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Volumn 32, Issue 16, 2012, Pages 3203-3217

AMPK regulates mitotic spindle orientation through phosphorylation of myosin regulatory light chain

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE KINASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; MYOSIN LIGHT CHAIN; MYOSIN REGULATORY LIGHT CHAIN; PROTEIN KINASE LKB1; SERINE; THREONINE; UNCLASSIFIED DRUG;

EID: 84865115634     PISSN: 02707306     EISSN: 10985549     Source Type: Journal    
DOI: 10.1128/MCB.00418-12     Document Type: Article
Times cited : (62)

References (50)
  • 1
    • 72449131381 scopus 로고    scopus 로고
    • CaMKK is an upstream signal of AMP-activated protein kinase in regulation of substrate metabolism in contracting skeletal muscle
    • Abbott MJ, Edelman AM, Turcotte LP. 2009. CaMKK is an upstream signal of AMP-activated protein kinase in regulation of substrate metabolism in contracting skeletal muscle. Am. J. Physiol. Regul. Integr. Comp. Physiol. 297:R1724-R1732.
    • (2009) Am. J. Physiol. Regul. Integr. Comp. Physiol. , vol.297
    • Abbott, M.J.1    Edelman, A.M.2    Turcotte, L.P.3
  • 2
    • 54649083796 scopus 로고    scopus 로고
    • Spindle positioning in mouse oocytes relies on a dynamic meshwork of actin filaments
    • Azoury J, et al. 2008. Spindle positioning in mouse oocytes relies on a dynamic meshwork of actin filaments. Curr. Biol. 18:1514-1519.
    • (2008) Curr. Biol. , vol.18 , pp. 1514-1519
    • Azoury, J.1
  • 3
    • 84355161919 scopus 로고    scopus 로고
    • Chemical genetic screen for AMPKalpha2 substrates uncovers a network of proteins involved in mitosis
    • Banko MR, et al. 2011. Chemical genetic screen for AMPKalpha2 substrates uncovers a network of proteins involved in mitosis. Mol. Cell 44:878-892.
    • (2011) Mol. Cell , vol.44 , pp. 878-892
    • Banko, M.R.1
  • 4
    • 57749198014 scopus 로고    scopus 로고
    • Myosin light chains are not a physiological substrate of AMPK in the control of cell structure changes
    • Bultot L, et al. 2009. Myosin light chains are not a physiological substrate of AMPK in the control of cell structure changes. FEBS Lett. 583:25-28.
    • (2009) FEBS Lett , vol.583 , pp. 25-28
    • Bultot, L.1
  • 5
    • 35649027944 scopus 로고    scopus 로고
    • Versatile fluorescent probes for actin filaments based on the actin-binding domain of utrophin
    • Burkel BM, von Dassow G, Bement WM. 2007. Versatile fluorescent probes for actin filaments based on the actin-binding domain of utrophin. Cell Motil. Cytoskeleton 64:822-832.
    • (2007) Cell Motil. Cytoskeleton , vol.64 , pp. 822-832
    • Burkel, B.M.1    von Dassow, G.2    Bement, W.M.3
  • 6
    • 0025346733 scopus 로고
    • Attachment of one spindle pole to the cortex in unequal cleavage
    • Dan K, Tanaka Y. 1990. Attachment of one spindle pole to the cortex in unequal cleavage. Ann. N. Y. Acad. Sci. 582:108-119.
    • (1990) Ann. N. Y. Acad. Sci. , vol.582 , pp. 108-119
    • Dan, K.1    Tanaka, Y.2
  • 7
    • 84861541297 scopus 로고    scopus 로고
    • STE20-regulated kinase adaptor protein alpha (STRADalpha) regulates cell polarity and invasion through PAK1 signaling in LKB1 null cells
    • Eggers CM, Kline ER, Zhong D, Zhou W, Marcus AI. 2012. STE20-regulated kinase adaptor protein alpha (STRADalpha) regulates cell polarity and invasion through PAK1 signaling in LKB1 null cells. J. Biol. Chem., 287:18758-18768.
    • (2012) J. Biol. Chem. , vol.287 , pp. 18758-18768
    • Eggers, C.M.1    Kline, E.R.2    Zhong, D.3    Zhou, W.4    Marcus, A.I.5
  • 8
    • 0037933457 scopus 로고    scopus 로고
    • Cell biology. Microtubule asymmetry
    • Gundersen GG, Bretscher A. 2003. Cell biology. Microtubule asymmetry. Science 300:2040-2041.
