Structural organization of α-synuclein fibrils studied by site-directed spin labeling

Journal of Biological Chemistry

Volumn 278, Issue 39, 2003, Pages 37530-37535

  Der Sarkissiant, Ani ^a   Jao, Christine C ^b   Chen, Jeannie ^a,b   Langen, Ralf ^b  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; DISEASE CONTROL; ELECTRON SPIN RESONANCE SPECTROSCOPY; PARAMAGNETIC RESONANCE; POLYPEPTIDES;

FIBRILS;

PROTEINS;

ALPHA SYNUCLEIN; AMINO ACID; AMYLOID BETA PROTEIN; MONOMER;

AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; ELECTRON SPIN RESONANCE; FIBER; GENETIC CONSERVATION; NONHUMAN; PARKINSON DISEASE; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN ASSEMBLY; PROTEIN FOLDING; PROTEIN STRUCTURE; SPIN LABELING;

ALPHA-SYNUCLEIN; AMYLOID BETA-PROTEIN; ELECTRON SPIN RESONANCE SPECTROSCOPY; HUMANS; MODELS, MOLECULAR; NERVE TISSUE PROTEINS; PROTEIN FOLDING; SYNUCLEINS;

EID: 0141733169     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M305266200     Document Type: Article

References (47)

1. Spillantini, M. G., Schmidt, M. L., Lee, V. M., Trojanowski, J. Q., Jakes, R., and Goedert, M. (1997) Nature 388, 839-840
2. Polymeropoulos, M. H., Lavedan, C., Leroy, E., Ide, S. E., Dehejia, A., Dutra, A., Pike, B., Root, H., Rubenstein, J., Boyer, R., Stenroos, E. S., Chandrasekharappa, S., Athanassiadou, A., Papapetropoulos, T., Johnson, W. G., Lazzarini, A. M., Duvoisin, R. C., Di Iorio, G., Golbe, L. I., and Nussbaum, R. L. (1997) Science 276, 2045-2047
3. Kruger, R., Kuhn, W., Muller, T., Woitalla, D., Graeber, M., Kosel, S., Przuntek, H., Epplen, J. T., Schols, L., and Riess, O. (1998) Nat. Genet. 18, 106-108
4. Feany, M. B., and Bender, W. W. (2000) Nature 404, 394-398
5. Masliah, E., Rockenstein, E., Veinbergs, I., Mallory, M., Hashimoto, M., Takeda, A., Sagara, Y., Sisk, A., and Mucke, L. (2000) Science 287, 1265-1269
6. van der Putten, H., Wiederhold, K. H., Probst, A., Barbieri, S., Mistl, C., Danner, S., Kauffmann, S., Hofele, K., Spooren, W. P., Ruegg, M. A., Lin, S., Caroni, P., Sommer, B., Tolnay, M., and Bilbe, G. (2000) J. Neurosci. 20, 6021-6029
7. Kim, T. D., Ryu, H. J., Cho, H. I., Yang, C. H., and Kim, J. (2000) Biochemistry 39, 14839-14846
8. Weinreb, P. H., Zhen, W., Poon, A. W., Conway, K. A., and Lansbury, P. T., Jr. (1996) Biochemistry 35, 13709-13715
9. Iwai, A., Masliah, E., Yoshimoto, M., Ge, N., Flanagan, L., de Silva, H. A., Kittel, A., and Saitoh, T. (1995) Neuron 14, 467-475
10. Maroteaux, L., and Scheller, R. H. (1991) Brain Res. Mol. Brain Res, 11, 335-343
11. Murray, I. V., Lee, V. M.-Y., and Trojanowski, J. Q. (2001) Clin. Neurosci. Res. 1, 445-455
12. Serpell, L. C., Berriman, J., Jakes, R., Goedert, M., and Crowther, R. A. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 4897-4902
13. Conway, K. A., Harper, J. D., and Lansbury, P. T., Jr. (2000) Biochemistry 39, 2552-2563
14. Ueda, K., Fukushima, H., Masliah, E., Xia, Y., Iwai, A., Yoshimoto, M., Otero, D. A., Kondo, J., Ihara, Y., and Saitoh, T. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 11282-11286
15. Iwai, A., Yoshimoto, M., Masliah, E., and Saitoh, T. (1995) Biochemistry 34, 10139-10145
16. Giasson, B. I., Murray, I. V., Trojanowski, J. Q., and Lee, V. M. (2001) J. Biol. Chem. 276, 2380-2386
17. Jakes, R., Spillantini, M. G., and Goedert, M. (1994) FEBS Lett. 345, 27-32
