Three-dimensional polymer scaffolds for high throughput cell-based assay systems

Biomaterials

Volumn 29, Issue 18, 2008, Pages 2802-2812

  Cheng, Ke ^a   Lai, Yinzhi ^a   Kisaalita, William S ^a  

^a Faculty of Engineering   (United States)

Author keywords

Biomimetic material; Cell culture; ECM; Scaffold; Stem cell

Indexed keywords

BIOASSAY; BIODEGRADABLE POLYMERS; CELL CULTURE; GENE EXPRESSION; PHYSIOLOGY; SCREENING;

CELL-BASED ASSAY; HIGH THROUGHPUT SCREENING (HTS); MULTI-WELL PLATES; SYNTHETIC POLYMER SCAFFOLDS;

BIOMIMETIC MATERIALS;

BIOMIMETIC MATERIAL; POLYMER; VOLTAGE GATED CALCIUM CHANNEL;

ARTICLE; CELL ASSAY; CELL CULTURE; CELL GROWTH; CELL INTERACTION; CELL STRUCTURE; CONTROLLED STUDY; EXTRACELLULAR MATRIX; GENE EXPRESSION; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; NEURAL STEM CELL; PRIORITY JOURNAL; STEM CELL;

BIOCOMPATIBLE MATERIALS; BIOLOGICAL ASSAY; BLOTTING, WESTERN; CELL CULTURE TECHNIQUES; CELL LINE; HUMANS; MICROSCOPY, ELECTRON, SCANNING; NEURONS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; POLYMERS; POROSITY; STEM CELLS; TISSUE SCAFFOLDS;

EID: 42049092773     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2008.03.015     Document Type: Article

References (33)

