-
1
-
-
80051846043
-
Structural Studies of Amyloid
-
Eisenberg, D.; Nelson, R.; Sawaya, M. R.; Balbirnie, M.; Madsen, A.; Riekel, C.; Sambashivan, S.; Liu, Y.; Gingery, M.; Grothe, R. Structural Studies of Amyloid FEBS J. 2005, 272, 78-79
-
(2005)
FEBS J.
, vol.272
, pp. 78-79
-
-
Eisenberg, D.1
Nelson, R.2
Sawaya, M.R.3
Balbirnie, M.4
Madsen, A.5
Riekel, C.6
Sambashivan, S.7
Liu, Y.8
Gingery, M.9
Grothe, R.10
-
2
-
-
84863229747
-
Atomic View of a Toxic Amyloid Small Oligomer
-
Laganowsky, A.; Liu, C.; Sawaya, M. R.; Whitelegge, J. P.; Park, J.; Zhao, M. L.; Pensalfini, A.; Soriaga, A. B.; Landau, M.; Teng, P. K.; Cascio, D.; Glabe, C.; Eisenberg, D. Atomic View of a Toxic Amyloid Small Oligomer Science 2012, 335, 1228-1231
-
(2012)
Science
, vol.335
, pp. 1228-1231
-
-
Laganowsky, A.1
Liu, C.2
Sawaya, M.R.3
Whitelegge, J.P.4
Park, J.5
Zhao, M.L.6
Pensalfini, A.7
Soriaga, A.B.8
Landau, M.9
Teng, P.K.10
Cascio, D.11
Glabe, C.12
Eisenberg, D.13
-
3
-
-
57749098600
-
Amyloid Formation by Globular Proteins under Native Conditions
-
Chiti, F.; Dobson, C. M. Amyloid Formation by Globular Proteins under Native Conditions Nat. Chem. Biol. 2008, 5, 15-21
-
(2008)
Nat. Chem. Biol.
, vol.5
, pp. 15-21
-
-
Chiti, F.1
Dobson, C.M.2
-
4
-
-
0035297712
-
Targeting Small a β Oligomers: The Solution to an Alzheimer's Disease Conundrum?
-
Klein, W. L.; Krafft, G. A.; Finch, C. E. Targeting Small a β Oligomers: The Solution to an Alzheimer's Disease Conundrum? Trends Neurosci. 2001, 24, 219-224
-
(2001)
Trends Neurosci.
, vol.24
, pp. 219-224
-
-
Klein, W.L.1
Krafft, G.A.2
Finch, C.E.3
-
5
-
-
0021271971
-
Clinical Diagnosis of Alzheimer's Disease: Report of the Nincds-Adrda Work Group under the Auspices of Department of Health and Human Services Task Force on Alzheimer's Disease
-
McKhann, G.; Drachman, D.; Folstein, M.; Katzman, R.; Price, D.; Stadlan, E. M. Clinical Diagnosis of Alzheimer's Disease: Report of the Nincds-Adrda Work Group under the Auspices of Department of Health and Human Services Task Force on Alzheimer's Disease Neurology 1984, 34, 939-944
-
(1984)
Neurology
, vol.34
, pp. 939-944
-
-
McKhann, G.1
Drachman, D.2
Folstein, M.3
Katzman, R.4
Price, D.5
Stadlan, E.M.6
-
6
-
-
33847662852
-
Soluble Protein Oligomers in Neurodegeneration: Lessons from the Alzheimer's Amyloid β-Peptide
-
Haass, C.; Selkoe, D. J. Soluble Protein Oligomers in Neurodegeneration: Lessons from the Alzheimer's Amyloid β-Peptide Nat. Rev. Mol. Cell Biol. 2007, 8, 101-112
-
(2007)
Nat. Rev. Mol. Cell Biol.
, vol.8
, pp. 101-112
-
-
Haass, C.1
Selkoe, D.J.2
-
7
-
-
5044235541
-
Prediction of Sequence-Dependent and Mutational Effects on the Aggregation of Peptides and Proteins
-
Fernandez-Escamilla, A. M.; Rousseau, F.; Schymkowitz, J.; Serrano, L. Prediction of Sequence-Dependent and Mutational Effects on the Aggregation of Peptides and Proteins Nat. Biotechnol. 2004, 22, 1302-1306
-
(2004)
Nat. Biotechnol.
, vol.22
, pp. 1302-1306
-
-
Fernandez-Escamilla, A.M.1
Rousseau, F.2
Schymkowitz, J.3
Serrano, L.4
-
8
-
-
34249290108
-
Atomic Structures of Amyloid Cross-β Spines Reveal Varied Steric Zippers
-
Sawaya, M. R.; Sambashivan, S.; Nelson, R.; Ivanova, M. I.; Sievers, S. A.; Apostol, M. I.; Thompson, M. J.; Balbirnie, M.; Wiltzius, J. J. W.; McFarlane, H. T.; Madsen, A. O.; Riekel, C.; Eisenberg, D. Atomic Structures of Amyloid Cross-β Spines Reveal Varied Steric Zippers Nature 2007, 447, 453-457
-
(2007)
Nature
, vol.447
, pp. 453-457
-
-
Sawaya, M.R.1
Sambashivan, S.2
Nelson, R.3
Ivanova, M.I.4
Sievers, S.A.5
Apostol, M.I.6
Thompson, M.J.7
Balbirnie, M.8
Wiltzius, J.J.W.9
McFarlane, H.T.10
Madsen, A.O.11
Riekel, C.12
Eisenberg, D.13
-
9
-
-
79251631002
-
Ion Mobility-Mass Spectrometry Reveals a Conformational Conversion from Random Assembly to β-Sheet in Amyloid Fibril Formation
-
Bleiholder, C.; Dupuis, N. F.; Wyttenbach, T.; Bowers, M. T. Ion Mobility-Mass Spectrometry Reveals a Conformational Conversion from Random Assembly to β-Sheet in Amyloid Fibril Formation Nat. Chem. 2011, 3, 172-177
-
(2011)
Nat. Chem.
