Crystal structure of a phosphorylated Smad2: Recognition of phosphoserine by the MH2 domain and insights on Smad function in TGF-β signaling

Molecular Cell

Volumn 8, Issue 6, 2001, Pages 1277-1289

  Wu, Jia Wei ^a   Hu, Min ^a   Chai, Jijie ^a   Seoane, Joan ^b,c   Huse, Morgan ^c   Rigotti, Daniel J ^d   Kyin, Saw ^a,c   Fairman, Robert ^d   Massagué, Joan ^b   Shi, Yigong ^a  

^a PRINCETON UNIVERSITY   (United States)

^b MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^c ROCKEFELLER UNIVERSITY   (United States)

^d HAVERFORD COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DOCKING PROTEIN; PHOSPHOPROTEIN; PHOSPHOSERINE; PROTEIN SERINE THREONINE KINASE; RECEPTOR PROTEIN; SMAD PROTEIN; SMAD2 PROTEIN; SMAD4 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; CANCER INHIBITION; CARBOXY TERMINAL SEQUENCE; CRYSTAL STRUCTURE; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; PROTEIN TARGETING; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; SITE DIRECTED MUTAGENESIS;

EID: 18244362844     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1097-2765(01)00421-X     Document Type: Article

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