메뉴 건너뛰기




Volumn 11, Issue , 2010, Pages

LKB1 tumor suppressor protein regulates actin filament assembly through Rho and its exchange factor Dbl independently of kinase activity

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; ADAPTOR PROTEIN; EZRIN; GUANINE NUCLEOTIDE EXCHANGE FACTOR; PROTEIN KINASE LKB1; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; SMALL INTERFERING RNA; TUMOR SUPPRESSOR PROTEIN; CYTOSKELETON PROTEIN; DNA BINDING PROTEIN; PROTEIN SERINE THREONINE KINASE; STK11 PROTEIN, HUMAN; STRAD PROTEIN, HUMAN; TRANSCRIPTION FACTOR; VESICULAR TRANSPORT ADAPTOR PROTEIN; VEZF1 PROTEIN, HUMAN;

EID: 77957735280     PISSN: None     EISSN: 14712121     Source Type: Journal    
DOI: 10.1186/1471-2121-11-77     Document Type: Article
Times cited : (27)

References (22)
  • 2
    • 45549086246 scopus 로고    scopus 로고
    • LKB1 and lung cancer: more than the usual suspects
    • 10.1158/0008-5472.CAN-07-6620, 18483235
    • Shah U, Sharpless NE, Hayes DN. LKB1 and lung cancer: more than the usual suspects. Cancer Res 2008, 68(10):3562-3565. 10.1158/0008-5472.CAN-07-6620, 18483235.
    • (2008) Cancer Res , vol.68 , Issue.10 , pp. 3562-3565
    • Shah, U.1    Sharpless, N.E.2    Hayes, D.N.3
  • 3
    • 0033529838 scopus 로고    scopus 로고
    • Growth suppression by Lkb1 is mediated by a G(1) cell cycle arrest
    • 10.1073/pnas.96.16.9248, 17765, 10430928
    • Tiainen M, Ylikorkala A, Makela TP. Growth suppression by Lkb1 is mediated by a G(1) cell cycle arrest. Proc Natl Acad Sci USA 1999, 96(16):9248-9251. 10.1073/pnas.96.16.9248, 17765, 10430928.
    • (1999) Proc Natl Acad Sci USA , vol.96 , Issue.16 , pp. 9248-9251
    • Tiainen, M.1    Ylikorkala, A.2    Makela, T.P.3
  • 4
    • 33750619348 scopus 로고    scopus 로고
    • Glucose metabolism and cancer
    • 10.1016/j.ceb.2006.10.005, 17046224
    • Shaw RJ. Glucose metabolism and cancer. Curr Opin Cell Biol 2006, 18(6):598-608. 10.1016/j.ceb.2006.10.005, 17046224.
    • (2006) Curr Opin Cell Biol , vol.18 , Issue.6 , pp. 598-608
    • Shaw, R.J.1
  • 5
    • 34250827107 scopus 로고    scopus 로고
    • Energy-dependent regulation of cell structure by AMP-activated protein kinase
    • 10.1038/nature05828, 17486097
    • Lee JH, Koh H, Kim M, Kim Y, Lee SY, Karess RE, Lee SH, Shong M, Kim JM, Kim J, et al. Energy-dependent regulation of cell structure by AMP-activated protein kinase. Nature 2007, 447(7147):1017-1020. 10.1038/nature05828, 17486097.
    • (2007) Nature , vol.447 , Issue.7147 , pp. 1017-1020
    • Lee, J.H.1    Koh, H.2    Kim, M.3    Kim, Y.4    Lee, S.Y.5    Karess, R.E.6    Lee, S.H.7    Shong, M.8    Kim, J.M.9    Kim, J.10
  • 6
    • 34248185949 scopus 로고    scopus 로고
    • LKB1 and AMPK maintain epithelial cell polarity under energetic stress
    • 10.1083/jcb.200702053, 2064817, 17470638
    • Mirouse V, Swick LL, Kazgan N, St Johnston D, Brenman JE. LKB1 and AMPK maintain epithelial cell polarity under energetic stress. J Cell Biol 2007, 177(3):387-392. 10.1083/jcb.200702053, 2064817, 17470638.
    • (2007) J Cell Biol , vol.177 , Issue.3 , pp. 387-392
    • Mirouse, V.1    Swick, L.L.2    Kazgan, N.3    St Johnston, D.4    Brenman, J.E.5
  • 7
    • 67049100271 scopus 로고    scopus 로고
    • LKB1 regulates polarity remodeling and adherens junction formation in the Drosophila eye
    • 10.1073/pnas.0812469106, 2690039, 19443685
    • Amin N, Khan A, St Johnston D, Tomlinson I, Martin S, Brenman J, McNeill H. LKB1 regulates polarity remodeling and adherens junction formation in the Drosophila eye. Proc Natl Acad Sci USA 2009, 106(22):8941-8946. 10.1073/pnas.0812469106, 2690039, 19443685.
