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Volumn 280, Issue 15, 2013, Pages 3508-3518

The expanding role of PARPs in the establishment and maintenance of heterochromatin

Author keywords

ARTD; centromeres; heterochromatin; pericentric heterochromatin; poly(ADP ribose) polymerase; rDNA; telomeres; X chromosome inactivation

Indexed keywords

DNA; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 2; RIBOSOME RNA;

EID: 84880330797     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/febs.12368     Document Type: Review
Times cited : (45)

References (85)
  • 2
    • 84862758175 scopus 로고    scopus 로고
    • New insights into the molecular and cellular functions of poly(ADP-ribose) and PARPs
    • Gibson BA, &, Kraus WL, (2012) New insights into the molecular and cellular functions of poly(ADP-ribose) and PARPs. Nat Rev Mol Cell Biol 13, 411-424.
    • (2012) Nat Rev Mol Cell Biol , vol.13 , pp. 411-424
    • Gibson, B.A.1    Kraus, W.L.2
  • 3
    • 84886719040 scopus 로고    scopus 로고
    • PARP-1 and gene regulation: Progress and puzzles
    • doi: 10.1016/j.mam.2013.01.005
    • Kraus L, &, Hottiger MO, (2013) PARP-1 and gene regulation: progress and puzzles. Mol Aspects Med doi: 10.1016/j.mam.2013.01.005.
    • (2013) Mol Aspects Med
    • Kraus, L.1    Hottiger, M.O.2
  • 4
    • 36148986455 scopus 로고    scopus 로고
    • Nucleosomal core histones mediate dynamic regulation of poly(ADP-ribose) polymerase 1 protein binding to chromatin and induction of its enzymatic activity
    • Pinnola A, Naumova N, Shah M, &, Tulin AV, (2007) Nucleosomal core histones mediate dynamic regulation of poly(ADP-ribose) polymerase 1 protein binding to chromatin and induction of its enzymatic activity. J Biol Chem 282, 32511-32519.
    • (2007) J Biol Chem , vol.282 , pp. 32511-32519
    • Pinnola, A.1    Naumova, N.2    Shah, M.3    Tulin, A.V.4
  • 7
  • 9
    • 33745375693 scopus 로고    scopus 로고
    • PARP1 is a TRF2-associated poly(ADP-ribose)polymerase and protects eroded telomeres
    • Gomez M, Wu J, Schreiber V, Dunlap J, Dantzer F, Wang Y, &, Liu Y, (2006) PARP1 is a TRF2-associated poly(ADP-ribose)polymerase and protects eroded telomeres. Mol Biol Cell 17, 1686-1696.
    • (2006) Mol Biol Cell , vol.17 , pp. 1686-1696
    • Gomez, M.1    Wu, J.2    Schreiber, V.3    Dunlap, J.4    Dantzer, F.5    Wang, Y.6    Liu, Y.7
  • 11
    • 55549119952 scopus 로고    scopus 로고
    • The histone subcode: Poly(ADP-ribose) polymerase-1 (Parp-1) and Parp-2 control cell differentiation by regulating the transcriptional intermediary factor TIF1β and the heterochromatin protein HP1α
    • Quenet D, Gasser V, Fouillen L, Cammas F, Sanglier-Cianferani S, Losson R, &, Dantzer F, (2008) The histone subcode: poly(ADP-ribose) polymerase-1 (Parp-1) and Parp-2 control cell differentiation by regulating the transcriptional intermediary factor TIF1β and the heterochromatin protein HP1α. FASEB J 22, 3853-3865.
    • (2008) FASEB J , vol.22 , pp. 3853-3865
    • Quenet, D.1    Gasser, V.2    Fouillen, L.3    Cammas, F.4    Sanglier-Cianferani, S.5    Losson, R.6    Dantzer, F.7
  • 12
    • 84859051225 scopus 로고    scopus 로고
    • Inheritance of silent rDNA chromatin is mediated by PARP1 via noncoding RNA
    • Guetg C, Scheifele F, Rosenthal F, Hottiger MO, &, Santoro R, (2012) Inheritance of silent rDNA chromatin is mediated by PARP1 via noncoding RNA. Mol Cell 45, 790-800.
