Functional aspects of 17beta-hydroxysteroid dehydrogenase 1 determined by comparison to a closely related retinol dehydrogenase

Journal of Steroid Biochemistry and Molecular Biology

Volumn 104, Issue 3-5, 2007, Pages 334-339

  Mindnich, R ^a   Adamski, J ^a  

^a INSTITUTE OF EPIDEMIOLOGY   (Germany)

Author keywords

17Beta hydroxysteroid dehydrogenase; Evolution; Retinol dehydrogenase; Zebrafish

Indexed keywords

17BETA HYDROXYSTEROID DEHYDROGENASE 1; ANDROSTENEDIONE; ESTRADIOL; ESTRONE; RETINOL DEHYDROGENASE; TESTOSTERONE; TESTOSTERONE 17BETA DEHYDROGENASE; UNCLASSIFIED DRUG;

ARTICLE; CELL STRAIN HEK293; CLONING; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME SPECIFICITY; ENZYMOLOGY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; MUTANT; SEQUENCE ANALYSIS; STEROID METABOLISM; STRUCTURE ACTIVITY RELATION; WILD TYPE; ZEBRA FISH;

17-HYDROXYSTEROID DEHYDROGENASES; ALCOHOL OXIDOREDUCTASES; AMINO ACID SEQUENCE; ANIMALS; CELLS, CULTURED; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN STRUCTURE, TERTIARY; RETINOIDS; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID; STEROIDS; SUBSTRATE SPECIFICITY; TRANSFECTION; ZEBRAFISH;

DANIO RERIO;

EID: 34249994878     PISSN: 09600760     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jsbmb.2007.03.013     Document Type: Article

References (36)

