Overexpression of HAb18G/CD147 promotes invasion and metastasis via α3β1 integrin mediated FAK-paxillin and FAK-PI3K-Ca2+ pathways

Cellular and Molecular Life Sciences

Volumn 65, Issue 18, 2008, Pages 2933-2942

  Tang, J ^a   Wu, Y M ^a   Zhao, P ^a   Yang, X M ^a   Jiang, J L ^a   Chen, Z N ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

HAb18G CD147; Hepatoma cells; Invasion; Metastasis; Signal pathways

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; CALCIUM; CD147 ANTIGEN; FOCAL ADHESION KINASE; MATRIX METALLOPROTEINASE; PAXILLIN; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PROTEIN ANTIBODY; VERY LATE ACTIVATION ANTIGEN 3; WORTMANNIN;

ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CELL ADHESION; CELL INVASION; CYTOSKELETON; DOWN REGULATION; ENZYME RELEASE; FOCAL ADHESION; GENE DELETION; GENE OVEREXPRESSION; HEPATOMA CELL; HUMAN; HUMAN CELL; METASTASIS; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANTIGENS, CD147; CALCIUM; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; CYTOSKELETON; FOCAL ADHESION PROTEIN-TYROSINE KINASES; FOCAL ADHESIONS; GENE SILENCING; HUMANS; INTEGRIN ALPHA3BETA1; LIVER NEOPLASMS; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; PAXILLIN;

EID: 52549106580     PISSN: 1420682X     EISSN: 15691632     Source Type: Journal    
DOI: 10.1007/s00018-008-8315-8     Document Type: Article

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