    • (2009) Proc Natl Acad Sci USA , vol.106 , Issue.22 , pp. 8941-8946
    • Amin, N.1    Khan, A.2    St Johnston, D.3    Tomlinson, I.4    Martin, S.5    Brenman, J.6    McNeill, H.7
  • 8
    • 0037461735 scopus 로고    scopus 로고
    • A role for Drosophila LKB1 in anterior-posterior axis formation and epithelial polarity
    • 10.1038/nature01296, 12540903
    • Martin SG, St Johnston D. A role for Drosophila LKB1 in anterior-posterior axis formation and epithelial polarity. Nature 2003, 421(6921):379-384. 10.1038/nature01296, 12540903.
    • (2003) Nature , vol.421 , Issue.6921 , pp. 379-384
    • Martin, S.G.1    St Johnston, D.2
  • 9
    • 0034090975 scopus 로고    scopus 로고
    • The C. elegans par-4 gene encodes a putative serine-threonine kinase required for establishing embryonic asymmetry
    • Watts JL, Morton DG, Bestman J, Kemphues KJ. The C. elegans par-4 gene encodes a putative serine-threonine kinase required for establishing embryonic asymmetry. Development 2000, 127(7):1467-1475.
    • (2000) Development , vol.127 , Issue.7 , pp. 1467-1475
    • Watts, J.L.1    Morton, D.G.2    Bestman, J.3    Kemphues, K.J.4
  • 10
    • 1542777034 scopus 로고    scopus 로고
    • Complete polarization of single intestinal epithelial cells upon activation of LKB1 by STRAD
    • 10.1016/S0092-8674(04)00114-X, 15016379
    • Baas AF, Kuipers J, van der Wel NN, Batlle E, Koerten HK, Peters PJ, Clevers HC. Complete polarization of single intestinal epithelial cells upon activation of LKB1 by STRAD. Cell 2004, 116(3):457-466. 10.1016/S0092-8674(04)00114-X, 15016379.
    • (2004) Cell , vol.116 , Issue.3 , pp. 457-466
    • Baas, A.F.1    Kuipers, J.2    van der Wel, N.N.3    Batlle, E.4    Koerten, H.K.5    Peters, P.J.6    Clevers, H.C.7
  • 12
    • 44449178868 scopus 로고    scopus 로고
    • Rho GTPases in cancer cell biology
    • 10.1016/j.febslet.2008.04.039, 18460342
    • Vega FM, Ridley AJ. Rho GTPases in cancer cell biology. FEBS Lett 2008, 582(14):2093-2101. 10.1016/j.febslet.2008.04.039, 18460342.
    • (2008) FEBS Lett , vol.582 , Issue.14 , pp. 2093-2101
    • Vega, F.M.1    Ridley, A.J.2
  • 13
    • 63849237020 scopus 로고    scopus 로고
    • Regulation of epithelial apical junctional complex by Rho family GTPases
    • 10.2741/3298, 19273120
    • Samarin S, Nusrat A. Regulation of epithelial apical junctional complex by Rho family GTPases. Front Biosci 2009, 14:1129-1142. 10.2741/3298, 19273120.
    • (2009) Front Biosci , vol.14 , pp. 1129-1142
    • Samarin, S.1    Nusrat, A.2
  • 14
    • 38849204971 scopus 로고    scopus 로고
    • The tumor suppressor LKB1 regulates lung cancer cell polarity by mediating cdc42 recruitment and activity
    • 10.1158/0008-5472.CAN-07-2989, 18245474
    • Zhang S, Schafer-Hales K, Khuri FR, Zhou W, Vertino PM, Marcus AI. The tumor suppressor LKB1 regulates lung cancer cell polarity by mediating cdc42 recruitment and activity. Cancer Res 2008, 68(3):740-748. 10.1158/0008-5472.CAN-07-2989, 18245474.
    • (2008) Cancer Res , vol.68 , Issue.3 , pp. 740-748
    • Zhang, S.1    Schafer-Hales, K.2    Khuri, F.R.3    Zhou, W.4    Vertino, P.M.5    Marcus, A.I.6
  • 15
    • 0033775869 scopus 로고    scopus 로고
    • The TSC1 tumour suppressor hamartin regulates cell adhesion through ERM proteins and the GTPase Rho
    • 10.1038/35010550, 10806479
