Antitrypanosomal activity of quaternary naphthalimide derivatives

Bioorganic and Medicinal Chemistry Letters

Volumn 17, Issue 6, 2007, Pages 1590-1593

  Muth, Mathias ^a   Hoerr, Verena ^a,b   Glaser, Melanie ^b   Ponte Sucre, Alicia ^a,c   Moll, Heidrun ^a   Stich, August ^b   Holzgrabe, Ulrike ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b Medical Mission Hospital   (Germany)

^c UNIVERSIDAD CENTRAL DE VENEZUELA   (Venezuela)

Author keywords

Quaternary and tertiary naphthalimides; Sleeping sickness; Trypanosoma brucei

Indexed keywords

ANTITRYPANOSOMAL AGENT; BISNAFIDE MESYLATE; DNA; LU 79552; NAPHTHALIMIDE DERIVATIVE; UNCLASSIFIED DRUG;

AFRICAN TRYPANOSOMIASIS; ARTICLE; CONCENTRATION (PARAMETERS); DRUG ACTIVITY; DRUG POTENCY; DRUG SCREENING; DRUG SYNTHESIS; IC 50; MICROWAVE RADIATION; NONHUMAN; PRODUCTIVITY; TRYPANOSOMA; TRYPANOSOMA RHODESIENSE; TRYPANOSOMIASIS;

ANIMALS; DRUG EVALUATION, PRECLINICAL; HUMANS; INDICATORS AND REAGENTS; MICE; NAPHTHALIMIDES; STRUCTURE-ACTIVITY RELATIONSHIP; TRYPANOCIDAL AGENTS; TRYPANOSOMA BRUCEI BRUCEI;

TRYPANOSOMA BRUCEI; TRYPANOSOMA BRUCEI GAMBIENSE;

EID: 33847071115     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2006.12.088     Document Type: Article

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