, vol.3
, pp. 172-177
-
-
Bleiholder, C.1
Dupuis, N.F.2
Wyttenbach, T.3
Bowers, M.T.4
-
10
-
-
0034681163
-
Acceleration of Oligomerization, Not Fibrillization, Is a Shared Property of Both α-Synuclein Mutations Linked to Early-Onset Parkinson's Disease: Implications for Pathogenesis and Therapy
-
Conway, K. A.; Lee, S. J.; Rochet, J. C.; Ding, T. T.; Williamson, R. E.; Lansbury, P. T. Acceleration of Oligomerization, Not Fibrillization, Is a Shared Property of Both α-Synuclein Mutations Linked to Early-Onset Parkinson's Disease: Implications for Pathogenesis and Therapy Proc. Natl. Acad. Sci. U.S.A. 2000, 97, 571-576
-
(2000)
Proc. Natl. Acad. Sci. U.S.A.
, vol.97
, pp. 571-576
-
-
Conway, K.A.1
Lee, S.J.2
Rochet, J.C.3
Ding, T.T.4
Williamson, R.E.5
Lansbury, P.T.6
-
11
-
-
33748525884
-
Computational Models for the Prediction of Polypeptide Aggregation Propensity
-
Caflisch, A. Computational Models for the Prediction of Polypeptide Aggregation Propensity Curr. Opin. Chem. Biol. 2006, 10, 437-444
-
(2006)
Curr. Opin. Chem. Biol.
, vol.10
, pp. 437-444
-
-
Caflisch, A.1
-
12
-
-
83755195619
-
Yeast Prions Assembly and Propagation Contributions of the Prion and Non-Prion Moieties and the Nature of Assemblies
-
Kabani, M.; Melki, R. Yeast Prions Assembly and Propagation Contributions of the Prion and Non-Prion Moieties and the Nature of Assemblies Prion 2011, 5, 277-284
-
(2011)
Prion
, vol.5
, pp. 277-284
-
-
Kabani, M.1
Melki, R.2
-
13
-
-
80054988967
-
Length-Dependent Aggregation of Uninterrupted Polyalanine Peptides
-
Bernacki, J. P.; Murphy, R. M. Length-Dependent Aggregation of Uninterrupted Polyalanine Peptides Biochemistry 2011, 50, 9200-9211
-
(2011)
Biochemistry
, vol.50
, pp. 9200-9211
-
-
Bernacki, J.P.1
Murphy, R.M.2
-
14
-
-
50049095633
-
Atomic Structure of the Cross-β Spine of Islet Amyloid Polypeptide (Amylin)
-
Wiltzius, J. J. W.; Sievers, S. A.; Sawaya, M. R.; Cascio, D.; Popov, D.; Riekel, C.; Eisenberg, D. Atomic Structure of the Cross-β Spine of Islet Amyloid Polypeptide (Amylin) Protein Sci. 2008, 17, 1467-1474
-
(2008)
Protein Sci.
, vol.17
, pp. 1467-1474
-
-
Wiltzius, J.J.W.1
Sievers, S.A.2
Sawaya, M.R.3
Cascio, D.4
Popov, D.5
Riekel, C.6
Eisenberg, D.7
-
15
-
-
33947728761
-
Cooperative Hydrogen Bonding in Amyloid Formation
-
Tsemekhman, K.; Goldschmidt, L.; Eisenberg, D.; Baker, D. Cooperative Hydrogen Bonding in Amyloid Formation Protein Sci. 2007, 16, 761-764
-
(2007)
Protein Sci.
, vol.16
, pp. 761-764
-
-
Tsemekhman, K.1
Goldschmidt, L.2
Eisenberg, D.3
Baker, D.4
-
16
-
-
0035956924
-
An Amyloid-Forming Peptide from the Yeast Prion Sup35 Reveals a Dehydrated Beta-Sheet Structure for Amyloid
-
Balbirnie, M.; Grothe, R.; Eisenberg, D. S. An Amyloid-Forming Peptide from the Yeast Prion Sup35 Reveals a Dehydrated Beta-Sheet Structure for Amyloid Proc. Natl. Acad. Sci. U.S.A. 2001, 98, 2375-2380
-
(2001)
Proc. Natl. Acad. Sci. U.S.A.
, vol.98
, pp. 2375-2380
-
-
Balbirnie, M.1
Grothe, R.2
Eisenberg, D.S.3
-
17
-
-
20444440728
-
Structure of the Cross-Beta Spine of Amyloid-Like Fibrils
-
Nelson, R.; Sawaya, M. R.; Balbirnie, M.; Madsen, A. O.; Riekel, C.; Grothe, R.; Eisenberg, D. Structure of the Cross-Beta Spine of Amyloid-Like Fibrils Nature 2005, 435, 773-778
-
(2005)
Nature
, vol.435
, pp. 773-778
-
-
Nelson, R.1
Sawaya, M.R.2
Balbirnie, M.3
Madsen, A.O.4
Riekel, C.5
Grothe, R.6
Eisenberg, D.7
-
18
-
-
80054752317
-
Molecular Basis for Amyloid-β Polymorphism
-
Colletier, J.-P.; Laganowsky, A.; Landau, M.; Zhao, M.; Soriaga, A. B.; Goldschmidt, L.; Flot, D.; Cascio, D.; Sawaya, M. R.; Eisenberg, D. Molecular Basis for Amyloid-β Polymorphism Proc. Natl. Acad. Sci. U.S.A. 2011, 16938-16943
-
(2011)
Proc. Natl. Acad. Sci. U.S.A.
