Allosteric Activation of PTEN Phosphatase by Phosphatidylinositol 4,5-Bisphosphate

Journal of Biological Chemistry

Volumn 278, Issue 36, 2003, Pages 33617-33620

  Campbell, Robert B ^a   Liu, Fenghua ^a   Ross, Alonzo H ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHROMOSOMES; CONFORMATIONS; ENZYMES; HYDROLYSIS; HYDROPHOBICITY; MONOMERS; PHOSPHATES; PHOSPHOLIPIDS; PHYSIOLOGY; TUMORS;

MUTATIONS;

BIOCHEMISTRY;

PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE; UNCLASSIFIED DRUG; FATTY ACID; GLUTATHIONE TRANSFERASE; HYBRID PROTEIN; ION; PHOSPHATASE; PHOSPHATE; PTEN PROTEIN, HUMAN; RECOMBINANT PROTEIN; TUMOR SUPPRESSOR PROTEIN;

ALLOSTERISM; ANIMAL CELL; APOPTOSIS; ARTICLE; CELL PROLIFERATION; CHROMOSOME 10; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME SPECIFICITY; GENE; GENE DELETION; GENE MUTATION; HYDROPHOBICITY; NONHUMAN; PHOSPHOLIPID MEMBRANE; PRIORITY JOURNAL; PTEN GENE; TUMOR SUPPRESSOR GENE; BINDING SITE; CHEMISTRY; DOSE RESPONSE; HUMAN; HYDROLYSIS; KINETICS; LIPID BILAYER; LIPID METABOLISM; METABOLISM; MUTATION; NUCLEOTIDE SEQUENCE; PHYSIOLOGY; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN MOTIF; PROTEIN TERTIARY STRUCTURE; TIME;

ANIMALIA;

ALLOSTERIC SITE; AMINO ACID MOTIFS; DNA MUTATIONAL ANALYSIS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; FATTY ACIDS; GLUTATHIONE TRANSFERASE; HUMANS; HYDROLYSIS; IONS; KINETICS; LIPID BILAYERS; LIPID METABOLISM; MUTATION; PHOSPHATES; PHOSPHATIDYLINOSITOL 4,5-DIPHOSPHATE; PHOSPHORIC MONOESTER HYDROLASES; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; PTEN PHOSPHOHYDROLASE; RECOMBINANT FUSION PROTEINS; RECOMBINANT PROTEINS; TIME FACTORS; TUMOR SUPPRESSOR PROTEINS;

EID: 0141817911     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.C300296200     Document Type: Article

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