Synthesis, structural and mechanical properties of porous polymeric scaffolds for bone tissue regeneration based on neat poly(ε-caprolactone) and its composites with calcium carbonate

Polymers for Advanced Technologies

Volumn 17, Issue 11-12, 2006, Pages 889-897

  Olah, Laszlo ^a,b   Filipczak, Katarzyna ^a   Jaegermann, Zbigniew ^c   Czigany, Tibor ^b   Borbas, Lajos ^d   Sosnowski, Stanislaw ^d   Ulanski, Piotr ^a   Rosiak, Janusz M ^a  

^a LODZ UNIVERSITY OF TECHNOLOGY   (Poland)

^b BUDAPEST UNIVERSITY OF TECHNOLOGY AND ECONOMICS   (Hungary)

^c Institute of Glass and Ceramics   (Poland)

^d CENTRE OF MOLECULAR AND MACROMOLECULAR STUDIES   (Poland)

Author keywords

Biomaterials; Composites; Macroporous polymers; Mechanical properties; Synthesis

Indexed keywords

BONE; CALCIUM COMPOUNDS; MECHANICAL PROPERTIES; POLYMERS; POROSITY; STRUCTURAL ANALYSIS; SYNTHESIS (CHEMICAL); TISSUE;

BONE TISSUE REGENERATION; CALCIUM CARBONATE; MACROPOROUS POLYMERS; POLYCAPROLACTONE; POLYMERIC SCAFFOLDS;

BIOMATERIALS;

BIOMATERIALS; BONE; CALCIUM COMPOUNDS; MECHANICAL PROPERTIES; POLYMERS; POROSITY; STRUCTURAL ANALYSIS; SYNTHESIS (CHEMICAL); TISSUE;

BIODEGRADABILITY; BONE REPAIR; MECHANICAL PROPERTY; POLYCAPROLACTONE; POROSITY; SCANNING ELECTRON MICROSCOPY; STRUCTURAL PROPERTY; SYNTHESIS; TESTING; TISSUE ENGINEERING;

EID: 33846382446     PISSN: 10427147     EISSN: 10991581     Source Type: Journal    
DOI: 10.1002/pat.768     Document Type: Conference Paper

References (19)

1. Lieberman JR, Friedlaender GE. Bone Regeneration and Repair, Biology and Clinical Applications. Humana Press: New Jersey, 2005.
2. Goldberg VM, Caplan AI. Orthopedic Tissue Engineering, Basic Science and Practice. Marcel Dekker: New York, 2004.
3. Ramakrishna S, Mayer J, Wintermantel E, Leong KW. Biomedical applications of polymer-composite materials: a review. Compos. Sci. Technol. 2001; 61: 1189-1224.
4. Calandrelli L, Immirzi B, Malinconicon M, Luessenheide S, Passaro I, di Pasquale R, Oliva A. Natural and synthetic hydroxyapatite filled PCL: mechanical properties and biocompatibility analysis. J. Bioactive and Compatible Polym. 2004; 19: 301-313.
5. Bronzino JD. The Biomedical Engineering Handbook (2nd edn) CRC Press LLC: Boca Raton, FL, 2000.
6. Rieu J, Goeuriot P. Ceramic composites for biomedical applications. Clin. Mater. 1993; 12: 211-217.
7. Kasuga T, Maeda H, Kato K, Nogami M, Hata K, Ueda M. Preparation of poly(lactic acid) composites containing calcium carbonate (vaterite). Biomaterials 2003; 24: 3247-3253.
8. Fujihara K, Kotaki M, Ramakrishna S. Guided bone regeneration membrane made of polycaprolactone/calcium carbonate composite nano-fibers. Biomaterials 2005; 26: 4139-4147.
9. Shikinami Y, Okuno M. Bioresorbable devices made of forged composites of hydroxyapatite (HA) particles and poly l-lactide (PLLA), Part II: practical properties of miniscrews and miniplates. Biomaterials 2001; 22: 3197-3211.
10. Ural E, Kesenci K, Fambri L, Migliaresi C, Piskin E. Poly(d,l-lactide/ ε-caprolactone) /hydroxyapatite composites. Biomaterials 2001; 21: 2147-2154.
11. Kweon HY, Yoo MK, Park IK, Kim TH, Lee HC, Lee HS, Oh JS, Akaike T, Cho CS. A novel degradable polycaprolactone network for tissue engineering. Biomaterials 2001; 24: 801-808.
12. Walsh WR, Chapman-Sheath PJ, Cain S, Debes J, Bruce WJM, Svehla MJ, Gillies RM. A resorbable porous ceramic composite bone graft substitute in a rabbit methaphyseal defect model. J. Orthopaedic Research 2003; 21: 655-661.
13. Vago R, Plotquin D, Bunin A, Sinelnikov I, Atar D, Itzhak D. Hard tissue remodeling using biofabricated coralline biomaterials. J. Biochem. Biophys. Methods 2002; 50: 253-259.
14. Liao H, Mutvei H, Sjostrom M, Hammarstrom L, Li J. Tissue responses to natural aragonite (Margaritifera shell) implants in vivo. Biomaterials 2000; 21: 457-468.
15. Filipczak K, Janik I, Kozicki M, Ulanski P, Rosiak JM, Pajewski LA, Olkowski R, Woźniak P, Chroscicka A, Lewandowska-Szumiel M. Porous polymeric scaffolds for bone regeneration. e-Polymers 2005; 011.
16. Gachter R, Müller H. Plastics Additives Handbook. Hanser Publisher: München, 1990.
17. Serrano MC, Pagani R, Vallet-Regi M, Pena J, Rámila A, Izquierdo I, Portolés MT. In vitro biocompatibility assessment of poly(ε-caprolatone) films using L929 mouse fibroblast. Biomaterials 2004; 25: 5603-5611.
18. Chawla KK. Composite Materials, Science and Engineering (2nd edn). Springer: New York, 2001.
19. Schiller C, Rasche C, Wehmöller M, Beckmann F, Eufinger H, Epple M, Weihe S. Geometrically structured implants for cranial reconstruction made of biodegradable polyesters and calcium phosphate/calcium carbonate. Biomaterials 2004; 25: 1239-1247.