, pp. 16938-16943
-
-
Colletier, J.-P.1
Laganowsky, A.2
Landau, M.3
Zhao, M.4
Soriaga, A.B.5
Goldschmidt, L.6
Flot, D.7
Cascio, D.8
Sawaya, M.R.9
Eisenberg, D.10
-
19
-
-
77954358960
-
Mysterious Oligomerization of the Amyloidogenic Proteins
-
Uversky, V. N. Mysterious Oligomerization of the Amyloidogenic Proteins FEBS J. 2010, 277, 2940-2953
-
(2010)
FEBS J.
, vol.277
, pp. 2940-2953
-
-
Uversky, V.N.1
-
20
-
-
3242735504
-
An Amyloid-Forming Segment of β 2-Microglobulin Suggests a Molecular Model for the Fibril
-
Ivanova, M. I.; Sawaya, M. R.; Gingery, M.; Attinger, A.; Eisenberg, D. An Amyloid-Forming Segment of β 2-Microglobulin Suggests a Molecular Model for the Fibril Proc. Natl. Acad. Sci. U.S.A. 2004, 101, 10584-10589
-
(2004)
Proc. Natl. Acad. Sci. U.S.A.
, vol.101
, pp. 10584-10589
-
-
Ivanova, M.I.1
Sawaya, M.R.2
Gingery, M.3
Attinger, A.4
Eisenberg, D.5
-
21
-
-
0033849738
-
Review: History of the Amyloid Fibril
-
Sipe, J. D.; Cohen, A. S. Review: History of the Amyloid Fibril J. Struct. Biol. 2000, 130, 88-98
-
(2000)
J. Struct. Biol.
, vol.130
, pp. 88-98
-
-
Sipe, J.D.1
Cohen, A.S.2
-
22
-
-
33645240208
-
A Systematic Screen of β(2)-Microglobulin and Insulin for Amyloid-Like Segments
-
Ivanova, M. I.; Thompson, M. J.; Eisenberg, D. A Systematic Screen of β(2)-Microglobulin and Insulin for Amyloid-Like Segments Proc. Natl. Acad. Sci. U.S.A. 2006, 103, 4079-4082
-
(2006)
Proc. Natl. Acad. Sci. U.S.A.
, vol.103
, pp. 4079-4082
-
-
Ivanova, M.I.1
Thompson, M.J.2
Eisenberg, D.3
-
23
-
-
33645995764
-
Recent Atomic Models of Amyloid Fibril Structure
-
Nelson, R.; Eisenberg, D. Recent Atomic Models of Amyloid Fibril Structure Curr. Opin. Struc. Biol. 2006, 16, 260-265
-
(2006)
Curr. Opin. Struc. Biol.
, vol.16
, pp. 260-265
-
-
Nelson, R.1
Eisenberg, D.2
-
24
-
-
33645238380
-
The 3D Profile Method for Identifying Fibril-Forming Segments of Proteins
-
Thompson, M. J.; Sievers, S. A.; Karanicolas, J.; Ivanova, M. I.; Baker, D.; Eisenberg, D. The 3D Profile Method for Identifying Fibril-Forming Segments of Proteins Proc. Natl. Acad. Sci. U.S.A. 2006, 103, 4074-4078
-
(2006)
Proc. Natl. Acad. Sci. U.S.A.
, vol.103
, pp. 4074-4078
-
-
Thompson, M.J.1
Sievers, S.A.2
Karanicolas, J.3
Ivanova, M.I.4
Baker, D.5
Eisenberg, D.6
-
25
-
-
77649240855
-
Identifying the Amylome, Proteins Capable of Forming Amyloid-Like Fibrils
-
Goldschmidt, L.; Teng, P. K.; Riek, R.; Eisenberg, D. Identifying the Amylome, Proteins Capable of Forming Amyloid-Like Fibrils Proc. Natl. Acad. Sci. U.S.A. 2010, 107, 3487-3492
-
(2010)
Proc. Natl. Acad. Sci. U.S.A.
, vol.107
, pp. 3487-3492
-
-
Goldschmidt, L.1
Teng, P.K.2
Riek, R.3
Eisenberg, D.4
-
26
-
-
83455171054
-
Secondary Nucleating Sequences Affect Kinetics and Thermodynamics of Tau Aggregation
-
Moore, C. L.; Huang, M. H.; Robbennolt, S. A.; Voss, K. R.; Combs, B.; Gamblin, T. C.; Goux, W. J. Secondary Nucleating Sequences Affect Kinetics and Thermodynamics of Tau Aggregation Biochemistry 2011, 50, 10876-10886
-
(2011)
Biochemistry
, vol.50
, pp. 10876-10886
-
-
Moore, C.L.1
Huang, M.H.2
Robbennolt, S.A.3
Voss, K.R.4
Combs, B.5
Gamblin, T.C.6
Goux, W.J.7
-
27
-
-
79955770935
-
Mapping the Conformational Dynamics and Pathways of Spontaneous Steric Zipper Peptide Oligomerization
-
Matthes, D.; Gapsys, V.; Daebel, V.; de Groot, B. L. Mapping the Conformational Dynamics and Pathways of Spontaneous Steric Zipper Peptide Oligomerization PLoS One 2011, 6, e19129
-
(2011)
PLoS One
, vol.6
, pp. 19129
-
-
Matthes, D.1
Gapsys, V.2
Daebel, V.3
De Groot, B.L.4
-
28
-
-
84865376943
-
Dynamical Properties of Steric Zipper Polymorphs Formed by a IAPP-Derived Peptide
-
Stanzione, F.; De Simone, A.; Esposito, L.; Vitagliano, L. Dynamical Properties of Steric Zipper Polymorphs Formed by a IAPP-Derived Peptide Protein Pept. Lett. 2012, 19, 846-851
-
(2012)
Protein Pept. Lett.
