Structure and dynamics of micelle-bound human α-synuclein

Journal of Biological Chemistry

Volumn 280, Issue 10, 2005, Pages 9595-9603

  Ulmer, Tobias S ^a   Bax, Ad ^a   Cole, Nelson B ^b   Nussbaum, Robert L ^b  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^b NATIONAL HUMAN GENOME RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BIOCHEMISTRY; DISEASES; LIPIDS; MICELLES; MOLECULAR BIOLOGY; MOLECULAR STRUCTURE;

INTERHELICAL DISTANCE; LIPIDIC SURFACES; MISFOLDING; PARKINSON'S DISEASE; PRESYNAPTIC VESICLES;

PROTEINS;

ALANINE; ALPHA SYNUCLEIN; ASPARTIC ACID; GLYCINE; LYSINE; THREONINE; VALINE;

ALPHA HELIX; ARTICLE; AUTOPHAGY; CELL MEMBRANE; CONTROLLED STUDY; MICELLE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN LIPID INTERACTION; PROTON NUCLEAR MAGNETIC RESONANCE; SYNAPSE VESICLE;

ALPHA-SYNUCLEIN; AMINO ACID SEQUENCE; BINDING SITES; DETERGENTS; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MICELLES; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NERVE TISSUE PROTEINS; PHOSPHOPROTEINS; PROTEIN STRUCTURE, SECONDARY; SODIUM DODECYL SULFATE; SYNUCLEINS;

EID: 15744362063     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M411805200     Document Type: Article

References (70)