    • (2012) Mol Cell , vol.45 , pp. 790-800
    • Guetg, C.1    Scheifele, F.2    Rosenthal, F.3    Hottiger, M.O.4    Santoro, R.5
  • 13
    • 77950870459 scopus 로고    scopus 로고
    • Uncoupling of the transactivation and transrepression functions of PARP1 protein
    • Kotova E, Jarnik M, &, Tulin AV, (2010) Uncoupling of the transactivation and transrepression functions of PARP1 protein. Proc Natl Acad Sci USA 107, 6406-6411.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 6406-6411
    • Kotova, E.1    Jarnik, M.2    Tulin, A.V.3
  • 14
    • 0037102454 scopus 로고    scopus 로고
    • The Drosophila heterochromatic gene encoding poly(ADP-ribose) polymerase (PARP) is required to modulate chromatin structure during development
    • Tulin A, Stewart D, &, Spradling AC, (2002) The Drosophila heterochromatic gene encoding poly(ADP-ribose) polymerase (PARP) is required to modulate chromatin structure during development. Genes Dev 16, 2108-2119.
    • (2002) Genes Dev , vol.16 , pp. 2108-2119
    • Tulin, A.1    Stewart, D.2    Spradling, A.C.3
  • 15
    • 77956648852 scopus 로고    scopus 로고
    • The roles of PARP1 in gene control and cell differentiation
    • Ji Y, &, Tulin AV, (2010) The roles of PARP1 in gene control and cell differentiation. Curr Opin Genet Dev 20, 512-518.
    • (2010) Curr Opin Genet Dev , vol.20 , pp. 512-518
    • Ji, Y.1    Tulin, A.V.2
  • 16
    • 0024406764 scopus 로고
    • The effect of poly(ADP-ribosyl)ation on native and H1-depleted chromatin. A role of poly(ADP-ribosyl)ation on core nucleosome structure
    • Huletsky A, De Murcia G, Muller S, Hengartner M, Menard L, Lamarre D, &, Poirier GG, (1989) The effect of poly(ADP-ribosyl)ation on native and H1-depleted chromatin. A role of poly(ADP-ribosyl)ation on core nucleosome structure. J Biol Chem 264, 8878-8886.
    • (1989) J Biol Chem , vol.264 , pp. 8878-8886
    • Huletsky, A.1    De Murcia, G.2    Muller, S.3    Hengartner, M.4    Menard, L.5    Lamarre, D.6    Poirier, G.G.7
  • 17
    • 10944227347 scopus 로고    scopus 로고
    • +-dependent modulation of chromatin structure and transcription by nucleosome binding properties of PARP-1
    • +-dependent modulation of chromatin structure and transcription by nucleosome binding properties of PARP-1. Cell 119, 803-814.
    • (2004) Cell , vol.119 , pp. 803-814
    • Kim, M.Y.1    Mauro, S.2    Gevry, N.3    Lis, J.T.4    Kraus, W.L.5
  • 18
    • 0023117437 scopus 로고
    • Release of core DNA from nucleosomal core particles following (ADP-ribose)n-modification in vitro
    • Mathis G, &, Althaus FR, (1987) Release of core DNA from nucleosomal core particles following (ADP-ribose)n-modification in vitro. Biochem Biophys Res Commun 143, 1049-1054.
    • (1987) Biochem Biophys Res Commun , vol.143 , pp. 1049-1054
    • Mathis, G.1    Althaus, F.R.2
  • 20
    • 35648955118 scopus 로고    scopus 로고
    • The DNA binding and catalytic domains of poly(ADP-ribose) polymerase 1 cooperate in the regulation of chromatin structure and transcription
    • Wacker DA, Ruhl DD, Balagamwala EH, Hope KM, Zhang T, &, Kraus WL, (2007) The DNA binding and catalytic domains of poly(ADP-ribose) polymerase 1 cooperate in the regulation of chromatin structure and transcription. Mol Cell Biol 27, 7475-7485.
    • (2007) Mol Cell Biol , vol.27 , pp. 7475-7485
    • Wacker, D.A.1    Ruhl, D.D.2    Balagamwala, E.H.3    Hope, K.M.4    Zhang, T.5    Kraus, W.L.6
  • 21
    • 0037462597 scopus 로고    scopus 로고
    • Chromatin loosening by poly(ADP)-ribose polymerase (PARP) at Drosophila puff loci
    • Tulin A, &, Spradling A, (2003) Chromatin loosening by poly(ADP)-ribose polymerase (PARP) at Drosophila puff loci. Science 299, 560-562.