, vol.19
, pp. 846-851
-
-
Stanzione, F.1
De Simone, A.2
Esposito, L.3
Vitagliano, L.4
-
29
-
-
70349658765
-
Thermodynamic Selection of Steric Zipper Patterns in the Amyloid Cross-β Spine
-
Park, J.; Kahng, B.; Hwang, W. Thermodynamic Selection of Steric Zipper Patterns in the Amyloid Cross-β Spine PLoS Comput. Biol. 2009, 5, e1000492
-
(2009)
PLoS Comput. Biol.
, vol.5
, pp. 1000492
-
-
Park, J.1
Kahng, B.2
Hwang, W.3
-
30
-
-
84863989280
-
Driving Forces and Structural Determinants of Steric Zipper Peptide Oligomer Formation Elucidated by Atomistic Simulations
-
Matthes, D.; Gapsys, V.; de Groot, B. L. Driving Forces and Structural Determinants of Steric Zipper Peptide Oligomer Formation Elucidated by Atomistic Simulations J. Mol. Biol. 2012, 421, 390-416
-
(2012)
J. Mol. Biol.
, vol.421
, pp. 390-416
-
-
Matthes, D.1
Gapsys, V.2
De Groot, B.L.3
-
31
-
-
84865663663
-
β-Sheet Core of Tau Paired Helical Filaments Revealed by Solid-State NMR
-
Daebel, V.; Chinnathambi, S.; Biernat, J.; Schwalbe, M.; Habenstein, B.; Loquet, A.; Akoury, E.; Tepper, K.; Muller, H.; Baldus, M.; Griesinger, C.; Zweckstetter, M.; Mandelkow, E.; Vijayan, V.; Lange, A. β-Sheet Core of Tau Paired Helical Filaments Revealed by Solid-State NMR J. Am. Chem. Soc. 2012, 134, 13982-13989
-
(2012)
J. Am. Chem. Soc.
, vol.134
, pp. 13982-13989
-
-
Daebel, V.1
Chinnathambi, S.2
Biernat, J.3
Schwalbe, M.4
Habenstein, B.5
Loquet, A.6
Akoury, E.7
Tepper, K.8
Muller, H.9
Baldus, M.10
Griesinger, C.11
Zweckstetter, M.12
Mandelkow, E.13
Vijayan, V.14
Lange, A.15
-
32
-
-
42649108674
-
Steric Zipper of the Amyloid Fibrils Formed by Residues 109-122 of the Syrian Hamster Prion Protein
-
Lee, S. W.; Mou, Y.; Lin, S. Y.; Chou, F. C.; Tseng, W. H.; Chen, C. H.; Lu, C. Y.; Yu, S. S.; Chan, J. C. Steric Zipper of the Amyloid Fibrils Formed by Residues 109-122 of the Syrian Hamster Prion Protein J. Mol. Biol. 2008, 378, 1142-1154
-
(2008)
J. Mol. Biol.
, vol.378
, pp. 1142-1154
-
-
Lee, S.W.1
Mou, Y.2
Lin, S.Y.3
Chou, F.C.4
Tseng, W.H.5
Chen, C.H.6
Lu, C.Y.7
Yu, S.S.8
Chan, J.C.9
-
33
-
-
84861332104
-
Unique Example of Amyloid Aggregates Stabilized by Main Chain H-Bond Instead of the Steric Zipper: Molecular Dynamics Study of the Amyloidogenic Segment of Amylin Wild-Type and Mutants
-
Berhanu, W. M.; Masunov, A. E. Unique Example of Amyloid Aggregates Stabilized by Main Chain H-Bond Instead of the Steric Zipper: Molecular Dynamics Study of the Amyloidogenic Segment of Amylin Wild-Type and Mutants J. Mol. Model. 2012, 18, 891-903
-
(2012)
J. Mol. Model.
, vol.18
, pp. 891-903
-
-
Berhanu, W.M.1
Masunov, A.E.2
-
34
-
-
68849107584
-
Thermodynamic Description of Polymorphism in Q- and N-Rich Peptide Aggregates Revealed by Atomistic Simulation
-
Berryman, J. T.; Radford, S. E.; Harris, S. A. Thermodynamic Description of Polymorphism in Q- and N-Rich Peptide Aggregates Revealed by Atomistic Simulation Biophys. J. 2009, 97, 1-11
-
(2009)
Biophys. J.
, vol.97
, pp. 1-11
-
-
Berryman, J.T.1
Radford, S.E.2
Harris, S.A.3
-
35
-
-
33746765060
-
Structural Stability and Dynamics of an Amyloid-Forming Peptide GNNQQNY from the Yeast Prion Sup-35
-
Zheng, J.; Ma, B.; Tsai, C. J.; Nussinov, R. Structural Stability and Dynamics of an Amyloid-Forming Peptide GNNQQNY from the Yeast Prion Sup-35 Biophys. J. 2006, 91, 824-833
-
(2006)
Biophys. J.
