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Volumn 5, Issue 6, 2013, Pages 1571-1586

Bromodomain proteins in HIV Infection

Author keywords

BRD2; BRD4; Bromodomains; CBP; HIV; P300; PBAF; PCAF; TRIM28

Indexed keywords

AGENTS AFFECTING PROTEIN METABOLISM; BARRIER TO AUTOINTEGRATION FACTOR; BINDING PROTEIN; BRG1 PROTEIN; BRM PROTEIN; BROMODOMAIN CONTAINING PROTEIN 2; BROMODOMAIN CONTAINING PROTEIN 4; BROMODOMAIN PROTEIN; HISTONE ACETYLTRANSFERASE PCAF; HUMAN IMMUNODEFICIENCY VIRUS PROTEIN; I BET; JQ 1; PROTEIN INHIBITOR; PROTEIN SP140; TRANSACTIVATOR PROTEIN; TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 1; UNCLASSIFIED DRUG; VALPROIC ACID; VORINOSTAT;

EID: 84879314122     PISSN: 19994915     EISSN: None     Source Type: Journal    
DOI: 10.3390/v5061571     Document Type: Review
Times cited : (33)

References (87)
  • 1
    • 79952534189 scopus 로고    scopus 로고
    • Regulation of chromatin by histone modifications
    • Bannister, A.J.; Kouzarides, T. Regulation of chromatin by histone modifications. Cell Res. 2011, 21, 381-395.
    • (2011) Cell Res. , vol.21 , pp. 381-395
    • Bannister, A.J.1    Kouzarides, T.2
  • 2
    • 49349107518 scopus 로고    scopus 로고
    • Lysine acetylation: Codified crosstalk with other posttranslational modifications
    • Yang, X.J.; Seto, E. Lysine acetylation: Codified crosstalk with other posttranslational modifications. Mol. Cell 2008, 31, 449-461.
    • (2008) Mol. Cell , vol.31 , pp. 449-461
    • Yang, X.J.1    Seto, E.2
  • 4
    • 0034051227 scopus 로고    scopus 로고
    • Acetylation of histones and transcription-related factors
    • Sterner, D.E.; Berger, S.L. Acetylation of histones and transcription-related factors. Microbiol. Mol. Biol. Rev. 2000, 64, 435-459.
    • (2000) Microbiol. Mol. Biol. Rev. , vol.64 , pp. 435-459
    • Sterner, D.E.1    Berger, S.L.2
  • 5
    • 0033519641 scopus 로고    scopus 로고
    • Structure and ligand of a histone acetyltransferase bromodomain
    • Dhalluin, C.; Carlson, J.E.; Zeng, L.; He, C.; Aggarwal, A.K.; Zhou, M.M. Structure and ligand of a histone acetyltransferase bromodomain. Nature 1999, 399, 491-496.
    • (1999) Nature , vol.399 , pp. 491-496
    • Dhalluin, C.1    Carlson, J.E.2    Zeng, L.3    He, C.4    Aggarwal, A.K.5    Zhou, M.M.6
  • 6
    • 84864578590 scopus 로고    scopus 로고
    • The bromodomain interaction module
    • Filippakopoulos, P.; Knapp, S. The bromodomain interaction module. FEBS Lett. 2012, 586, 2692-2704.
    • (2012) FEBS Lett. , vol.586 , pp. 2692-2704
    • Filippakopoulos, P.1    Knapp, S.2
  • 7
    • 0026580006 scopus 로고
    • Brahma: A regulator of Drosophila homeotic genes structurally related to the yeast transcriptional activator SNF2/SWI2
    • Tamkun, J.W.; Deuring, R.; Scott, M.P.; Kissinger, M.; Pattatucci, A.M.; Kaufman, T.C.; Kennison, J.A. Brahma: A regulator of Drosophila homeotic genes structurally related to the yeast transcriptional activator SNF2/SWI2. Cell 1992, 68, 561-572.
