Inhibition of cytochrome P450 1A2-mediated metabolism and production of reactive oxygen species by heme oxygenase-1 in rat liver microsomes

Drug Metabolism Letters

Volumn 5, Issue 1, 2011, Pages 6-16

  Reed, James R ^a   Cawley, George F ^a   Backes, Wayne L ^a  

^a LOUISIANA STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Cytochrome P450; Heme oxygenase 1; Metabolism; Reactive oxygen species

Indexed keywords

BETA NAPHTHOFLAVONE; CADMIUM CHLORIDE; CYTOCHROME P450 1A2; ETHOXYRESORUFIN; HEME; HEME OXYGENASE 1; HYDROGEN PEROXIDE; HYDROXYL RADICAL; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE FERRIHEMOPROTEIN REDUCTASE; SUPEROXIDE DISMUTASE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BINDING COMPETITION; BIOLOGICAL ACTIVITY; CELL ISOLATION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INDUCTION; ENZYME METABOLISM; ENZYME SUBSTRATE; LIVER MICROSOME; LIVER PROTECTION; MALE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN FUNCTION; RAT;

ANIMALS; BETA-NAPHTHOFLAVONE; CADMIUM CHLORIDE; CYTOCHROMES; ENZYME INDUCTION; HEME; HEME OXYGENASE (DECYCLIZING); HYDROGEN PEROXIDE; HYDROXYL RADICAL; KINETICS; LIVER; MALE; MICROSOMES, LIVER; NADPH-FERRIHEMOPROTEIN REDUCTASE; OXAZINES; OXIDATION-REDUCTION; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; SUBSTRATE SPECIFICITY;

RATTUS;

EID: 79551633925     PISSN: 18723128     EISSN: None     Source Type: Journal    
DOI: 10.2174/187231211794455253     Document Type: Article

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