Structural determinants of ligand binding selectivity between the peroxisome proliferator-activated receptors

Proceedings of the National Academy of Sciences of the United States of America

Volumn 98, Issue 24, 2001, Pages 13919-13924

  Xu, H E ^a   Lambert, M H ^a   Montana, V G ^a   Plunket, K D ^a   Moore, L B ^a   Collins, J L ^a   Oplinger, J A ^a   Kliewer, S A ^a   Gampe R T , Jr ^a   McKee, D D ^a   Moore, J T ^a   Willson, T M ^a  

^a GLAXOSMITHKLINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2,4 THIAZOLIDINEDIONE DERIVATIVE; ANTIDIABETIC AGENT; FARGLITAZAR; GW 409544; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; PIOGLITAZONE; RECEPTOR SUBTYPE; ROSIGLITAZONE; THIAZOLIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG SELECTIVITY; DRUG STRUCTURE; LIGAND BINDING; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR UPREGULATION; TRANSCRIPTION REGULATION; X RAY ANALYSIS;

AMINO ACID SEQUENCE; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; HUMANS; LIGANDS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; OXAZOLES; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, CYTOPLASMIC AND NUCLEAR; TRANSCRIPTION FACTORS; TYROSINE;

EID: 0035923672     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.241410198     Document Type: Article

References (33)