    • (1992) Cell , vol.68 , pp. 561-572
    • Tamkun, J.W.1    Deuring, R.2    Scott, M.P.3    Kissinger, M.4    Pattatucci, A.M.5    Kaufman, T.C.6    Kennison, J.A.7
  • 13
    • 70349277568 scopus 로고    scopus 로고
    • Short communication: Activation of latent HIV type 1 gene expression by suberoylanilide hydroxamic acid (SAHA), an HDAC inhibitor approved for use to treat cutaneous T cell lymphoma
    • Edelstein, L.C.; Micheva-Viteva, S.; Phelan, B.D.; Dougherty, J.P. Short communication: Activation of latent HIV type 1 gene expression by suberoylanilide hydroxamic acid (SAHA), an HDAC inhibitor approved for use to treat cutaneous T cell lymphoma. AIDS Res. Hum. Retroviruses 2009, 25, 883-887.
    • (2009) AIDS Res. Hum. Retroviruses , vol.25 , pp. 883-887
    • Edelstein, L.C.1    Micheva-Viteva, S.2    Phelan, B.D.3    Dougherty, J.P.4
  • 15
    • 0027258123 scopus 로고
    • Chromatin disruption in the promoter of human immunodeficiency virus type 1 during transcriptional activation
    • Verdin, E.; Paras, P., Jr.; van Lint, C. Chromatin disruption in the promoter of human immunodeficiency virus type 1 during transcriptional activation. EMBO J. 1993, 12, 3249-3259.
    • (1993) EMBO J. , vol.12 , pp. 3249-3259
    • Verdin, E.1    Paras Jr., P.2    van Lint, C.3
  • 16
    • 0347624643 scopus 로고    scopus 로고
    • Regulation of HIV-1 gene expression by histone acetylation and factor recruitment at the LTR promoter
    • Lusic, M.; Marcello, A.; Cereseto, A.; Giacca, M. Regulation of HIV-1 gene expression by histone acetylation and factor recruitment at the LTR promoter. EMBO J. 2003, 22, 6550-6561.
    • (2003) EMBO J. , vol.22 , pp. 6550-6561
    • Lusic, M.1    Marcello, A.2    Cereseto, A.3    Giacca, M.4
  • 17
    • 77951954237 scopus 로고    scopus 로고
    • HIV-1 Tat assembles a multifunctional transcription elongation complex and stably associates with the 7SK snRNP
    • Sobhian, B.; Laguette, N.; Yatim, A.; Nakamura, M.; Levy, Y.; Kiernan, R.; Benkirane, M. HIV-1 Tat assembles a multifunctional transcription elongation complex and stably associates with the 7SK snRNP. Mol. Cell 2010, 38, 439-451.
    • (2010) Mol. Cell , vol.38 , pp. 439-451
    • Sobhian, B.1    Laguette, N.2    Yatim, A.3    Nakamura, M.4    Levy, Y.5    Kiernan, R.6    Benkirane, M.7
  • 18
    • 77951959240 scopus 로고    scopus 로고
    • HIV-1 Tat and host AFF4 recruit two transcription elongation factors into a bifunctional complex for coordinated activation of HIV-1 transcription
    • He, N.; Liu, M.; Hsu, J.; Xue, Y.; Chou, S.; Burlingame, A.; Krogan, N.J.; Alber, T.; Zhou, Q. HIV-1 Tat and host AFF4 recruit two transcription elongation factors into a bifunctional complex for coordinated activation of HIV-1 transcription. Mol. Cell 2010, 38, 428-438.
    • (2010) Mol. Cell , vol.38 , pp. 428-438
    • He, N.1    Liu, M.2    Hsu, J.3    Xue, Y.4    Chou, S.5    Burlingame, A.6    Krogan, N.J.7    Alber, T.8    Zhou, Q.9
  • 19
    • 0032506242 scopus 로고    scopus 로고
    • HIV-1 tat transactivator recruits p300 and CREB-binding protein histone acetyltransferases to the viral promoter
    • Marzio, G.; Tyagi, M.; Gutierrez, M.I.; Giacca, M. HIV-1 tat transactivator recruits p300 and CREB-binding protein histone acetyltransferases to the viral promoter. Proc. Natl. Acad. Sci. USA 1998, 95, 13519-13524.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 13519-13524
    • Marzio, G.1    Tyagi, M.2    Gutierrez, M.I.3    Giacca, M.4
  • 20
    • 0033929108 scopus 로고    scopus 로고
    • The human factors YY1 and LSF repress the human immunodeficiency virus type 1 long terminal repeat via recruitment of histone deacetylase 1
    • Coull, J.J.; Romerio, F.; Sun, J.M.; Volker, J.L.; Galvin, K.M.; Davie, J.R.; Shi, Y.; Hansen, U.; Margolis, D.M. The human factors YY1 and LSF repress the human immunodeficiency virus type 1 long terminal repeat via recruitment of histone deacetylase 1. J. Virol. 2000, 74, 6790-6799.
