An innovative method to study target protein-drug interactions by mass spectrometry

Journal of Medicinal Chemistry

Volumn 52, Issue 9, 2009, Pages 2875-2879

  Müller, Mathias Q ^a   De Koning, Leo J ^b   Schmidt, Andreas ^c   Ihling, Christian ^a   Syha, Yvonne ^d   Rau, Oliver ^d   Mechtler, Karl ^c   Schubert Zsilavecz, Manfred ^d   Sinz, Andrea ^a  

^a MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

^b UNIVERSITY OF AMSTERDAM   (Netherlands)

^c INSTITUTE OF MOLECULAR BIOTECHNOLOGY   (Austria)

^d GOETHE UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BIS(SULFOSUCCINIMIDYL)GLUTARATE; BIS(SULFOSUCCINIMIDYL)SUBERATE; GW 6471; LYSINE; N HYDROXYSUCCINIMIDE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA AGONIST; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ANTAGONIST; REAGENT; UNCLASSIFIED DRUG; YS 81;

ARTICLE; CONFORMATIONAL TRANSITION; CROSS LINKING; CRYSTAL STRUCTURE; DRUG PROTEIN BINDING; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIGAND BINDING; MASS SPECTROMETRY; PROTEIN STRUCTURE; STRUCTURE ANALYSIS; TIME OF FLIGHT MASS SPECTROMETRY;

AMINO ACID SEQUENCE; CRYSTALLOGRAPHY, X-RAY; DRUG DISCOVERY; HYDROLYSIS; LIGANDS; MASS SPECTROMETRY; MODELS, MOLECULAR; OXAZOLES; PHARMACEUTICAL PREPARATIONS; PPAR ALPHA; PROTEIN BINDING; PROTEIN CONFORMATION; REPRODUCIBILITY OF RESULTS; TYROSINE;

EID: 65649108952     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm9000665     Document Type: Article

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