    • Lamb RF, Roy C, Diefenbach TJ, Vinters HV, Johnson MW, Jay DG, Hall A. The TSC1 tumour suppressor hamartin regulates cell adhesion through ERM proteins and the GTPase Rho. Nat Cell Biol 2000, 2(5):281-287. 10.1038/35010550, 10806479.
    • (2000) Nat Cell Biol , vol.2 , Issue.5 , pp. 281-287
    • Lamb, R.F.1    Roy, C.2    Diefenbach, T.J.3    Vinters, H.V.4    Johnson, M.W.5    Jay, D.G.6    Hall, A.7
  • 16
    • 36248969983 scopus 로고    scopus 로고
    • Actin stress fibres
    • 10.1242/jcs.018473, 17928305
    • Pellegrin S, Mellor H. Actin stress fibres. J Cell Sci 2007, 120(Pt 20):3491-3499. 10.1242/jcs.018473, 17928305.
    • (2007) J Cell Sci , vol.120 , Issue.PART 20 , pp. 3491-3499
    • Pellegrin, S.1    Mellor, H.2
  • 17
    • 13444252631 scopus 로고    scopus 로고
    • GEF means go: turning on RHO GTPases with guanine nucleotide-exchange factors
    • 10.1038/nrm1587, 15688002
    • Rossman KL, Der CJ, Sondek J. GEF means go: turning on RHO GTPases with guanine nucleotide-exchange factors. Nat Rev Mol Cell Biol 2005, 6(2):167-180. 10.1038/nrm1587, 15688002.
    • (2005) Nat Rev Mol Cell Biol , vol.6 , Issue.2 , pp. 167-180
    • Rossman, K.L.1    Der, C.J.2    Sondek, J.3
  • 18
    • 0035138272 scopus 로고    scopus 로고
    • Autoinhibition mechanism of proto-Dbl
    • 10.1128/MCB.21.5.1463-1474.2001, 86692, 11238883
    • Bi F, Debreceni B, Zhu K, Salani B, Eva A, Zheng Y. Autoinhibition mechanism of proto-Dbl. Mol Cell Biol 2001, 21(5):1463-1474. 10.1128/MCB.21.5.1463-1474.2001, 86692, 11238883.
    • (2001) Mol Cell Biol , vol.21 , Issue.5 , pp. 1463-1474
    • Bi, F.1    Debreceni, B.2    Zhu, K.3    Salani, B.4    Eva, A.5    Zheng, Y.6
  • 20
    • 7244247060 scopus 로고    scopus 로고
    • Roles of p-ERM and Rho-ROCK signaling in lymphocyte polarity and uropod formation
    • 10.1083/jcb.200403091, 2172551, 15504914
    • Lee JH, Katakai T, Hara T, Gonda H, Sugai M, Shimizu A. Roles of p-ERM and Rho-ROCK signaling in lymphocyte polarity and uropod formation. J Cell Biol 2004, 167(2):327-337. 10.1083/jcb.200403091, 2172551, 15504914.
    • (2004) J Cell Biol , vol.167 , Issue.2 , pp. 327-337
    • Lee, J.H.1    Katakai, T.2    Hara, T.3    Gonda, H.4    Sugai, M.5    Shimizu, A.6
  • 21
    • 33846297039 scopus 로고    scopus 로고
    • Understanding ERM proteins--the awesome power of genetics finally brought to bear
    • 10.1016/j.ceb.2006.12.004, 17175152
    • Hughes SC, Fehon RG. Understanding ERM proteins--the awesome power of genetics finally brought to bear. Curr Opin Cell Biol 2007, 19(1):51-56. 10.1016/j.ceb.2006.12.004, 17175152.
    • (2007) Curr Opin Cell Biol , vol.19 , Issue.1 , pp. 51-56
    • Hughes, S.C.1    Fehon, R.G.2
  • 22
    • 34547760739 scopus 로고    scopus 로고
    • Activated ezrin promotes cell migration through recruitment of the GEF Dbl to lipid rafts and preferential downstream activation of Cdc42
    • 10.1091/mbc.E06-11-1031, 1949366, 17538024
    • Prag S, Parsons M, Keppler MD, Ameer-Beg SM, Barber P, Hunt J, Beavil AJ, Calvert R, Arpin M, Vojnovic B, et al. Activated ezrin promotes cell migration through recruitment of the GEF Dbl to lipid rafts and preferential downstream activation of Cdc42. Mol Biol Cell 2007, 18(8):2935-2948. 10.1091/mbc.E06-11-1031, 1949366, 17538024.
    • (2007) Mol Biol Cell , vol.18 , Issue.8 , pp. 2935-2948
    • Prag, S.1    Parsons, M.2    Keppler, M.D.3    Ameer-Beg, S.M.4    Barber, P.5    Hunt, J.6    Beavil, A.J.7    Calvert, R.8    Arpin, M.9    Vojnovic, B.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.