-
1
-
-
0342711256
-
In vivo ablation of surface immunoglobulin on mature B cells by inducible gene targeting results in rapid cell death
-
Lam, K. P., R. Kuhn, and K. Rajewsky. 1997. In vivo ablation of surface immunoglobulin on mature B cells by inducible gene targeting results in rapid cell death. Cell 90: 1073-1083.
-
(1997)
Cell
, vol.90
, pp. 1073-1083
-
-
Lam, K.P.1
Kuhn, R.2
Rajewsky, K.3
-
2
-
-
2942582913
-
Survival of resting mature B lymphocytes depends on BCR signaling via the Igα/β heterodimer
-
Kraus, M., M. B. Alimzhanov, N. Rajewsky, and K. Rajewsky. 2004. Survival of resting mature B lymphocytes depends on BCR signaling via the Igα/β heterodimer. Cell 117: 787-800.
-
(2004)
Cell
, vol.117
, pp. 787-800
-
-
Kraus, M.1
Alimzhanov, M.B.2
Rajewsky, N.3
Rajewsky, K.4
-
3
-
-
0033214186
-
Positive selection of thymocytes: The long and winding road
-
Anderson, G., K. J. Hare, and E. J. Jenkinson. 1999. Positive selection of thymocytes: the long and winding road. Immunol. Today 20: 463-468.
-
(1999)
Immunol. Today
, vol.20
, pp. 463-468
-
-
Anderson, G.1
Hare, K.J.2
Jenkinson, E.J.3
-
4
-
-
0141886227
-
Cutting edge: Signaling and cell surface expression of a μ H chain in the absence of λ5: a paradigm revisited
-
Schuh, W., S. Meister, E. Roth, and H. M. Jack. 2003. Cutting edge: signaling and cell surface expression of a μ H chain in the absence of λ5: a paradigm revisited. J. Immunol. 171: 3343-3347.
-
(2003)
J. Immunol
, vol.171
, pp. 3343-3347
-
-
Schuh, W.1
Meister, S.2
Roth, E.3
Jack, H.M.4
-
5
-
-
2942642372
-
Surface μ heavy chain signals down-regulation of the VDJ-recombinase machinery in the absence of surrogate light chain components
-
Galler, G. R., C. Mundt, M. Parker, R. Pelanda, I. L. Martensson, and T. H. Winkler. 2004. Surface μ heavy chain signals down-regulation of the VDJ-recombinase machinery in the absence of surrogate light chain components. J. Exp. Med. 199: 1523-1532.
-
(2004)
J. Exp. Med
, vol.199
, pp. 1523-1532
-
-
Galler, G.R.1
Mundt, C.2
Parker, M.3
Pelanda, R.4
Martensson, I.L.5
Winkler, T.H.6
-
6
-
-
0037303456
-
Emergence and evolution of functional heavy-chain antibodies in Camelidae
-
Conrath, K. E., U. Wernery, S. Muyldermans, and V. K. Nguyen. 2003. Emergence and evolution of functional heavy-chain antibodies in Camelidae. Dev. Comp. Immunol. 27: 87-103.
-
(2003)
Dev. Comp. Immunol
, vol.27
, pp. 87-103
-
-
Conrath, K.E.1
Wernery, U.2
Muyldermans, S.3
Nguyen, V.K.4
-
7
-
-
24744468996
-
Expression of a dromedary heavy chain-only antibody and B cell development in the mouse
-
Zou, X., J. A. Smith, V. K. Nguyen, L. Ren, K. Luyten, S. Muyldermans, and M. Bruggemann. 2005. Expression of a dromedary heavy chain-only antibody and B cell development in the mouse. J. Immunol. 175: 3769-3779.
-
(2005)
J. Immunol
, vol.175
, pp. 3769-3779
-
-
Zou, X.1
Smith, J.A.2
Nguyen, V.K.3
Ren, L.4
Luyten, K.5
Muyldermans, S.6
Bruggemann, M.7
-
8
-
-
0026076096
-
Allelic exclusion in transgenic mice expressing a heavy chain disease-like human μ protein
-
Corcos, D., A. Iglesias, O. Dunda, D. Bucchini, and J. Jami. 1991. Allelic exclusion in transgenic mice expressing a heavy chain disease-like human μ protein. Eur. J. Immunol. 21: 2711-2716.