    • (2003) Science , vol.299 , pp. 560-562
    • Tulin, A.1    Spradling, A.2
  • 22
    • 46149108345 scopus 로고    scopus 로고
    • Rapid, transcription-independent loss of nucleosomes over a large chromatin domain at Hsp70 loci
    • Petesch SJ, &, Lis JT, (2008) Rapid, transcription-independent loss of nucleosomes over a large chromatin domain at Hsp70 loci. Cell 134, 74-84.
    • (2008) Cell , vol.134 , pp. 74-84
    • Petesch, S.J.1    Lis, J.T.2
  • 24
    • 0036710459 scopus 로고    scopus 로고
    • The functional role of poly(ADP-ribose)polymerase 1 as novel coactivator of NF-κB in inflammatory disorders
    • Hassa PO, &, Hottiger MO, (2002) The functional role of poly(ADP-ribose)polymerase 1 as novel coactivator of NF-κB in inflammatory disorders. Cell Mol Life Sci 59, 1534-1553.
    • (2002) Cell Mol Life Sci , vol.59 , pp. 1534-1553
    • Hassa, P.O.1    Hottiger, M.O.2
  • 25
    • 0038682011 scopus 로고    scopus 로고
    • PARP goes transcription
    • Kraus WL, &, Lis JT, (2003) PARP goes transcription. Cell 113, 677-683.
    • (2003) Cell , vol.113 , pp. 677-683
    • Kraus, W.L.1    Lis, J.T.2
  • 27
    • 84871934514 scopus 로고    scopus 로고
    • Recent advances in X-chromosome inactivation research
    • Pollex T, &, Heard E, (2012) Recent advances in X-chromosome inactivation research. Curr Opin Cell Biol 24, 825-832.
    • (2012) Curr Opin Cell Biol , vol.24 , pp. 825-832
    • Pollex, T.1    Heard, E.2
  • 29
    • 34250359929 scopus 로고    scopus 로고
    • Poly(ADP-ribose) polymerase 1 is inhibited by a histone H2A variant, MacroH2A, and contributes to silencing of the inactive X chromosome
    • Nusinow DA, Hernandez-Munoz I, Fazzio TG, Shah GM, Kraus WL, &, Panning B, (2007) Poly(ADP-ribose) polymerase 1 is inhibited by a histone H2A variant, MacroH2A, and contributes to silencing of the inactive X chromosome. J Biol Chem 282, 12851-12859.
    • (2007) J Biol Chem , vol.282 , pp. 12851-12859
    • Nusinow, D.A.1    Hernandez-Munoz, I.2    Fazzio, T.G.3    Shah, G.M.4    Kraus, W.L.5    Panning, B.6
  • 31
    • 34250626425 scopus 로고    scopus 로고
    • Meiotic sex chromosome inactivation
    • Turner JM, (2007) Meiotic sex chromosome inactivation. Development 134, 1823-1831.
    • (2007) Development , vol.134 , pp. 1823-1831
    • Turner, J.M.1
  • 33
    • 84864358475 scopus 로고    scopus 로고
    • Sex chromosome inactivation in germ cells: Emerging roles of DNA damage response pathways
    • Ichijima Y, Sin HS, &, Namekawa SH, (2012) Sex chromosome inactivation in germ cells: emerging roles of DNA damage response pathways. Cell Mol Life Sci 69, 2559-2572.
    • (2012) Cell Mol Life Sci , vol.69 , pp. 2559-2572
    • Ichijima, Y.1    Sin, H.S.2    Namekawa, S.H.3
  • 35
    • 55949109034 scopus 로고    scopus 로고
    • Telomeric chromatin: Roles in aging, cancer and hereditary disease
    • McCord RA, &, Broccoli D, (2008) Telomeric chromatin: roles in aging, cancer and hereditary disease. Mutat Res 647, 86-93.
    • (2008) Mutat Res , vol.647 , pp. 86-93
    • McCord, R.A.1    Broccoli, D.2
  • 36
    • 24944460598 scopus 로고    scopus 로고
    • Shelterin: The protein complex that shapes and safeguards human telomeres
    • De Lange T, (2005) Shelterin: the protein complex that shapes and safeguards human telomeres. Genes Dev 19, 2100-2110.
