Altered Fatty Acid Composition of Dopaminergic Neurons Expressing α-Synuclein and Human Brains with α-Synucleinopathies

Journal of Biological Chemistry

Volumn 278, Issue 50, 2003, Pages 49874-49881

  Sharon, Ronit ^a   Bar Joseph, Ifat ^a   Mirick, Gudrun E ^b   Serhan, Charles N ^b   Selkoe, Dennis J ^a,b  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN; CELLS; DISEASES; NEUROLOGY; OLIGOMERS; PROTEINS;

NEURONS;

FATTY ACIDS;

ALPHA SYNUCLEIN; NERVE PROTEIN;

ANIMAL CELL; ARTICLE; BRAIN TISSUE; DOPAMINERGIC NERVE CELL; GENE DELETION; GENE OVEREXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; LIPID COMPOSITION; MEMBRANE FLUIDITY; MESENCEPHALON; MOUSE; NONHUMAN; NULL ALLELE; OLIGOMERIZATION; PARKINSON DISEASE; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN EXPRESSION; SUPERNATANT;

ALPHA-SYNUCLEIN; ANIMALS; BRAIN; BRAIN CHEMISTRY; CELL MEMBRANE; CYTOSOL; DOPAMINE; FATTY ACIDS; FATTY ACIDS, UNSATURATED; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HUMANS; LEWY BODIES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MODELS, CHEMICAL; NERVE TISSUE PROTEINS; NEURODEGENERATIVE DISEASES; NEURONS; PROTEIN BINDING; SYNUCLEINS; TIME FACTORS; TRANSFECTION;

ANIMALIA;

EID: 0347379922     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M309127200     Document Type: Article

References (44)