-
(1991)
Eur. J. Immunol
, vol.21
, pp. 2711-2716
-
-
Corcos, D.1
Iglesias, A.2
Dunda, O.3
Bucchini, D.4
Jami, J.5
-
9
-
-
0035284866
-
Expression of a V region-less B cell receptor confers a tolerance-like phenotype on transgenic B cells
-
Corcos, D., A. Grandien, A. Vazquez, O. Dunda, P. Lores, and D. Bucchini. 2001. Expression of a V region-less B cell receptor confers a tolerance-like phenotype on transgenic B cells. J. Immunol. 166: 3083-3089.
-
(2001)
J. Immunol
, vol.166
, pp. 3083-3089
-
-
Corcos, D.1
Grandien, A.2
Vazquez, A.3
Dunda, O.4
Lores, P.5
Bucchini, D.6
-
10
-
-
0020632426
-
Molecular basis of a mouse strain-specific anti-hapten response
-
Loh, D. Y., A. L. Bothwell, M. E. White-Scharf, T. Imanishi-Kari, and D. Baltimore. 1983. Molecular basis of a mouse strain-specific anti-hapten response. Cell 33: 85-93.
-
(1983)
Cell
, vol.33
, pp. 85-93
-
-
Loh, D.Y.1
Bothwell, A.L.2
White-Scharf, M.E.3
Imanishi-Kari, T.4
Baltimore, D.5
-
13
-
-
0029937038
-
A quasi-monoclonal mouse
-
Cascalho, M., A. Ma, S. Lee, L. Masat, and M. Wabl. 1996. A quasi-monoclonal mouse. Science 272: 1649-1652.
-
(1996)
Science
, vol.272
, pp. 1649-1652
-
-
Cascalho, M.1
Ma, A.2
Lee, S.3
Masat, L.4
Wabl, M.5
-
14
-
-
0028347698
-
Influence of immunoglobulin heavy- and light-chain expression on B-cell differentiation
-
Young, F., B. Ardman, Y. Shinkai, R. Lansford, T. K. Blackwell, M. Mendelsohn, A. Rolink, F. Melchers, and F. W. Alt. 1994. Influence of immunoglobulin heavy- and light-chain expression on B-cell differentiation. Genes Dev. 8: 1043-1057.
-
(1994)
Genes Dev
, vol.8
, pp. 1043-1057
-
-
Young, F.1
Ardman, B.2
Shinkai, Y.3
Lansford, R.4
Blackwell, T.K.5
Mendelsohn, M.6
Rolink, A.7
Melchers, F.8
Alt, F.W.9
-
15
-
-
0026720075
-
Tight control of gene expression in mammalian cells by tetracycline-responsive promoters
-
Gossen, M., and H. Bujard. 1992. Tight control of gene expression in mammalian cells by tetracycline-responsive promoters. Proc. Natl. Acad. Sci. USA 89: 5547-5551.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 5547-5551
-
-
Gossen, M.1
Bujard, H.2
-
16
-
-
0029586870
-
Conditional gene expression in secretory tissues and skin of transgenic mice using the MMTV-LTR and the tetracycline responsive system
-
Hennighausen, L., R. J. Wall, U. Tillmann, M. Li, and P. A. Furth. 1995. Conditional gene expression in secretory tissues and skin of transgenic mice using the MMTV-LTR and the tetracycline responsive system. J. Cell. Biochem. 59: 463-472.
-
(1995)
J. Cell. Biochem
, vol.59
, pp. 463-472
-
-
Hennighausen, L.1
Wall, R.J.2
Tillmann, U.3
Li, M.4
Furth, P.A.5
-
17
-
-
0032966673
-
Conditional expression and signaling of a specifically designed Gi-coupled receptor in transgenic mice
-
Redfern, C. H., P. Coward, M. Y. Degtyarev, E. K. Lee, A. T. Kwa, L. Hennighausen, H. Bujard, G. I. Fishman, and B. R. Conklin. 1999. Conditional expression and signaling of a specifically designed Gi-coupled receptor in transgenic mice. Nat. Biotechnol. 17: 165-169.
