The DNAJB6 and DNAJB8 protein chaperones prevent intracellular aggregation of polyglutamine peptides

Journal of Biological Chemistry

Volumn 288, Issue 24, 2013, Pages 17225-17237

  Gillis, Judith ^a   Schipper Krom, Sabine ^a   Juenemann, Katrin ^a   Gruber, Anna ^a   Coolen, Silvia ^a   Van Den Nieuwendijk, Rian ^b   Van Veen, Henk ^a   Overkleeft, Hermen ^b   Goedhart, Joachim ^b   Kampinga, Harm H ^c   Reits, Eric A ^a  

^a ACADEMIC MEDICAL CENTER   (Netherlands)

^b LEIDEN UNIVERSITY   (Netherlands)

^c UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

AGGREGATE FORMATION; HUNTINGTON'S DISEASE; INTRACELLULAR PROTEINS; PEPTIDE AGGREGATION; POLYGLUTAMINE (POLYQ); PROTEIN AGGREGATION; PROTEIN CHAPERONE; PROTEIN FRAGMENTS;

NEURODEGENERATIVE DISEASES;

PEPTIDES;

CHAPERONE; HEAT SHOCK PROTEIN 70; POLYGLUTAMINE; PROTEIN DNAJB1; PROTEIN DNAJB6; PROTEIN DNAJB8; UNCLASSIFIED DRUG;

ARTICLE; CELL NUCLEUS; CONTROLLED STUDY; CYTOPLASM; HUMAN; HUMAN CELL; IN VITRO STUDY; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN BINDING; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN PURIFICATION;

CONFOCAL MICROSCOPY; DNAJB; HUNTINGTON'S DISEASE; MOLECULAR CHAPERONE; PEPTIDES; POLYGLUTAMINE DISEASE;

CELL NUCLEUS; CYTOPLASM; HEK293 CELLS; HELA CELLS; HSP40 HEAT-SHOCK PROTEINS; HUMANS; MOLECULAR CHAPERONES; NERVE TISSUE PROTEINS; PEPTIDE FRAGMENTS; PEPTIDES; PROTEIN BINDING; PROTEIN MULTIMERIZATION; SOLUBILITY;

EID: 84879067006     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.421685     Document Type: Article

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