    • (2000) J. Virol. , vol.74 , pp. 6790-6799
    • Coull, J.J.1    Romerio, F.2    Sun, J.M.3    Volker, J.L.4    Galvin, K.M.5    Davie, J.R.6    Shi, Y.7    Hansen, U.8    Margolis, D.M.9
  • 21
    • 30444431914 scopus 로고    scopus 로고
    • NF-kappaB p50 promotes HIV latency through HDAC recruitment and repression of transcriptional initiation
    • Williams, S.A.; Chen, L.F.; Kwon, H.; Ruiz-Jarabo, C.M.; Verdin, E.; Greene, W.C. NF-kappaB p50 promotes HIV latency through HDAC recruitment and repression of transcriptional initiation. EMBO J. 2006, 25, 139-149.
    • (2006) EMBO J. , vol.25 , pp. 139-149
    • Williams, S.A.1    Chen, L.F.2    Kwon, H.3    Ruiz-Jarabo, C.M.4    Verdin, E.5    Greene, W.C.6
  • 22
    • 33744952170 scopus 로고    scopus 로고
    • Transcriptional repression of human immunodeficiency virus type 1 by AP-4
    • Imai, K.; Okamoto, T. Transcriptional repression of human immunodeficiency virus type 1 by AP-4. J. Biol. Chem. 2006, 281, 12495-12505.
    • (2006) J. Biol. Chem. , vol.281 , pp. 12495-12505
    • Imai, K.1    Okamoto, T.2
  • 23
    • 37149031062 scopus 로고    scopus 로고
    • CBF-1 promotes transcriptional silencing during the establishment of HIV-1 latency
    • Tyagi, M.; Karn, J. CBF-1 promotes transcriptional silencing during the establishment of HIV-1 latency. EMBO J. 2007, 26, 4985-4995.
    • (2007) EMBO J. , vol.26 , pp. 4985-4995
    • Tyagi, M.1    Karn, J.2
  • 24
    • 35148858784 scopus 로고    scopus 로고
    • c-Myc and Sp1 contribute to proviral latency by recruiting histone deacetylase 1 to the human immunodeficiency virus type 1 promoter
    • Jiang, G.; Espeseth, A.; Hazuda, D.J.; Margolis, D.M. c-Myc and Sp1 contribute to proviral latency by recruiting histone deacetylase 1 to the human immunodeficiency virus type 1 promoter. J. Virol. 2007, 81, 10914-10923.
    • (2007) J. Virol. , vol.81 , pp. 10914-10923
    • Jiang, G.1    Espeseth, A.2    Hazuda, D.J.3    Margolis, D.M.4
  • 25
    • 0029919356 scopus 로고    scopus 로고
    • Transcriptional activation and chromatin remodeling of the HIV-1 promoter in response to histone acetylation
    • Van Lint, C.; Emiliani, S.; Ott, M.; Verdin, E. Transcriptional activation and chromatin remodeling of the HIV-1 promoter in response to histone acetylation. EMBO J. 1996, 15, 1112-1120.
    • (1996) EMBO J. , vol.15 , pp. 1112-1120
    • van Lint, C.1    Emiliani, S.2    Ott, M.3    Verdin, E.4
  • 27
  • 28
    • 0035958946 scopus 로고    scopus 로고
    • The histone acetyltransferase, hGCN5, interacts with and acetylates the HIV transactivator, Tat
    • Col, E.; Caron, C.; Seigneurin-Berny, D.; Gracia, J.; Favier, A.; Khochbin, S. The histone acetyltransferase, hGCN5, interacts with and acetylates the HIV transactivator, Tat. J. Biol. Chem. 2001, 276, 28179-28184.
