Biophysical microenvironment and 3D culture physiological relevance

Drug Discovery Today

Volumn 18, Issue 11-12, 2013, Pages 533-540

  Asthana, Amish ^a   Kisaalita, William S ^a  

^a University of Georgia   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALGINIC ACID; COLLAGEN; COLLAGEN TYPE 1; CYTOTOXIC AGENT; LAMININ; MATRIGEL; POLYSTYRENE;

CELL INTERACTION; CELL VIABILITY; DRUG DEVELOPMENT; ELASTICITY; FORCE; HIGH THROUGHPUT SCREENING; HUMAN; IN VITRO STUDY; LIVER CELL; MICROENVIRONMENT; MUSCLE TISSUE; PLIABILITY; REVIEW; SHEAR STRESS; STRESS FIBER;

ANIMALS; BIOPHYSICAL PHENOMENA; CELL CULTURE TECHNIQUES; DRUG DISCOVERY; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS;

EID: 84878825502     PISSN: 13596446     EISSN: 18785832     Source Type: Journal    
DOI: 10.1016/j.drudis.2012.12.005     Document Type: Review

References (79)

1. W.S. Kisaalita 3D Cell-Based Biosensors in Drug Discovery Programs: Microtissue Engineering for High Throughput Screening 2010 CRC Press, Taylor & Francis Group Boca Raton, FL
2. L.G. Griffith, and M.A. Swartz Capturing complex 3D tissue physiology in vitro Nat. Rev. Mol. Cell Biol. 7 2006 211 224
3. J.A. Green, and K.M. Yamada Three-dimensional microenvironments moderate fibroblast signaling responses Adv. Drug Deliv. Rev. 59 2007 1289 1293
4. Y. Lai Biomarkers for simplifying HTS 3D cell culture platforms for drug discovery: the case for cytokines Drug Discov. Today 16 2011 293 297
5. J. Debnath, and J.S. Brugge Modelling glandular epithelial cancers in three-dimensional cultures Nat. Rev. Cancer 5 2005 75 688
6. J.B. do Amaral Cell death and lumen formation in spheroids of MCF-7 cells Cell Biol. Int. 34 2010 267 274
7. F. Grinnell Differences in the regulation of fibroblast contraction of floating versus stressed collagen matrices J. Biol. Chem. 274 1999 918 923
8. M.J. Paszek Tensional homeostasis and the malignant phenotype Cancer Cell 8 2005 241 254
9. A. Asthana, and W.S. Kisaalita Microtissue size and hypoxia in HTS with 3D cultures Drug Discov. Today 2012 10.1016/j.drudis.2012.03.004
10. A.A. Chen Modulation of hepatocyte phenotype in vitro via chemomechanical tuning of polyelectrolyte multilayers Biomaterials 30 2009 1113 1120
11. Y. Lai, and W.S. Kisaalita Performance evaluation of 3D polystyrene 96-well plates with human neural stem cells in a calcium assay J. Lab. Autom. 17 2012 284 292
12. J.Y. Lim, and H.J. Donahue Cell sensing and response to micro- and nanostructured surfaces produced by chemical and topographic patterning Tissue Eng. 13 2007 1879 1891
13. K. Cheng Three-dimensional polymer scaffolds for high throughput cell-based assay systems Biomaterials 29 2008 2802 2812
14. Y. Lai Neural cell 3D microtissue formation is marked by cytokines' up-regulation PLoS ONE 6 2011 E26821
15. A.L. Hubbard Hepatocyte surface polarity I.M. Arias, J.L. Boyer, N. Fausto, W.B. Jakoby, D. Schachter, D. Shafritz, The Liver: Biology and Pathobiology 1994 Raven Press New York
16. M. Maurice Formation of plasma membrane domains in rat hepatocytes and hepatoma cell lines in culture J. Cell Sci. 90 1988 79 92
17. P.V. Moghe Culture matrix configuration and composition in the maintenance of hepatocytes polarity and function Biomaterials 17 1996 373 385
18. E.L. LeCluyse Formation of extensive canalicular networks by rat hepatocytes cultured in collagen-sandwich configuration Am. J. Physiol. 266 1994 C1764 C1774
19. E. Knop Ultrastructural and functional differentiation of hepatocytes under long-term culture conditions Anat. Rec. 242 1995 337 349
20. F.J. Wu Enhanced cytochrome P450 1A1 activity of self-assembled rat hepatocyte spheroids Cell Transplant. 8 1999 233 246
21. Tong Long-term culture of rat liver cell spheroids in hormonally defined media Exp. Cell Res. 189 1990 87 92
22. N. Koide Formation of multicellular spheroids composed of adult rat hepatocytes in dishes with positively charged surfaces and under other nonadherent environments Exp. Cell Res. 186 1990 27 235
23. J. Landry Spheroidal aggregate culture of rat liver cells: histotypic reorganization, biomatrix deposition, and maintenance of functional activities J. Cell Biol. 101 1985 914 923
