Synthesis, molecular modeling study, preliminary antibacterial, and antitumor evaluation of N-substituted naphthalimides and their structural analogues

Medicinal Chemistry Research

Volumn 22, Issue 5, 2013, Pages 2360-2375

  El Azab, Adel S ^a,b   Alanazi, Amer M ^a   Abdel Aziz, Naglaa I ^c   Al Suwaidan, Ibrahim A ^a   El Sayed, Magda A A ^c   El Sherbeny, Magda A ^c   Abdel Aziz, Alaa A M ^a,c  

^a KING SAUD UNIVERSITY   (Saudi Arabia)

^b Al Azhar University   (Egypt)

^c University of Mansoura   (Egypt)

Author keywords

Antibacterial activity; Antitumor evaluation; Cyclic imides; Modeling; Molecular modeling; Naphthalimides; Synthesis

Indexed keywords

2 (2,4,6 TRIMETHOXYPHENYL) 1H BENZO [DE] ISOQUINOLINE 1,3 (2) DIONE; 6 (2,4,6 TRICHLOROPHENYL) 5H PYRROLO[3,4 B]PYRAZINE 5,7 (6H) DIONE; CARBOXYLIC ACID DERIVATIVE; DNA TOPOISOMERASE (ATP HYDROLYSING); UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ANTINEOPLASTIC ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; GRAM NEGATIVE BACTERIUM; MOLECULAR MODEL; QUANTITATIVE STRUCTURE ACTIVITY RELATION; TUMOR CELL LINE;

EID: 84879688156     PISSN: 10542523     EISSN: 15548120     Source Type: Journal    
DOI: 10.1007/s00044-012-0230-8     Document Type: Article

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