    • (2001) J. Biol. Chem. , vol.276 , pp. 28179-28184
    • Col, E.1    Caron, C.2    Seigneurin-Berny, D.3    Gracia, J.4    Favier, A.5    Khochbin, S.6
  • 29
    • 0037151085 scopus 로고    scopus 로고
    • Tat acetyl-acceptor lysines are important for human immunodeficiency virus type-1 replication
    • Bres, V.; Kiernan, R.; Emiliani, S.; Benkirane, M. Tat acetyl-acceptor lysines are important for human immunodeficiency virus type-1 replication. J. Biol. Chem. 2002, 277, 22215-22221.
    • (2002) J. Biol. Chem. , vol.277 , pp. 22215-22221
    • Bres, V.1    Kiernan, R.2    Emiliani, S.3    Benkirane, M.4
  • 32
    • 79953203531 scopus 로고    scopus 로고
    • Regulation of Tat acetylation and transactivation activity by the microtubule-associated deacetylase HDAC6
    • Huo, L.; Li, D.; Sun, X.; Shi, X.; Karna, P.; Yang, W.; Liu, M.; Qiao, W.; Aneja, R.; Zhou, J. Regulation of Tat acetylation and transactivation activity by the microtubule-associated deacetylase HDAC6. J. Biol. Chem. 2011, 286, 9280-9286.
    • (2011) J. Biol. Chem. , vol.286 , pp. 9280-9286
    • Huo, L.1    Li, D.2    Sun, X.3    Shi, X.4    Karna, P.5    Yang, W.6    Liu, M.7    Qiao, W.8    Aneja, R.9    Zhou, J.10
  • 35
    • 0036776455 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 (HIV-1) accessory protein Vpr induces transcription of the HIV-1 and glucocorticoid-responsive promoters by binding directly to p300/CBP coactivators
    • Kino, T.; Gragerov, A.; Slobodskaya, O.; Tsopanomichalou, M.; Chrousos, G.P.; Pavlakis, G.N. Human immunodeficiency virus type 1 (HIV-1) accessory protein Vpr induces transcription of the HIV-1 and glucocorticoid-responsive promoters by binding directly to p300/CBP coactivators. J. Virol. 2002, 76, 9724-9734.
    • (2002) J. Virol. , vol.76 , pp. 9724-9734
    • Kino, T.1    Gragerov, A.2    Slobodskaya, O.3    Tsopanomichalou, M.4    Chrousos, G.P.5    Pavlakis, G.N.6
  • 36
    • 34547864553 scopus 로고    scopus 로고
    • Distinct GCN5/PCAF-containing complexes function as co-activators and are involved in transcription factor and global histone acetylation
    • Nagy, Z.; Tora, L. Distinct GCN5/PCAF-containing complexes function as co-activators and are involved in transcription factor and global histone acetylation. Oncogene 2007, 26, 5341-5357.
    • (2007) Oncogene , vol.26 , pp. 5341-5357
    • Nagy, Z.1    Tora, L.2
  • 38
    • 62549135623 scopus 로고    scopus 로고
    • Tat acetylation modulates assembly of a viral-host RNA-protein transcription complex
    • D'Orso, I.; Frankel, A.D. Tat acetylation modulates assembly of a viral-host RNA-protein transcription complex. Proc. Natl. Acad. Sci. USA 2009, 106, 3101-3106.
    • (2009) Proc. Natl. Acad. Sci. USA , vol.106 , pp. 3101-3106
    • D'Orso, I.1    Frankel, A.D.2
  • 39
    • 0037013851 scopus 로고    scopus 로고
    • Transcriptional synergy between Tat and PCAF is dependent on the binding of acetylated Tat to the PCAF bromodomain
    • Dorr, A.; Kiermer, V.; Pedal, A.; Rackwitz, H.R.; Henklein, P.; Schubert, U.; Zhou, M.M.; Verdin, E.; Ott, M. Transcriptional synergy between Tat and PCAF is dependent on the binding of acetylated Tat to the PCAF bromodomain. EMBO J. 2002, 21, 2715-2723.