-
(1999)
Nat. Biotechnol
, vol.17
, pp. 165-169
-
-
Redfern, C.H.1
Coward, P.2
Degtyarev, M.Y.3
Lee, E.K.4
Kwa, A.T.5
Hennighausen, L.6
Bujard, H.7
Fishman, G.I.8
Conklin, B.R.9
-
18
-
-
0018726056
-
A new mouse myeloma cell line that has lost immunoglobulin expression but permits the construction of antibody-secreting hybrid cell lines
-
Kearney, J. F., A. Radbruch, B. Liesegang, and K. Rajewsky. 1979. A new mouse myeloma cell line that has lost immunoglobulin expression but permits the construction of antibody-secreting hybrid cell lines. J. Immunol. 123: 1548-1550.
-
(1979)
J. Immunol
, vol.123
, pp. 1548-1550
-
-
Kearney, J.F.1
Radbruch, A.2
Liesegang, B.3
Rajewsky, K.4
-
19
-
-
0024114728
-
A novel 34-kd protein co-isolated with the IgM molecule in surface IgM-expressing cells
-
Hombach, J., L. Leclercq, A. Radbruch, K. Rajewsky, and M. Reth. 1988. A novel 34-kd protein co-isolated with the IgM molecule in surface IgM-expressing cells. EMBO J. 7: 3451-3456.
-
(1988)
EMBO J
, vol.7
, pp. 3451-3456
-
-
Hombach, J.1
Leclercq, L.2
Radbruch, A.3
Rajewsky, K.4
Reth, M.5
-
20
-
-
0028784187
-
Surrogate light chain-dependent selection of Ig heavy chain V regions
-
Keyna, U., G. B. Beck-Engeser, J. Jongstra, S. E. Applequist, and H. M. Jack. 1995. Surrogate light chain-dependent selection of Ig heavy chain V regions. J. Immunol. 155: 5536-5542.
-
(1995)
J. Immunol
, vol.155
, pp. 5536-5542
-
-
Keyna, U.1
Beck-Engeser, G.B.2
Jongstra, J.3
Applequist, S.E.4
Jack, H.M.5
-
21
-
-
0027096270
-
A different sort of Mott cell
-
Jack, H. M., G. Beck-Engeser, B. Sloan, M. L. Wong, and M. Wabl. 1992. A different sort of Mott cell. Proc. Natl. Acad. Sci. USA 89: 11688-11691.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 11688-11691
-
-
Jack, H.M.1
Beck-Engeser, G.2
Sloan, B.3
Wong, M.L.4
Wabl, M.5
-
22
-
-
0042834298
-
Immunoglobulin μ heavy chains do not mediate tyrosine phosphorylation of Igα from the ER-cis-Golgi
-
Mielenz, D., A. Ruschel, C. Vettermann, and H. M. Jack. 2003. Immunoglobulin μ heavy chains do not mediate tyrosine phosphorylation of Igα from the ER-cis-Golgi. J. Immunol. 171: 3091-3101.
-
(2003)
J. Immunol
, vol.171
, pp. 3091-3101
-
-
Mielenz, D.1
Ruschel, A.2
Vettermann, C.3
Jack, H.M.4
-
23
-
-
1842424798
-
B cell-dependent TCR diversification
-
João, C. M., B. M. Ogle, C. Gay-Rabinstein, J. L. Platt, and M. Cascalho. 2004. B cell-dependent TCR diversification. J. Immunol. 172: 4709-4716.
-
(2004)
J. Immunol
, vol.172
, pp. 4709-4716
-
-
João, C.M.1
Ogle, B.M.2
Gay-Rabinstein, C.3
Platt, J.L.4
Cascalho, M.5
-
24
-
-
0014949207
-
Cleavage of structural proteins during the assembly of the head of bacteriophage T4
-
Laemmli, U. K. 1970. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227: 680-685.