    • (2003) Science , vol.300 , pp. 2040-2041
    • Gundersen, G.G.1    Bretscher, A.2
  • 9
    • 34648828532 scopus 로고    scopus 로고
    • AMP-activated/SNF1 protein kinases: conserved guardians of cellular energy
    • Hardie DG. 2007. AMP-activated/SNF1 protein kinases: conserved guardians of cellular energy. Nat. Rev. Mol. Cell Biol. 8:774-785.
    • (2007) Nat. Rev. Mol. Cell Biol. , vol.8 , pp. 774-785
    • Hardie, D.G.1
  • 10
    • 77950868813 scopus 로고    scopus 로고
    • Jasplakinolide: an actin-specific reagent that promotes actin polymerization
    • Holzinger A. 2009. Jasplakinolide: an actin-specific reagent that promotes actin polymerization. Methods Mol. Biol. 586:71-87.
    • (2009) Methods Mol. Biol. , vol.586 , pp. 71-87
    • Holzinger, A.1
  • 12
    • 20444468520 scopus 로고    scopus 로고
    • Function of mammalian LKB1 and Ca2+/calmodulin-dependent protein kinase kinase alpha as Snf1-activating kinases in yeast
    • Hong SP, Momcilovic M, Carlson M. 2005. Function of mammalian LKB1 and Ca2+/calmodulin-dependent protein kinase kinase alpha as Snf1-activating kinases in yeast. J. Biol. Chem. 280:21804-21809.
    • (2005) J. Biol. Chem. , vol.280 , pp. 21804-21809
    • Hong, S.P.1    Momcilovic, M.2    Carlson, M.3
  • 13
    • 34247603071 scopus 로고    scopus 로고
    • Possible CaMKK-dependent regulation of AMPK phosphorylation and glucose uptake at the onset of mild tetanic skeletal muscle contraction
    • Jensen TE, et al. 2007. Possible CaMKK-dependent regulation of AMPK phosphorylation and glucose uptake at the onset of mild tetanic skeletal muscle contraction. Am. J. Physiol. Endocrinol. Metab. 292:E1308-E1317.
    • (2007) Am. J. Physiol. Endocrinol. Metab. , vol.292
    • Jensen, T.E.1
  • 14
    • 63449127363 scopus 로고    scopus 로고
    • The actin cytoskeleton in spindle assembly and positioning
    • Kunda P, Baum B. 2009. The actin cytoskeleton in spindle assembly and positioning. Trends Cell Biol. 19:174-179.
    • (2009) Trends Cell Biol , vol.19 , pp. 174-179
    • Kunda, P.1    Baum, B.2
  • 15
    • 38349022141 scopus 로고    scopus 로고
    • Moesin controls cortical rigidity, cell rounding, and spindle morphogenesis during mitosis
    • Kunda P, Pelling AE, Liu T, Baum B. 2008. Moesin controls cortical rigidity, cell rounding, and spindle morphogenesis during mitosis. Curr. Biol. 18:91-101.
    • (2008) Curr. Biol. , vol.18 , pp. 91-101
    • Kunda, P.1    Pelling, A.E.2    Liu, T.3    Baum, B.4
  • 16
    • 34250827107 scopus 로고    scopus 로고
    • Energy-dependent regulation of cell structure by AMP-activated protein kinase
    • Lee JH, et al. 2007. Energy-dependent regulation of cell structure by AMP-activated protein kinase. Nature 447:1017-1020.
    • (2007) Nature , vol.447 , pp. 1017-1020
    • Lee, J.H.1
  • 17
    • 21744445075 scopus 로고    scopus 로고
    • Regulation of myosin II during cytokinesis in higher eukaryotes
    • Matsumura F. 2005. Regulation of myosin II during cytokinesis in higher eukaryotes. Trends Cell Biol. 15:371-377.
    • (2005) Trends Cell Biol , vol.15 , pp. 371-377
    • Matsumura, F.1
  • 18
    • 0031917782 scopus 로고    scopus 로고
    • Specific localization of serine 19 phosphorylated myosin II during cell locomotion and mitosis of cultured cells
    • Matsumura F, Ono S, Yamakita Y, Totsukawa G, Yamashiro S. 1998. Specific localization of serine 19 phosphorylated myosin II during cell locomotion and mitosis of cultured cells. J. Cell Biol. 140:119-129.