    • (2002) EMBO J. , vol.21 , pp. 2715-2723
    • Dorr, A.1    Kiermer, V.2    Pedal, A.3    Rackwitz, H.R.4    Henklein, P.5    Schubert, U.6    Zhou, M.M.7    Verdin, E.8    Ott, M.9
  • 41
  • 42
    • 82455219436 scopus 로고    scopus 로고
    • Repressive LTR nucleosome positioning by the BAF complex is required for HIV latency
    • Rafati, H.; Parra, M.; Hakre, S.; Moshkin, Y.; Verdin, E.; Mahmoudi, T. Repressive LTR nucleosome positioning by the BAF complex is required for HIV latency. PLoS Biol. 2011, 9, e1001206.
    • (2011) PLoS Biol. , vol.9
    • Rafati, H.1    Parra, M.2    Hakre, S.3    Moshkin, Y.4    Verdin, E.5    Mahmoudi, T.6
  • 43
    • 84864098869 scopus 로고    scopus 로고
    • The BAF complex and HIV latency
    • Mahmoudi, T. The BAF complex and HIV latency. Transcription 2012, 3, 171-176.
    • (2012) Transcription , vol.3 , pp. 171-176
    • Mahmoudi, T.1
  • 45
    • 33746021681 scopus 로고    scopus 로고
    • The SWI/SNF chromatin-remodeling complex is a cofactor for Tat transactivation of the HIV promoter
    • Mahmoudi, T.; Parra, M.; Vries, R.G.; Kauder, S.E.; Verrijzer, C.P.; Ott, M.; Verdin, E. The SWI/SNF chromatin-remodeling complex is a cofactor for Tat transactivation of the HIV promoter. J. Biol. Chem. 2006, 281, 19960-19968.
    • (2006) J. Biol. Chem. , vol.281 , pp. 19960-19968
    • Mahmoudi, T.1    Parra, M.2    Vries, R.G.3    Kauder, S.E.4    Verrijzer, C.P.5    Ott, M.6    Verdin, E.7
  • 46
    • 33646130853 scopus 로고    scopus 로고
    • Requirement for SWI/SNF chromatin-remodeling complex in Tat-mediated activation of the HIV-1 promoter
    • Treand, C.; du Chene, I.; Bres, V.; Kiernan, R.; Benarous, R.; Benkirane, M.; Emiliani, S. Requirement for SWI/SNF chromatin-remodeling complex in Tat-mediated activation of the HIV-1 promoter. EMBO J. 2006, 25, 1690-1699.
    • (2006) EMBO J. , vol.25 , pp. 1690-1699
    • Treand, C.1    du Chene, I.2    Bres, V.3    Kiernan, R.4    Benarous, R.5    Benkirane, M.6    Emiliani, S.7
  • 48
    • 0041806599 scopus 로고    scopus 로고
    • The double bromodomain protein Brd4 binds to acetylated chromatin during interphase and mitosis
    • Dey, A.; Chitsaz, F.; Abbasi, A.; Misteli, T.; Ozato, K. The double bromodomain protein Brd4 binds to acetylated chromatin during interphase and mitosis. Proc. Natl. Acad. Sci. USA 2003, 100, 8758-8763.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 8758-8763
    • Dey, A.1    Chitsaz, F.2    Abbasi, A.3    Misteli, T.4    Ozato, K.5
  • 49
    • 34250357662 scopus 로고    scopus 로고
    • The double bromodomain-containing chromatin adaptor Brd4 and transcriptional regulation
    • Wu, S.Y.; Chiang, C.M. The double bromodomain-containing chromatin adaptor Brd4 and transcriptional regulation. J. Biol. Chem. 2007, 282, 13141-13145.
    • (2007) J. Biol. Chem. , vol.282 , pp. 13141-13145
    • Wu, S.Y.1    Chiang, C.M.2
  • 51
    • 35348816030 scopus 로고    scopus 로고
    • Conserved P-TEFb-interacting domain of BRD4 inhibits HIV transcription
    • Bisgrove, D.A.; Mahmoudi, T.; Henklein, P.; Verdin, E. Conserved P-TEFb-interacting domain of BRD4 inhibits HIV transcription. Proc. Natl. Acad. Sci. USA 2007, 104, 13690-13695.
