-
1
-
-
77954074097
-
Predicting the network of substrate-enzyme-product triads by combining compound similarity and functional domain composition
-
Chen, L.; Feng, K.Y.; Cai, Y.D.; Chou, K.C.; Li, H.P. Predicting the network of substrate-enzyme-product triads by combining compound similarity and functional domain composition. BMC Bioinformatics, 2010, 11, 293.
-
(2010)
BMC Bioinformatics
, vol.11
, pp. 293
-
-
Chen, L.1
Feng, K.Y.2
Cai, Y.D.3
Chou, K.C.4
Li, H.P.5
-
2
-
-
84876053736
-
IRSpot-PseDNC: Identify recombination spots with pseudo dinucleotide composition
-
open accessible with doi:101093/nar/gks1450
-
[] Chen, W.; Feng, P.M.; Lin, H.; Chou, K.C. iRSpot-PseDNC: identify recombination spots with pseudo dinucleotide composition. Nucleic Acids Res, 2013, 41, e68 (open accessible with doi:101093/nar/gks1450).
-
(2013)
Nucleic Acids Res
, vol.41
, pp. 68
-
-
Chen, W.1
Feng, P.M.2
Lin, H.3
Chou, K.C.4
-
3
-
-
80051676719
-
NR-2L: A two-level predictor for identifying nuclear receptor subfamilies based on sequence-derived features
-
Wang, P.; Xiao, X.; Chou, K.C. NR-2L: A two-level predictor for identifying nuclear receptor subfamilies based on sequence-derived features. PLoS ONE, 2011, 6(8), e23505.
-
(2011)
PLoS ONE
, vol.6
, Issue.8
-
-
Wang, P.1
Xiao, X.2
Chou, K.C.3
-
4
-
-
0027219970
-
A vectorized sequence-coupling model for predicting HIV protease cleavage sites in proteins
-
Chou, K.C. A vectorized sequence-coupling model for predicting HIV protease cleavage sites in proteins. J Biol Chem, 1993, 268(23), 16938-48.
-
(1993)
J Biol Chem
, vol.268
, Issue.23
, pp. 16938-16948
-
-
Chou, K.C.1
-
5
-
-
0030049315
-
Prediction of human immunodeficiency virus protease cleavage sites in proteins
-
Chou, K.C. Prediction of human immunodeficiency virus protease cleavage sites in proteins. Anal Biochem, 1996, 233(1), 1-14.
-
(1996)
Anal Biochem
, vol.233
, Issue.1
, pp. 1-14
-
-
Chou, K.C.1
-
6
-
-
40649104302
-
HIVcleave: A web-server for predicting HIV protease cleavage sites in proteins
-
Shen, H.B; Chou, K.C. HIVcleave: a web-server for predicting HIV protease cleavage sites in proteins. Anal Biochem, 2008, 375(2), 388-90.
-
(2008)
Anal Biochem
, vol.375
, Issue.2
, pp. 388-390
-
-
Shen, H.B.1
Chou, K.C.2
-
7
-
-
79951606205
-
GPCR-2L: Predicting G proteincoupled receptors and their types by hybridizing two different modes of pseudo amino acid compositions
-
Xiao, X.; Wang, P.; Chou, K.C. GPCR-2L: Predicting G proteincoupled receptors and their types by hybridizing two different modes of pseudo amino acid compositions. Mol Biosyst, 2011, 911-9.
-
(2011)
Mol Biosyst
, pp. 911-919
-
-
Xiao, X.1
Wang, P.2
Chou, K.C.3
-
8
-
-
53149132374
-
ProtIdent: A web server for identifying proteases and their types by fusing functional domain and sequential evolution information
-
Chou, K.C.; Shen, H.B. ProtIdent: A web server for identifying proteases and their types by fusing functional domain and sequential evolution information. Biochem Biophys Res Commun, 2008, 376(2), 321-5.
-
(2008)
Biochem Biophys Res Commun
, vol.376
, Issue.2
, pp. 321-325
-
-
Chou, K.C.1
Shen, H.B.2
-
9
-
-
84859298511
-
Identification of colorectal cancer related genes with mRMR and shortest path in protein-protein interaction network
-
Li, B.Q.; Huang, T.; Liu, L.; Cai, Y. D.; Chou, K. C. Identification of colorectal cancer related genes with mRMR and shortest path in protein-protein interaction network. PLoS One, 2012, 7(4), e33393.
-
(2012)
PLoS One
, vol.7
, Issue.4
-
-
Li, B.Q.1
Huang, T.2
Liu, L.3
Cai, Y.D.4
Chou, K.C.5
-
10
-
-
84859499974
-
Hepatitis C virus netwok based classification of hepatocellular cirrhosis and carcinom
-
Huang, T.; Wang, J.; Cai, Y.D.; Yu, H.; Chou, K.C. Hepatitis C virus network based classification of hepatocellular cirrhosis and carcinoma. PLoS One, 2012, 7(4), e34460.
-
(2012)
PLoS On
, vol.7
, Issue.4
-
-
Huang, T.1
Wang, J.2
Cai, Y.D.3
Yu, H.4
Chou, K.C.5
-
11
-
-
84870044593
-
Predicting secretory proteins of malaria parasite by incorporating sequence evolution information into pseudo amino acid composition via grey system model
-
Lin, W.Z.; Fang, J.A.; Xiao, X.; Chou, K.C. Predicting secretory proteins of malaria parasite by incorporating sequence evolution information into pseudo amino acid composition via grey system model. PLoS One, 2012, 7(11), e49040.
-
(2012)
PLoS One
, vol.7
, Issue.11
-
-
Lin, W.Z.1
Fang, J.A.2
Xiao, X.3
Chou, K.C.4
-
12
-
-
84855641685
-
-
Chou, K.C.; Wu, Z.C.; Xiao, X. iLoc-Hum: Using accumulationlabel scale to predict subcellular locations of human proteins with both single and multiple sites.;Mol Biosyst, 2012, 8(2), 629-41.
-
(2012)
ILoc-Hum: Using Accumulationlabel Scale to Predict Subcellular Locations of Human Proteins With Both Single and Multiple Sites. Mol Biosyst
, vol.8
, Issue.2
, pp. 629-641
-
-
Chou, K.C.1
Wu, Z.C.2
Xiao, X.3
-
13
-
-
84877758233
-
Some Remarks on Predicting Multi-Label Attributes in Molecular Biosystems
-
Chou, K.C. Some Remarks on Predicting Multi-Label Attributes in Molecular Biosystems. Mol Biosyst, 2013, 9, 1092-1100.
-
(2013)
Mol Biosyst
, vol.9
, pp. 1092-1100
-
-
Chou, K.C.1
-
14
-
-
58749107670
-
Approach to antimicrobials. 4. Multi-target QSAR modeling and comparative multidistance study of the giant components of antiviral drug-drug complex networks
-
Prado-Prado, F.J.; Martinez, V.O.; Uriarte, E.; Ubeira, F.M.; Chou, K.C.; González-Díaz, H. Unified QSAR approach to antimicrobials. 4. Multi-target QSAR modeling and comparative multidistance study of the giant components of antiviral drug-drug complex networks. Bioorg Med Chem, 2009, 17(2), 569-75.