, vol.91
, pp. 824-833
-
-
Zheng, J.1
Ma, B.2
Tsai, C.J.3
Nussinov, R.4
-
36
-
-
33845978790
-
Insight into the Structure of Amyloid Fibrils from the Analysis of Globular Proteins
-
Trovato, A.; Chiti, F.; Maritan, A.; Seno, F. Insight into the Structure of Amyloid Fibrils from the Analysis of Globular Proteins Plos Comput. Biol. 2006, 2, 1608-1618
-
(2006)
Plos Comput. Biol.
, vol.2
, pp. 1608-1618
-
-
Trovato, A.1
Chiti, F.2
Maritan, A.3
Seno, F.4
-
37
-
-
36248964819
-
The Pasta Server for Protein Aggregation Prediction
-
Trovato, A.; Seno, F.; Tosatto, S. C. E. The Pasta Server for Protein Aggregation Prediction Protein Eng., Des. Sel. 2007, 20, 521-523
-
(2007)
Protein Eng., Des. Sel.
, vol.20
, pp. 521-523
-
-
Trovato, A.1
Seno, F.2
Tosatto, S.C.E.3
-
38
-
-
20444403757
-
Prediction of "aggregation-Prone" and "aggregation- Susceptible" Regions in Proteins Associated with Neurodegenerative Diseases
-
Pawar, A. P.; Dubay, K. F.; Zurdo, J.; Chiti, F.; Vendruscolo, M.; Dobson, C. M. Prediction of "Aggregation-Prone" and "Aggregation-Susceptible" Regions in Proteins Associated with Neurodegenerative Diseases J. Mol. Biol. 2005, 350, 379-392
-
(2005)
J. Mol. Biol.
, vol.350
, pp. 379-392
-
-
Pawar, A.P.1
Dubay, K.F.2
Zurdo, J.3
Chiti, F.4
Vendruscolo, M.5
Dobson, C.M.6
-
39
-
-
44949219079
-
Prediction of Aggregation-Prone Regions in Structured Proteins
-
Tartaglia, G. G.; Pawar, A. P.; Campioni, S.; Dobson, C. M.; Chiti, F.; Vendruscolo, M. Prediction of Aggregation-Prone Regions in Structured Proteins J. Mol. Biol. 2008, 380, 425-436
-
(2008)
J. Mol. Biol.
, vol.380
, pp. 425-436
-
-
Tartaglia, G.G.1
Pawar, A.P.2
Campioni, S.3
Dobson, C.M.4
Chiti, F.5
Vendruscolo, M.6
-
40
-
-
77049104900
-
Characterizing the Assembly of the Sup35 Yeast Prion Fragment, GNNQQNY: Structural Changes Accompany a Fiber-to-Crystal Switch
-
Marshall, K. E.; Hicks, M. R.; Williams, T. L.; Hoffmann, S. V.; Rodger, A.; Dafforn, T. R.; Serpell, L. C. Characterizing the Assembly of the Sup35 Yeast Prion Fragment, GNNQQNY: Structural Changes Accompany a Fiber-to-Crystal Switch Biophys. J. 2010, 98, 330-338
-
(2010)
Biophys. J.
, vol.98
, pp. 330-338
-
-
Marshall, K.E.1
Hicks, M.R.2
Williams, T.L.3
Hoffmann, S.V.4
Rodger, A.5
Dafforn, T.R.6
Serpell, L.C.7
-
42
-
-
80054892557
-
Structural Stability from Solution to the Gas Phase: Native Solution Structure of Ubiquitin Survives Analysis in a Solvent-Free Ion Mobility-Mass Spectrometry Environment
-
Wyttenbach, T.; Bowers, M. T. Structural Stability from Solution to the Gas Phase: Native Solution Structure of Ubiquitin Survives Analysis in a Solvent-Free Ion Mobility-Mass Spectrometry Environment J. Phys. Chem. B 2011, 115, 12266-12275
-
(2011)
J. Phys. Chem. B
, vol.115
, pp. 12266-12275
-
-
Wyttenbach, T.1
Bowers, M.T.2
-
43
-
-
67849106670
-
Amyloid-β Protein Oligomerization and the Importance of Tetramers and Dodecamers in the Aetiology of Alzheimer's Disease
-
Bernstein, S. L.; Dupuis, N. F.; Lazo, N. D.; Wyttenbach, T.; Condron, M. M.; Bitan, G.; Teplow, D. B.; Shea, J.-E.; Ruotolo, B. T.; Robinson, C. V.; Bowers, M. T. Amyloid-β Protein Oligomerization and the Importance of Tetramers and Dodecamers in the Aetiology of Alzheimer's Disease Nat. Chem. 2009, 1, 326-331
-
(2009)
Nat. Chem.
, vol.1
, pp. 326-331
-
-
Bernstein, S.L.1
Dupuis, N.F.2
Lazo, N.D.3
Wyttenbach, T.4
Condron, M.M.5
Bitan, G.6
Teplow, D.B.7
Shea, J.-E.8
Ruotolo, B.T.9
Robinson, C.V.10
Bowers, M.T.11
-
44
-
-
70349730066
-
Higher Resolution, Ion Mobility Mass Spectrometer
-
Kemper, P. R.; Dupuis, N. F.; Bowers, M. T.; New, A. Higher Resolution, Ion Mobility Mass Spectrometer Int. J. Mass. Spectrom. 2009, 287, 46-57
-
(2009)
Int. J. Mass. Spectrom.