    • (2005) Genes Dev , vol.19 , pp. 2100-2110
    • De Lange, T.1
  • 38
    • 0035833257 scopus 로고    scopus 로고
    • Normal telomere length and chromosomal end capping in poly(ADP-ribose) polymerase-deficient mice and primary cells despite increased chromosomal instability
    • Samper E, Goytisolo FA, Menissier-de Murcia J, Gonzalez-Suarez E, Cigudosa JC, De Murcia G, &, Blasco MA, (2001) Normal telomere length and chromosomal end capping in poly(ADP-ribose) polymerase-deficient mice and primary cells despite increased chromosomal instability. J Cell Biol 154, 49-60.
    • (2001) J Cell Biol , vol.154 , pp. 49-60
    • Samper, E.1    Goytisolo, F.A.2    Menissier-De Murcia, J.3    Gonzalez-Suarez, E.4    Cigudosa, J.C.5    De Murcia, G.6    Blasco, M.A.7
  • 39
  • 41
    • 0035012606 scopus 로고    scopus 로고
    • DNA strand break-sensing molecule poly(ADP-ribose) polymerase cooperates with p53 in telomere function, chromosome stability, and tumor suppression
    • Tong WM, Hande MP, Lansdorp PM, &, Wang ZQ, (2001) DNA strand break-sensing molecule poly(ADP-ribose) polymerase cooperates with p53 in telomere function, chromosome stability, and tumor suppression. Mol Cell Biol 21, 4046-4054.
    • (2001) Mol Cell Biol , vol.21 , pp. 4046-4054
    • Tong, W.M.1    Hande, M.P.2    Lansdorp, P.M.3    Wang, Z.Q.4
  • 42
    • 36749045682 scopus 로고    scopus 로고
    • Tankyrase function at telomeres, spindle poles, and beyond
    • Hsiao SJ, &, Smith S, (2008) Tankyrase function at telomeres, spindle poles, and beyond. Biochimie 90, 83-92.
    • (2008) Biochimie , vol.90 , pp. 83-92
    • Hsiao, S.J.1    Smith, S.2
  • 43
    • 0034687248 scopus 로고    scopus 로고
    • Tankyrase promotes telomere elongation in human cells
    • Smith S, &, De Lange T, (2000) Tankyrase promotes telomere elongation in human cells. Curr Biol 10, 1299-1302.
    • (2000) Curr Biol , vol.10 , pp. 1299-1302
    • Smith, S.1    De Lange, T.2
  • 44
    • 0032553473 scopus 로고    scopus 로고
    • Tankyrase, a poly(ADP-ribose) polymerase at human telomeres
    • Smith S, Giriat I, Schmitt A, &, De Lange T, (1998) Tankyrase, a poly(ADP-ribose) polymerase at human telomeres. Science 282, 1484-1487.
    • (1998) Science , vol.282 , pp. 1484-1487
    • Smith, S.1    Giriat, I.2    Schmitt, A.3    De Lange, T.4
  • 45
    • 84870855799 scopus 로고    scopus 로고
    • Tankyrase-targeted therapeutics: Expanding opportunities in the PARP family
    • Riffell JL, Lord CJ, &, Ashworth A, (2012) Tankyrase-targeted therapeutics: expanding opportunities in the PARP family. Nat Rev Drug Discov 11, 923-936.
    • (2012) Nat Rev Drug Discov , vol.11 , pp. 923-936
    • Riffell, J.L.1    Lord, C.J.2    Ashworth, A.3
  • 46
    • 38149019842 scopus 로고    scopus 로고
    • Pericentric heterochromatin: Dynamic organization during early development in mammals
    • Probst AV, &, Almouzni G, (2008) Pericentric heterochromatin: dynamic organization during early development in mammals. Differentiation 76, 15-23.
    • (2008) Differentiation , vol.76 , pp. 15-23
    • Probst, A.V.1    Almouzni, G.2
  • 47
    • 4143099308 scopus 로고    scopus 로고
    • Mouse centric and pericentric satellite repeats form distinct functional heterochromatin
    • Guenatri M, Bailly D, Maison C, &, Almouzni G, (2004) Mouse centric and pericentric satellite repeats form distinct functional heterochromatin. J Cell Biol 166, 493-505.
    • (2004) J Cell Biol , vol.166 , pp. 493-505
    • Guenatri, M.1    Bailly, D.2    Maison, C.3    Almouzni, G.4
  • 48
    • 0344668731 scopus 로고    scopus 로고
    • Analysis of mammalian proteins involved in chromatin modification reveals new metaphase centromeric proteins and distinct chromosomal distribution patterns
    • Craig JM, Earle E, Canham P, Wong LH, Anderson M, &, Choo KH, (2003) Analysis of mammalian proteins involved in chromatin modification reveals new metaphase centromeric proteins and distinct chromosomal distribution patterns. Hum Mol Genet 12, 3109-3121.
