Three-dimensional microenvironments modulate fibroblast signaling responses

Advanced Drug Delivery Reviews

Volumn 59, Issue 13, 2007, Pages 1293-1298

  Green, J Angelo ^a   Yamada, Kenneth M ^a  

^a NATIONAL INSTITUTE OF DENTAL AND CRANIOFACIAL RESEARCH   (United States)

Author keywords

Fibroblast; Fibronectin; Integrin signaling; Rho GTPases; Three dimensional matrix

Indexed keywords

CELL CULTURE; MATRIX ALGEBRA; SIGNALING; THREE DIMENSIONAL;

CELL BEHAVIOR; DRUG RESPONSES; INTEGRIN SIGNALING; RHO GTPASES;

FIBROBLASTS;

ARGINYLGLYCYLASPARTIC ACID; COLLAGEN; FIBRONECTIN; FOCAL ADHESION KINASE; INTEGRIN; LAMININ; MATRIGEL; MYOSIN II; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE; RAC PROTEIN; RHO GUANINE NUCLEOTIDE BINDING PROTEIN;

ANIMAL CELL; CANCER; CELL ADHESION; CELL FUNCTION; CELL PROLIFERATION; CELL STRAIN 3T3; CELL STRUCTURE; CHEMOTAXIS; CONTROLLED STUDY; EXTRACELLULAR MATRIX; FIBROBLAST; MOUSE; NONHUMAN; PRIORITY JOURNAL; REVIEW; SIGNAL TRANSDUCTION;

CELL MOVEMENT; CELL PROLIFERATION; EXTRACELLULAR MATRIX; EXTRACELLULAR MATRIX PROTEINS; FIBROBLASTS; HUMANS; INTEGRINS; NEOPLASMS; PROTEIN KINASES; SIGNAL TRANSDUCTION; TISSUE SCAFFOLDS;

EID: 36048945388     PISSN: 0169409X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.addr.2007.08.005     Document Type: Review

References (28)