-
(2009)
Bioorg Med Chem
, vol.17
, Issue.2
, pp. 569-575
-
-
Prado-Prado, F.J.1
Martinez, V.O.2
Uriarte, E.3
Ubeira, F.M.4
Chou, K.C.5
González-Díaz, H.6
Unified, Q.S.A.R.7
-
15
-
-
58249089596
-
Fragment-based quantitative structure-activity relationship (FB-QSAR) for fragment-based drug design
-
Du, Q.S.; Huang, R.B.; Wei, Y.T.; Pang, Z.W.; Du, L.Q.; Chou, K.C. Fragment-based quantitative structure-activity relationship (FB-QSAR) for fragment-based drug design. J Comput Chem, 2009, 30(2), 295-304.
-
(2009)
J Comput Chem
, vol.30
, Issue.2
, pp. 295-304
-
-
Du, Q.S.1
Huang, R.B.2
Wei, Y.T.3
Pang, Z.W.4
Du, L.Q.5
Chou, K.C.6
-
16
-
-
77649339280
-
Review: Recent advances in developing web-servers for predicting protein attributes
-
doi: 10.4236/ns.2009. 12011, (openly accessible at
-
] Chou, K.C.; Shen, H.B. Review: recent advances in developing web-servers for predicting protein attributes (doi: 10.4236/ns.2009. 12011). Natural Science, 2009, 2, 63-92. (openly accessible at http://www.scirp.org/journal/NS/)
-
(2009)
Natural Science
, vol.2
, pp. 63-92
-
-
Chou, K.C.1
Shen, H.B.2
-
17
-
-
3242792729
-
Review: Structural bioinformatics and its impact to biomedical science
-
[] Chou, K.C. Review: Structural bioinformatics and its impact to biomedical science. Curr Med Chem, 2004, 11(16), 2105-34.
-
(2004)
Curr Med Chem
, vol.11
, Issue.16
, pp. 2105-2134
-
-
Chou, K.C.1
-
18
-
-
84862004194
-
Design novel dual agonists for treating type-2 diabetes by targeting peroxisome proliferator-activated receptors with core hopping approach
-
Ma, Y.; Wang, S.Q.; Xu, W.R.; Wang, R.L.; Chou, K.C. Design novel dual agonists for treating type-2 diabetes by targeting peroxisome proliferator-activated receptors with core hopping approach. PLoS One, 2012, 7(6), e38546.
-
(2012)
PLoS One
, vol.7
, Issue.6
-
-
Ma, Y.1
Wang, S.Q.2
Xu, W.R.3
Wang, R.L.4
Chou, K.C.5
-
19
-
-
82455181447
-
Novel inhibitor design for hemagglutinin against H1N1 influenza virus by core hopping method
-
Li, X.B.; Wang, S.Q.; Xu, W.R.; Wang, R.L.; Chou, K.C. Novel inhibitor design for hemagglutinin against H1N1 influenza virus by core hopping method. PLoS One, 2011, 6(11), e28111.
-
(2011)
PLoS One
, vol.6
, Issue.11
-
-
Li, X.B.1
Wang, S.Q.2
Xu, W.R.3
Wang, R.L.4
Chou, K.C.5
-
20
-
-
0041848237
-
Binding mechanism of coronavirus main proteinase with ligands and its implication to drug design against SARS
-
Chou, K.C.; Wei, D.Q.; Zhong, W.Z. Binding mechanism of coronavirus main proteinase with ligands and its implication to drug design against SARS. Biochem Biophys Res Commun, 2003, 308(1), 148-51.
-
(2003)
Biochem Biophys Res Commun
, vol.308
, Issue.1
, pp. 148-151
-
-
Chou, K.C.1
Wei, D.Q.2
Zhong, W.Z.3
-
21
-
-
0042835739
-
Synthesis of a first estradioladenosine hybrid compound
-
Poirier, D.; Boivin, R.P.; Bérabé, M.; Lin, S.X. Synthesis of a first estradioladenosine hybrid compound. Synth Commun, 2003, 33(18), 3183-92.
-
(2003)
Synth Commun
, vol.33
, Issue.18
, pp. 3183-3192
-
-
Poirier, D.1
Boivin, R.P.2
Bérabé, M.3
Lin, S.X.4
-
22
-
-
0036831679
-
A concerted, rational design of 17beta-hydroxysteroid dehydrogenase inhibitors: Complex structure with estradiol-adenosine hybrids with high affinity
-
Qiu, W.; Campbell, R.L.; Gangloff, A.; Dupuis, P.; Boivin, P.; Tremblay, M.R.; Poirier, D.; Lin, S.X. A concerted, rational design of 17beta-hydroxysteroid dehydrogenase inhibitors: complex structure with estradiol-adenosine hybrids with high affinity. FASEB J, 2002, 16(13), 1829-31.
-
(2002)
FASEB J
, vol.16
, Issue.13
, pp. 1829-1831
-
-
Qiu, W.1
Campbell, R.L.2
Gangloff, A.3
Dupuis, P.4
Boivin, P.5
Tremblay, M.R.6
Poirier, D.7
Lin, S.X.8
-
23
-
-
60249089957
-
Integrated view on 17beta-hydroxysteroid dehydrogenases
-
Moeller, G.; Adamski, J. Integrated view on 17beta-hydroxysteroid dehydrogenases. Mol Cell Endocrinol, 2009, 301(1-2), 7-19.
-
(2009)
Mol Cell Endocrinol
, vol.301
, Issue.1-2
, pp. 7-19
-
-
Moeller, G.1
Adamski, J.2
-
24
-
-
0034993363
-
Analysis and characteristics of multiple types of human 17beta-hydroxysteroid dehydrogenase
-
Analysis and characteristics of multiple types of human 17beta-hydroxysteroid dehydrogenase. J Steroid Biochem Mol Biol, 2001, 76(1-5), 143-51.
-
(2001)
J Steroid Biochem Mol Biol
, vol.76
, Issue.1-5
, pp. 143-151
-
-
-
25
-
-
61649096847
-
Perspectives in understanding the role of human 17beta-hydroxysteroid dehydrogenases in health and disease
-
Meier, M.; Möller, G.; Adamski, J. Perspectives in understanding the role of human 17beta-hydroxysteroid dehydrogenases in health and disease. Ann N Y Acad Sci, 2009, 1155, 15-24.
-
(2009)
Ann N Y Acad Sci
, vol.1
, pp. 15-24
-
-
Meier, M.1
Möller, G.2
Adamski, J.3
-
26
-
-
79955776935
-
17Hydroxysteroid dehydrogenases (17HSDs) as therapeutic targets: Protein structures, functions, and recent progress in inhibitor development
-
Marchais-Oberwinkler, S.; Henn, C.; Möller, G.; Klein, T.; Negri, M.; Oster, A.; Spadaro, A.; Werth, R.; Wetzel, M.; Xu, K.; Frotscher, M.; Hartmann, R.W.; Adamski, J. 17Hydroxysteroid dehydrogenases (17HSDs) as therapeutic targets: protein structures, functions, and recent progress in inhibitor development. J Steroid Biochem Mol Biol, 2011, 125(1-2), 66-82.