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 13690-13695
    • Bisgrove, D.A.1    Mahmoudi, T.2    Henklein, P.3    Verdin, E.4
  • 52
    • 84862911038 scopus 로고    scopus 로고
    • Two-pronged binding with bromodomain-containing protein 4 liberates positive transcription elongation factor b from inactive ribonucleoprotein complexes
    • Schroder, S.; Cho, S.; Zeng, L.; Zhang, Q.; Kaehlcke, K.; Mak, L.; Lau, J.; Bisgrove, D.; Schnolzer, M.; Verdin, E.; et al. Two-pronged binding with bromodomain-containing protein 4 liberates positive transcription elongation factor b from inactive ribonucleoprotein complexes. J. Biol. Chem. 2012, 287, 1090-1099.
    • (2012) J. Biol. Chem. , vol.287 , pp. 1090-1099
    • Schroder, S.1    Cho, S.2    Zeng, L.3    Zhang, Q.4    Kaehlcke, K.5    Mak, L.6    Lau, J.7    Bisgrove, D.8    Schnolzer, M.9    Verdin, E.10
  • 53
    • 0035891271 scopus 로고    scopus 로고
    • The 7SK small nuclear RNA inhibits the CDK9/cyclin T1 kinase to control transcription
    • Yang, Z.; Zhu, Q.; Luo, K.; Zhou, Q. The 7SK small nuclear RNA inhibits the CDK9/cyclin T1 kinase to control transcription. Nature 2001, 414, 317-322.
    • (2001) Nature , vol.414 , pp. 317-322
    • Yang, Z.1    Zhu, Q.2    Luo, K.3    Zhou, Q.4
  • 54
    • 23744467035 scopus 로고    scopus 로고
    • Recruitment of P-TEFb for stimulation of transcriptional elongation by the bromodomain protein Brd4
    • Yang, Z.; Yik, J.H.; Chen, R.; He, N.; Jang, M.K.; Ozato, K.; Zhou, Q. Recruitment of P-TEFb for stimulation of transcriptional elongation by the bromodomain protein Brd4. Mol. Cell 2005, 19, 535-545.
    • (2005) Mol. Cell , vol.19 , pp. 535-545
    • Yang, Z.1    Yik, J.H.2    Chen, R.3    He, N.4    Jang, M.K.5    Ozato, K.6    Zhou, Q.7
  • 55
    • 58149487612 scopus 로고    scopus 로고
    • Bromodomain protein Brd4 regulates human immunodeficiency virus transcription through phosphorylation of CDK9 at threonine 29
    • Zhou, M.; Huang, K.; Jung, K.J.; Cho, W.K.; Klase, Z.; Kashanchi, F.; Pise-Masison, C.A.; Brady, J.N. Bromodomain protein Brd4 regulates human immunodeficiency virus transcription through phosphorylation of CDK9 at threonine 29. J. Virol. 2009, 83, 1036-1044.
    • (2009) J. Virol. , vol.83 , pp. 1036-1044
    • Zhou, M.1    Huang, K.2    Jung, K.J.3    Cho, W.K.4    Klase, Z.5    Kashanchi, F.6    Pise-Masison, C.A.7    Brady, J.N.8
  • 56
    • 67349221027 scopus 로고    scopus 로고
    • Acetylation of cyclin T1 regulates the equilibrium between active and inactive P-TEFb in cells
    • Cho, S.; Schroeder, S.; Kaehlcke, K.; Kwon, H.S.; Pedal, A.; Herker, E.; Schnoelzer, M.; Ott, M. Acetylation of cyclin T1 regulates the equilibrium between active and inactive P-TEFb in cells. EMBO J. 2009, 28, 1407-1417.
    • (2009) EMBO J. , vol.28 , pp. 1407-1417
    • Cho, S.1    Schroeder, S.2    Kaehlcke, K.3    Kwon, H.S.4    Pedal, A.5    Herker, E.6    Schnoelzer, M.7    Ott, M.8
  • 57
    • 73649124584 scopus 로고    scopus 로고
    • Structures of the dual bromodomains of the P-TEFbactivating protein Brd4 at atomic resolution
    • Vollmuth, F.; Blankenfeldt, W.; Geyer, M. Structures of the dual bromodomains of the P-TEFbactivating protein Brd4 at atomic resolution. J. Biol. Chem. 2009, 284, 36547-36556.
