PERMEABILITY; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL;

ANTILIPEMIC AGENTS; CALCIUM CHANNEL BLOCKERS; CELL LINE; CHLORINE; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; INTESTINAL MUCOSA; ION CHANNEL GATING; KCNQ1 POTASSIUM CHANNEL; PROCETOFEN;

EID: 37149046032     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00234.2007     Document Type: Article

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