, vol.287
, pp. 46-57
-
-
Kemper, P.R.1
Dupuis, N.F.2
Bowers, M.T.3
New, A.4
-
47
-
-
4944240546
-
The Determination of Cis-Trans Conformations in Tetrahedral p -Phenylene Vinylene Oligomers
-
Bushnell, J. E.; Kemper, P. R.; Bazan, G. C.; Bowers, M. T. The Determination of Cis-Trans Conformations in Tetrahedral p -Phenylene Vinylene Oligomers J. Phys. Chem. A 2004, 108, 7730-7735
-
(2004)
J. Phys. Chem. A
, vol.108
, pp. 7730-7735
-
-
Bushnell, J.E.1
Kemper, P.R.2
Bazan, G.C.3
Bowers, M.T.4
-
48
-
-
46249092554
-
Gromacs 4: Algorithms for Highly Efficient, Load-Balanced, and Scalable Molecular Simulation
-
Hess, B.; Kutzner, C.; Spoel, D. v. d.; Lindahl, E. Gromacs 4: Algorithms for Highly Efficient, Load-Balanced, and Scalable Molecular Simulation J. Chem. Theory Comput. 2008, 4, 435-437
-
(2008)
J. Chem. Theory Comput.
, vol.4
, pp. 435-437
-
-
Hess, B.1
Kutzner, C.2
Spoel, D.V.D.3
Lindahl, E.4
-
49
-
-
27344454932
-
Gromacs: Fast, Flexible, and Free
-
Spoel, D. V. D.; Lindahl, E.; Hess, B.; Groenhof, G.; Mark, A. E.; Berendsen, H. J. C. Gromacs: Fast, Flexible, and Free J. Comput. Chem. 2005, 26, 1701-1718
-
(2005)
J. Comput. Chem.
, vol.26
, pp. 1701-1718
-
-
Spoel, D.V.D.1
Lindahl, E.2
Hess, B.3
Groenhof, G.4
Mark, A.E.5
Berendsen, H.J.C.6
-
50
-
-
56349105206
-
Opls-2002: A New Version of the OPLS-AA Force Field
-
Damm, W.; Halgren, T. A.; Murphy, R. B.; Smondyrev, A. M.; Friesner, R. A.; Jorgensen, W. L. Opls-2002: A New Version of the OPLS-AA Force Field Abstr. Pap. Am. Chem. Soc. 2002, 224, U471-U471
-
(2002)
Abstr. Pap. Am. Chem. Soc.
, vol.224
-
-
Damm, W.1
Halgren, T.A.2
Murphy, R.B.3
Smondyrev, A.M.4
Friesner, R.A.5
Jorgensen, W.L.6
-
51
-
-
84894670314
-
Extending the OPLS-AA Force Field for Ligand Functionality
-
Halgren, T. A.; Murphy, R. B.; Jorgensen, W. L.; Friesner, R. A. Extending the OPLS-AA Force Field for Ligand Functionality Abstr. Pap. Am. Chem. Soc. 2000, 220, U277-U277
-
(2000)
Abstr. Pap. Am. Chem. Soc.
, vol.220
-
-
Halgren, T.A.1
Murphy, R.B.2
Jorgensen, W.L.3
Friesner, R.A.4
-
52
-
-
0029912748
-
Development and Testing of the OPLS All-Atom Force Field on Conformational Energetics and Properties of Organic Liquids
-
Jorgensen, W. L.; Maxwell, D. S.; TiradoRives, J. Development and Testing of the OPLS All-Atom Force Field on Conformational Energetics and Properties of Organic Liquids J. Am. Chem. Soc. 1996, 118, 11225-11236
-
(1996)
J. Am. Chem. Soc.
, vol.118
, pp. 11225-11236
-
-
Jorgensen, W.L.1
Maxwell, D.S.2
Tiradorives, J.3
-
53
-
-
0004016501
-
Comparison of Simple Potential Functions for Simulating Liquid Water
-
Jorgensen, W. L.; Chandrasekhar, J.; Madura, J. D.; Impey, R. W.; Klein, M. L. Comparison of Simple Potential Functions for Simulating Liquid Water J. Chem. Phys. 1983, 79, 926-935
-
(1983)
J. Chem. Phys.
, vol.79
, pp. 926-935
-
-
Jorgensen, W.L.1
Chandrasekhar, J.2
Madura, J.D.3
Impey, R.W.4
Klein, M.L.5
-
54
-
-
0000388705
-
Lincs: A Linear Constraint Solver for Molecular Simulations
-
Hess, B.; Bekker, H.; Berendsen, H. J. C.; Fraaije, J. G. E. M. Lincs: A Linear Constraint Solver for Molecular Simulations J. Comput. Chem. 1997, 18, 1463-1472
-
(1997)
J. Comput. Chem.
, vol.18
, pp. 1463-1472
-
-
Hess, B.1
Bekker, H.2
Berendsen, H.J.C.3
Fraaije, J.G.E.M.4
-
55
-
-
84986440341
-
Settle - An Analytical Version of the Shake and Rattle Algorithm for Rigid Water Models
-
Miyamoto, S.; Kollman, P. A. Settle-an Analytical Version of the Shake and Rattle Algorithm for Rigid Water Models J. Comput. Chem. 1992, 13, 952-962
-
(1992)
J. Comput. Chem.
, vol.13
, pp. 952-962
-
-
Miyamoto, S.1
Kollman, P.A.2
-
56
-
-
33846823909
-
Particle Mesh Ewald: An N·Log(N) Method for Ewald Sums in Large Systems
-
Darden, T.; York, D.; Pedersen, L. Particle Mesh Ewald: An N·Log(N) Method for Ewald Sums in Large Systems J. Chem. Phys. 1993, 98, 10089-10093
-
(1993)