24. F.J. Wu Efficient assembly of primary rat hepatocyte spheroids for tissue engineering applications Biotechnol. Bioeng. 50 1996 404 415
25. S. Wilkening Comparison of primary human hepatocytes and hepatoma cell line HepG2 with regard to their biotransformation properties Drug Metab. Dispos. 31 2003 1035 1042
26. M. Ek Expression of drug metabolizing enzymes in hepatocyte-like cells Chem. Pharmacol. 74 2007 496 503
27. T. Lynch, and A. Price The effect of cytochrome P450 metabolism on drug response, interactions and adverse effects Am. Fam. Phys. 76 2007 391 396
28. M. Kawamura Jr., and M. Kawamura Long-term facilitation of spontaneous calcium oscillations in astrocytes with endogenous adenosine in hippocampal slice cultures Cell Calcium 49 2011 249 258
29. 2+ oscillations and cell migration Glia 55 2007 652 662
30. T. Numakawa Brain-derived neurotrophic factor-induced potentiation of Ca(2+) oscillations in developing cortical neurons J. Biol. Chem. 277 2002 6520 6529
31. 2+ in cultured rat embryonic hippocampal neurons using a fluorescence microplate reader: potential application to biomolecular screening J. Pharmacol. Toxicol. Methods 49 2004 81 87
32. 2+ to gene expression Gen. Comp. Endocrinol. 169 2010 123 129
33. T.A. Dunn, and M.B. Feller Imaging second messenger dynamics in developing neural circuits Dev. Neurobiol. 68 2008 835 844
34. A.C. Charles Intercellular calcium waves in neurons Mol. Cell. Neurosci. 7 1996 337 353
35. J.L. Costantin, and A.C. Charles Spontaneous action potentials initiate rhythmic intercellular calcium waves in immortalized hypothalamic (GT1-1) neurons J. Neurophysiol. 82 1999 429 435
36. M. Tomić Characterization of plasma membrane calcium oscillator in rat pituitary somatotrophs J. Biol. Chem. 274 1999 5693 35702
37. K.A. Simeone L-Type calcium channel blockade reduces network activity in human epileptic hypothalamic hematoma tissue Epilepsia 52 2011 531 540
38. B. Fermini, and A.A. Fossa The impact of drug-induced QT interval prolongation on drug discovery and development Nat. Rev. Drug Discov. 2 2003 39 447
39. J.M. Kelm Design of artificial myocardial microtissues Tissue Eng. 10 2004 201 214
40. R.K. Li In vivo survival and function of transplanted rat cardiomyocytes Circ. Res. 78 1996 283 288
41. F. Er Dominant-negative suppression of HCN channels markedly reduces the native pacemaker current If and undermines spontaneous beating of neonatal cardiomyocytes Circulation 107 2003 485 489
42. G. Michels Long-term and immediate effect of testosterone on single T-type calcium channel in neonatal rat cardiomyocytes Endocrinology 147 2006 5160 5169
43. W.H. Zimmermann Three-dimensional engineered heart tissue from neonatal rat cardiac myocytes Biotechnol. Bioeng. 68 2000 106 114
44. S. Wiechert 24-h Langendorff-perfused neonatal rat heart used to study the impact of adenoviral gene transfer Am. J. Physiol. Heart Circ. Physiol. 285 2003 H907 H914
45. A.Y. Hsiao 384 hanging drop arrays give excellent Z-factors and allow versatile formation of co-culture spheroids Biotechnol. Bioeng. 109 2012 1293 1304
46. Y. Lai, and W. Kisaalita Performance evaluation of 3D polystyrene 96-well plates with human stem cells and the calcium assay J. Lab. Autom. 17 2012 284 292
47. Y.C. Tung High-throughput 3D spheroid culture and drug testing using a 384 hanging drop array Analyst 136 2011 473 478
48. C. Selden Three-dimensional in vitro cell culture leads to a marked upregulation of cell function in human hepatocyte cell lines-an important tool for the development of a bioartificial liver machine Ann. NY Acad. Sci. 875 1999 353 363
49. E. Chen Young's modulus measurements of soft tissues with application to elasticity imaging IEEE Trans. Ultra Ferro. Freq. Control 43 1996 191 194
50. M. Bokhari Culture of HepG2 liver cells on three dimensional polystyrene scaffolds enhances cell structure and function during toxicological challenge J. Anat. 211 2007 567 576
51. M. Bokhari Novel cell culture device enabling three-dimensional cell growth and improved cell function Biochem. Biophys. Res. Commun. 354 2007 1095 1100
52. S. Sharma Influence of substrates on hepatocytes: a nanomechanical study J. Scann. Probe Microsc. 4 2009 7 16
53. C. Yin Adhesion contact dynamics of HepG2 cells on galactose-immobilized substrates Biomaterials 24 2003 837 850