-
(2011)
J Steroid Biochem Mol Biol
, vol.125
, Issue.1-2
, pp. 66-82
-
-
Marchais-Oberwinkler, S.1
Henn, C.2
Möller, G.3
Klein, T.4
Negri, M.5
Oster, A.6
Spadaro, A.7
Werth, R.8
Wetzel, M.9
Xu, K.10
Frotscher, M.11
Hartmann, R.W.12
Adamski, J.13
-
27
-
-
0033852685
-
Intracrinology: Role of the family of 17 beta-hydroxysteroid dehydrogenases in human physiology and disease
-
Labrie, F.; Luu-The, V.; Lin, S.X.; Simard, J.; Labrie, C.; El-Alfy, M.; Pelletier, G.; Bélanger, A. Intracrinology: role of the family of 17 beta-hydroxysteroid dehydrogenases in human physiology and disease. J Mol Endocrinol, 2000, 25(1), 1-16.
-
(2000)
J Mol Endocrinol
, vol.25
, Issue.1
, pp. 1-16
-
-
Labrie, F.1
Luu-The, V.2
Lin, S.X.3
Simard, J.4
Labrie, C.5
El-Alfy, M.6
Pelletier, G.7
Bélanger, A.8
-
28
-
-
0038013585
-
Hydroxysteroid dehydrogenases and pre-receptor regulation of steroid hormone action
-
Penning, T.M. Hydroxysteroid dehydrogenases and pre-receptor regulation of steroid hormone action. Hum Reprod Update, 2003, 9(3), 193-205.
-
(2003)
Hum Reprod Update
, vol.9
, Issue.3
, pp. 193-205
-
-
Penning, T.M.1
-
29
-
-
67349105361
-
Mechanisms of estrogen signaling and gene expression via GPR30
-
Prossnitz, E.R.; Maggiolini, M. Mechanisms of estrogen signaling and gene expression via GPR30. Mol Cell Endocrinol, 2009, 308(1-2), 32-8.
-
(2009)
Mol Cell Endocrinol
, vol.308
, Issue.1-2
, pp. 32-38
-
-
Prossnitz, E.R.1
Maggiolini, M.2
-
30
-
-
14844343093
-
A transmembrane intracellular estrogen receptor mediates rapid cell signaling
-
Revankar, C.M.; Cimino, D.F.; Sklar, L.A.; Arterburn, J.B.; Prossnitz, E.R. A transmembrane intracellular estrogen receptor mediates rapid cell signaling. Science, 2005, 307(5715), 1625-30.
-
(2005)
Science
, vol.307
, Issue.5715
, pp. 1625-1630
-
-
Revankar, C.M.1
Cimino, D.F.2
Sklar, L.A.3
Arterburn, J.B.4
Prossnitz, E.R.5
-
31
-
-
63149166711
-
Recent advances in 17betahydroxysteroid dehydrogenases
-
Prehn, C.; Möller, G.; Adamski, J. Recent advances in 17betahydroxysteroid dehydrogenases. J Steroid Biochem Mol Biol, 2009, 114(1-2), 72-7.
-
(2009)
J Steroid Biochem Mol Biol
, vol.114
, Issue.1-2
, pp. 72-77
-
-
Prehn, C.1
Möller, G.2
Adamski, J.3
-
32
-
-
0037388993
-
Evolution of adrenal and sex steroid action in vertebrates: A ligand-based mechanism for complexity
-
Baker, M.E. Evolution of adrenal and sex steroid action in vertebrates: a ligand-based mechanism for complexity. Bioessays, 2003, 25(4), 396-400.
-
(2003)
Bioessays
, vol.25
, Issue.4
, pp. 396-400
-
-
Baker, M.E.1
-
33
-
-
34249994878
-
Functional aspects of 17betahydroxysteroid dehydrogenase 1 determined by comparison to a closely related retinol dehydrogenase
-
Mindnich, R.; Adamski, J. Functional aspects of 17betahydroxysteroid dehydrogenase 1 determined by comparison to a closely related retinol dehydrogenase. J Steroid Biochem Mol Biol, 2007, 104(3-5), 334-9.
-
(2007)
J Steroid Biochem Mol Biol
, vol.104
, Issue.3-5
, pp. 334-339
-
-
Mindnich, R.1
Adamski, J.2
-
34
-
-
77953083038
-
Molecular framework of steroid/retinoid discrimination in 17betahydroxysteroid dehydrogenase type 1 and photoreceptor-associated retinol dehydrogenase
-
Haller, F.; Moman, E.; Hartmann, R.W.; Adamski, J.; Mindnich, R. Molecular framework of steroid/retinoid discrimination in 17betahydroxysteroid dehydrogenase type 1 and photoreceptor-associated retinol dehydrogenase. J Mol Biol, 2010, 399(2), 255-67.
-
(2010)
J Mol Biol
, vol.399
, Issue.2
, pp. 255-267
-
-
Haller, F.1
Moman, E.2
Hartmann, R.W.3
Adamski, J.4
Mindnich, R.5
-
35
-
-
0027425436
-
Crystallization and preliminary X-ray diffraction analysis of the complex of human placental 17 beta-hydroxysteroid dehydrogenase with NADP+
-
Zhu, D.W.; Lee, X.; Breton, R.; Ghosh, D.; Pangborn, W.; Daux, W.L.; Lin, S.X. Crystallization and preliminary X-ray diffraction analysis of the complex of human placental 17 beta-hydroxysteroid dehydrogenase with NADP+. J Mol Biol, 1993, 234(1), 242-4.
-
(1993)
J Mol Biol
, vol.234
, Issue.1
, pp. 242-244
-
-
Zhu, D.W.1
Lee, X.2
Breton, R.3
Ghosh, D.4
Pangborn, W.5
Daux, W.L.6
Lin, S.X.7
-
36
-
-
0036615864
-
Purification, crystallization and preliminary X-ray diffraction results of human 17beta-hydroxysteroid dehydrogenase type 5
-
Zhou, M.; Qiu, W.; Chang, H.J.; Gangloff, A.; Lin, SX. Purification, crystallization and preliminary X-ray diffraction results of human 17beta-hydroxysteroid dehydrogenase type 5. Acta Crystallogr D Biol Crystallogr, 2002, 1048-50.
-
(2002)
Acta Crystallogr D Biol Crystallogr
, pp. 1048-1050
-
-
Zhou, M.1
Qiu, W.2
Chang, H.J.3
Gangloff, A.4
Lin, S.X.5
-
37
-
-
0041833725
-
Closing the gap: Identification of human 3-ketosteroid reductase, the last unknown enzyme of mammalian cholesterol biosynthesis
-
Marijanovic, Z.; Laubner, D.; Moller, G.; Gege, C.; Husen, B.; Adamski, J.; Breitling, R. Closing the gap: identification of human 3-ketosteroid reductase, the last unknown enzyme of mammalian cholesterol biosynthesis. Mol Endocrinol, 2003, 17(9), 1715-25.