    • (1998) J. Cell Biol. , vol.140 , pp. 119-129
    • Matsumura, F.1    Ono, S.2    Yamakita, Y.3    Totsukawa, G.4    Yamashiro, S.5
  • 19
    • 77249121152 scopus 로고    scopus 로고
    • Homozygous deletion of the STK11/LKB1 locus and the generation of novel fusion transcripts in cervical cancer cells
    • McCabe MT, Powell DR, Zhou W, Vertino PM. 2010. Homozygous deletion of the STK11/LKB1 locus and the generation of novel fusion transcripts in cervical cancer cells. Cancer Genet. Cytogenet. 197:130-141.
    • (2010) Cancer Genet. Cytogenet. , vol.197 , pp. 130-141
    • McCabe, M.T.1    Powell, D.R.2    Zhou, W.3    Vertino, P.M.4
  • 20
    • 78049488876 scopus 로고    scopus 로고
    • Revolving movement of a dynamic cluster of actin filaments during mitosis
    • Mitsushima M, et al. 2010. Revolving movement of a dynamic cluster of actin filaments during mitosis. J. Cell Biol. 191:453-462.
    • (2010) J. Cell Biol. , vol.191 , pp. 453-462
    • Mitsushima, M.1
  • 21
    • 0036800381 scopus 로고    scopus 로고
    • Astral microtubules monitor metaphase spindle alignment in fission yeast
    • Oliferenko S, Balasubramanian MK. 2002. Astral microtubules monitor metaphase spindle alignment in fission yeast. Nat. Cell Biol. 4:816-820.
    • (2002) Nat. Cell Biol. , vol.4 , pp. 816-820
    • Oliferenko, S.1    Balasubramanian, M.K.2
  • 23
    • 0026781163 scopus 로고
    • Role of astral microtubules and actin in spindle orientation and migration in the budding yeast. Saccharomyces cerevisiae
    • Palmer RE, Sullivan DS, Huffaker T, Koshland D. 1992. Role of astral microtubules and actin in spindle orientation and migration in the budding yeast, Saccharomyces cerevisiae. J. Cell Biol. 119:583-593.
    • (1992) J. Cell Biol. , vol.119 , pp. 583-593
    • Palmer, R.E.1    Sullivan, D.S.2    Huffaker, T.3    Koshland, D.4
  • 24
    • 79953156769 scopus 로고    scopus 로고
    • Mitotic spindle misorientation in cancer-out of alignment and into the fire
    • Pease JC, Tirnauer JS. 2011. Mitotic spindle misorientation in cancer-out of alignment and into the fire. J. Cell Sci. 124:1007-1016.
    • (2011) J. Cell Sci. , vol.124 , pp. 1007-1016
    • Pease, J.C.1    Tirnauer, J.S.2
  • 25
    • 14744285013 scopus 로고    scopus 로고
    • Spindle assembly: asters part their separate ways
    • Rosenblatt J. 2005. Spindle assembly: asters part their separate ways. Nat. Cell Biol. 7:219-222.
    • (2005) Nat. Cell Biol. , vol.7 , pp. 219-222
    • Rosenblatt, J.1
  • 26
    • 2042544799 scopus 로고    scopus 로고
    • Myosin II- dependent cortical movement is required for centrosome separation and positioning during mitotic spindle assembly
    • Rosenblatt J, Cramer LP, Baum B, McGee KM. 2004. Myosin II- dependent cortical movement is required for centrosome separation and positioning during mitotic spindle assembly. Cell 117:361-372.
    • (2004) Cell , vol.117 , pp. 361-372
    • Rosenblatt, J.1    Cramer, L.P.2    Baum, B.3    McGee, K.M.4
  • 27
    • 34147152841 scopus 로고    scopus 로고
    • Investigating the mechanism for AMP activation of the AMP-activated protein kinase cascade
    • Sanders MJ, Grondin PO, Hegarty BD, Snowden MA, Carling D. 2007. Investigating the mechanism for AMP activation of the AMP-activated protein kinase cascade. Biochem. J. 403:139-148.
    • (2007) Biochem. J. , vol.403 , pp. 139-148
    • Sanders, M.J.1    Grondin, P.O.2    Hegarty, B.D.3    Snowden, M.A.4    Carling, D.5
  • 28
    • 34248170746 scopus 로고    scopus 로고
    • Farnesyl transferase inhibitors impair chromosomal maintenance in cell lines and human tumors by compromising CENP-E and CENP-F function
    • Schafer-Hales K, et al. 2007. Farnesyl transferase inhibitors impair chromosomal maintenance in cell lines and human tumors by compromising CENP-E and CENP-F function. Mol. Cancer Ther. 6:1317-1328.
