Heteromeric complex formation between CYP2E1 and CYP1A2: Evidence for the involvement of electrostatic interactions

Biochemistry

Volumn 45, Issue 51, 2006, Pages 15807-15816

  Kelley, Rusty W ^a   Cheng, Dongmei ^a   Backes, Wayne L ^a  

^a LOUISIANA STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALKYLATION; BINDING ENERGY; COMPUTER SIMULATION; ELECTROSTATICS; ENZYME KINETICS; IONIC STRENGTH;

HETEROMERIC CYP2E1-CYP1A2 COMPLEXES; RECONSTITUTED SYSTEMS; REDUCTASE CONCENTRATIONS;

PROTEINS;

4 (2 HYDROXYETHYL) 1 PIPERAZINEETHANESULFONIC ACID; CYTOCHROME P450 1A2; CYTOCHROME P450 2B4; CYTOCHROME P450 2E1; DIMETHYLNITROSAMINE; ETHOXYRESORUFIN DEETHYLASE; PENTOXYRESORUFIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE FERRIHEMOPROTEIN REDUCTASE;

ARTICLE; COMPLEX FORMATION; DEALKYLATION; DEMETHYLATION; ENZYME KINETICS; IONIC STRENGTH; MOLECULAR MODEL; PRIORITY JOURNAL; PROTEIN ISOLATION;

ANIMALS; ARYL HYDROCARBON HYDROXYLASES; BINDING, COMPETITIVE; CYTOCHROME P-450 CYP1A2; CYTOCHROME P-450 CYP2E1; DEALKYLATION; ELECTROSTATICS; MODELS, CHEMICAL; MODELS, MOLECULAR; MULTIENZYME COMPLEXES; OSMOLAR CONCENTRATION; OXAZINES; PROTEIN INTERACTION MAPPING; RABBITS;

EID: 33845926635     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi061803n     Document Type: Article

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