J. Chem. Phys.
, vol.98
, pp. 10089-10093
-
-
Darden, T.1
York, D.2
Pedersen, L.3
-
57
-
-
33645961739
-
Particle Mesh Ewald Method
-
Essmann, U.; Perera, L.; Berkowitz, M. L.; Darden, T.; Lee, H.; Pedersen, L. G.; Smooth, A. Particle Mesh Ewald Method J. Chem. Phys. 1995, 103, 8577-8593
-
(1995)
J. Chem. Phys.
, vol.103
, pp. 8577-8593
-
-
Essmann, U.1
Perera, L.2
Berkowitz, M.L.3
Darden, T.4
Lee, H.5
Pedersen, L.G.6
Smooth, A.7
-
58
-
-
36549093652
-
The Nose-Hoover Thermostat
-
Evans, D. J.; Holian, B. L. The Nose-Hoover Thermostat J. Chem. Phys. 1985, 83, 4069-4074
-
(1985)
J. Chem. Phys.
, vol.83
, pp. 4069-4074
-
-
Evans, D.J.1
Holian, B.L.2
-
59
-
-
61949163833
-
Factors That Affect the Degree of Twist in β-Sheet Structures: A Molecular Dynamics Simulation Study of a Cross-Beta Filament of the GNNQQNY Peptide
-
Periole, X.; Rampioni, A.; Vendruscolo, M.; Mark, A. E. Factors That Affect the Degree of Twist in β-Sheet Structures: A Molecular Dynamics Simulation Study of a Cross-Beta Filament of the GNNQQNY Peptide J. Phys. Chem. B 2009, 113, 1728-1737
-
(2009)
J. Phys. Chem. B
, vol.113
, pp. 1728-1737
-
-
Periole, X.1
Rampioni, A.2
Vendruscolo, M.3
Mark, A.E.4
-
60
-
-
19444380574
-
Protein Misfolding and Amyloid Formation for the Peptide GNNQQNY from Yeast Prion Protein Sup35: Simulation by Reaction Path Annealing
-
Lipfert, J.; Franklin, J.; Wu, F.; Doniach, S. Protein Misfolding and Amyloid Formation for the Peptide GNNQQNY from Yeast Prion Protein Sup35: Simulation by Reaction Path Annealing J. Mol. Biol. 2005, 349, 648-658
-
(2005)
J. Mol. Biol.
, vol.349
, pp. 648-658
-
-
Lipfert, J.1
Franklin, J.2
Wu, F.3
Doniach, S.4
-
61
-
-
56349091416
-
Stability of Single Sheet GNNQQNY Aggregates Analyzed by Replica Exchange Molecular Dynamics: Antiparallel Versus Parallel Association
-
Vitagliano, L.; Esposito, L.; Pedone, C.; De Simone, A. Stability of Single Sheet GNNQQNY Aggregates Analyzed by Replica Exchange Molecular Dynamics: Antiparallel Versus Parallel Association Biochem. Biophys. Res. Commun. 2008, 377, 1036-1041
-
(2008)
Biochem. Biophys. Res. Commun.
, vol.377
, pp. 1036-1041
-
-
Vitagliano, L.1
Esposito, L.2
Pedone, C.3
De Simone, A.4
-
62
-
-
50349099883
-
Insights into Stability and Toxicity of Amyloid-Like Oligomers by Replica Exchange Molecular Dynamics Analyses
-
De Simone, A.; Esposito, L.; Pedone, C.; Vitagliano, L. Insights into Stability and Toxicity of Amyloid-Like Oligomers by Replica Exchange Molecular Dynamics Analyses Biophys. J. 2008, 95, 1965-1973
-
(2008)
Biophys. J.
, vol.95
, pp. 1965-1973
-
-
De Simone, A.1
Esposito, L.2
Pedone, C.3
Vitagliano, L.4
-
63
-
-
37549055108
-
Thermodynamics and Kinetics of Aggregation for the GNNQQNY Peptide
-
Strodel, B.; Whittleston, C. S.; Wales, D. J. Thermodynamics and Kinetics of Aggregation for the GNNQQNY Peptide J. Am. Chem. Soc. 2007, 129, 16005-16014
-
(2007)
J. Am. Chem. Soc.
, vol.129
, pp. 16005-16014
-
-
Strodel, B.1
Whittleston, C.S.2
Wales, D.J.3
-
64
-
-
77949612059
-
GNNQQNY-Investigation of Early Steps during Amyloid Formation
-
Reddy, A. S.; Chopra, M.; de Pablo, J. J. GNNQQNY-Investigation of Early Steps During Amyloid Formation Biophys. J. 2010, 98, 1038-1045
-
(2010)
Biophys. J.
, vol.98
, pp. 1038-1045
-
-
Reddy, A.S.1
Chopra, M.2
De Pablo, J.J.3
-
65
-
-
84863032716
-
A Variational Model for Oligomer-Formation Process of GNNQQNY Peptide from Yeast Prion Protein Sup35
-
Qi, X. H.; Hong, L.; Zhang, Y. A Variational Model for Oligomer-Formation Process of GNNQQNY Peptide from Yeast Prion Protein Sup35 Biophys. J. 2012, 102, 597-605
-
(2012)
Biophys. J.