1. Talalay P., Dobson M.M., and Tapley D.F. Oxidative degradation of testosterone by adaptive enzymes. Nature 170 4328 (1952) 620-621
2. Luu-The V. Analysis and characteristics of multiple types of human 17beta-hydroxysteroid dehydrogenase. J. Steroid Biochem. Mol. Biol. 76 1-5 (2001) 143-151
3. V. Luu-The, P. Tremblay, F. Labrie, Characterization of type 12 17{beta}-hydroxysteroid dehydrogenase (17{beta}-HSD12), an isoform of type 3 17{beta}-hydroxysteroid dehydrogenase responsible for estradiol formation in women, Mol. Endocrinol. (2005).
4. Mindnich R., Moller G., and Adamski J. The role of 17 beta-hydroxysteroid dehydrogenases. Mol. Cell. Endocrinol. 218 1/2 (2004) 7-20
5. Moeller G., and Adamski J. Multifunctionality of human 17beta-hydroxysteroid dehydrogenases. Mol. Cell. Endocrinol. 248 1/2 (2006) 47-55
6. Kazeto Y., Ijiri S., Matsubara H., Adachi S., and Yamauchi K. Cloning of 17beta-hydroxysteroid dehydrogenase-I cDNAs from Japanese eel ovary. Biochem. Biophys. Res. Commun. 279 2 (2000) 451-456
7. Wajima Y., Furusawa T., Kawauchi S., Wakabayashi N., Nakabayashi O., Nishimori K., and Mizuno S. The cDNA cloning and transient expression of an ovary-specific 17beta-hydroxysteroid dehydrogenase of chickens. Gene 233 1/2 (1999) 75-82
8. Mindnich R., Deluca D., and Adamski J. Identification and characterization of 17 beta-hydroxysteroid dehydrogenases in the zebrafish, Danio rerio. Mol. Cell. Endocrinol. 215 1/2 (2004) 19-30
9. Nokelainen P., Puranen T., Peltoketo H., Orava M., Vihko P., and Vihko R. Molecular cloning of mouse 17 beta-hydroxysteroid dehydrogenase type 1 and characterization of enzyme activity. Eur. J. Biochem. 236 2 (1996) 482-490
10. Puranen T., Poutanen M., Ghosh D., Vihko R., and Vihko P. Origin of substrate specificity of human and rat 17beta-hydroxysteroid dehydrogenase type 1, using chimeric enzymes and site-directed substitutions. Endocrinology 138 8 (1997) 3532-3539
11. Zhou L.Y., Wang D.S., Senthilkumaran B., Yoshikuni M., Shibata Y., Kobayashi T., Sudhakumari C.C., and Nagahama Y. Cloning, expression and characterization of three types of 17beta-hydroxysteroid dehydrogenases from the Nile tilapia, Oreochromis niloticus. J. Mol. Endocrinol. 35 1 (2005) 103-116
12. Dumont M., Luu-The V., de Launoit Y., and Labrie F. Expression of human 17beta-hydroxysteroid dehydrogenase in mammalian cells. J. Steroid Biochem. Mol. Biol. 41 3-8 (1992) 605-608
13. Strickler R.C., and Tobias B. Estradiol 17beta-dehydrogenase and 20alpha-hydroxysteroid dehydrogenase from human placental cytosol: one enzyme with two activities?. Steroids 36 2 (1980) 243-253
14. Thomas J.L., and Strickler R.C. Human placental 17beta-estradiol dehydrogenase and 20alpha-hydroxysteroid dehydrogenase. Studies with 6beta-bromoacetoxyprogesterone. J. Biol. Chem. 258 3 (1983) 1587-1590
15. Puranen T., Poutanen M., Ghosh D., Vihko P., and Vihko R. Characterization of structural and functional properties of human 17 beta-hydroxysteroid dehydrogenase type 1 using recombinant enzymes and site-directed mutagenesis. Mol. Endocrinol. 11 1 (1997) 77-86
16. Rattner A., Smallwood P.M., and Nathans J. Identification and characterization of all-trans-retinol dehydrogenase from photoreceptor outer segments, the visual cycle enzyme that reduces all-trans-retinal to all-trans-retinol. J. Biol. Chem. 275 15 (2000) 11034-11043
17. Guex N., and Peitsch M.C. SWISS-MODEL and the Swiss-PdbViewer: an environment for comparative protein modeling. Electrophoresis 18 15 (1997) 2714-2723
18. Schwede T., Diemand A., Guex N., and Peitsch M.C. Protein structure computing in the genomic era. Res. Microbiol. 151 2 (2000) 107-112
19. Stocker U., and van Gunsteren W.F. Molecular dynamics simulation of hen egg white lysozyme: a test of the GROMOS96 force field against nuclear magnetic resonance data. Proteins 40 1 (2000) 145-153
20. Mazza C., Breton R., Housset D., and Fontecilla-Camps J.C. Unusual charge stabilization of NADP+ in 17beta-hydroxysteroid dehydrogenase. J. Biol. Chem. 273 14 (1998) 8145-8152
21. Breton R., Housset D., Mazza C., and Fontecilla-Camps J.C. The structure of a complex of human 17beta-hydroxysteroid dehydrogenase with estradiol and NADP+ identifies two principal targets for the design of inhibitors. Structure 4 8 (1996) 905-915
22. Pontius J., Richelle J., and Wodak S.J. Deviations from standard atomic volumes as a quality measure for protein crystal structures. J. Mol. Biol. 264 1 (1996) 121-136
23. Hooft R.W., Vriend G., Sander C., and Abola E.E. Errors in protein structures. Nature 381 6580 (1996) 272
24. Mindnich R., Haller F., Halbach F., Moeller G., Hrabe de Angelis M., and Adamski J. Androgen metabolism via 17beta-hydroxysteroid dehydrogenase type 3 in mammalian and non-mammalian vertebrates: comparison of the human and the zebrafish enzyme. J. Mol. Endocrinol. 35 2 (2005) 305-316
25. Peltoketo H., Luu-The V., Simard J., and Adamski J. 17Beta-hydroxysteroid dehydrogenase (HSD)/17-ketosteroid reductase (KSR) family; nomenclature and main characteristics of the 17HSD/KSR enzymes. J. Mol. Endocrinol. 23 1 (1999) 1-11
26. Ong O.C., Ota I.M., Clarke S., and Fung B.K. The membrane binding domain of rod cGMP phosphodiesterase is posttranslationally modified by methyl esterification at a C-terminal cysteine. Proc. Natl. Acad. Sci. U.S.A. 86 23 (1989) 9238-9242
27. Willumsen B.M., Norris K., Papageorge A.G., Hubbert N.L., and Lowy D.R. Harvey murine sarcoma virus p21 ras protein: biological and biochemical significance of the cysteine nearest the carboxy terminus. EMBO J. 3 11 (1984) 2581-2585
28. Hancock J.F., Magee A.I., Childs J.E., and Marshall C.J. All ras proteins are polyisoprenylated but only some are palmitoylated. Cell 57 7 (1989) 1167-1177
29. Ghosh D., Pletnev V.Z., Zhu D.W., Wawrzak Z., Duax W.L., Pangborn W., Labrie F., and Lin S.X. Structure of human estrogenic 17beta-hydroxysteroid dehydrogenase at 2.20 A resolution. Structure 3 5 (1995) 503-513
30. Setiawan V.W., Hankinson S.E., Colditz G.A., Hunter D.J., and De Vivo I. HSD17B1 gene polymorphisms and risk of endometrial and breast cancer. Cancer Epidemiol. Biomar. Prev. 13 2 (2004) 213-219
31. Tsuchiya M., Nakao H., Katoh T., Sasaki H., Hiroshima M., Tanaka T., Matsunaga T., Hanaoka T., Tsugane S., and Ikenoue T. Association between endometriosis and genetic polymorphisms of the estradiol-synthesizing enzyme genes HSD17B1 and CYP19. Human Reprod. 20 4 (2005) 974-978
32. Baker M.E. Unusual evolution of 11beta- and 17beta-hydroxysteroid and retinol dehydrogenases. Bioessays 18 1 (1996) 63-70
33. Baker M.E. Evolution of 17beta-hydroxysteroid dehydrogenases and their role in androgen, estrogen and retinoid action. Mol. Cell. Endocrinol. 171 1/2 (2001) 211-215
34. Breitling R., Laubner D., and Adamski J. Structure-based phylogenetic analysis of short-chain alcohol dehydrogenases and reclassification of the 17beta-hydroxysteroid dehydrogenase family. Mol. Biol. Evol. 18 12 (2001) 2154-2161
35. Napoli J.L. 17Beta-Hydroxysteroid dehydrogenase type 9 and other short-chain dehydrogenases/reductases that catalyze retinoid, 17beta- and 3alpha-hydroxysteroid metabolism. Mol. Cell. Endocrinol. 171 1/2 (2001) 103-109
36. Napoli J.L. Interactions of retinoid binding proteins and enzymes in retinoid metabolism. Biochim. Biophys. Acta 1440 2/3 (1999) 139-162