    • (2009) J. Biol. Chem. , vol.284 , pp. 36547-36556
    • Vollmuth, F.1    Blankenfeldt, W.2    Geyer, M.3
  • 60
    • 84855226549 scopus 로고    scopus 로고
    • Identification of cellular factors binding to acetylated HIV-1 integrase
    • Allouch, A.; Cereseto, A. Identification of cellular factors binding to acetylated HIV-1 integrase. Amino Acids 2011, 41, 1137-1145.
    • (2011) Amino Acids , vol.41 , pp. 1137-1145
    • Allouch, A.1    Cereseto, A.2
  • 61
    • 0034717183 scopus 로고    scopus 로고
    • Structure and function of a human TAFII250 double bromodomain module
    • Jacobson, R.H.; Ladurner, A.G.; King, D.S.; Tjian, R. Structure and function of a human TAFII250 double bromodomain module. Science 2000, 288, 1422-1425.
    • (2000) Science , vol.288 , pp. 1422-1425
    • Jacobson, R.H.1    Ladurner, A.G.2    King, D.S.3    Tjian, R.4
  • 64
    • 0029831827 scopus 로고    scopus 로고
    • Identification and characterization of a leukocyte-specific component of the nuclear body
    • Bloch, D.B.; de la Monte, S.M.; Guigaouri, P.; Filippov, A.; Bloch, K.D. Identification and characterization of a leukocyte-specific component of the nuclear body. J. Biol. Chem. 1996, 271, 29198-29204.
    • (1996) J. Biol. Chem. , vol.271 , pp. 29198-29204
    • Bloch, D.B.1    de la Monte, S.M.2    Guigaouri, P.3    Filippov, A.4    Bloch, K.D.5
  • 65
    • 0029845262 scopus 로고    scopus 로고
    • LYSP100-associated nuclear domains (LANDs): Description of a new class of subnuclear structures and their relationship to PML nuclear bodies
    • Dent, A.L.; Yewdell, J.; Puvion-Dutilleul, F.; Koken, M.H.; de The, H.; Staudt, L.M. LYSP100-associated nuclear domains (LANDs): Description of a new class of subnuclear structures and their relationship to PML nuclear bodies. Blood 1996, 88, 1423-1426.
    • (1996) Blood , vol.88 , pp. 1423-1426
    • Dent, A.L.1    Yewdell, J.2    Puvion-Dutilleul, F.3    Koken, M.H.4    de The, H.5    Staudt, L.M.6
  • 66
    • 0036839055 scopus 로고    scopus 로고
    • Implication of the lymphocyte-specific nuclear body protein Sp140 in an innate response to human immunodeficiency virus type 1
    • Madani, N.; Millette, R.; Platt, E.J.; Marin, M.; Kozak, S.L.; Bloch, D.B.; Kabat, D. Implication of the lymphocyte-specific nuclear body protein Sp140 in an innate response to human immunodeficiency virus type 1. J. Virol. 2002, 76, 11133-11138.
    • (2002) J. Virol. , vol.76 , pp. 11133-11138
    • Madani, N.1    Millette, R.2    Platt, E.J.3    Marin, M.4    Kozak, S.L.5    Bloch, D.B.6    Kabat, D.7
  • 67
    • 0344413641 scopus 로고    scopus 로고
    • The antiretroviral enzyme APOBEC3G is degraded by the proteasome in response to HIV-1 Vif
    • Sheehy, A.M.; Gaddis, N.C.; Malim, M.H. The antiretroviral enzyme APOBEC3G is degraded by the proteasome in response to HIV-1 Vif. Nat. Med. 2003, 9, 1404-1407.
