LKB1 represses Focal Adhesion Kinase (FAK) signaling via a FAK-LKB1 complex to regulate FAK site maturation and directional persistence

Journal of Biological Chemistry

Volumn 288, Issue 24, 2013, Pages 17663-17674

  Kline, Erik R ^a   Shupe, John ^a   Gilbert Ross, Melissa ^a   Zhou, Wei ^a   Marcus, Adam I ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADHESION DYNAMICS; ADHESION SIGNALING; C-TERMINAL DOMAINS; ENHANCED ADHESIONS; FOCAL ADHESION KINASE; MULTIPLE CELLULAR FUNCTIONS; N-TERMINAL DOMAINS; PROTEOMIC STUDIES;

ADHESION; AMINO ACIDS; CELLS; CYTOLOGY; ENZYMES; SIGNALING;

CELL SIGNALING;

CELL PROTEIN; FIBRONECTIN; FOCAL ADHESION KINASE; PROEIN STRAD ALPHA; PROTEIN KINASE LKB1; TYROSINE; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; CELL ADHESION; CELL MIGRATION; CELL MOTILITY; COMPLEX FORMATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; ENZYME REGULATION; ENZYME REPRESSION; ENZYME STABILITY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION;

ADHESION; CELL MIGRATION; CELL MOTILITY; EPITHELIAL MESENCHYMAL TRANSITION; FOCAL ADHESION KINASE; IMAGING; LKB1;

CELL ADHESION; CELL LINE, TUMOR; CELL MOVEMENT; CELL POLARITY; FOCAL ADHESION KINASE 1; FOCAL ADHESIONS; GENE KNOCKDOWN TECHNIQUES; HUMANS; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN MULTIMERIZATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN-SERINE-THREONINE KINASES; QUINOLONES; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; SINGLE-CELL ANALYSIS; SULFONES;

MURINAE;

EID: 84879050733     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.444620     Document Type: Article

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