-
(2003)
Mol Endocrinol
, vol.17
, Issue.9
, pp. 1715-1725
-
-
Marijanovic, Z.1
Laubner, D.2
Moller, G.3
Gege, C.4
Husen, B.5
Adamski, J.6
Breitling, R.7
-
38
-
-
40749094550
-
17beta-hydroxysteroid dehydrogenase Type 1, and not Type 12, is a target for endocrine therapy of hormone-dependent breast cancer
-
Day, J.M.; Foster, P.A.; Tutill, H.J.; Parsons, M.F.; Newman, S.P.; Chander, S.K.; Allan, G.M.; Lawrence, H.R.; Vicker, N.; Potter, B.V.; Reed, M.J.; Purohit, A. 17beta-hydroxysteroid dehydrogenase Type 1, and not Type 12, is a target for endocrine therapy of hormone-dependent breast cancer. Int J Cancer, 2008, 122, 1931-40.
-
(2008)
Int J Cancer
, vol.122
, pp. 1931-1940
-
-
Day, J.M.1
Foster, P.A.2
Tutill, H.J.3
Parsons, M.F.4
Newman, S.P.5
Chander, S.K.6
Allan, G.M.7
Lawrence, H.R.8
Vicker, N.9
Potter, B.V.10
Reed, M.J.11
Purohit, A.12
-
39
-
-
60549087132
-
Human HSD17B1 expression masculinizes transgenic female mice
-
Saloniemi, T.; Welsh, M.; Lamminen, T.; Saunders, P.; Mäkelä, S.; Streng, T.; Poutanen, M. Human HSD17B1 expression masculinizes transgenic female mice. Mol Cell Endocrinol, 2009, 301(1-2), 163-8.
-
(2009)
Mol Cell Endocrinol
, vol.301
, Issue.1-2
, pp. 163-168
-
-
Saloniemi, T.1
Welsh, M.2
Lamminen, T.3
Saunders, P.4
Mäkelä, S.5
Streng, T.6
Poutanen, M.7
-
40
-
-
40849113345
-
Placenta defects and embryonic lethality resulting from disruption of mouse hydroxysteroid (17-beta) dehydrogenase 2 gene
-
Rantakari, P.; Strauss, L.; Kiviranta, R.; Lagerbohm, H.; Paviala, J.; Holopainen, I.; Vainio, S.; Pakarinen, P.; Poutanen, M. Placenta defects and embryonic lethality resulting from disruption of mouse hydroxysteroid (17-beta) dehydrogenase 2 gene. Mol Endocrinol, 2008, 22(3), 665-75.
-
(2008)
Mol Endocrinol
, vol.22
, Issue.3
, pp. 665-675
-
-
Rantakari, P.1
Strauss, L.2
Kiviranta, R.3
Lagerbohm, H.4
Paviala, J.5
Holopainen, I.6
Vainio, S.7
Pakarinen, P.8
Poutanen, M.9
-
41
-
-
77950240539
-
Hydroxysteroid (17beta) dehydrogenase 7 activity is essential for fetal de novo cholesterol synthesis and for neuroectodermal survival and cardiovascular differentiation in early mouse embryos
-
Jokela, H.; Rantakari, P.; Lamminen, T.; Strauss, L.; Ola, R.; Mutka, A.L.; Gylling, H.; Miettinen, T.; Pakarinen, P.; Sainio, K.; Poutanen, M. Hydroxysteroid (17beta) dehydrogenase 7 activity is essential for fetal de novo cholesterol synthesis and for neuroectodermal survival and cardiovascular differentiation in early mouse embryos. Endocrinology, 2010, 151(4), 1884-92.
-
(2010)
Endocrinology
, vol.151
, Issue.4
, pp. 1884-1892
-
-
Jokela, H.1
Rantakari, P.2
Lamminen, T.3
Strauss, L.4
Ola, R.5
Mutka, A.L.6
Gylling, H.7
Miettinen, T.8
Pakarinen, P.9
Sainio, K.10
Poutanen, M.11
-
42
-
-
33644894458
-
Multifunctionality of human 17betahydroxysteroid dehydrogenases
-
Möller, G.; Adamski, J. Multifunctionality of human 17betahydroxysteroid dehydrogenases. Mol Cell Endocrinol, 2006, 248(1-2), 47-55.
-
(2006)
Mol Cell Endocrinol
, vol.248
, Issue.1-2
, pp. 47-55
-
-
Möller, G.1
Adamski, J.2
-
43
-
-
59049100782
-
The SDR (short-chain dehydrogenase/reductase and related enzymes) nomenclature initiative
-
Persson, B.; Kallberg, Y.; Bray, J.E.; Bruford, E.; Dellaporta, S.L.; Favia, A.D.; Duarte, R.G.; Jörnvall, H.; Kavanagh, K.L.; Kedishvili, N.; Kisiela, M.; Maser, E.; Mindnich, R.; Orchard, S.; Penning, T.M.; Thornton, J.M.; Adamski, J.; Oppermann, U. The SDR (short-chain dehydrogenase/reductase and related enzymes) nomenclature initiative. Chem Biol Interact, 2009, 178(1-3), 94-8.
-
(2009)
Chem Biol Interact
, vol.178
, Issue.1-3
, pp. 94-98
-
-
Persson, B.1
Kallberg, Y.2
Bray, J.E.3
Bruford, E.4
Dellaporta, S.L.5
Favia, A.D.6
Duarte, R.G.7
Jörnvall, H.8
Kavanagh, K.L.9
Kedishvili, N.10
Kisiela, M.11
Maser, E.12
Mindnich, R.13
Orchard, S.14
Penning, T.M.15
Thornton, J.M.16
Adamski, J.17
Oppermann, U.18
-
44
-
-
33847021147
-
Aldo-keto reductases and bioactivation/detoxication
-
Jin, Y.; Penning, T.M. Aldo-keto reductases and bioactivation/detoxication. Annu Rev Pharmacol Toxicol, 2007, 47, 263-92.
-
(2007)
Annu Rev Pharmacol Toxicol
, vol.47
, pp. 263-292
-
-
Jin, Y.1
Penning, T.M.2
-
45
-
-
0030925341
-
Molecular endocrinology of hydroxysteroid dehydrogenases
-
Penning, T.M. Molecular endocrinology of hydroxysteroid dehydrogenases. Endocr Rev, 1997, 18(3), 281-305.
-
(1997)
Endocr Rev
, vol.18
, Issue.3
, pp. 281-305
-
-
Penning, T.M.1
-
46
-
-
0033051603
-
Molecular determinants of steroid recognition and catalysis in aldo-keto reductases. Lessons from 3alpha-hydroxy steroid dehydrogenase
-
Penning, T.M. Molecular determinants of steroid recognition and catalysis in aldo-keto reductases. Lessons from 3alpha-hydroxy steroid dehydrogenase. J Steroid Biochem Mol Biol, 1999, 69(1-6), 211-25.
