Monitoring conformational changes in peroxisome proliferator-activated receptor α by a genetically encoded photoamino acid, cross-linking, and mass spectrometry

Journal of Medicinal Chemistry

Volumn 56, Issue 11, 2013, Pages 4252-4263

  Schwarz, Rico ^a   Tänzler, Dirk ^a   Ihling, Christian H ^a   Müller, Mathias Q ^a   Kölbel, Knut ^a   Sinz, Andrea ^a  

^a MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID DERIVATIVE; AMINO ACID TRANSFER RNA LIGASE; P BENZOYLPHENYLALANINE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PHOTOAMINO ACID; TRANSFER RNA; UNCLASSIFIED DRUG;

ANION EXCHANGE CHROMATOGRAPHY; ARTICLE; BACTERIAL CELL; CHEMICAL REACTION; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYSTAL STRUCTURE; DIMERIZATION; ESCHERICHIA COLI; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIGAND BINDING; MASS SPECTROMETRY; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MONITORING; NONHUMAN; PROTEIN CROSS LINKING; TANDEM MASS SPECTROMETRY;

BENZOPHENONES; BINDING SITES; BUTYRATES; CROSS-LINKING REAGENTS; GENETIC VARIATION; LIGANDS; MODELS, MOLECULAR; OXAZOLES; PHENYLALANINE; PHENYLUREA COMPOUNDS; PPAR ALPHA; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN MULTIMERIZATION; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; TYROSINE; ULTRAVIOLET RAYS;

EID: 84879046065     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm400446b     Document Type: Article

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