Interactions between cytochromes P450 2B4 (CYP2B4) and 1A2 (CYP1A2) lead to alterations in toluene disposition and P450 uncoupling

Biochemistry

Volumn 52, Issue 23, 2013, Pages 4003-4013

  Reed, James R ^a   Cawley, George F ^a   Backes, Wayne L ^a  

^a LOUISIANA STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEX FORMATIONS; CONFORMATIONAL CHANGE; CYTOCHROMES P450; HYDROGEN RADICAL; NADPH OXIDATION; PRODUCT FORMATION; PRODUCTION OF HYDROGEN; RATE-LIMITING STEPS;

METABOLISM; REACTION KINETICS; TOLUENE;

PHYSIOLOGY;

BENZYL ALCOHOL; CRESOL; CYTOCHROME P450 1A2; CYTOCHROME P450 2B4; TOLUENE;

ARTICLE; BINDING AFFINITY; CATALYSIS; COMPLEX FORMATION; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; ENZYME SUBSTRATE; INHIBITION KINETICS; PEROXIDATION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN METABOLISM; PROTEIN PROTEIN INTERACTION;

ANIMALS; ARYL HYDROCARBON HYDROXYLASES; CYTOCHROME P-450 CYP1A2; HYDROGEN PEROXIDE; KINETICS; NADPH-FERRIHEMOPROTEIN REDUCTASE; OXIDATION-REDUCTION; PHOSPHATIDYLCHOLINES; PROTEIN BINDING; RABBITS; SOLUTIONS; SOLVENTS; TOLUENE;

EID: 84878931723     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi400422a     Document Type: Article

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