-
(1999)
J Steroid Biochem Mol Biol
, vol.69
, Issue.1-6
, pp. 211-225
-
-
Penning, T.M.1
-
47
-
-
0027959919
-
Site-directed mutagenesis of the putative active site of human 17 beta-hydroxysteroid dehydrogenase type 1
-
Puranen, T.J.; Poutanen, M.H.; Peltoketo, H.E.; Vihko, P.T.; Vihko, R.K. Site-directed mutagenesis of the putative active site of human 17 beta-hydroxysteroid dehydrogenase type 1. Biochem J, 1994, 304(Pt 1), 289-93.
-
(1994)
Biochem J
, vol.304
, Issue.1 Pt 1
, pp. 289-293
-
-
Puranen, T.J.1
Poutanen, M.H.2
Peltoketo, H.E.3
Vihko, P.T.4
Vihko, R.K.5
-
48
-
-
0029644733
-
Structure of human estrogenic 17 beta-hydroxysteroid dehydrogenase at 2.20 A resolution
-
Ghosh, D.; Pletnev, V.Z.; Zhu, D.W.; Wawrzak, Z.; Duax, W.L.; Pangborn, W.; Labrie, F.; Lin, S.X. Structure of human estrogenic 17 beta-hydroxysteroid dehydrogenase at 2.20 A resolution. Structure, 1995, 3(5), 503-13.
-
(1995)
Structure
, vol.3
, Issue.5
, pp. 503-513
-
-
Ghosh, D.1
Pletnev, V.Z.2
Zhu, D.W.3
Wawrzak, Z.4
Duax, W.L.5
Pangborn, W.6
Labrie, F.7
Lin, S.X.8
-
49
-
-
13644269467
-
Mechanistic roles of Ser-114, Tyr-155, and Lys-159 in alphahydroxysteroid dehydrogenase/carbonyl reductase from Comamonas testosteroni
-
Hwang, C.C.; Chang, Y.H.; Hsu, C.N.; Hsu, H.H.; Li, C.W.; Pon. HI. Mechanistic roles of Ser-114, Tyr-155, and Lys-159 in alphahydroxysteroid dehydrogenase/carbonyl reductase from Comamonas testosteroni. J Biol Chem, 2005, 280(5), 3522-8.
-
(2005)
J Biol Chem
, vol.280
, Issue.5
, pp. 3522-3528
-
-
Hwang, C.C.1
Chang, Y.H.2
Hsu, C.N.3
Hsu, H.H.4
Li, C.W.5
Pon, H.I.6
-
50
-
-
0037067783
-
Critical residues for structure and catalysis in short-chain dehydrogenases/reductases
-
Filling, C.; Berndt, K.D.; Benach, J.; Knapp, S.; Prozorovski, T.; Nordling, E.; Ladenstein, R.; Jörnvall, H.; Oppermann, U. Critical residues for structure and catalysis in short-chain dehydrogenases/reductases. J Biol Chem, 2002, 277(28), 25677-84.
-
(2002)
J Biol Chem
, vol.277
, Issue.28
, pp. 25677-25684
-
-
Filling, C.1
Berndt, K.D.2
Benach, J.3
Knapp, S.4
Prozorovski, T.5
Nordling, E.6
Ladenstein, R.7
Jörnvall, H.8
Oppermann, U.9
-
51
-
-
13144277564
-
Peroxisomal D-hydroxyacyl-CoA dehydrogenase deficiency: Resolution of the enzyme defect and its molecular basis in bifunctional protein deficiency
-
van Grunsven, E.G.; van Berkel, E.; Ijlst, L.; Vreken, P.; de Klerk, J.B.; Adamski, J.; Lemonde, H.; Clayton, P.T.; Cuebas, D.A.; Wanders, R.J. Peroxisomal D-hydroxyacyl-CoA dehydrogenase deficiency: resolution of the enzyme defect and its molecular basis in bifunctional protein deficiency. Proc Natl Acad Sci U S A, 1998, 95(5), 2128-33.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, Issue.5
, pp. 2128-2133
-
-
van Grunsven, E.G.1
van Berkel, E.2
Ijlst, L.3
Vreken, P.4
de Klerk, J.B.5
Adamski, J.6
Lemonde, H.7
Clayton, P.T.8
Cuebas, D.A.9
Wanders, R.J.10
-
52
-
-
62949206264
-
17Beta-hydroxysteroid dehydrogenase enzymes and breast cancer
-
Jansson, A. 17Beta-hydroxysteroid dehydrogenase enzymes and breast cancer. J Steroid Biochem Mol Biol, 2009, 114(1-2), 64-7.
-
(2009)
J Steroid Biochem Mol Biol
, vol.114
, Issue.1-2
, pp. 64-67
-
-
Jansson, A.1
-
53
-
-
79957731848
-
Identification of chemically diverse, novel inhibitors of 17hydroxysteroid dehydrogenase type 3 and 5 by pharmacophore-based virtual screening
-
Schuster, D.; Kowalik, D.; Kirchmair, J.; Laggner, C.; Markt, P.; Aebischer-Gumy, C.; Ströhle, F.; Möller, G.; Wolber, G.; Wilckens, T.; Langer, T.; Odermatt, A.; Adamski, J. Identification of chemically diverse, novel inhibitors of 17hydroxysteroid dehydrogenase type 3 and 5 by pharmacophore-based virtual screening. J Steroid Biochem Mol Biol, 2011, 125(1-2), 148-61.
-
(2011)
J Steroid Biochem Mol Biol
, vol.125
, Issue.1-2
, pp. 148-161
-
-
Schuster, D.1
Kowalik, D.2
Kirchmair, J.3
Laggner, C.4
Markt, P.5
Aebischer-Gumy, C.6
Ströhle, F.7
Möller, G.8
Wolber, G.9
Wilckens, T.10
Langer, T.11
Odermatt, A.12
Adamski, J.13
-
54
-
-
77749245862
-
Novel hydroxysteroid (17beta) dehydrogenase 1 inhibitors reverse estrogen-induced endometrial hyperplasia in transgenic mice
-
Saloniemi, T.; Järvensivu, P.; Koskimies, P.; Jokela, H.; Lamminen, T.; Ghaem-Maghami, S.; Dina, R.; Damdimopoulou, P.; Mäkelä, S.; Perheentupa, A.; Kujari, H.; Brosens, J.; Poutanen, M. Novel hydroxysteroid (17beta) dehydrogenase 1 inhibitors reverse estrogen-induced endometrial hyperplasia in transgenic mice. Am J Pathol, 2010, 176(3), 1443-51.
-
(2010)
Am J Pathol
, vol.176
, Issue.3
, pp. 1443-1451
-
-
Saloniemi, T.1
Järvensivu, P.2
Koskimies, P.3
Jokela, H.4
Lamminen, T.5
Ghaem-Maghami, S.6
Dina, R.7
Damdimopoulou, P.8
Mäkelä, S.9
Perheentupa, A.10
Kujari, H.11
Brosens, J.12
Poutanen, M.13
-
55
-
-
77957695010
-
17ß-hydroxysteroid dehydrogenase inhibitors
-
Day, J.M.; Tutill, H.J.; Purohit, A. 17ß-hydroxysteroid dehydrogenase inhibitors. Minerva Endocrinol, 2010, 35(2), 87-108.