    • (2003) Nat. Med. , vol.9 , pp. 1404-1407
    • Sheehy, A.M.1    Gaddis, N.C.2    Malim, M.H.3
  • 70
    • 33644838910 scopus 로고    scopus 로고
    • Identification of transcription complexes that contain the double bromodomain protein Brd2 and chromatin remodeling machines
    • Denis, G.V.; McComb, M.E.; Faller, D.V.; Sinha, A.; Romesser, P.B.; Costello, C.E. Identification of transcription complexes that contain the double bromodomain protein Brd2 and chromatin remodeling machines. J. Proteome Res. 2006, 5, 502-511.
    • (2006) J. Proteome Res. , vol.5 , pp. 502-511
    • Denis, G.V.1    McComb, M.E.2    Faller, D.V.3    Sinha, A.4    Romesser, P.B.5    Costello, C.E.6
  • 72
    • 38549113034 scopus 로고    scopus 로고
    • Brd4 recruits P-TEFb to chromosomes at late mitosis to promote G1 gene expression and cell cycle progression
    • Yang, Z.; He, N.; Zhou, Q. Brd4 recruits P-TEFb to chromosomes at late mitosis to promote G1 gene expression and cell cycle progression. Mol. Cell. Biol. 2008, 28, 967-976.
    • (2008) Mol. Cell. Biol. , vol.28 , pp. 967-976
    • Yang, Z.1    He, N.2    Zhou, Q.3
  • 79
    • 84879317671 scopus 로고    scopus 로고
    • International Patent PCT/JP2008/073864 (US2010/0286127 A1), 26 December
    • Miyoshi, S.; Ooike, S.; Iwata, K.; Hikawa, H.; Sugahara, K. International Patent PCT/JP2008/073864 (US2010/0286127 A1), 26 December 2008.
    • (2008)
    • Miyoshi, S.1    Ooike, S.2    Iwata, K.3    Hikawa, H.4    Sugahara, K.5
  • 82
    • 84859424538 scopus 로고    scopus 로고
    • Valproic acid in association with highly active antiretroviral therapy for reducing systemic HIV-1 reservoirs: Results from a multicentre randomized clinical study
    • Routy, J.P.; Tremblay, C.L.; Angel, J.B.; Trottier, B.; Rouleau, D.; Baril, J.G.; Harris, M.; Trottier, S.; Singer, J.; Chomont, N.; et al. Valproic acid in association with highly active antiretroviral therapy for reducing systemic HIV-1 reservoirs: Results from a multicentre randomized clinical study. HIV Med. 2012, 13, 291-296.
    • (2012) HIV Med. , vol.13 , pp. 291-296
    • Routy, J.P.1    Tremblay, C.L.2    Angel, J.B.3    Trottier, B.4    Rouleau, D.5    Baril, J.G.6    Harris, M.7    Trottier, S.8    Singer, J.9    Chomont, N.10
  • 84
    • 84867760525 scopus 로고    scopus 로고
    • Bromodomain and extra-terminal (BET) bromodomain inhibition activate transcription via transient release of positive transcription elongation factor b (P-TEFb) from 7SK small nuclear ribonucleoprotein
    • Bartholomeeusen, K.; Xiang, Y.; Fujinaga, K.; Peterlin, B.M. Bromodomain and extra-terminal (BET) bromodomain inhibition activate transcription via transient release of positive transcription elongation factor b (P-TEFb) from 7SK small nuclear ribonucleoprotein. J. Biol. Chem. 2012, 287, 36609-36616.
    • (2012) J. Biol. Chem. , vol.287 , pp. 36609-36616
    • Bartholomeeusen, K.1    Xiang, Y.2    Fujinaga, K.3    Peterlin, B.M.4
  • 85
    • 84871725205 scopus 로고    scopus 로고
    • The BET bromodomain inhibitor JQ1 activates HIV latency through antagonizing Brd4 inhibition of Tat-transactivation
    • Li, Z.; Guo, J.; Wu, Y.; Zhou, Q. The BET bromodomain inhibitor JQ1 activates HIV latency through antagonizing Brd4 inhibition of Tat-transactivation. Nucleic Acids Res. 2013, 41, 277-287.
    • (2013) Nucleic Acids Res. , vol.41 , pp. 277-287
    • Li, Z.1    Guo, J.2    Wu, Y.3    Zhou, Q.4


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