Novel Mechanism of PTEN Regulation by Its Phosphatidylinositol 4,5-Bisphosphate Binding Motif Is Critical for Chemotaxis

Journal of Biological Chemistry

Volumn 279, Issue 16, 2004, Pages 16606-16613

  Iijima, Miho ^a   Huang, Yi Elaine ^a   Luo, Hongbo R ^a   Vazquez, Francisca ^a   Devreotes, Peter N ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MEMBRANES; CATALYSIS; CELLS; ENZYMES; MUTAGENESIS;

CHEMOTAXING CELLS; MEMBRANE ASSOCIATION;

BIOCHEMISTRY;

PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE;

ACTIN FILAMENT; AMINO TERMINAL SEQUENCE; ARTICLE; CANCER INHIBITION; CATALYSIS; CELLULAR DISTRIBUTION; CHEMOTAXIS; CYTOSKELETON; ENZYME ACTIVITY; ENZYME INACTIVATION; ENZYME LOCALIZATION; GENE MUTATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN LOCALIZATION; PROTEIN MOTIF; PROTEIN SYNTHESIS REGULATION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; AMINO ACID MOTIFS; ANIMALS; BINDING SITES; CHEMOTAXIS; DICTYOSTELIUM; PHOSPHATIDYLINOSITOL 4,5-DIPHOSPHATE; PHOSPHORIC MONOESTER HYDROLASES; SIGNAL TRANSDUCTION;

PSEUDOPODA;

EID: 1942501586     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M312098200     Document Type: Article

References (41)