-
(2010)
Minerva Endocrinol
, vol.35
, Issue.2
, pp. 87-108
-
-
Day, J.M.1
Tutill, H.J.2
Purohit, A.3
-
56
-
-
70349150178
-
Advances in development of inhibitors of 17beta hydroxysteroid dehydrogenases
-
Poirier, D. Advances in development of inhibitors of 17beta hydroxysteroid dehydrogenases. Anticancer Agents Med Chem, 2009, 9(6), 642-60.
-
(2009)
Anticancer Agents Med Chem
, vol.9
, Issue.6
, pp. 642-660
-
-
Poirier, D.1
-
57
-
-
77955836270
-
17beta-Hydroxysteroid dehydrogenase inhibitors: A patent review
-
Poirier, D. 17beta-Hydroxysteroid dehydrogenase inhibitors: a patent review. Expert Opin Ther Pat, 2010, 20(9), 1123-45.
-
(2010)
Expert Opin Ther Pat
, vol.20
, Issue.9
, pp. 1123-1145
-
-
Poirier, D.1
-
58
-
-
77956199036
-
Species used for drug testing reveal different inhibition susceptibility for 17betahydroxysteroid dehydrogenase type 1
-
] Möller, G.; Husen, B.; Kowalik, D.; Hirvelä, L.; Plewczynski, D.; Rychlewski, L.; Messinger, J.; Thole, H.; Adamski, J. Species used for drug testing reveal different inhibition susceptibility for 17betahydroxysteroid dehydrogenase type 1. PLoS One, 2010, 5(6), e10969.
-
(2010)
PLoS One
, vol.5
, Issue.6
-
-
Möller, G.1
Husen, B.2
Kowalik, D.3
Hirvelä, L.4
Plewczynski, D.5
Rychlewski, L.6
Messinger, J.7
Thole, H.8
Adamski, J.9
-
59
-
-
60249101573
-
Zebrafish 17beta-hydroxysteroid dehydrogenases: An evolutionary perspective
-
Mindnich, R.; Adamski, J. Zebrafish 17beta-hydroxysteroid dehydrogenases: an evolutionary perspective. Mol Cell Endocrinol, 2009, 301(1-2), 20-6.
-
(2009)
Mol Cell Endocrinol
, vol.301
, Issue.1-2
, pp. 20-26
-
-
Mindnich, R.1
Adamski, J.2
-
60
-
-
0026737624
-
Subunit identity of the dimeric 17 beta-hydroxysteroid dehydrogenase from human placenta
-
Lin, S.X.; Yang, F.; Jin, J.Z.; Breton, R.; Zhu, D.W.; Luu-The, V.; Labrie, F. Subunit identity of the dimeric 17 beta-hydroxysteroid dehydrogenase from human placenta. J Biol Chem, 1992, 267(23), 16182-7.
-
(1992)
J Biol Chem
, vol.267
, Issue.23
, pp. 16182-16187
-
-
Lin, S.X.1
Yang, F.2
Jin, J.Z.3
Breton, R.4
Zhu, D.W.5
Luu-The, V.6
Labrie, F.7
-
61
-
-
0033532388
-
Human estrogenic 17beta-hydroxysteroid dehydrogenase: Predominance of estrone reduction and its induction by NADPH
-
Jin, J.Z.; Lin, S.X. Human estrogenic 17beta-hydroxysteroid dehydrogenase: predominance of estrone reduction and its induction by NADPH. Biochem Biophys Res Commun, 1999, 259(2), 489-93.
-
(1999)
Biochem Biophys Res Commun
, vol.259
, Issue.2
, pp. 489-493
-
-
Jin, J.Z.1
Lin, S.X.2
-
62
-
-
0037317465
-
Pseudo-symmetry of C19 steroids, alternative binding orientations, and multispecificity in human estrogenic 17beta-hydroxysteroid dehydrogenase
-
Gangloff, A.; Shi, R.; Nahoum, V.; Lin, SX. Pseudo-symmetry of C19 steroids, alternative binding orientations, and multispecificity in human estrogenic 17beta-hydroxysteroid dehydrogenase. FASEB J, 2003, 17(2), 274-6.
-
(2003)
FASEB J
, vol.17
, Issue.2
, pp. 274-276
-
-
Gangloff, A.1
Shi, R.2
Nahoum, V.3
Lin, S.X.4
-
63
-
-
0038604345
-
How estrogenspecific proteins discriminate estrogens from androgens: A common steroid binding site architecture
-
Nahoum, V.; Gangloff, A.; Shi, R.; Lin, S.X. How estrogenspecific proteins discriminate estrogens from androgens: a common steroid binding site architecture. FASEB J, 2003, 17(10), 1334-6.
-
(2003)
FASEB J
, vol.17
, Issue.10
, pp. 1334-1336
-
-
Nahoum, V.1
Gangloff, A.2
Shi, R.3
Lin, S.X.4
-
64
-
-
77950421854
-
17beta-hydroxysteroid dehydrogenase type 1 stimulates breast cancer by dihydrotestosterone inactivation in addition to estradiol production
-
Aka, J.A.; Mazumdar, M.; Chen, C.Q.; Poirier, D.; Lin, SX. 17beta-hydroxysteroid dehydrogenase type 1 stimulates breast cancer by dihydrotestosterone inactivation in addition to estradiol production. Mol Endocrinol, 2010, 24(4), 832-45.
-
(2010)
Mol Endocrinol
, vol.24
, Issue.4
, pp. 832-845
-
-
Aka, J.A.1
Mazumdar, M.2
Chen, C.Q.3
Poirier, D.4
Lin, S.X.5
-
65
-
-
84861993200
-
17betahydroxysteroid dehydrogenase type 1 modulates breast cancer protein profile and impacts cell migration
-
Aka, J.A.; Zerradi, M.; Houle, F.; Huot, J.; Lin, S.X. 17betahydroxysteroid dehydrogenase type 1 modulates breast cancer protein profile and impacts cell migration. Breast Cancer Res, 2012, 14(3), R92.
-
(2012)
Breast Cancer Res
, vol.14
, Issue.3
-
-
Aka, J.A.1
Zerradi, M.2
Houle, F.3
Huot, J.4
Lin, S.X.5
-
66
-
-
3042829462
-
Crystal structures of the multispecific 17beta-hydroxysteroid dehydrogenase type 5: Critical androgen regulation in human peripheral tissues
-
Qiu, W.; Zhou, M.; Labrie, F.; Lin, S.X. Crystal structures of the multispecific 17beta-hydroxysteroid dehydrogenase type 5: critical androgen regulation in human peripheral tissues. Mol Endocrinol, 2004, 18(7), 1798-807.
-
(2004)
Mol Endocrinol
, vol.18
, Issue.7
, pp. 1798-1807
-
-
Qiu, W.1
Zhou, M.2
Labrie, F.3
Lin, S.X.4
-
67
-
-
79957722662
-
Inhibitors of type 5 17 hydroxysteroid dehydrogenase (AKR1C3): Overview and structural insights
-
Byrns, M.C.; Jin, Y.; Penning, T.M. Inhibitors of type 5 17 hydroxysteroid dehydrogenase (AKR1C3): overview and structural insights. J Steroid Biochem Mol Biol, 2011, 125(1-2), 95-104.