, vol.102
, pp. 597-605
-
-
Qi, X.H.1
Hong, L.2
Zhang, Y.3
-
66
-
-
80052786276
-
Structural Complexity of a Composite Amyloid Fibril
-
Lewandowski, J. R.; van der Wel, P. C. A.; Rigney, M.; Grigorieff, N.; Griffin, R. G. Structural Complexity of a Composite Amyloid Fibril J. Am. Chem. Soc. 2011, 133, 14686-14698
-
(2011)
J. Am. Chem. Soc.
, vol.133
, pp. 14686-14698
-
-
Lewandowski, J.R.1
Van Der Wel, P.C.A.2
Rigney, M.3
Grigorieff, N.4
Griffin, R.G.5
-
67
-
-
84867320649
-
Twisting Transition between Crystalline and Fibrillar Phases of Aggregated Peptides
-
Knowles, T. P. J.; De Simone, A.; Fitzpatrick, A. W.; Baldwin, A.; Meehan, S.; Rajah, L.; Vendruscolo, M.; Welland, M. E.; Dobson, C. M.; Terentjev, E. M., Twisting Transition between Crystalline and Fibrillar Phases of Aggregated Peptides. Phys. Rev. Lett. 2012, 109.
-
(2012)
Phys. Rev. Lett.
, vol.109
-
-
Knowles, T.P.J.1
De Simone, A.2
Fitzpatrick, A.W.3
Baldwin, A.4
Meehan, S.5
Rajah, L.6
Vendruscolo, M.7
Welland, M.E.8
Dobson, C.M.9
Terentjev, E.M.10
-
68
-
-
0033637078
-
Ultrastructural Organization of Amyloid Fibrils by Atomic Force Microscopy
-
Chamberlain, A. K.; MacPhee, C. E.; Zurdo, J.; Morozova-Roche, L. A.; Hill, H. A. O.; Dobson, C. M.; Davis, J. J. Ultrastructural Organization of Amyloid Fibrils by Atomic Force Microscopy Biophys. J. 2000, 79, 3282-3293
-
(2000)
Biophys. J.
, vol.79
, pp. 3282-3293
-
-
Chamberlain, A.K.1
Macphee, C.E.2
Zurdo, J.3
Morozova-Roche, L.A.4
Hill, H.A.O.5
Dobson, C.M.6
Davis, J.J.7
-
69
-
-
79952193876
-
Assessing Mutant Huntingtin Fragment and Polyglutamine Aggregation by Atomic Force Microscopy
-
Burke, K. A.; Godbey, J.; Legleiter, J. Assessing Mutant Huntingtin Fragment and Polyglutamine Aggregation by Atomic Force Microscopy Methods 2011, 53, 275-284
-
(2011)
Methods
, vol.53
, pp. 275-284
-
-
Burke, K.A.1
Godbey, J.2
Legleiter, J.3
-
70
-
-
75149194975
-
Sequence Periodicity and Secondary Structure Propensity in Model Proteins
-
Bellesia, G.; Jewett, A. I.; Shea, J. E. Sequence Periodicity and Secondary Structure Propensity in Model Proteins Protein Sci. 2010, 19, 141-154
-
(2010)
Protein Sci.
, vol.19
, pp. 141-154
-
-
Bellesia, G.1
Jewett, A.I.2
Shea, J.E.3
-
71
-
-
84878078985
-
Initiation of Assembly of Tau(273-284) and Its Δk280 Mutant: An Experimental and Computational Study
-
Larini, L.; Gessel, M. M.; Lapointe, N. E.; Do, T. D.; Bowers, M. T.; Feinstein, S. C.; Shea, J. E. Initiation of Assembly of Tau(273-284) and Its ΔK280 Mutant: An Experimental and Computational Study Phys. Chem. Chem. Phys. 2013, 15, 8916-8928
-
(2013)
Phys. Chem. Chem. Phys.
, vol.15
, pp. 8916-8928
-
-
Larini, L.1
Gessel, M.M.2
Lapointe, N.E.3
Do, T.D.4
Bowers, M.T.5
Feinstein, S.C.6
Shea, J.E.7
-
72
-
-
0037059063
-
De Novo Designed Peptide-Based Amyloid Fibrils
-
de la Paz, M. L.; Goldie, K.; Zurdo, J.; Lacroix, E.; Dobson, C. M.; Hoenger, A.; Serrano, L. De Novo Designed Peptide-Based Amyloid Fibrils Proc. Natl. Acad. Sci. U.S.A. 2002, 99, 16052-16057
-
(2002)
Proc. Natl. Acad. Sci. U.S.A.
, vol.99
, pp. 16052-16057
-
-
De La Paz, M.L.1
Goldie, K.2
Zurdo, J.3
Lacroix, E.4
Dobson, C.M.5
Hoenger, A.6
Serrano, L.7
-
73
-
-
84865957943
-
Distinguishing Crystal-Like Amyloid Fibrils and Glass-Like Amorphous Aggregates from Their Kinetics of Formation
-
Yoshimura, Y.; Lin, Y. X.; Yagi, H.; Lee, Y. H.; Kitayama, H.; Sakurai, K.; So, M.; Ogi, H.; Naiki, H.; Goto, Y. Distinguishing Crystal-Like Amyloid Fibrils and Glass-Like Amorphous Aggregates from Their Kinetics of Formation Proc. Natl. Acad. Sci. U.S.A. 2012, 109, 14446-14451
-
(2012)
Proc. Natl. Acad. Sci. U.S.A.
, vol.109
, pp. 14446-14451
-
-
Yoshimura, Y.1
Lin, Y.X.2
Yagi, H.3
Lee, Y.H.4
Kitayama, H.5
Sakurai, K.6
So, M.7
Ogi, H.8
Naiki, H.9
Goto, Y.10
|