-
(1970)
Nature
, vol.227
, pp. 680-685
-
-
Laemmli, U.K.1
-
25
-
-
0027465094
-
The surrogate light chain in B-cell development
-
Melchers, F., H. Karasuyama, D. Haasner, S. Bauer, A. Kudo, N. Sakaguchi, B. Jameson, and A. Rolink. 1993. The surrogate light chain in B-cell development. Immunol. Today 14: 60-68.
-
(1993)
Immunol. Today
, vol.14
, pp. 60-68
-
-
Melchers, F.1
Karasuyama, H.2
Haasner, D.3
Bauer, S.4
Kudo, A.5
Sakaguchi, N.6
Jameson, B.7
Rolink, A.8
-
26
-
-
0027515312
-
Early B cell development requires μ signaling
-
Iglesias, A., A. Nichogiannopoulou, G. S. Williams, H. Flaswinkel, and G. Kohler. 1993. Early B cell development requires μ signaling. Eur. J. Immunol. 23: 2622-2630.
-
(1993)
Eur. J. Immunol
, vol.23
, pp. 2622-2630
-
-
Iglesias, A.1
Nichogiannopoulou, A.2
Williams, G.S.3
Flaswinkel, H.4
Kohler, G.5
-
27
-
-
0030006070
-
Clonal selection and learning in the antibody system
-
Rajewsky, K. 1996. Clonal selection and learning in the antibody system. Nature 381: 751-758.
-
(1996)
Nature
, vol.381
, pp. 751-758
-
-
Rajewsky, K.1
-
28
-
-
33644978463
-
Gene repression by pax5 in B cells is essential for blood cell homeostasis and is reversed in plasma cells
-
Delogu, A., A. Schebesta, Q. Sun, K. Aschenbrenner, T. Perlot, and M. Busslinger. 2006. Gene repression by pax5 in B cells is essential for blood cell homeostasis and is reversed in plasma cells. Immunity 24: 269-281.
-
(2006)
Immunity
, vol.24
, pp. 269-281
-
-
Delogu, A.1
Schebesta, A.2
Sun, Q.3
Aschenbrenner, K.4
Perlot, T.5
Busslinger, M.6
-
29
-
-
0035186661
-
B cell development is arrested at the immature B cell stage in mice carrying a mutation in the cytoplasmic domain of immunoglobulin β
-
Reichlin, A., Y. Hu, E. Meffre, H. Nagaoka, S. Gong, M. Kraus, K. Rajewsky, and M. C. Nussenzweig. 2001. B cell development is arrested at the immature B cell stage in mice carrying a mutation in the cytoplasmic domain of immunoglobulin β. J. Exp. Med. 193: 13-23.
-
(2001)
J. Exp. Med
, vol.193
, pp. 13-23
-
-
Reichlin, A.1
Hu, Y.2
Meffre, E.3
Nagaoka, H.4
Gong, S.5
Kraus, M.6
Rajewsky, K.7
Nussenzweig, M.C.8
-
30
-
-
0000082704
-
Preparation of immunogens
-
C. A. Williams, and M. W. Case, eds. Academic, New York, pp
-
Chase, M. W. 1967. Preparation of immunogens. In Methods in Immunology and Immunochemistry. C. A. Williams, and M. W. Case, eds. Academic, New York, pp. 197-209.
-
(1967)
Methods in Immunology and Immunochemistry
, pp. 197-209
-
-
Chase, M.W.1
-
32
-
-
0034896499
-
Unassembled Ig heavy chains do not cycle from BiP in vivo but require light chains to trigger their release
-
Vanhove, M., Y. K. Usherwood, and L. M. Hendershot. 2001. Unassembled Ig heavy chains do not cycle from BiP in vivo but require light chains to trigger their release. Immunity 15: 105-114.
-
(2001)
Immunity
, vol.15
, pp. 105-114
-
-
Vanhove, M.1
Usherwood, Y.K.2
Hendershot, L.M.3
-
33
-
-
33645156429
-
From acute ER stress to physiological roles of the unfolded protein response
-
Wu, J., and R. J. Kaufman. 2006. From acute ER stress to physiological roles of the unfolded protein response. Cell Death Differ. 13: 374-384.