-
(2011)
J Steroid Biochem Mol Biol
, vol.125
, Issue.1-2
, pp. 95-104
-
-
Byrns, M.C.1
Jin, Y.2
Penning, T.M.3
-
68
-
-
33644973274
-
Structural basis of the multispecificity demonstrated by 17beta-hydroxysteroid dehydrogenase types 1 and 5
-
Lin, S.X.; Shi, R.; Qiu, W.; Azzi, A.; Zhu, D.W.; Dabbagh, H.A.; Zhou, M. Structural basis of the multispecificity demonstrated by 17beta-hydroxysteroid dehydrogenase types 1 and 5. Mol Cell Endocrinol, 2006, 248(1-2), 38-46.
-
(2006)
Mol Cell Endocrinol
, vol.248
, Issue.1-2
, pp. 38-46
-
-
Lin, S.X.1
Shi, R.2
Qiu, W.3
Azzi, A.4
Zhu, D.W.5
Dabbagh, H.A.6
Zhou, M.7
-
69
-
-
34247218025
-
Structure-based inhibitor design for an enzyme that binds different steroids: A potent inhibitor for human type 5 17beta-hydroxysteroid dehydrogenase
-
Qiu, W.; Zhou, M.; Mazumdar, M.; Azzi, A.; Ghanmi, D.; LuuThe, V.; Labrie, F.; Lin, S.X. Structure-based inhibitor design for an enzyme that binds different steroids: a potent inhibitor for human type 5 17beta-hydroxysteroid dehydrogenase. J Biol Chem, 2007, 282(11), 8368-79.
-
(2007)
J Biol Chem
, vol.282
, Issue.11
, pp. 8368-8379
-
-
Qiu, W.1
Zhou, M.2
Mazumdar, M.3
Azzi, A.4
Ghanmi, D.5
Luuthe, V.6
Labrie, F.7
Lin, S.X.8
-
70
-
-
60249089307
-
Reductive 17betahydroxysteroid dehydrogenases in the sulfatase pathway: Critical in the cell proliferation of breast cancer
-
Aka, J.A.; Mazumdar, M.; Lin, S.X. Reductive 17betahydroxysteroid dehydrogenases in the sulfatase pathway: critical in the cell proliferation of breast cancer. Mol Cell Endocrinol, 2009, 301(1-2), 183-90.
-
(2009)
Mol Cell Endocrinol
, vol.301
, Issue.1-2
, pp. 183-190
-
-
Aka, J.A.1
Mazumdar, M.2
Lin, S.X.3
-
71
-
-
0029998812
-
17hydroxysteroid dehydrogenase: Inhibitors and inhibitors design. Endocr
-
Penning, T.M. 17hydroxysteroid dehydrogenase: inhibitors and inhibitors design. Endocr. Relat Cancer, 1996, 3, 41-56.
-
(1996)
Relat Cancer
, vol.3
, pp. 41-56
-
-
Penning, T.M.1
-
72
-
-
0037277521
-
Inhibitors of 17 beta-hydroxysteroid dehydrogenases
-
Poirier, D. Inhibitors of 17 beta-hydroxysteroid dehydrogenases. Curr Med Chem, 2003, 10(6), 453-77.
-
(2003)
Curr Med Chem
, vol.10
, Issue.6
, pp. 453-477
-
-
Poirier, D.1
-
73
-
-
39049103081
-
Inhibitors of 17betahydroxysteroid dehydrogenase type 1
-
Brozic, P.; Lanisnik Risner, T.; Gobec, S. Inhibitors of 17betahydroxysteroid dehydrogenase type 1. Curr Med Chem, 2008, 15(2), 137-50.
-
(2008)
Curr Med Chem
, vol.15
, Issue.2
, pp. 137-150
-
-
Brozic, P.1
Lanisnik, R.T.2
Gobec, S.3
-
74
-
-
79957737745
-
Contribution to the development of inhibitors of 17 hydroxysteroid dehydrogenase types 1 and 7: Key tools for studying and treating estrogen-dependent diseases
-
Poirier, D. Contribution to the development of inhibitors of 17 hydroxysteroid dehydrogenase types 1 and 7: key tools for studying and treating estrogen-dependent diseases. J Steroid Biochem Mol Biol, 2011, 125(1-2), 83-94.
-
(2011)
J Steroid Biochem Mol Biol
, vol.125
, Issue.1-2
, pp. 83-94
-
-
Poirier, D.1
-
75
-
-
53849119147
-
Design and validation of specific inhibitors of 17beta-hydroxysteroid dehydrogenases for therapeutic application in breast and prostate cancer, and in endometriosis
-
Day, J.M.; Tutill, H.J.; Purohit, A.; Reed, M.J. Design and validation of specific inhibitors of 17beta-hydroxysteroid dehydrogenases for therapeutic application in breast and prostate cancer, and in endometriosis. Endocr Relat Cancer, 2008, 15(3), 665-92.
-
(2008)
Endocr Relat Cancer
, vol.15
, Issue.3
, pp. 665-692
-
-
Day, J.M.1
Tutill, H.J.2
Purohit, A.3
Reed, M.J.4
-
76
-
-
57749106633
-
New cancer drugs targeting the biosynthesis of estrogens and androgens
-
Poirier, D. New cancer drugs targeting the biosynthesis of estrogens and androgens, Drug Devel Res, 2008, 69, 304-318
-
(2008)
Drug Devel Res
, vol.69
, pp. 304-318
-
-
Poirier, D.1
-
77
-
-
0034749467
-
Critical residues for the specificity of cofactors and substrates in human estrogenic 17beta-hydroxysteroid dehydrogenase 1: Variants designed from the three-dimensional structure of the enzyme
-
Huang, Y.W.; Pineau, I.; Chang, H.J.; Azzi, A.; Bellemare, V.; Laberge, S.; Lin, S.X. Critical residues for the specificity of cofactors and substrates in human estrogenic 17beta-hydroxysteroid dehydrogenase 1: variants designed from the three-dimensional structure of the enzyme. Mol Endocrinol, 2001, 15(11), 2010-20.
-
(2001)
Mol Endocrinol
, vol.15
, Issue.11
, pp. 2010-2020
-
-
Huang, Y.W.1
Pineau, I.2
Chang, H.J.3
Azzi, A.4
Bellemare, V.5
Laberge, S.6
Lin, S.X.7
-
78
-
-
60249092334
-
Structureactivity study in the class of 6-(3'-hydroxyphenyl)naphthalenes leading to an optimization of a pharmacophore model for 17betahydroxysteroid dehydrogenase type 1 (17beta-HSD1) inhibitors
-
Marchais-Oberwinkler, S.; Frotscher, M.; Ziegler, E.; Werth, R.; Kruchten, P.; Messinger, J.; Thole, H.; Hartmann, R.W. Structureactivity study in the class of 6-(3'-hydroxyphenyl)naphthalenes leading to an optimization of a pharmacophore model for 17betahydroxysteroid dehydrogenase type 1 (17beta-HSD1) inhibitors. Mol Cell Endocrinol, 2009, 301(1-2), 205-11.
