Loss of an Igκ gene enhancer in mature B cells results in rapid gene silencing and partial reversible dedifferentiation

Molecular and Cellular Biology

Volumn 33, Issue 10, 2013, Pages 2091-2101

  Zhou, Xiaorong ^a,b   Xiang, Yougui ^a   Ding, Xiaoling ^a   Garrard, William T ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b NANTONG UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN KAPPA CHAIN; IGK; IMMUNOGLOBULIN;

ALLELE; ANIMAL EXPERIMENT; ARTICLE; B LYMPHOCYTE; CELL DEDIFFERENTIATION; CELL MATURATION; CONTROLLED STUDY; EPIGENETICS; GENE DELETION; GENE LOCUS; GENE REARRANGEMENT; GENE SILENCING; MOUSE; NONHUMAN; PRIORITY JOURNAL; ANIMAL; CELL CULTURE; CYTOLOGY; ENHANCER REGION; GENE EXPRESSION; GENETIC ENGINEERING; GENETICS; IMMUNOLOGICAL TOLERANCE; MOLECULAR CLONING; PHYSIOLOGY; SPLEEN; TRANSGENIC MOUSE;

ANIMALS; B-LYMPHOCYTES; CELL DEDIFFERENTIATION; CELLS, CULTURED; CLONING, MOLECULAR; ENHANCER ELEMENTS, GENETIC; GENE EXPRESSION; GENE REARRANGEMENT; GENE SILENCING; GENETIC ENGINEERING; IMMUNE TOLERANCE; IMMUNOGLOBULINS; MICE; MICE, TRANSGENIC; SEQUENCE DELETION; SPLEEN;

MLCS; MLOWN;

EID: 84878977046     PISSN: 02707306     EISSN: 10985549     Source Type: Journal    
DOI: 10.1128/MCB.01569-12     Document Type: Article

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