18. Biere, A. L., Wood, S. J., Wypych, J., Steavenson, S., Jiang, Y., Anafi, D., Jacobsen, F. W., Jarosinski, M. A., Wu, G. M., Louis, J. C., Martin, F., Narhi, L. O., and Citron, M. (2000) J. Biol. Chem. 275, 34574-34579
19. Miake, H., Mizusawa, H., Iwatsubo, T., and Hasegawa, M. (2002) J. Biol. Chem. 277, 19213-19219
20. Hubbell, W. L., Cafiso, D. S., and Altenbach, C. (2000) Nat. Struct. Biol. 7, 735-739
21. Török, M., Milton, S., Kayed, R., Wu, P., McIntire, T., Glabe, C. G., and Langen, R. (2002) J. Biol. Chem. 277, 40810-40815
22. Serag, A. A., Altenbach, C., Gingery, M., Hubbell, W. L., and Yeates, T. O. (2001) Biochemistry 40, 9089-9096
23. Margittai, M., Fasshauer, D., Pabst, S., Jahn, R., and Langen, R. (2001) J. Biol. Chem. 276, 13169-13177
24. Isas, J. M., Langen, R., Haigler, H. T., and Hubbell, W. L. (2002) Biochemistry 41, 1464-1473
25. Mchaourab, H. S., Lietzow, M. A., Hideg, K., and Hubbell, W. L. (1996) Biochemistry 35, 7692-7704
26. Hubbell, W. L., Froncisz, W., and Hyde, J. S. (1987) Rev. Sci. Instrum. 58, 1879-1886
27. Hustedt, E. J., Smirnov, A. I., Laub, C, F., Cobb, C. E., and Beth, A. H. (1997) Biophys. J. 72, 1861-1877
28. Mchaourab, H. S., Oh, K. J., Fang, C. J., and Hubbell, W. L. (1997) Biochemistry 36, 307-316
29. Rabenstein, M. D., and Shin, Y. K. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 8239-8243
30. Steinhoff, H. J., Radzwill, N., Thevis, W., Lenz, V., Brandenburg, D., Antson, A., Dodson, G., and Wollmer, A. (1997) Biophys. J. 73, 3287-3298
31. Altenbach, C., Oh, K. J., Trabanino, R. J., Hideg, K., and Hubbell, W. L. (2001) Biochemistry 40, 15471-15482
32. El-Agnaf, O. M., Jakes, R., Curran, M. D., Middleton, D., Ingenito, R., Bianchi, E., Pessi, A., Neill, D., and Wallace, A. (1998) FEBS Lett. 440, 71-75
33. Han, H., Weinreb, P. H., and Lansbury, P. T., Jr. (1995) Chem. Biol. 2, 163-169
34. Kheterpal, I., Williams, A., Murphy, C., Bledsoe, B., and Wetzel, R. (2001) Biochemistry 40, 11757-11767
35. Tycko, R. (2003) Biochemistry 42, 3151-3159
36. Lansbury, P. T., Jr. (1997) Neuron 19, 1151-1154
37. Makin, O. S., and Serpell, L. C. (2002) Biochem. Soc. Trans. 30, 521-525
38. Soto, C. (2003) Nat. Rev. Neurosci. 4, 49-60
39. O'Nuallain, B., and Wetzel, R. (2002) Proc. Natl. Acad. Sci. U. S. A. 99, 1485-1490
40. Kayed, R., Head, E., Thompson, J. L., McIntire, T. M., Milton, S. C., Cotman, C. W., and Glabe, C. G. (2003) Science 300, 486-489
41. Crowther, R. A., Jakes, R., Spillantini, M. G., and Goedert, M. (1998) FEBS Lett. 436, 309-312
42. Baba, M., Nakajo, S., Tu, P. H., Tomita, T., Nakaya, K., Lee, V. M., Trojanowski, J. Q., and Iwatsubo, T. (1998) Am. J. Pathol. 152, 879-884
43. Uversky, V. N., Li, J., and Fink, A. L. (2001) J. Biol. Chem. 276, 10737-10744
44. Narhi, L., Wood, S. J., Steavenson, S., Jiang, Y., Wu, G. M., Anafi, D., Kaufman, S. A., Martin, F., Sitney, K., Denis, P., Louis, J. C., Wypych, J., Biere, A, L., and Citron, M. (1999) J. Biol. Chem. 274, 9843-9846
45. Fraser, P. E., Nguyen, J. T., Inouye, H., Surewicz, W. K., Selkoe, D. J., Podlisny, M. B., and Kirschner, D. A. (1992) Biochemistry 31, 10716-10723
46. Hilbich, C., Kisters-Woike, B., Reed, J., Masters, C. L., and Beyreuther, K. (1991) J. Mol. Biol. 218, 149-163
47. Petkova, A. T., Ishii, Y., Balbach, J. J., Antzutkin, O. N., Leapman, R. D., Delaglio, F., and Tycko, R. (2002) Proc. Natl. Acad. Sci. U. S. A. 99, 16742-16747