-
(2006)
Cell Death Differ
, vol.13
, pp. 374-384
-
-
Wu, J.1
Kaufman, R.J.2
-
34
-
-
0036604966
-
Regulation of B cell fates by BCR signaling components
-
Kurosaki, T. 2002. Regulation of B cell fates by BCR signaling components. Curr. Opin. Immunol. 14: 341-347.
-
(2002)
Curr. Opin. Immunol
, vol.14
, pp. 341-347
-
-
Kurosaki, T.1
-
35
-
-
1542377328
-
B cell receptor signal strength determines B cell fate
-
Casola, S., K. L. Otipoby, M. Alimzhanov, S. Humme, N. Uyttersprot, J. L. Kutok, M. C. Carroll, and K. Rajewsky. 2004. B cell receptor signal strength determines B cell fate. Nat. Immunol. 5: 317-327.
-
(2004)
Nat. Immunol
, vol.5
, pp. 317-327
-
-
Casola, S.1
Otipoby, K.L.2
Alimzhanov, M.3
Humme, S.4
Uyttersprot, N.5
Kutok, J.L.6
Carroll, M.C.7
Rajewsky, K.8
-
36
-
-
0033103453
-
Unique single-domain antigen binding fragments derived from naturally occurring camel heavy-chain antibodies
-
Muyldermans, S., and M. Lauwereys. 1999. Unique single-domain antigen binding fragments derived from naturally occurring camel heavy-chain antibodies. J. Mol. Recognit. 12: 131-140.
-
(1999)
J. Mol. Recognit
, vol.12
, pp. 131-140
-
-
Muyldermans, S.1
Lauwereys, M.2
-
37
-
-
0028962371
-
A new antigen receptor gene family that undergoes rearrangement and extensive somatic diversification in sharks
-
Greenberg, A. S., D. Avila, M. Hughes, A. Hughes, E. C. McKinny, and M. F. Flajnik. 1995. A new antigen receptor gene family that undergoes rearrangement and extensive somatic diversification in sharks. Nature 374: 168-173.
-
(1995)
Nature
, vol.374
, pp. 168-173
-
-
Greenberg, A.S.1
Avila, D.2
Hughes, M.3
Hughes, A.4
McKinny, E.C.5
Flajnik, M.F.6
-
38
-
-
0031984559
-
Distinct patterns of IgH structure and organization in a divergent lineage of chrondrichthyan fishes
-
Rast, J. P., C. T. Amemiya, R. T. Litman, S. J. Strong, and G. W. Litman. 1998. Distinct patterns of IgH structure and organization in a divergent lineage of chrondrichthyan fishes. Immunogenetics 47: 234-245.
-
(1998)
Immunogenetics
, vol.47
, pp. 234-245
-
-
Rast, J.P.1
Amemiya, C.T.2
Litman, R.T.3
Strong, S.J.4
Litman, G.W.5
-
39
-
-
33750091312
-
Generation of heavy-chain-only antibodies in mice
-
Janssens, R., S. Dekker, R. W. Hendriks, G. Panayotou, A. van Remoortere, J. K. San, F. Grosveld, and D. Drabek. 2006. Generation of heavy-chain-only antibodies in mice. Proc. Natl. Acad. Sci. USA 103: 15130-15135.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 15130-15135
-
-
Janssens, R.1
Dekker, S.2
Hendriks, R.W.3
Panayotou, G.4
van Remoortere, A.5
San, J.K.6
Grosveld, F.7
Drabek, D.8
-
40
-
-
0028884537
-
BiP binding sequences in antibodies
-
Knarr, G., M. J. Gething, S. Modrow, and J. Buchner. 1995. BiP binding sequences in antibodies. J. Biol. Chem. 270: 27589-27594.