1. Kunz-Schughart L.A., Freyer J.P., Hofstaedter F., and Ebner R. The use of 3-D cultures for high-throughput screening: the multicellular spheroid model. Journal of Biomolecular Screening 9 (2004) 273-285
2. Bousse L. Whole cell biosensors. Sensors and Actuators 34 (1996) 270-275
3. Abbott A. Biology's new dimension. Nature 424 (2003) 870-872
4. Jessup L.M., Godowin T.J., and Spaulding G.F. Prospects for use of microgravity-based bioreactors to study three dimensional host-tumor interactions in human neoplasia. Journal Cellular Biochemistry 51 (1993) 290-300
5. Desai A., Kisaalita W.S., Keith C., and Wu Z.Z. Human neuroblastoma (SH-SY5Y) cell culture and differentiation in 3-D collagen hydrogels for cell-based biosensing. Biosensors and Bioelectronics 21 (2006) 1483-1492
6. Mao C., and Kisaalita W.S. Characterization of 3-D collagen gels for functional cell-based biosensing. Biosensors and Bioelectronics 19 (2004) 1075-1088
7. Albrecht D.R., Underhill G.H., Wassermann T.B., Sah R.L., and Bhatia S.N. Probing the role of multicellular organization in three-dimensional microenvironments. Nature Methods 3 (2006) 369-375
8. Freed L.E., Vunjak-Novakovic G., Biron R.J., Eagles D.B., Lesnoy D.C., Barlow S.K., et al. Biodegradable polymer scaffolds for tissue engineering. Nature Biotechnology 12 (1994) 689-693
9. Simon Jr. C.G., Stephens J.S., Dorsey S.M., and Becker M.L. Fabrication of combinatorial polymer scaffold libraries. Review of Scientific Instruments 78 (2007) 0722071-0722077
10. Zhang S. Beyond the Petri dish. Nature Biotechnology 22 (2004) 151-152
11. Powers M.J., Domansky K., Kaazempur-Mofrad M.R., Kalezi A., Capitano A., Upadhyaya A., et al. A microfabricated array bioreactor for perfused 3D liver culture. Biotechnology and Bioengineering 78 (2002) 257-269
12. Xu T., Gregory C.A., Molnar P., Cui X., Jalota S., Bhaduri S.B., et al. Viability and electrophysiology of neural cell structures generated by the inkjet printing method. Biomaterials 27 19 (2006) 3580-3588
13. Freyman T.M., Yannas I.V., and Gibson L.J. Cellular materials as porous scaffolds for tissue engineering. Progress in Materials Science 46 (2001) 273-282
14. Zhang R., and Ma P.X. Poly(alpha-hydroxyl acids)/hydroxyapatite porous composites for bone-tissue engineering. I. Preparation and morphology. Journal of Biomedical Materials Research 44 (1999) 446-455
15. Wu Z.Z., Zhao Y.P., and Kisaalita W.S. A packed Cytodex microbead array for three-dimensional cell-based biosensing. Biosensors and Bioelectronics 22 5 (2006) 685-693
16. Wang S.S., and Good T.A. Effect of culture in a rotating wall bioreactor on the physiology of differentiated neuron-like PC12 and SH-SY5Y cells. Journal Cellular Biochemistry 83 (2001) 574-584
17. Kunz-Schughart L.A., Kreutz M., and Knuechel R. Multicellular spheroids: a three-dimensional in vitro culture system to study tumor biology. International Journal of Experimental Pathology 79 (1998) 1-23
18. Wang H.B., Dembo M., Hanks S.K., and Wang Y. Focal adhesion kinase is involved in mechanosensing during fibroblast migration. Proceedings of the National Academy of Sciences of the United States of America 98 20 (2001) 11295-11300
19. Cukierman E., Pankov R., Stevens D.R., and Yamada K.M. Taking cell-matrix adhesions to the third dimension. Science 294 (2001) 1708-1712
20. Wozniak M.A., Desai R., Solski P.A., Der C.J., and Keely P.J. Rock generated contractility regulates beast epithelial cell differentiation in response to the physical properties of a three-dimensional collagen matrix. Journal of Cell Biology 163 3 (2003) 583-595
21. Klapperich C.M., and Bertozzi C.R. Global gene expression of cells attached to a tissue engineering scaffold. Biomaterials 25 (2004) 5631-5641
22. Shibuya M. Structure and function of VEGF/VEGF-receptor system involved in angiogenesis. Cell Structure and Function 26 (2001) 25-35
23. Palmer T.D., Willhoite A.R., and Gage F.H. Vascular niche for adult hippocampal neurogenesis. Journal of Comparative Neurology 425 (2000) 479-494
24. Leventhal C., Rafii D., Shahar A., and Goldman S.A. Endothelial trophic support of neuronal production and recruitment from the adult mammalian subependyma. Molecular Cell Neuroscience 13 (1999) 450-464
25. Khaibullina A.A., Rosenstein J.M., and Krum J.M. Vascular endothelia growth factor promotes neurite maturation in primary CNS neuronal cultures. Developmental Brain Research 148 (2004) 59-68
26. Meng H., Zhang Z., Zhang R., Liu X., Wang L., Robin A.M., et al. Biphasic effects of exogenous VEGF on VEGF expression of adult neural progenitors. Neuroscience Letters 393 2-3 (2006) 97-101
27. Martinez-Pinna J., Lamas J.A., and Gallego R. Calcium current components in intact and dissociated adult mouse sympathetic neurons. Brain Research 951 (2002) 227-236
28. Matsukawa A., Lukacs N.W., Hogaboam C.M., Chensue S.W., and Kunkel III S.L. Chemokines and other mediators, 8. Chemokines and their receptors in cell-mediated immune responses in the lung. Microscopy Research and Technique 53 (2001) 298-306
29. 2+ currents in identified cholinergic septal neurons expressing CXCR1 and CXCR2 receptor mRNAs. Journal of Neurochemistry 78 5 (2001) 960-971
30. Denyer J., Worley J., Cox B., Allenby G., and Banks M. HTS approaches to voltage-gated ion channel drug discovery. Drug Discovery Today 3 (1998) 323-332
31. Angelo-Green J, Yamada KM. Three dimensional microenvironments modulate fibroblast signaling responses. Advanced Drug Delivery Reviews, in press.
32. Anders M., Hansen R., Ding R.X., Rauen K.A., Bissell M.J., and Michael-Korn W. Disruption of 3D tissue integrity facilitates adenovirus infection by deregulating the coxsackievirus and adenovirus receptor. Proceedings of the National Academy of Sciences of the United States of America 100 4 (2003) 1943-1948
33. Weaver V.M., Petersen O.W., Wang F., Larabell C.A., Briand P., Damsky C., et al. Reversion of the malignant phenotype of human breast cells in three-dimensional culture and in vivo by integrin blocking antibodies. Journal of Cell Biology 137 (1997) 231-245