    • (2003) Hum Mol Genet , vol.12 , pp. 3109-3121
    • Craig, J.M.1    Earle, E.2    Canham, P.3    Wong, L.H.4    Anderson, M.5    Choo, K.H.6
  • 49
    • 0037178870 scopus 로고    scopus 로고
    • Centromere proteins Cenpa, Cenpb, and Bub3 interact with poly(ADP-ribose) polymerase-1 protein and are poly(ADP-ribosyl)ated
    • Saxena A, Saffery R, Wong LH, Kalitsis P, &, Choo KH, (2002) Centromere proteins Cenpa, Cenpb, and Bub3 interact with poly(ADP-ribose) polymerase-1 protein and are poly(ADP-ribosyl)ated. J Biol Chem 277, 26921-26926.
    • (2002) J Biol Chem , vol.277 , pp. 26921-26926
    • Saxena, A.1    Saffery, R.2    Wong, L.H.3    Kalitsis, P.4    Choo, K.H.5
  • 50
    • 0037106439 scopus 로고    scopus 로고
    • Poly(ADP-ribose) polymerase 2 localizes to mammalian active centromeres and interacts with PARP-1, Cenpa, Cenpb and Bub3, but not Cenpc
    • Saxena A, Wong LH, Kalitsis P, Earle E, Shaffer LG, &, Choo KH, (2002) Poly(ADP-ribose) polymerase 2 localizes to mammalian active centromeres and interacts with PARP-1, Cenpa, Cenpb and Bub3, but not Cenpc. Hum Mol Genet 11, 2319-2329.
    • (2002) Hum Mol Genet , vol.11 , pp. 2319-2329
    • Saxena, A.1    Wong, L.H.2    Kalitsis, P.3    Earle, E.4    Shaffer, L.G.5    Choo, K.H.6
  • 51
    • 0037099483 scopus 로고    scopus 로고
    • Fission yeast CENP-B homologs nucleate centromeric heterochromatin by promoting heterochromatin-specific histone tail modifications
    • Nakagawa H, Lee JK, Hurwitz J, Allshire RC, Nakayama J, Grewal SI, Tanaka K, &, Murakami Y, (2002) Fission yeast CENP-B homologs nucleate centromeric heterochromatin by promoting heterochromatin-specific histone tail modifications. Genes Dev 16, 1766-1778.
    • (2002) Genes Dev , vol.16 , pp. 1766-1778
    • Nakagawa, H.1    Lee, J.K.2    Hurwitz, J.3    Allshire, R.C.4    Nakayama, J.5    Grewal, S.I.6    Tanaka, K.7    Murakami, Y.8
  • 52
    • 22144486573 scopus 로고    scopus 로고
    • Poly(ADP-ribose)polymerase-1 is required for integration of the human immunodeficiency virus type 1 genome near centromeric alphoid DNA in human and murine cells
    • Kameoka M, Nukuzuma S, Itaya A, Tanaka Y, Ota K, Inada Y, Ikuta K, &, Yoshihara K, (2005) Poly(ADP-ribose)polymerase-1 is required for integration of the human immunodeficiency virus type 1 genome near centromeric alphoid DNA in human and murine cells. Biochem Biophys Res Commun 334, 412-417.
    • (2005) Biochem Biophys Res Commun , vol.334 , pp. 412-417
    • Kameoka, M.1    Nukuzuma, S.2    Itaya, A.3    Tanaka, Y.4    Ota, K.5    Inada, Y.6    Ikuta, K.7    Yoshihara, K.8
  • 53
    • 55249118199 scopus 로고    scopus 로고
    • The heterochromatin protein 1 (HP1) family: Put away a bias toward HP1
    • Kwon SH, &, Workman JL, (2008) The heterochromatin protein 1 (HP1) family: put away a bias toward HP1. Mol Cells 26, 217-227.
    • (2008) Mol Cells , vol.26 , pp. 217-227
    • Kwon, S.H.1    Workman, J.L.2
  • 54
    • 1842733449 scopus 로고    scopus 로고
    • HP1 and the dynamics of heterochromatin maintenance
    • Maison C, &, Almouzni G, (2004) HP1 and the dynamics of heterochromatin maintenance. Nat Rev Mol Cell Biol 5, 296-304.