1. Griffith L.G., and Swartz M.A. Capturing complex 3D tissue physiology in vitro. Nat. Rev. Mol. Cell Biol. 7 (2006) 211-224
2. Schindler M., Nur E.K.A., Ahmed I., Kamal J., Liu H.Y., Amor N., Ponery A.S., Crockett D.P., Grafe T.H., Chung H.Y., Weik T., Jones E., and Meiners S. Living in three dimensions: 3D nanostructured environments for cell culture and regenerative medicine. Cell Biochem. Biophys. 45 (2006) 215-227
3. Hynes R.O. Integrins: bidirectional, allosteric signaling machines. Cell 110 (2002) 673-687
4. DeMali K.A., Wennerberg K., and Burridge K. Integrin signaling to the actin cytoskeleton. Curr. Opin. Cell Biol. 15 (2003) 572-582
5. Aota S., Nagai T., and Yamada K.M. Characterization of regions of fibronectin besides the arginine-glycine-aspartic acid sequence required for adhesive function of the cell-binding domain using site-directed mutagenesis. J. Biol. Chem. 266 (1991) 15938-15943
6. Nagai T., Yamakawa N., Aota S., Yamada S.S., Akiyama S.K., Olden K., and Yamada K.M. Monoclonal antibody characterization of two distant sites required for function of the central cell-binding domain of fibronectin in cell adhesion, cell migration, and matrix assembly. J. Cell Biol. 114 (1991) 1295-1305
7. Obara M., Kang M.S., and Yamada K.M. Site-directed mutagenesis of the cell-binding domain of human fibronectin: separable, synergistic sites mediate adhesive function. Cell 53 (1988) 649-657
8. Mao Y., and Schwarzbauer J.E. Accessibility to the fibronectin synergy site in a 3D matrix regulates engagement of alpha 5 beta 1 versus alpha v beta 3 integrin receptors. Cell Commun. Adhes. 13 (2006) 267-277
9. Blystone S.D., Graham I.L., Lindberg F.P., and Brown E.J. Integrin alpha v beta 3 differentially regulates adhesive and phagocytic functions of the fibronectin receptor alpha 5 beta 1. J. Cell Biol. 127 (1994) 1129-1137
10. Blystone S.D., Slater S.E., Williams M.P., Crow M.T., and Brown E.J. A molecular mechanism of integrin crosstalk: alpha v beta 3 suppression of calcium/calmodulin-dependent protein kinase II regulates alpha 5 beta 1 function. J. Cell Biol. 145 (1999) 889-897
11. Diaz-Gonzalez F., Forsyth J., Steiner B., and Ginsberg M.H. Trans-dominant inhibition of integrin function. Mol. Biol. Cell 7 (1996) 1939-1951
12. Ly D.P., Zazzali K.M., and Corbett S.A. De novo expression of the integrin alpha 5 beta 1 regulates alpha v beta 3-mediated adhesion and migration on fibrinogen. J. Biol. Chem. 278 (2003) 21878-21885
13. Grinnell F. Fibroblast biology in three-dimensional collagen matrices. Trends Cell Biol. 13 (2003) 264-269
14. Cukierman E., Pankov R., Stevens D.R., and Yamada K.M. Taking cell-matrix adhesions to the third dimension. Science 294 (2001) 1708-1712
15. Cukierman E., Pankov R., and Yamada K.M. Cell interactions with three-dimensional matrices. Curr. Opin. Cell Biol. 14 (2002) 633-639
16. Pankov R., Endo Y., Even-Ram S., Araki M., Clark K., Cukierman E., Matsumoto K., and Yamada K.M. A Rac switch regulates random versus directionally persistent cell migration. J. Cell Biol. 170 (2005) 793-802
17. Even-Ram S., and Yamada K.M. Cell migration in 3D matrix. Curr. Opin. Cell Biol. 17 (2005) 524-532
18. Discher D.E., Janmey P., and Wang Y.L. Tissue cells feel and respond to the stiffness of their substrate. Science 310 (2005) 1139-1143
19. Nur E.K.A., Ahmed I., Kamal J., Schindler M., and Meiners S. Three dimensional nanofibrillar surfaces induce activation of Rac. Biochem. Biophys. Res. Commun. 331 (2005) 428-434
20. Mao Y., and Schwarzbauer J.E. Stimulatory effects of a three-dimensional microenvironment on cell-mediated fibronectin fibrillogenesis. J. Cell Sci. 118 (2005) 4427-4436
21. Larsen M., Artym V.V., Green J.A., and Yamada K.M. The matrix reorganized: extracellular matrix remodeling and integrin signaling. Curr. Opin. Cell Biol. 18 (2006) 463-471
22. Elsdale T., and Bard J. Collagen substrata for studies on cell behavior. J. Cell Biol. 54 (1972) 626-637
23. Beningo K.A., Dembo M., and Wang Y.L. Responses of fibroblasts to anchorage of dorsal extracellular matrix receptors. Proc. Natl. Acad. Sci. U. S. A. 101 (2004) 18024-18029
24. Wozniak M.A., Desai R., Solski P.A., Der C.J., and Keely P.J. ROCK-generated contractility regulates breast epithelial cell differentiation in response to the physical properties of a three-dimensional collagen matrix. J. Cell Biol. 163 (2003) 583-595
25. Endo Y., Even-Ram S., Pankov R., Matsumoto K., and Yamada K.M. Inhibition of rho GTPases by RNA interference. Methods Enzymol. 406 (2006) 345-361
26. Haugh J.M., Codazzi F., Teruel M., and Meyer T. Spatial sensing in fibroblasts mediated by 3′ phosphoinositides. J. Cell Biol. 151 (2000) 1269-1280
27. Van Haastert P.J., and Devreotes P.N. Chemotaxis: signalling the way forward. Nat. Rev. Mol. Cell Biol. 5 (2004) 626-634
28. Amatangelo M.D., Bassi D.E., Klein-Szanto A.J., and Cukierman E. Stroma-derived three-dimensional matrices are necessary and sufficient to promote desmoplastic differentiation of normal fibroblasts. Am. J. Pathol. 167 (2005) 475-488