Kinetics of dithionite-dependent reduction of cytochrome P450 3A4: Heterogeneity of the enzyme caused by its oligomerization

Biochemistry

Volumn 44, Issue 42, 2005, Pages 13902-13913

  Davydov, Dmitri R ^a   Fernando, Harshica ^a   Baas, Bradley J ^b   Sligar, Stephen G ^b   Halpert, James R ^a  

^a University of Texas Medical Branch School of Medicine   (United States)

^b UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MEMBRANES; MONOMERS; PROTEINS; SUBSTRATES;

DITHIONITE; HEME PROTEINS; PROTEOLIPOSOMES;

ENZYMES;

BROMOCRIPTINE; CYTOCHROME P450 3A4; DITHIONITE; LIPID; LIPOSOME; PROTEIN; SULFUR OXIDE;

AMPLITUDE MODULATION; ARTICLE; BINDING KINETICS; CONFORMATIONAL TRANSITION; ENZYME KINETICS; EQUILIBRIUM CONSTANT; GENETIC HETEROGENEITY; MATHEMATICAL ANALYSIS; MEMBRANE BINDING; NONHUMAN; OLIGOMERIZATION; PHASE TRANSITION; PRIORITY JOURNAL; REDUCTION KINETICS;

BIOPOLYMERS; CYTOCHROME P-450 CYP3A; DITHIONITE; KINETICS; MICROSOMES, LIVER; OXIDATION-REDUCTION; PROTEOLIPIDS;

EID: 27144459868     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi0509346     Document Type: Article

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