1. Goedert, M. (2001) Nat. Rev. Neurosci. 2, 492-501
2. Dev, K. K., Hofele, K., Barbieri, S., Buchman, V. L., and van der Putten, H. (2003) Neuropharmacology 45, 14-44
3. Nussbaum, R. L., and Ellis, C. E. (2003) N. Engl. J. Med. 348, 1356-1364
4. Spillantini, M. G., Schmidt, M. L., Lee, V. M. Y., Trojanowski, J. Q., Jakes, R., and Goedert, M. (1997) Nature 388, 839-840
5. Mezey, E., Dehejia, A. M., Harta, G., Suchy, S. F., Nussbaum, R. L., Brownstein, M. J., and Polymeropoulos, M. H. (1998) Mol. Psychiatry 3, 493-499
6. Conway, K. A., Lee, S. J., Rochet, J. C., Ding, T. T., Williamson, R. E., and Lansbury, P. T. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 571-576
7. Fernandez, C. O., Hoyer, W., Zweckstetter, M., Jares-Erijman, E. A., Subramaniam, V., Griesinger, C., and Jovin, T. M. (2004) EMBO J. 23, 2039-2046
8. Kahle, P. J., Haass, C., Kretzschmar, H. A., and Neumann, M. (2002) J. Neurochem. 82, 449-457
9. Vekrellis, K., Rideout, H. J., and Stefanis, L. (2004) Mol. Neurobiol. 30, 1-21
10. Davidson, W. S., Jonas, A., Clayton, D. F., and George, J. M. (1998) J. Biol. Chem. 273, 9443-9449
11. George, J. M., Jin, H., Woods, W. S., and Clayton, D. F. (1995) Neuron 15, 361-372
12. Chandra, S., Chen, X. C., Rizo, J., Jahn, R., and Sudhof, T. C. (2003) J. Biol. Chem. 278, 15313-15318
13. Eliezer, D., Kutluay, E., Bussell, R., and Browne, G. (2001) J. Mol. Biol. 307, 1061-1073
14. Narayanan, V., and Scarlata, S. (2001) Biochemistry 40, 9927-9934
15. Jensen, P. H., Nielsen, M. S., Jakes, R., Dotti, G., and Goedert, M. (1998) J. Biol. Chem. 273, 26292-26294
16. Iwai, A., Masliah, E., Yoshimoto, M., Ge, N. F., Flanagan, L., Desilva, H. A. R., Kittel, A., and Saitoh, T. (1995) Neuron 14, 467-475
17. Weinreb, P. H., Zhen, W. G., Poon, A. W., Conway, K. A., and Lansbury, P. T. (1996) Biochemistry 35, 13709-13715
18. Bussell, R., and Eliezer, D. (2003) J. Mol. Biol. 329, 763-778
19. Jao, C. C., Der-Sarkissian, A., Chen, J., and Langen, R. (2004) Proc. Natl. Acad. Sci. U. S. A. 101, 8331-8336
20. Der-Sarkissian, A., Jao, C. C., Chen, J., and Langen, R. (2003) J. Biol. Chem. 278, 37530-37535
21. Cole, N. B., Murphy, D. D., Grider, T., Rueter, S., Brasaemle, D., and Nussbaum, R. L. (2002) J. Biol. Chem. 277, 6344-6352
22. Lee, H. J., Choi, C., and Lee, S. J. (2002) J. Biol. Chem. 277, 671-678
23. Goto, N. K., Gardner, K. H., Mueller, G. A., Willis, R. C., and Kay, L. E. (1999) J. Biomol. NMR 13, 369-374
24. Ulmer, T. S., Ramirez, B. E., Delaglio, F., and Bax, A. (2003) J. Am. Chem. Soc. 125, 9179-9191
25. Chou, J. J., Gaemers, S., Howder, B., Louis, J. M., and Bax, A. (2001) J. Biomol. NMR 21, 377-382
26. Delaglio, F., Grzesiek, S., Vuister, G. W., Zhu, G., Pfeifer, J., and Bax, A. (1995) J. Biomol. NMR 6, 277-293
27. Pervushin, K., Riek, R., Wider, G., and Wuthrich, K. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 12366-12371
28. Weigelt, J. (1998) J. Am. Chem. Soc. 120, 10778-10779
29. Grzesiek, S., Anglister, J., and Bax, A. (1993) J. Magn. Reson. Ser. B 101, 114-119
30. Hu, J. S., and Bax, A. (1997) J. Biomol. NMR 9, 323-328
31. Hu, J. S., Grzesiek, S., and Bax, A. (1997) J. Am. Chem. Soc. 119, 1803-1804
32. Jaroniec, C. P., Ulmer, T. S., and Bax, A. (2004) J. Biomol. NMR 30, 181-194
33. Chou, J. J., Delaglio, F., and Bax, A. (2000) J. Biomol. NMR 18, 101-105
34. Zhu, G., Xia, Y. L., Nicholson, L. K., and Sze, K. H. (2000) J. Magn. Reson. 143, 423-426
35. Farrow, N. A., Muhandiram, R., Singer, A. U., Pascal, S. M., Kay, C. M., Gish, G., Shoelson, S. E., Pawson, T., Formankay, J. D., and Kay, L. E. (1994) Biochemistry 33, 5984-6003
