Binding mechanism of coronavirus main proteinase with ligands and its implication to drug design against SARS

Biochemical and Biophysical Research Communications

Volumn 308, Issue 1, 2003, Pages 148-151

  Chou, Kuo Chen ^a,b   Wei, Dong Qing ^b   Zhong, Wei Zhu ^a,b  

^a Gordon Life Science Institute   (United States)

^b TIANJIN NORMAL UNIVERSITY   (China)

Author keywords

"Distorted key" mechanism; AG7088; Binding pocket; Coronavirus proteinase; KZ7088; Octapeptide substrate; SARS

Indexed keywords

ANTIVIRUS AGENT; KZ 7088; OCTAPEPTIDE; PROTEINASE; RUPINTRIVIR; UNCLASSIFIED DRUG; VIRUS PROTEIN;

ARTICLE; CORONAVIRUS; DRUG BINDING; DRUG DESIGN; DRUG RESEARCH; HYDROGEN BOND; MUTAGENESIS; PRIORITY JOURNAL; PROTEIN BINDING; SEVERE ACUTE RESPIRATORY SYNDROME; VIRUS PNEUMONIA;

CORONAVIRUS; SARS CORONAVIRUS;

EID: 0041848237     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-291X(03)01342-1     Document Type: Article

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