Phosphorylation-mediated PTEN conformational closure and deactivation revealed with protein semisynthesis

eLife

Volumn 2013, Issue 2, 2013, Pages

  Bolduc, David ^a   Rahdar, Meghdad ^b   Tu Sekine, Becky ^a   Sivakumaren, Sindhu Carmen ^a   Raben, Daniel ^a   Amzel, L Mario ^a   Devreotes, Peter ^a   Gabelli, Sandra B ^a   Cole, Philip ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PHOSPHATIDYLINOSITOL 3, 4, 5 TRISPHOSPHATE 3 PHOSPHATASE; PHOSPHOPEPTIDE; UNCLASSIFIED DRUG; ALKALINE PHOSPHATASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE;

ANION EXCHANGE CHROMATOGRAPHY; ARTICLE; CONFORMATIONAL TRANSITION; ENZYME KINETICS; LIMIT OF QUANTITATION; MUTAGENESIS; PEPTIDE SYNTHESIS; PROTEIN DENATURATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN PURIFICATION; PROTEIN STRUCTURE; PROTEIN SYNTHESIS; RADIATION SCATTERING; REGULATORY MECHANISM; THIN LAYER CHROMATOGRAPHY; X RAY CRYSTALLOGRAPHY; AMINO ACID SEQUENCE; CHEMISTRY; ION EXCHANGE CHROMATOGRAPHY; METABOLISM; MOLECULAR GENETICS; PHOSPHORYLATION; PROTEIN CONFORMATION; PROTEIN DEGRADATION; SMALL ANGLE SCATTERING;

ALKALINE PHOSPHATASE; AMINO ACID SEQUENCE; CHROMATOGRAPHY, ION EXCHANGE; MOLECULAR SEQUENCE DATA; PHOSPHORYLATION; PROTEIN CONFORMATION; PROTEOLYSIS; PTEN PHOSPHOHYDROLASE; SCATTERING, SMALL ANGLE;

EID: 84880124600     PISSN: None     EISSN: 2050084X     Source Type: Journal    
DOI: 10.7554/eLife.00691     Document Type: Article

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