Methionine acts as a "magnet" in photoaffinity crosslinking experiments

FEBS Letters

Volumn 580, Issue 7, 2006, Pages 1872-1876

  Wittelsberger, Angela ^a   Thomas, Beena E ^a   Mierke, Dale F ^b   Rosenblatt, Michael ^a  

^a TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b BROWN UNIVERSITY   (United States)

Author keywords

Cyanogen bromide; Methionine scan; Parathyroid hormone receptor 1; Photoaffinity crosslinking; Site directed mutagenesis

Indexed keywords

AMINO ACID; METHIONINE; PARATHYROID HORMONE RECEPTOR;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CROSS LINKING; NONHUMAN; PHOTOAFFINITY LABELING; PRIORITY JOURNAL; PROTEIN DOMAIN;

AMINO ACID SUBSTITUTION; ANIMALS; BENZOPHENONES; CERCOPITHECUS AETHIOPS; COS CELLS; CROSS-LINKING REAGENTS; HUMANS; METHIONINE; PHOTOCHEMISTRY; RECEPTOR, PARATHYROID HORMONE, TYPE 1;

ANIMALIA;

EID: 33644886015     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2006.02.050     Document Type: Article

References (21)

1. A. Bisello, A.E. Adams, D.F. Mierke, M. Pellegrini, M. Rosenblatt, L.J. Suva, and M. Chorev Parathyroid hormone-receptor interactions identified directly by photocross-linking and molecular modeling studies J. Biol. Chem. 273 1998 22498 22505
2. M. Dong, Z. Li, D.I. Pinon, T.P. Lybrand, and L.J. Miller Spatial approximation between the amino terminus of a peptide agonist and the top of the sixth transmembrane segment of the secretin receptor J. Biol. Chem. 279 2004 2894 2903
3. V. Pham, M. Dong, J.D. Wade, L.J. Miller, C.J. Morton, H. Ng, M.W. Parker, and P.M. Sexton Insights into interactions between the alpha-helical region of the salmon calcitonin antagonists and the human calcitonin receptor using photoaffinity labeling J. Biol. Chem. 280 2005 28610 28622
4. Z. Ji, E.M. Hadac, R.M. Henne, S.A. Patel, T.P. Lybrand, and L.J. Miller Direct identification of a distinct site of interaction between the carboxyl-terminal residue of cholecystokinin and the type A cholecystokinin receptor using photoaffinity labeling J. Biol. Chem. 272 1997 24393 24401
5. M. Pellegrini, A.A. Bremer, A.L. Ulfers, N.D. Boyd, and D.F. Mierke Molecular characterization of the substance P-neurokinin-1 receptor complex J. Biol. Chem. 276 2001 22862 22867
6. J. Perodin Residues 293 and 294 are ligand contact points of the human angiotensin type 1 receptor Biochemistry 41 2002 14348 14356
7. G. Dorman, and G.D. Prestwich Benzophenone photophores in biochemistry Biochemistry 33 1994 5661 5673
8. A. Wittelsberger, M. Corich, B.E. Thomas, B.K. Lee, A. Barazza, P. Czodrowski, D.F. Mierke, M. Chorev, and M. Rosenblatt The mid-region of parathyroid hormone (1-34) serves as a functional docking domain in receptor activation Biochemistry 45 2006 2027 2034
9. C. Nakamoto, V. Behar, K.R. Chin, A.E. Adams, L.J. Suva, M. Rosenblatt, and M. Chorev Probing the bimolecular interactions of parathyroid hormone with the human parathyroid hormone/parathyroid hormone-related protein receptor Biochemistry 34 1995 10546 10552
10. C. Lee, T.J. Gardella, A.B. Abou-Samra, S.R. Nussbaum, G.V. Segre, J.T. Potts Jr., H.M. Kronenberg, and H. Juppner Role of the extracellular regions of the parathyroid hormone (PTH)/PTH-related peptide receptor in hormone binding Endocrinology 135 1994 1488 1495
11. R. Kage, S.E. Leeman, J.E. Krause, C.E. Costello, and N.D. Boyd Identification of methionine as the site of covalent attachment of a p-benzoyl-phenylalanine-containing analogue of substance P on the substance P (NK-1) receptor J. Biol. Chem. 271 1996 25797 25800
12. E. Sachon, G. Bolbach, G. Chassaing, S. Lavielle, and S. Sagan Cgamma H2 of Met174 side chain is the site of covalent attachment of a substance P analog photoactivable in position 5 J. Biol. Chem. 277 2002 50409 50414
13. E. Deseke, Y. Nakatani, and G. Ourisson Intrinsic reactivities of amino acids towards photoalkylation with benzophenone - a study preliminary to photolabelling of the transmembrane protein glycophorin A Eur. J. Org. Chem. 1998 243 251
14. A.A. Boucard, B.C. Wilkes, S.A. Laporte, E. Escher, G. Guillemette, and R. Leduc Photolabeling identifies position 172 of the human AT(1) receptor as a ligand contact point: receptor-bound angiotensin II adopts an extended structure Biochemistry 39 2000 9662 9670
15. A.A. Bremer, S.E. Leeman, and N.D. Boyd Evidence for spatial proximity of two distinct receptor regions in the substance P (SP)-neurokinin-1 receptor (NK-1R) complex obtained by photolabeling the NK-1R with p- benzoylphenylalanine3-SP J. Biol. Chem. 276 2001 22857 22861
16. O. Lequin, G. Bolbach, F. Frank, O. Convert, S. Girault-Lagrange, G. Chassaing, S. Lavielle, and S. Sagan Involvement of the second extracellular loop (E2) of the neurokinin-1 receptor in the binding of substance P. Photoaffinity labeling and modeling studies J. Biol. Chem. 277 2002 22386 22394
17. H. Li, D.M. Macdonald, X. Hronowski, C.E. Costello, S.E. Leeman, and N.D. Boyd Further definition of the substance P (SP)/neurokinin-1 receptor complex. MET-174 is the site of photoinsertion p-benzoylphenylalanine4 SP. J. Biol. Chem. 276 2001 10589 10593
18. E. Sachon, G. Bolbach, S. Lavielle, P. Karoyan, and S. Sagan Met174 side chain is the site of photoinsertion of a substance P competitive peptide antagonist photoreactive in position 8 FEBS Lett. 544 2003 45 49
19. D. Macdonald, D.F. Mierke, H. Li, M. Pellegrini, B. Sachais, J.E. Krause, S.E. Leeman, and N.D. Boyd Photoaffinity labeling of mutant neurokinin-1 receptors reveals additional structural features of the substance P/NK-1 receptor complex Biochemistry 40 2001 2530 2539
20. M. Clement, S.S. Martin, M. Beaulieu, C. Chamberland, P. Lavigne, R. Leduc, G. Guillemette, and E. Escher Determining the environment of the ligand binding pocket of the human angiotensin II type I (hAT1) receptor using the methionine proximity assay J. Biol. Chem. 280 2005 27121 27129
21. M. Pellegrini, A. Bisello, M. Rosenblatt, M. Chorev, and D.F. Mierke Binding domain of human parathyroid hormone receptor: from conformation to function Biochemistry 37 1998 12737 12743