-
(2009)
Mol Cell Endocrinol
, vol.301
, Issue.1-2
, pp. 205-211
-
-
Marchais-Oberwinkler, S.1
Frotscher, M.2
Ziegler, E.3
Werth, R.4
Kruchten, P.5
Messinger, J.6
Thole, H.7
Hartmann, R.W.8
-
79
-
-
33644899920
-
New inhibitors of 17beta-hydroxysteroid dehydrogenase type 1
-
Messinger, J.; Hirvelä, L.; Husen, B.; Kangas, L.; Koskimies, P.; Pentikäinen, O.; Saarenketo, P.; Thole, H. New inhibitors of 17beta-hydroxysteroid dehydrogenase type 1. Mol Cell Endocrinol, 2006, 248(1-2), 192-8.
-
(2006)
Mol Cell Endocrinol
, vol.248
, Issue.1-2
, pp. 192-198
-
-
Messinger, J.1
Hirvelä, L.2
Husen, B.3
Kangas, L.4
Koskimies, P.5
Pentikäinen, O.6
Saarenketo, P.7
Thole, H.8
-
80
-
-
60249090183
-
Relative involvement of three 17beta-hydroxysteroid dehydrogenases (types 1, 7 and 12) in the formation of estradiol in various breast cancer cell lines using selective inhibitors
-
Laplante, Y.; Rancourt, C.; Poirier, D. Relative involvement of three 17beta-hydroxysteroid dehydrogenases (types 1, 7 and 12) in the formation of estradiol in various breast cancer cell lines using selective inhibitors. Mol Cell Endocrinol, 2009, 301(1-2), 146-53.
-
(2009)
Mol Cell Endocrinol
, vol.301
, Issue.1-2
, pp. 146-153
-
-
Laplante, Y.1
Rancourt, C.2
Poirier, D.3
-
81
-
-
33644900197
-
Evaluation of inhibitors for 17beta-hydroxysteroid dehydrogenase type 1 in vivo in immunodeficient mice inoculated with MCF-7 cells stably expressing the recombinant human enzyme
-
] Husen, B.; Huhtinen, K.; Poutanen, M.; Kangas, L.; Messinger, J.; Thole, H. Evaluation of inhibitors for 17beta-hydroxysteroid dehydrogenase type 1 in vivo in immunodeficient mice inoculated with MCF-7 cells stably expressing the recombinant human enzyme. Mol Cell Endocrinol, 2006, 248(1-2), 109-13.
-
(2006)
Mol Cell Endocrinol
, vol.248
, Issue.1-2
, pp. 109-113
-
-
Husen, B.1
Huhtinen, K.2
Poutanen, M.3
Kangas, L.4
Messinger, J.5
Thole, H.6
-
82
-
-
33751240474
-
Human hydroxysteroid (17-beta) dehydrogenase 1 expression enhances estrogen sensitivity of MCF-7 breast cancer cell xenografts
-
Husen, B.; Huhtinen, K.; Saloniemi, T.; Messinger, J.; Thole, H.H.; Poutanen, M. Human hydroxysteroid (17-beta) dehydrogenase 1 expression enhances estrogen sensitivity of MCF-7 breast cancer cell xenografts. Endocrinology, 2006,147(11), 5333-9.
-
(2006)
Endocrinology
, vol.147
, Issue.11
, pp. 5333-5339
-
-
Husen, B.1
Huhtinen, K.2
Saloniemi, T.3
Messinger, J.4
Thole, H.H.5
Poutanen, M.6
-
83
-
-
17444417513
-
Novel and potent 17beta-hydroxysteroid dehydrogenase type 1 inhibitors
-
Lawrence, H.R.; Vicker, N.; Allan, G.M.; Smith, A.; Mahon, M.F.; Tutill, H, J.; Purohit, A.; Reed, M. J.; Potter, B. V. Novel and potent 17beta-hydroxysteroid dehydrogenase type 1 inhibitors. J Med Chem, 2005, 48(8), 2759-62.
-
(2005)
J Med Chem
, vol.48
, Issue.8
, pp. 2759-2762
-
-
Lawrence, H.R.1
Vicker, N.2
Allan, G.M.3
Smith, A.4
Mahon, M.F.5
Tutill, H.6
-
84
-
-
80052629623
-
Crucial Role of 3-bromoethyl in removing the estrogenic activity of 17HSD1 inhibitor 16 (mcarbamoylbenzyl)estradiol
-
Maltais, R.; Ayan, D.; Poirier, D. Crucial Role of 3-bromoethyl in removing the estrogenic activity of 17HSD1 inhibitor 16 (mcarbamoylbenzyl)estradiol. ACS Med Chem Lett, 2011, 2(9),678-681.
-
(2011)
ACS Med Chem Lett
, vol.2
, Issue.9
, pp. 678-681
-
-
Maltais, R.1
Ayan, D.2
Poirier, D.3
-
85
-
-
84867422422
-
A new nonestrogenic steroidal inhibitor of 17hydroxysteroid dehydrogenase type I blocks the estrogen-dependent breast cancer tumor growth induced by estrone
-
Ayan, D.; Maltais, R.; Roy, J.; Poirier, D. A new nonestrogenic steroidal inhibitor of 17hydroxysteroid dehydrogenase type I blocks the estrogen-dependent breast cancer tumor growth induced by estrone. Mol Cancer Ther, 2012, 11(10), 2096-104.
-
(2012)
Mol Cancer Ther
, vol.11
, Issue.10
, pp. 2096-2104
-
-
Ayan, D.1
Maltais, R.2
Roy, J.3
Poirier, D.4
-
86
-
-
0014512087
-
A soluble 17beta-hydroxysteroid dehydrognease from human placenta. The binding of pyrimidine nucleotides and steroids
-
Jarabak, J.; Sack GH, Jr. A soluble 17beta-hydroxysteroid dehydrognease from human placenta. The binding of pyrimidine nucleotides and steroids. Biochemistry, 1969, 8(5), 2203-12.
-
(1969)
Biochemistry
, vol.8
, Issue.5
, pp. 2203-2212
-
-
Jarabak, J.1
Sack Jr., G.H.2
-
87
-
-
77955923386
-
Molecular therapy of breast cancer: Extensive endocrine research and clinic trials for decades
-
Lin, S.X.; Chen, J.; Mazumdar, M.; Poirier, D.; Wang, C.; Azzi, A.; Zhou, M. Molecular therapy of breast cancer: extensive endocrine research and clinic trials for decades. Nat Rev Endocrinol, 2010, 6(9), 485-93.
-
(2010)
Nat Rev Endocrinol
, vol.6
, Issue.9
, pp. 485-493
-
-
Lin, S.X.1
Chen, J.2
Mazumdar, M.3
Poirier, D.4
Wang, C.5
Azzi, A.6
Zhou, M.7
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