    • (2004) Nat Rev Mol Cell Biol , vol.5 , pp. 296-304
    • Maison, C.1    Almouzni, G.2
  • 55
    • 33847076248 scopus 로고    scopus 로고
    • Chromatin challenges during DNA replication and repair
    • Groth A, Rocha W, Verreault A, &, Almouzni G, (2007) Chromatin challenges during DNA replication and repair. Cell 128, 721-733.
    • (2007) Cell , vol.128 , pp. 721-733
    • Groth, A.1    Rocha, W.2    Verreault, A.3    Almouzni, G.4
  • 56
    • 0032522224 scopus 로고    scopus 로고
    • Functional association of poly(ADP-ribose) polymerase with DNA polymerase α-primase complex: A link between DNA strand break detection and DNA replication
    • Dantzer F, Nasheuer HP, Vonesch JL, De Murcia G, &, Menissier-de Murcia J, (1998) Functional association of poly(ADP-ribose) polymerase with DNA polymerase α-primase complex: a link between DNA strand break detection and DNA replication. Nucleic Acids Res 26, 1891-1898.
    • (1998) Nucleic Acids Res , vol.26 , pp. 1891-1898
    • Dantzer, F.1    Nasheuer, H.P.2    Vonesch, J.L.3    De Murcia, G.4    Menissier-De Murcia, J.5
  • 57
    • 59449101071 scopus 로고    scopus 로고
    • PARP-1 ensures regulation of replication fork progression by homologous recombination on damaged DNA
    • Sugimura K, Takebayashi S, Taguchi H, Takeda S, &, Okumura K, (2008) PARP-1 ensures regulation of replication fork progression by homologous recombination on damaged DNA. J Cell Biol 183, 1203-1212.
    • (2008) J Cell Biol , vol.183 , pp. 1203-1212
    • Sugimura, K.1    Takebayashi, S.2    Taguchi, H.3    Takeda, S.4    Okumura, K.5
  • 58
    • 0033198919 scopus 로고    scopus 로고
    • Poly(ADP-ribosyl)ation reactions in the regulation of nuclear functions
    • D'Amours D, Desnoyers S, D'Silva I, &, Poirier GG, (1999) Poly(ADP-ribosyl)ation reactions in the regulation of nuclear functions. Biochem J 342, 249-268.
    • (1999) Biochem J , vol.342 , pp. 249-268
    • D'Amours, D.1    Desnoyers, S.2    D'Silva, I.3    Poirier, G.G.4
  • 60
    • 0029808055 scopus 로고    scopus 로고
    • The expression of poly(ADP-ribose) polymerase during differentiation- linked DNA replication reveals that it is a component of the multiprotein DNA replication complex
    • Simbulan-Rosenthal CM, Rosenthal DS, Hilz H, Hickey R, Malkas L, Applegren N, Wu Y, Bers G, &, Smulson ME, (1996) The expression of poly(ADP-ribose) polymerase during differentiation-linked DNA replication reveals that it is a component of the multiprotein DNA replication complex. Biochemistry 35, 11622-11633.
    • (1996) Biochemistry , vol.35 , pp. 11622-11633
    • Simbulan-Rosenthal, C.M.1    Rosenthal, D.S.2    Hilz, H.3    Hickey, R.4    Malkas, L.5    Applegren, N.6    Wu, Y.7    Bers, G.8    Smulson, M.E.9
  • 61
    • 0015962328 scopus 로고
    • The relationship between cell growth, macromolecular synthesis and poly ADP-ribose polymerase in lymphoid cells
    • Lehmann AR, Kirk-Bell S, Shall S, &, Whish WJ, (1974) The relationship between cell growth, macromolecular synthesis and poly ADP-ribose polymerase in lymphoid cells. Exp Cell Res 83, 63-72.
    • (1974) Exp Cell Res , vol.83 , pp. 63-72
    • Lehmann, A.R.1    Kirk-Bell, S.2    Shall, S.3    Whish, W.J.4
  • 62
    • 0018796405 scopus 로고
    • Nuclear protein modification and chromatin substructure. 3. Relationship between poly(adenosine diphosphate) ribosylation and different functional forms of chromatin
    • Jump DB, Butt TR, &, Smulson M, (1979) Nuclear protein modification and chromatin substructure. 3. Relationship between poly(adenosine diphosphate) ribosylation and different functional forms of chromatin. Biochemistry 18, 983-990.
