Cutting edge: Expansion and activation of a population of autoreactive marginal zone B cells in a model of estrogen-induced lupus

Journal of Immunology

Volumn 167, Issue 4, 2001, Pages 1886-1890

  Grimaldi, C M ^a   Michael, D J ^a   Diamond, B ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; ESTRADIOL;

ANIMAL CELL; ANIMAL MODEL; ANTIBODY TITER; ARTICLE; AUTOIMMUNITY; B LYMPHOCYTE; CELL ACTIVATION; CELL MATURATION; CELL POPULATION; CELL SURVIVAL; CELLULAR DISTRIBUTION; CONTROLLED STUDY; LUPUS ERYTHEMATOSUS; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION; T LYMPHOCYTE;

EID: 0035881589     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.167.4.1886     Document Type: Article

References (32)

1. Systemic lupus erythematosus
2. Estrogen up-regulates Bcl-2 and blocks tolerance induction of naive B cells
3. Bromocriptine restores tolerance in estrogen-treated mice
4. Induction of tolerance to an IgG autoantibody
5. Light chain usage in anti-double-stranded DNA B cell subsets: Role in cell fate determination
6. Cutting edge: A role for CD1 in the pathogenesis of lupus in NZB/NZW mice
7. Genetic dissection of B cell traits in New Zealand black mice: The expanded population of B cells expressing up-regulated costimulatory molecules shows linkage to Nba2
8. 1 mice
9. Estrogen increases the number of plasma cells and enhances their autoantibody production in nonautoimmune C57BL/6 mice
10. Positive selection from newly formed to marginal zone B cells depends on the rate of clonal production. CD19, and btk
11. 17 β-estradiol, but not 5 α-dihydrotestosterone, augments antibodies to double-stranded deoxyribonucleic acid in non-autoimmune C57BL/6J mice
12. Estrogen influences the differentiation, proliferation, and survival of early B-lineage precursors
13. The role of estrogen receptors and androgen receptors in sex steroid regulation of B lymphopoiesis
14. Estrogen suppresses stromal cell-dependent lymphopoiesis in culture
15. B cell development in the spleen takes place in discrete steps and is determined by the quality of B cell receptor-derived signals
16. BAFF mediates survival of peripheral immature B lymphocytes
17. 1 mice
18. Sex hormone modulation of autoimmunity in NZB/NZW mice
19. Oestrogen is a potent disease accelerator in SLE-prone MRL tpr/tpr mice
20. B cell receptor-induced apoptosis in primary transitional murine B cells: Signaling requirements and modulation by T cell help
21. Negative selection of immature B cells by receptor editing or deletion is determined by site of antigen encounter
22. IgG anti-DNA autoantibodies within an individual autoimmune mouse are the products of clonal selection
23. Anti-DNA antibodies from autoimmune mice arise by clonal expansion and somatic mutation
24. 1 mice with monoclonal antibody to L3T4
25. CTLA4Ig inhibits T cell-dependent B-cell maturation in murine systemic lupus erythematosus
26. A two-phase model of B-cell activation
27. CD1.1 expression by mouse antigen-presenting cells and marginal zone B cells
28. In vitro stimulation of human tonsillar subepithelial B cells: Requirement for interaction with activated T cells
29. The double edged sword of the immune response: Mutational analysis of a murine anti-pneumococcal, anti-DNA antibody
30. Pathogenic autoantibodies are routinely generated during the response to foreign antigen: A paradigm for autoimmune disease
31. Functional consequences of the developmental arrest and follicular exclusion of anti-double-stranded DNA B cells
32. Antigen-induced exclusion from follicles and anergy are separate and complementory processes that influence peripheral B cell fate