36. Donaldson, L. W., Skrynnikov, N. R., Choy, W. Y., Muhandiram, D. R., Sarkar, B., Forman-Kay, J. D., and Kay, L. E. (2001) J. Am. Chem. Soc. 123, 9843-9847
37. Delaglio, F., Kontaxis, G., and Bax, A. (2000) J. Am. Chem. Soc. 122, 2142-2143
38. Schwieters, C. D., Kuszewski, J. J., Tjandra, N., and Clore, G. M. (2003) J. Magn. Reson. 160, 65-73
39. Iwahara, J., Schwieters, C. D., and Clore, G. M. (2004) J. Am. Chem. Soc. 126, 5879-5896
40. Grishaev, A., and Bax, A. (2004) J. Am. Chem. Soc. 126, 7281-7292
41. Kuszewski, J. J., and Clore, G. M. (2000) J. Magn. Reson. 146, 249-254
42. Tycko, R., Blanco, F. J., and Ishii, Y. (2000) J. Am. Chem. Soc. 122, 9340-9341
43. Bertini, I., Luchinat, C., and Piccioli, M. (2001) Methods Enzymol. 339, 314-340
44. Kumar, S., and Bansal, M. (1998) Biophys. J. 75, 1935-1944
45. Bansal, M., Kumar, S., and Velavan, R. (2000) J. Biomol. Struct. Dyn. 17, 811-819
46. Lipari, G., and Szabo, A. (1982) J. Am. Chem. Soc. 104, 4546-4559
47. Meiler, J., Prompers, J. J., Peti, W., Griesinger, C., and Bruschweiler, R. (2001) J. Am. Chem. Soc. 123, 6098-6107
48. Tolman, J. R., Al-Hashimi, H. M., Kay, L. E., and Prestegard, J. H. (2001) J. Am. Chem. Soc. 123, 1416-1424
49. Oldfield, E. (2002) Annu. Rev. Phys. Chem. 53, 349-378
50. Case, D. A. (1998) Curr. Opin. Struc. Biol. 8, 624-630
51. Rehage, H., and Hoffmann, H. (1991) Mol. Phys. 74, 933-973
52. Bruce, C. D., Berkowitz, M. L., Perera, L., and Forbes, M. D. E. (2002) J. Phys. Chem. B 106, 3788-3793
53. Garg, G., Aswal, V. K., Kulshreshtha, S. K., and Haasan, P. A. (2004) Pramana J. Phys. 63, 351-355
54. Shortle, D., and Ackerman, M. S. (2001) Science 293, 487-489
55. Louhivuori, M., Fredriksson, K., Paakkonen, K., Permi, P., and Annila, A. (2004) J. Biomol. NMR 29, 517-524
56. Zhang, B., Koh, Y. H., Beckstead, R. B., Budnik, V., Ganetzky, B., and Bellen, H. J. (1998) Neuron 21, 1465-1475
57. Phillips, G. R., Huang, J. K., Wang, Y., Tanaka, H., Shapiro, L., Zhang, W. D., Shan, W. S., Arndt, K., Frank, M., Gordon, R. E., Gawinowicz, M. A., Zhao, Y. M., and Colman, D. R. (2001) Neuron 32, 63-77
58. Cuervo, A. M., Stefanis, L., Fredenburg, R., Lansbury, P. T., and Sulzer, D. (2004) Science 305, 1292-1295
59. Curran, A. R., and Engelman, D. M. (2003) Curr. Opin. Struct. Biol. 13, 412-417
60. Ramakrishnan, M., Jensen, P. H., and Marsh, D. (2003) Biochemistry 42, 12919-12926
61. Nuscher, B., Kamp, F., Mehnert, T., Odoy, S., Haass, C., Kahle, P. J., and Beyer, K. (2004) J. Biol. Chem. 279, 21966-21975
62. Sharon, R., Bar-Joseph, I., Mirick, G. E., Serhan, C. N., and Selkoe, D. J. (2003) J. Biol. Chem. 278, 49874-49881
63. Jo, E., Darabie, A. A., Han, K., Tandon, A., Fraser, P. E., and McLaurin, J. (2004) Eur. J. Biochem. 271, 3180-3189
64. Segrest, J. P., Deloof, H., Dohlman, J. G., Brouillette, C. G., and Anantharamaiah, G. M. (1990) Proteins 8, 103-117
65. Kruger, R., Kuhn, W., Muller, T., Woitalla, D., Graeber, M., Kosel, S., Przuntek, H., Epplen, J. T., Schols, L., and Riess, O. (1998) Nat. Genet. 18, 106-108
66. Anderson, C. A. F., Palmer, A. G., Brunak, S., and Rost, B. (2002) Structure 10, 175-184
67. Dosset, P., Hus, J. C., Blackledge, M., and Marion, D. (2000) J. Biomol. NMR 16, 23-28
68. Sklenar, V. (1995) J. Magn. Reson. Ser. A 114, 132-135
69. Spera, S., and Bax, A. (1991) J. Am. Chem. Soc. 113, 5490-5492
70. Baker, N. A., Sept, D., Joseph, S., Holst, M. J., and McCammon, J. A. (2001) P. Natl. Acad. Sci. U. S. A. 98, 10037-10041