    • (2007) Mol. Cancer Ther. , vol.6 , pp. 1317-1328
    • Schafer-Hales, K.1
  • 29
    • 0034677906 scopus 로고    scopus 로고
    • Myosins: a diverse superfamily
    • Sellers JR. 2000. Myosins: a diverse superfamily. Biochim. Biophys. Acta 1496:3-22.
    • (2000) Biochim. Biophys. Acta , vol.1496 , pp. 3-22
    • Sellers, J.R.1
  • 30
    • 1542618348 scopus 로고    scopus 로고
    • The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress
    • Shaw RJ, et al. 2004. The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress. Proc. Natl. Acad. Sci. U. S. A. 101:3329-3335.
    • (2004) Proc. Natl. Acad. Sci. U. S. A. , vol.101 , pp. 3329-3335
    • Shaw, R.J.1
  • 31
    • 0032769705 scopus 로고    scopus 로고
    • Direct observation of microtubule-f-actin interaction in cell free lysates
    • Sider JR, et al. 1999. Direct observation of microtubule-f-actin interaction in cell free lysates. J. Cell Sci. 112(Pt 12):1947-1956.
    • (1999) J. Cell Sci. , vol.112 , Issue.PART 12 , pp. 1947-1956
    • Sider, J.R.1
  • 32
    • 0141751697 scopus 로고    scopus 로고
    • Ca2+ sensitivity of smooth muscle and nonmuscle myosin II: modulated by G proteins, kinases, and myosin phosphatase
    • Somlyo AP, Somlyo AV. 2003. Ca2+ sensitivity of smooth muscle and nonmuscle myosin II: modulated by G proteins, kinases, and myosin phosphatase. Physiol. Rev. 83:1325-1358.
    • (2003) Physiol. Rev. , vol.83 , pp. 1325-1358
    • Somlyo, A.P.1    Somlyo, A.V.2
  • 33
    • 13344285343 scopus 로고    scopus 로고
    • Mammalian AMP-activated protein kinase subfamily
    • Stapleton D, et al. 1996. Mammalian AMP-activated protein kinase subfamily. J. Biol. Chem. 271:611-614.
    • (1996) J. Biol. Chem. , vol.271 , pp. 611-614
    • Stapleton, D.1
  • 34
    • 33745823168 scopus 로고    scopus 로고
    • Regulation of the energy sensor AMP-activated protein kinase by antigen receptor and Ca2+ in T lymphocytes
    • Tamas P, et al. 2006. Regulation of the energy sensor AMP-activated protein kinase by antigen receptor and Ca2+ in T lymphocytes. J. Exp. Med. 203:1665-1670.
    • (2006) J. Exp. Med. , vol.203 , pp. 1665-1670
    • Tamas, P.1
  • 36
    • 33947596005 scopus 로고    scopus 로고
    • Integrin-mediated adhesion orients the spindle parallel to the substratum in an EB1- and myosin X-dependent manner
    • Toyoshima F, Nishida E. 2007. Integrin-mediated adhesion orients the spindle parallel to the substratum in an EB1- and myosin X-dependent manner. EMBO J. 26:1487-1498.
    • (2007) EMBO J , vol.26 , pp. 1487-1498
    • Toyoshima, F.1    Nishida, E.2
  • 37
    • 34848840325 scopus 로고    scopus 로고
    • Spindle orientation in animal cell mitosis: roles of integrin in the control of spindle axis
    • Toyoshima F, Nishida E. 2007. Spindle orientation in animal cell mitosis: roles of integrin in the control of spindle axis. J. Cell. Physiol. 213:407-411.
    • (2007) J. Cell. Physiol. , vol.213 , pp. 407-411
    • Toyoshima, F.1    Nishida, E.2
  • 38
    • 79953732149 scopus 로고    scopus 로고
    • A fluorescent reporter of AMPK activity and cellular energy stress
    • Tsou P, Zheng B, Hsu CH, Sasaki AT, Cantley LC. 2011. A fluorescent reporter of AMPK activity and cellular energy stress. Cell Metab. 13:476-486.
    • (2011) Cell Metab , vol.13 , pp. 476-486
    • Tsou, P.1    Zheng, B.2    Hsu, C.H.3    Sasaki, A.T.4    Cantley, L.C.5
  • 39
    • 62449138276 scopus 로고    scopus 로고
    • Mitotic kinase dynamics of the active form of AMPK (phospho-AMPKalphaThr172) in human cancer cells
    • Vazquez-Martin A, et al. 2009. Mitotic kinase dynamics of the active form of AMPK (phospho-AMPKalphaThr172) in human cancer cells. Cell Cycle 8:788-791.
