α-synuclein oligomers with broken helical conformation form lipoprotein nanoparticles

Journal of Biological Chemistry

Volumn 288, Issue 24, 2013, Pages 17620-17630

  Varkey, Jobin ^a   Mizuno, Naoko ^b,d   Hegde, Balachandra G ^c   Cheng, Naiqian ^d   Steven, Alasdair C ^d   Langen, Ralf ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

^c PES UNIVERSITY   (India)

^d NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CRYO-ELECTRON MICROSCOPY; DOUBLE ELECTRON-ELECTRON RESONANCE; FATTY ACID TRANSPORT; HELICAL CONFORMATION; MITOCHONDRIAL MEMBRANES; NANOPARTICLE FORMATION; PHOSPHATIDYLGLYCEROLS; SEQUENCE SIMILARITY;

CELL MEMBRANES; ELECTRON MICROSCOPES; FATTY ACIDS; LIPOPROTEINS; MITOCHONDRIA; OLIGOMERS;

NANOPARTICLES;

ALPHA SYNUCLEIN; FATTY ACID; LIPID; LIPOPOROTEIN NANOPARTICLE; NANOPARTICLE; UNCLASSIFIED DRUG;

ALPHA HELIX; AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CIRCULAR DICHROISM; CONTROLLED STUDY; CRYOELECTRON MICROSCOPY; FATTY ACID TRANSPORT; LIGHT SCATTERING; MEMBRANE BINDING; OLIGOMERIZATION; PHOSPHOLIPID MEMBRANE; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN FUNCTION; PROTEIN LIPID INTERACTION; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS;

Α-SYNUCLEIN; ELECTRON MICROSCOPY (EM); ELECTRON PARAMAGNETIC RESONANCE (EPR); MEMBRANE PROTEINS; NANOPARTICLES; NEURODEGENERATIVE DISEASES;

ALPHA-SYNUCLEIN; CHOLESTEROL; CHROMATOGRAPHY, GEL; CRYOELECTRON MICROSCOPY; FLUORESCENCE RESONANCE ENERGY TRANSFER; HUMANS; LIPOPROTEINS; MEMBRANES, ARTIFICIAL; MITOCHONDRIAL MEMBRANES; NANOPARTICLES; PARTICLE SIZE; PHOSPHATIDYLCHOLINES; PHOSPHATIDYLGLYCEROLS; PHOSPHATIDYLSERINES; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, SECONDARY;

EID: 84879066759     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.476697     Document Type: Article

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