    • (1979) Biochemistry , vol.18 , pp. 983-990
    • Jump, D.B.1    Butt, T.R.2    Smulson, M.3
  • 63
    • 0024781397 scopus 로고
    • DNA replication and poly(ADP-ribosyl)ation of chromatin
    • Anachkova B, Russev G, &, Poirier GG, (1989) DNA replication and poly(ADP-ribosyl)ation of chromatin. Cytobios 58, 19-28.
    • (1989) Cytobios , vol.58 , pp. 19-28
    • Anachkova, B.1    Russev, G.2    Poirier, G.G.3
  • 64
    • 77649165394 scopus 로고    scopus 로고
    • Maintaining genome stability at the replication fork
    • Branzei D, &, Foiani M, (2010) Maintaining genome stability at the replication fork. Nat Rev Mol Cell Biol 11, 208-219.
    • (2010) Nat Rev Mol Cell Biol , vol.11 , pp. 208-219
    • Branzei, D.1    Foiani, M.2
  • 65
    • 2342524565 scopus 로고    scopus 로고
    • Ablation of PARP-1 does not interfere with the repair of DNA double-strand breaks, but compromises the reactivation of stalled replication forks
    • Yang YG, Cortes U, Patnaik S, Jasin M, &, Wang ZQ, (2004) Ablation of PARP-1 does not interfere with the repair of DNA double-strand breaks, but compromises the reactivation of stalled replication forks. Oncogene 23, 3872-3882.
    • (2004) Oncogene , vol.23 , pp. 3872-3882
    • Yang, Y.G.1    Cortes, U.2    Patnaik, S.3    Jasin, M.4    Wang, Z.Q.5
  • 68
    • 0036844024 scopus 로고    scopus 로고
    • The nucleolar remodeling complex NoRC mediates heterochromatin formation and silencing of ribosomal gene transcription
    • Santoro R, Li J, &, Grummt I, (2002) The nucleolar remodeling complex NoRC mediates heterochromatin formation and silencing of ribosomal gene transcription. Nat Genet 32, 393-396.
    • (2002) Nat Genet , vol.32 , pp. 393-396
    • Santoro, R.1    Li, J.2    Grummt, I.3
  • 69
    • 84864680102 scopus 로고    scopus 로고
    • Formation of nuclear heterochromatin: The nucleolar point of view
    • Guetg C, &, Santoro R, (2012) Formation of nuclear heterochromatin: the nucleolar point of view. Epigenetics 7, 811-814.
    • (2012) Epigenetics , vol.7 , pp. 811-814
    • Guetg, C.1    Santoro, R.2
  • 70
    • 83455197111 scopus 로고    scopus 로고
    • The epigenetics of the nucleolus: Structure and function of active and silent ribosomal RNA genes
    • Santoro R, (2011) The epigenetics of the nucleolus: structure and function of active and silent ribosomal RNA genes. Protein Rev 15, 57-82.
    • (2011) Protein Rev , vol.15 , pp. 57-82
    • Santoro, R.1
  • 72
    • 13244277994 scopus 로고    scopus 로고
    • The chromatin remodeling complex NoRC controls replication timing of rRNA genes
    • Li J, Santoro R, Koberna K, &, Grummt I, (2005) The chromatin remodeling complex NoRC controls replication timing of rRNA genes. EMBO J 24, 120-127.
    • (2005) EMBO J , vol.24 , pp. 120-127
    • Li, J.1    Santoro, R.2    Koberna, K.3    Grummt, I.4
  • 73
    • 33646147563 scopus 로고    scopus 로고
    • Intergenic transcripts regulate the epigenetic state of rRNA genes
    • Mayer C, Schmitz KM, Li J, Grummt I, &, Santoro R, (2006) Intergenic transcripts regulate the epigenetic state of rRNA genes. Mol Cell 22, 351-361.
    • (2006) Mol Cell , vol.22 , pp. 351-361
    • Mayer, C.1    Schmitz, K.M.2    Li, J.3    Grummt, I.4    Santoro, R.5
  • 74
    • 74149088040 scopus 로고    scopus 로고
    • Intergenic transcripts originating from a subclass of ribosomal DNA repeats silence ribosomal RNA genes in trans
    • Santoro R, Schmitz KM, Sandoval J, &, Grummt I, (2010) Intergenic transcripts originating from a subclass of ribosomal DNA repeats silence ribosomal RNA genes in trans. EMBO Rep 11, 52-58.