    • (2009) Cell Cycle , vol.8 , pp. 788-791
    • Vazquez-Martin, A.1
  • 40
    • 79954529883 scopus 로고    scopus 로고
    • Polo-like kinase 1 regulates activation of AMP-activated protein kinase (AMPK) at the mitotic apparatus
    • Vazquez-Martin A, Oliveras-Ferraros C, Cufi S, Menendez JA. 2011. Polo-like kinase 1 regulates activation of AMP-activated protein kinase (AMPK) at the mitotic apparatus. Cell Cycle 10:1295-1302.
    • (2011) Cell Cycle , vol.10 , pp. 1295-1302
    • Vazquez-Martin, A.1    Oliveras-Ferraros, C.2    Cufi, S.3    Menendez, J.A.4
  • 42
    • 68449094064 scopus 로고    scopus 로고
    • The active form of the metabolic sensor: AMP-activated protein kinase (AMPK) directly binds the mitotic apparatus and travels from centrosomes to the spindle midzone during mitosis and cytokinesis
    • Vazquez-Martin A, Oliveras-Ferraros C, Menendez JA. 2009. The active form of the metabolic sensor: AMP-activated protein kinase (AMPK) directly binds the mitotic apparatus and travels from centrosomes to the spindle midzone during mitosis and cytokinesis. Cell Cycle 8:2385-2398.
    • (2009) Cell Cycle , vol.8 , pp. 2385-2398
    • Vazquez-Martin, A.1    Oliveras-Ferraros, C.2    Menendez, J.A.3
  • 44
    • 63449109391 scopus 로고    scopus 로고
    • Concurrent cues for cytokinetic furrow induction in animal cells
    • von Dassow G. 2009. Concurrent cues for cytokinetic furrow induction in animal cells. Trends Cell Biol. 19:165-173.
    • (2009) Trends Cell Biol , vol.19 , pp. 165-173
    • von Dassow, G.1
  • 45
    • 77952687450 scopus 로고    scopus 로고
    • Myosin II contributes to cell-scale actin network treadmilling through network disassembly
    • Wilson CA, et al. 2010. Myosin II contributes to cell-scale actin network treadmilling through network disassembly. Nature 465:373-377.
    • (2010) Nature , vol.465 , pp. 373-377
    • Wilson, C.A.1
  • 46
    • 23044437445 scopus 로고    scopus 로고
    • Ca2+/calmodulin-dependent protein kinase kinase-beta acts upstream of AMP-activated protein kinase in mammalian cells
    • Woods A, et al. 2005. Ca2+/calmodulin-dependent protein kinase kinase-beta acts upstream of AMP-activated protein kinase in mammalian cells. Cell Metab. 2:21-33.
    • (2005) Cell Metab , vol.2 , pp. 21-33
    • Woods, A.1
  • 47
    • 10744230065 scopus 로고    scopus 로고
    • LKB1 is the upstream kinase in the AMP-activated protein kinase cascade
    • Woods A, et al. 2003. LKB1 is the upstream kinase in the AMP-activated protein kinase cascade. Curr. Biol. 13:2004-2008.
    • (2003) Curr. Biol. , vol.13 , pp. 2004-2008
    • Woods, A.1
  • 48
    • 47549089279 scopus 로고    scopus 로고
    • Myosin-10 and actin filaments are essential for mitotic spindle function
    • Woolner S, O'Brien LL, Wiese C, Bement WM. 2008. Myosin-10 and actin filaments are essential for mitotic spindle function. J. Cell Biol. 182:77-88.
    • (2008) J. Cell Biol. , vol.182 , pp. 77-88
    • Woolner, S.1    O'Brien, L.L.2    Wiese, C.3    Bement, W.M.4
  • 49
    • 38849204971 scopus 로고    scopus 로고
    • The tumor suppressor LKB1 regulates lung cancer cell polarity by mediating cdc42 recruitment and activity
    • Zhang S, et al. 2008. The tumor suppressor LKB1 regulates lung cancer cell polarity by mediating cdc42 recruitment and activity. Cancer Res. 68:740-748.
    • (2008) Cancer Res , vol.68 , pp. 740-748
    • Zhang, S.1
  • 50
    • 0034773404 scopus 로고    scopus 로고
    • Role of AMP-activated protein kinase in mechanism of metformin action
    • Zhou G, et al. 2001. Role of AMP-activated protein kinase in mechanism of metformin action. J. Clin. Invest. 108:1167-1174.
    • (2001) J. Clin. Invest. , vol.108 , pp. 1167-1174
    • Zhou, G.1


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