1. George, J. M., Jin, H., Woods, W. S., and Clayton, D. F. (1995) Neuron 15, 361-372
2. Weinreb, P. H., Zhen, W., Poon, A. W., Conway, K. A., and Lansbury, P. T., Jr. (1996) Biochemistry 35, 13709-13715
3. Narhi, L., Wood, S. J., Steavenson, S., Jiang, Y., Wu, G. M., Anafi, D., Kaufman, S. A., Martin, F., Sitney, K., Denis, P., Louis, J. C., Wypych, J., Biere, A. L., and Citron, M. (1999) J. Biol. Chem. 274, 9843-9846
4. Conway, K. A., Lee, S. J., Rochet, J. C., Ding, T. T., Williamson, R. E., and Lansbury, P. T., Jr. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 571-576
5. Conway, K. A., Harper, J. D., and Lansbury, P. T. (1998) Nat. Med. 4, 1318-1320
6. Lee, H. J., Shin, S. Y., Choi, C., Lee, Y. H., and Lee, S. J. (2002) J. Biol. Chem. 277, 5411-5417
7. Kowall, N. W., Hantraye, P., Brouillet, E., Beal, M. F., McKee, A. C., and Ferrante, R. J. (2000) Neuroreport 11, 211-213
8. McNaught, K. S., Bjorklund, L. M., Belizaire, R., Isacson, O., Jenner, P., and Olanow, C. W. (2002) Neuroreport 13, 1437-1441
9. Tofaris, G. K., Layfield, R., and Spillantini, M. G. (2001) FEBS Lett. 509, 22-26
10. Paik, S. R., Shin, H. J., and Lee, J. H. (2000) Arch. Biochem. Biophys. 378, 269-277
11. Uversky, V. N., Li, J., and Fink, A. L. (2001) J. Biol. Chem. 276, 44284-44296
12. Paxinou, E., Chen, Q., Weisse, M., Giasson, B. I., Norris, E. H., Rueter, S. M., Trojanowski, J. Q., Lee, V. M., and Ischiropoulos, H. (2001) J. Neurosci. 21, 8053-8061
13. Kim, K. S., Choi, S. Y., Kwon, H. Y., Won, M. H., Kang, T. C., and Kang, J. H. (2002) Free Radic. Biol. Med. 32, 544-550
14. Fujiwara, H., Hasegawa, M., Dohmae, N., Kawashima, A., Masliah, E., Goldberg, M. S., Shen, J., Takio, K., and Iwatsubo, T. (2002) Nat. Cell Biol. 4, 160-164
15. Perrin, R. J., Woods, W. S., Clayton, D. F., and George, J. M. (2001) J. Biol. Chem. 276, 41958-41962
16. Sharon, R., Bar-Joseph, I., Frosch, M. P., Walsh, D. M., Hamilton, J. A., and Selkoe, D. J. (2003) Neuron 37, 583-595
17. Sharon, R., Goldberg, M. S., Bar-Josef, I., Betensky, R. A., Shen, J., and Selkoe, D. J. (2001) Proc. Natl. Acad. Sci. U. S. A. 98, 9110-9115
18. Gronert, K., Martinsson-Niskanen, T., Ravasi, S., Chiang, N., and Serhan, C. N. (2001) Am. J. Pathol. 158, 3-9
19. Mostofsky, D. I., Yehuda, S., and Salem, N. J. (2001) in Fatty Acids Physiological and Behavioral Functions (Bendich, A., ed) Humana Press, Totowa, New Jersey
20. Yehuda, S., Rabinovitz, S., Carasso, R. L., and Mostofsky, D. I. (2002) Neurobiol. Aging 23, 843-853
21. Youdim, K. A., Martin, A., and Joseph, J. A. (2000) Int. J. Dev. Neurosci. 18, 383-399
22. McLean, P. J., Kawamata, H., Ribich, S., and Hyman, B. T. (2000) J. Biol. Chem. 275, 8812-8816
23. Kahle, P. J., Neumann, M., Ozmen, L., Muller, V., Jacobsen, H., Schindzielorz, A., Okochi, M., Leimer, U., van der Putten, H., Probst, A., Kremmer, E., Kretzschmar, H. A., and Haass, C. (2000) J. Neurosci. 20, 6365-6373
24. Jensen, P. H., Nielsen, M. S., Jakes, R., Dotti, C. G., and Goedert, M. (1998) J. Biol. Chem. 273, 26292-26294
25. Stubbs, C. D., and Smith, A. D. (1990) Biochem. Soc. Trans. 18, 779-781
26. McMurchie, E. J. (1998) in Physiological Regulation of Membrane Fluidity (Aloia, R. C., ed) Alan R. Liss, New York
27. Mouritsen, O. G., and Bloom, M. (1993) Annu. Rev. Biophys. Biomol. Struct. 22, 145-171
28. Poschl, J. M., Paul, K., Leichsenring, M., Han, S. R., Pfisterer, M., Bremer, H. J., and Linderkamp, O. (1999) Lipids 34, 467-473
29. Williams, E. E., Cooper, J. A., Stillwell, W., and Jenski, L. J. (2000) Mol. Membr. Biol. 17, 157-164
30. Zimmer, L., Delpal, S., Guilloteau, D., Aioun, J., Durand, G., and Chalon, S. (2000) Neurosci. Lett. 284, 25-28
31. Zimmer, L., Delion, S., Vancassel, S., Durand, G., Guilloteau, D., Bodard, S., and Chalon, S. (2000) J. Lipid Res. 41, 32-40
32. Owens, S. P., and Innis, S. M. (1998) J. Nutr. 129
33. Delion, S., Chalon, S., Guilloteau, D., Besnard, J. C., and Durand, G. (1996) J. Neurochem. 66, 1582-1591
34. Delion, S., Chalon, S., Guilloteau, D., Besnard, J. C., and Durand, G. (1994) J. Nutr. 124, 2466-2476
35. Chalon, S., Delion, S., Vancassel, S., Belzung, C., Guilloteau, D., and Leguiesquet, A. M. (1998) J. Nutr. 128, 2512-2519
36. Cabin, D. E., Shimazu, K., Murphy, D., Cole, N. B., Gottschalk, W., McIlwain, K. L., Orrison, B., Chen, A., Ellis, C. E., Paylor, R., Lu, B., and Nussbaum, R. L. (2002) J. Neurosci. 22, 8797-8807
37. Murphy, D. D., Rueter, S. M., Trojanowski, J. Q., and Lee, V. M. (2000) J. Neurosci. 20, 3214-3220
38. Halliwell, B. (2001) Drugs Aging 18, 685-716
39. Fahn, S., and Cohen, G. (1992) Ann. Neurol. 32, 804-812
40. Halliwell, B. (1992) J. Neurochem. 59, 1609-1623
41. Jenner, P., Schapira, A. H., and Marsden, C. D. (1992) Neurology 42, 2241-2250
42. Jenner, P. (1991) Acta Neurol. Scand Suppl. 136, 6-15
43. Braunbeck, T., and Volkl, A. (1991) Ecotoxicol. Environ. Saf. 21, 109-127
44. Halliwell, B., and Gutteridge, J. M. C. (2000) Free Radicals in Biology and Medicine, 3rd Ed., Oxford University Press, Oxford, UK