54. J. Bierwolf Primary rat hepatocyte culture on 3D nanofibrous polymer scaffolds for toxicology and pharmaceutical research Biotechnol. Bioeng. 108 2011 141 150
55. B.E. Uygun Organ reengineering through development of a transplantable recellularized liver graft using decellularized liver matrix Nat. Med. 16 2010 814 820
56. T.T. Chang, and M. Hughes-Fulford Monolayer and spheroid culture of human liver hepatocellular carcinoma cell line cells demonstrate distinct global gene expression patterns and functional phenotypes Tissue Eng. A 14 2008 1 9
57. S.F. Abu-Absi Structural polarity and functional bile canaliculi in rat hepatocyte spheroids Exp. Cell Res. 274 2002 56 67
58. D. Discher Tissue cells feel and respond to the stiffness of their substrate Science 310 2005 1139 1143
59. P.C. Georges Matrices with compliance comparable to that of brain tissue select neuronal over glial growth in mixed cortical cultures Biophys. J. 90 2006 3012 3018
60. T. Yeung Effects of substrate stiffness on cell morphology, cytoskeletal structure, and adhesion Cell Motil. Cytoskeleton 60 2005 24 34
61. J.M. Crawford Imaging biliary lipid secretion in the rat: ultrastructural evidence for vesiculation of the hepatocyte canalicular membrane J. Lipid Res. 36 1995 2147 2163
62. S.S. Soofi The elastic modulus of Matrigel as determined by atomic force microscopy J. Struct. Biol. 167 2009 216 219
63. J.L. Vanderhooft Rheological properties of cross-linked hyaluronan-gelatin hydrogels for tissue engineering Macromol. Biosci. 9 2009 20 28
64. E.R. West Physical properties of alginate hydrogels and their effects on in vitro follicle development Biomaterials 28 2007 4439 4448
65. E.J. Leon Mechanical properties of a self-assembling oligopeptide matrix J. Biomater. Sci. Polym. Ed. 9 1998 297 312
66. J.S. Choi Fabrication of porous extracellular matrix scaffolds from human adipose tissue Tissue Eng. C 16 2010 387 396
67. S.R. Peyton The use of poly(ethylene glycol) hydrogels to investigate the impact of ECM chemistry and mechanics on smooth muscle cells Biomaterials 27 2006 4881 4893
68. V.M. Ayres Scanning probe recognition microscopy investigation of neural cell prosthetic properties Int. J. Nanomanuf. 6 2010 279 290
69. L. Olah Synthesis, structural and mechanical properties of porous polymeric scaffolds for bone tissue regeneration based on neat poly(epison-caprolactone) and its composites with calcium carbonate Polym. Adv. Technol. 17 2006 889 897
70. S.C. Baker Characterisation of electrospun polystyrene scaffolds for three-dimensional in vitro biological studies Biomaterials 27 2006 3136 3146
71. J.C. Zhang Fabrication of three dimensional polymeric scaffolds with spherical pores J. Mater. Sci. 41 2006 1725 1731
72. C.X. Wang Influence of sintering temperatures on hardness and Young's modulus of tricalcium phosphate bioceramic by nanoindentation technique Mater. Charact. 52 2004 301 307
73. A.C. Ripoche Evaluation of nisin diffusion in a polysaccharide gel: influence of agarose and fatty content Innov. Food Sci. Emerg. Technol. 7 2006 107 111
74. R. Sudo Reconstruction of 3D stacked-up structures by rat small hepatocytes on microporous membranes FASEB J. 19 2005 1695 1717
75. M. Khalil Human hepatocyte cell lines proliferating as cohesive spheroid colonies in alginate markedly upregulate both synthetic and detoxificatory liver function J. Hepatol. 297 2001 68 77
76. C.E. Semino Functional differentiation of hepatocyte-like spheroid structures from putative liver progenitor cells in three-dimensional peptide scaffolds Differentiation 71 2003 262 270
77. M.V. Risbud Hydrogel-coated textile scaffolds as candidate in liver tissue engineering. II. Evaluation of spheroid formation and viability of hepatocytes J. Biomater. Sci. Polym. Ed. 14 2003 719 731
78. E. Eschbach Microstructured scaffolds for liver tissue cultures of high cell density: morphological and biochemical characterization of tissue aggregates J. Cell Biochem. 95 2005 243 255
79. H. Huang Enhanced functional maturation of fetal porcine hepatocytes in three-dimensional poly-l-lactic acid scaffolds: a culture condition suitable for engineered liver tissues in large-scale animal studies Cell Transplant. 15 2006 799 809