-
(1995)
J. Biol. Chem
, vol.270
, pp. 27589-27594
-
-
Knarr, G.1
Gething, M.J.2
Modrow, S.3
Buchner, J.4
-
41
-
-
0021659633
-
Loss of a consensus splice signal in a mutant immunoglobulin gene eliminates the CH1 domain exon from the mRNA
-
Brandt, C. R., S. L. Morrison, B. K. Birshtein, and C. Milcarek. 1984. Loss of a consensus splice signal in a mutant immunoglobulin gene eliminates the CH1 domain exon from the mRNA. Mol. Cell. Biol. 4: 1270-1277.
-
(1984)
Mol. Cell. Biol
, vol.4
, pp. 1270-1277
-
-
Brandt, C.R.1
Morrison, S.L.2
Birshtein, B.K.3
Milcarek, C.4
-
42
-
-
0029379728
-
Pre-B-cell development in the absence of λ5 in transgenic mice expressing a heavy-chain disease protein
-
Corcos, D., O. Dunda, C. Butor, J. Y. Cesbron, P. Lores, D. Bucchini, and J. Jami. 1995. Pre-B-cell development in the absence of λ5 in transgenic mice expressing a heavy-chain disease protein. Curr. Biol. 5: 1140-1148.
-
(1995)
Curr. Biol
, vol.5
, pp. 1140-1148
-
-
Corcos, D.1
Dunda, O.2
Butor, C.3
Cesbron, J.Y.4
Lores, P.5
Bucchini, D.6
Jami, J.7
-
44
-
-
0031692641
-
The role of the B cell receptor V region in peripheral B cell survival
-
Rosado, M. M., and A. A. Freitas. 1998. The role of the B cell receptor V region in peripheral B cell survival. Eur. J. Immunol. 28: 2685-2693.
-
(1998)
Eur. J. Immunol
, vol.28
, pp. 2685-2693
-
-
Rosado, M.M.1
Freitas, A.A.2
-
45
-
-
0023461183
-
Molecular basis of the cell-surface expression of immunoglobulin μ chain without light chain in human B lymphocytes
-
Pollok, B. A., R. Anker, P. Eldridge, L. Hendershot, and D. Levitt. 1987. Molecular basis of the cell-surface expression of immunoglobulin μ chain without light chain in human B lymphocytes. Proc. Natl. Acad. Sci. USA 84: 9199-9203.
-
(1987)
Proc. Natl. Acad. Sci. USA
, vol.84
, pp. 9199-9203
-
-
Pollok, B.A.1
Anker, R.2
Eldridge, P.3
Hendershot, L.4
Levitt, D.5
-
46
-
-
0942279504
-
B-cell homeostasis, competition, resources, and positive selection by self-antigens
-
Rev
-
Gaudin, E., M. Rosado, F. Agenes, A. McLean, and A. A. Freitas. 2004. B-cell homeostasis, competition, resources, and positive selection by self-antigens. Immunol. Rev. 197: 102-115.
-
(2004)
Immunol
, vol.197
, pp. 102-115
-
-
Gaudin, E.1
Rosado, M.2
Agenes, F.3
McLean, A.4
Freitas, A.A.5
-
47
-
-
28844497905
-
Rapid B cell receptor-induced unfolded protein response in nonsecretory B cells correlates with pro- versus antiapoptotic cell fate
-
Skalet, A. H., J. A. Isler, L. B. King, H. P. Harding, D. Ron, and J. G. Monroe. 2005. Rapid B cell receptor-induced unfolded protein response in nonsecretory B cells correlates with pro- versus antiapoptotic cell fate. J. Biol. Chem. 280: 39762-39771.
-
(2005)
J. Biol. Chem
, vol.280
, pp. 39762-39771
-
-
Skalet, A.H.1
Isler, J.A.2
King, L.B.3
Harding, H.P.4
Ron, D.5
Monroe, J.G.6
-
48
-
-
0037073712
-
Activation of an unfolded protein response during differentiation of antibody-secreting B cells
-
Gass, J. N., N. M. Gifford, and J. W. Brewer. 2002. Activation of an unfolded protein response during differentiation of antibody-secreting B cells. J. Biol. Chem. 277: 49047-49054.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 49047-49054
-
-
Gass, J.N.1
Gifford, N.M.2
Brewer, J.W.3
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