Two-pronged binding with bromodomain-containing protein 4 liberates positive transcription elongation factor b from inactive ribonucleoprotein complexes

Journal of Biological Chemistry

Volumn 287, Issue 2, 2012, Pages 1090-1099

  Schröder, Sebastian ^a   Cho, Sungyoo ^a,b   Zeng, Lei ^c   Zhang, Qiang ^c   Kaehlcke, Katrin ^a   Mak, Lily ^a   Lau, Joann ^a   Bisgrove, Dwayne ^a,e   Schnölzer, Martina ^d   Verdin, Eric ^a,b   Zhou, Ming Ming ^c   Ott, Melanie ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^d GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^e Clontech Laboratories   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CORE COMPONENTS; CYCLIN T1; DATA SUPPORT; NUCLEAR RIBONUCLEOPROTEIN; OVER-EXPRESSION; POSITIVE TRANSCRIPTION ELONGATION FACTOR B; RIBONUCLEOPROTEIN COMPLEX; SPLICE VARIANTS; TRANSCRIPTIONAL ACTIVATIONS;

AMINO ACIDS; GENES;

TRANSCRIPTION;

BROMODOMAIN CONTAINING PROTEIN 4; CARBOXY TERMINAL TELOPEPTIDE; CYCLIN DEPENDENT KINASE 9; CYCLIN T1; MEDIATOR COMPLEX; POSITIVE TRANSCRIPTION ELONGATION FACTOR B; RIBONUCLEOPROTEIN; SMALL NUCLEAR RNA; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; SPLICEOSOME; TRANSCRIPTION INITIATION;

CYCLIN T; CYCLIN-DEPENDENT KINASE 9; HELA CELLS; HIV LONG TERMINAL REPEAT; HUMANS; NUCLEAR PROTEINS; POSITIVE TRANSCRIPTIONAL ELONGATION FACTOR B; PROTEIN STRUCTURE, TERTIARY; RIBONUCLEOPROTEINS; RNA-BINDING PROTEINS; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

EID: 84862911038     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.282855     Document Type: Article

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