1. Klein, P., Knox, B., Borleis, J., and Devreotes, P. (1987) J. Biol. Chem. 262, 352-357
2. Klein, P., Theibert, A., and Devreotes, P. (1988) Methods Enzymol. 159, 267-278
3. Xiao, Z., Zhang, N., Murphy, D. B., and Devreotes, P. N. (1997) J. Cell Biol. 139, 365-374
4. Servant, G., Weiner, O. D., Neptune, E. R., Sedat, J. W., and Bourne, H. R. (1999) Mol. Biol. Cell 10, 1163-1178
5. Jin, T., Zhang, N., Long, Y., Parent, C. A., and Devreotes, P. N. (2000) Science 287, 1034-1036
6. Parent, C. A., Blacklock, B. J., Froehlich, W. M., Murphy, D. B., and Devreotesm P. N. (1998) Cell 95, 81-91
7. Haugh, J. M., Codazzi, F., Teruel, M., and Meyer, T. (2000) J. Cell Biol. 151, 1269-1280
8. Derman, M. P., Toker, A., Hartwig, J. H., Spokes, K., Falck, J. R., Chen, C. S., Cantley, L. C., and Cantley, L. G. (1997) J. Biol. Chem. 272, 6465-6470
9. Niggli, V. (2000) FEBS Lett. 473, 217-221
10. Weiner, O. D., Neilsen, P. O., Prestwich, G. D., Kirschner, M. W., Cantley, L. C., and Bourne, H. R. (2002) Nat. Cell Biol. 4, 509-513
11. Funamoto, S., Meili, R., Lee, S., Parry, L., and Firtel, R. A. (2002) Cell 109, 611-623
12. Iijima, M., and Devreotes, P. (2002) Cell 109, 599-610
13. Huang, Y. E., Iijima, M., Parent, C. A., Funamoto, S., Firtel, R. A., and Devreotes, P. (2003) Mol. Biol. Cell 14, 1913-1922
14. Luo, H. R., Huang, Y. E., Chen, J. C., Saiardi, A., Iijima, M., Ye, K., Huang, Y., Nagata, E., Devreotes, P., and Snyder, S. H. (2003) Cell 114, 559-572
15. Li, J., Yen, C., Liaw, D., Podsypanina, K., Bose, S., Wang, S. I., Puc, J., Miliaresis, C., Rodgers, L., McCombie, R., Bigner, S. H., Giovanella, B. C., Ittmann, M., Tycko, B., Hibshoosh, H., Wigler, M. H., and Parsons, R. (1997) Science 275, 1943-1947
16. Steck, P. A., Pershouse, M. A., Jasser, S. A., Yung, W. K., Lin, H., Ligon, A. H., Langford, L. A., Baumgard, M. L., Hattier, T., Davis, T., Frye, C. Hu, R., Swedlund, B., Teng, D. H., and Tavtigian, S. V. (1997) Nat. Genet. 15, 356-362
17. Maehama, T., and Dixon, J. E. (1998) J. Biol. Chem. 273, 13375-13378
18. Myers, M. P., Pass, I., Batty, I. H., Van der Kaay, J. Stolarov, J. P., Hemmings, B. A., Wigler, M. H., Downes, C. P., and Tanks, N. K. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 13513-13518
19. Lee, J. O., Yang, H., Georgescu, M. M., Di Cristofano, A., Maehama, T., Shi, Y., Dixon, J. E., Pandolfi, P., and Pavletich, N. P. (1999) Cell 99, 323-334
20. Hess, H. H., and Derr, J. E. (1975) Anal. Biochem. 63, 607-613
21. Iijima, M., Huang, Y. E., and Devreotes, P. (2002) Dev. Cell 3, 469-478
22. Altschul, S. F., Madden, T. L., Schaffer, A. A., Zhang, J., Zhang, Z., Miller, W., and Lipman, D. J. (1997) Nucleic Acids Res. 25, 3389-3402
23. Miller, R. T., Jones, D. T., and Thornton, J. M. (1996) FASEB J. 10, 171-178
24. Wang, F., Herzmark, P., Weiner, O. D., Srinivasan, S., Servant, G., and Bourne, H. R. (2002) Nat. Cell Biol. 4, 513-518
25. Myers, M. P., Stolarov, J. P., Eng, C., Li, J., Wang, S. I., Wigler, M. H., Parsons, R., and Tonks, N. K. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 9052-9057
26. Tamura, M., Gu, J., Matsumoto, K., Aota, S., Parsons, R., and Yamada, K. M. (1998) Science 280, 1614-1617
27. Gu, J., Tamura, M., Pankov, R., Danen, E. H., Takino, T., Matsumoto, K., and Yamada, K. M. (1999) J. Cell Biol. 146, 389-403
28. Tamura, M., Gu, J., Takino, T., and Yamada, K. M. (1999) Cancer Res. 59, 442-449
29. Weng, L. P., Smith, W. M., Brown, J. L., and Eng, C. (2001) Hum. Mol. Genet. 10, 605-616
30. Wu, Y., Dowbenko, D., Spencer, S., Laura, R., Lee, J., Gu, Q., and Lasky, L. A. (2000) J. Biol. Chem. 275, 21477-21485
31. Leslie, N. R., Bennett, D., Gray, A., Pass, I., Hoang-Xuan, K., and Downes, C. P. (2001) Biochem. J. 357, 427-435
32. Das, S., Dixon, J. E., and Cho, W. (2003) Proc. Natl. Acad. Sci. U. S. A. 100, 7491-7496
33. Li, Z., Hannigan, M., Mo, Z., Liu, B., Lu, W., Wu, Y., Smrcka, A. V., Wu, G., Li, L., Liu, M., Huang, C. K., and Wu, D. (2003) Cell 114, 215-227
34. Fanning, A. S., and Anderson, J. M. (1999) J. Clin. Investig. 103, 767-772
35. Wu, X., Hepner, K., Castelino-Prabhu, S., Do, D., Kaye, M. B., Yuan, X. J., Wood, J., Ross, C., Sawyers, C. L., and Whang, Y. E. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 4233-4238
36. Maehama, T., Taylor, G. S., and Dixon, J. E. (2001) Annu. Rev. Biochem. 70, 247-279
37. Campbell, R. B., Liu, F., and Ross, A. H. (2003) J. Biol. Chem. 278, 33617-33620
38. McConnachie, G., Pass, I., Walker, S. M., and Downes, C. P. (2003) Biochem. J. 371, 947-955
39. Chen, L., Janetopoulos, C., Huang, Y. E., Iijima, M., Borleis, J., and Devreotes, P. N. (2003) Mol. Biol. Cell 14, 5028-5037
40. Xu, J., Wang, F., Van Keymeulen, A., Herzmark, P., Straight, A., Kelly, K., Takuwa, Y., Sugimoto, N., Mitchison, T., and Bourne, H. R. (2003) Cell 114, 201-214
41. Devreotes, P., Fontana, D., Klein, P., Sherring, J., and Theibert, A. (1987) Methods Cell Biol. 28, 299-331