    • (2010) EMBO Rep , vol.11 , pp. 52-58
    • Santoro, R.1    Schmitz, K.M.2    Sandoval, J.3    Grummt, I.4
  • 75
    • 41449089409 scopus 로고    scopus 로고
    • RNA interference guides histone modification during the S phase of chromosomal replication
    • Kloc A, Zaratiegui M, Nora E, &, Martienssen R, (2008) RNA interference guides histone modification during the S phase of chromosomal replication. Curr Biol 18, 490-495.
    • (2008) Curr Biol , vol.18 , pp. 490-495
    • Kloc, A.1    Zaratiegui, M.2    Nora, E.3    Martienssen, R.4
  • 76
    • 38949208022 scopus 로고    scopus 로고
    • Cell cycle control of centromeric repeat transcription and heterochromatin assembly
    • Chen ES, Zhang K, Nicolas E, Cam HP, Zofall M, &, Grewal SI, (2008) Cell cycle control of centromeric repeat transcription and heterochromatin assembly. Nature 451, 734-737.
    • (2008) Nature , vol.451 , pp. 734-737
    • Chen, E.S.1    Zhang, K.2    Nicolas, E.3    Cam, H.P.4    Zofall, M.5    Grewal, S.I.6
  • 78
    • 0036509836 scopus 로고    scopus 로고
    • Higher-order structure in pericentric heterochromatin involves a distinct pattern of histone modification and an RNA component
    • Maison C, Bailly D, Peters AH, Quivy JP, Roche D, Taddei A, Lachner M, Jenuwein T, &, Almouzni G, (2002) Higher-order structure in pericentric heterochromatin involves a distinct pattern of histone modification and an RNA component. Nat Genet 30, 329-334.
    • (2002) Nat Genet , vol.30 , pp. 329-334
    • Maison, C.1    Bailly, D.2    Peters, A.H.3    Quivy, J.P.4    Roche, D.5    Taddei, A.6    Lachner, M.7    Jenuwein, T.8    Almouzni, G.9
  • 79
    • 35948951117 scopus 로고    scopus 로고
    • Proliferation-dependent and cell cycle regulated transcription of mouse pericentric heterochromatin
    • Lu J, &, Gilbert DM, (2007) Proliferation-dependent and cell cycle regulated transcription of mouse pericentric heterochromatin. J Cell Biol 179, 411-421.
    • (2007) J Cell Biol , vol.179 , pp. 411-421
    • Lu, J.1    Gilbert, D.M.2
  • 81
    • 33747453473 scopus 로고    scopus 로고
    • Insulators: Exploiting transcriptional and epigenetic mechanisms
    • Gaszner M, &, Felsenfeld G, (2006) Insulators: exploiting transcriptional and epigenetic mechanisms. Nat Rev Genet 7, 703-713.
    • (2006) Nat Rev Genet , vol.7 , pp. 703-713
    • Gaszner, M.1    Felsenfeld, G.2
  • 82
    • 78549280576 scopus 로고    scopus 로고
    • Poly(ADP-ribose) polymerase-1 (PARP-1) contributes to the barrier function of a vertebrate chromatin insulator
    • Aker M, Bomsztyk K, &, Emery DW, (2010) Poly(ADP-ribose) polymerase-1 (PARP-1) contributes to the barrier function of a vertebrate chromatin insulator. J Biol Chem 285, 37589-37597.
    • (2010) J Biol Chem , vol.285 , pp. 37589-37597
    • Aker, M.1    Bomsztyk, K.2    Emery, D.W.3
  • 85
    • 67649280395 scopus 로고    scopus 로고
    • Persistence of histone H2AX phosphorylation after meiotic chromosome synapsis and abnormal centromere cohesion in poly (ADP-ribose) polymerase (Parp-1) null oocytes
    • Yang F, Baumann C, &, De La Fuente R, (2009) Persistence of histone H2AX phosphorylation after meiotic chromosome synapsis and abnormal centromere cohesion in poly (ADP-ribose) polymerase (Parp-1) null oocytes. Dev Biol 331, 326-338.
    • (2009) Dev Biol , vol.331 , pp. 326-338
    • Yang, F.1    Baumann, C.2    De La Fuente, R.3


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