A concerted, rational design of type 1 17beta-hydroxysteroid dehydrogenase inhibitors: estradiol-adenosine hybrids with high affinity.

The FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Volumn 16, Issue 13, 2002, Pages 1829-1831

  Qiu, Wei ^a   Campbell, Robert L ^a   Gangloff, Anne ^a   Dupuis, Philippe ^a   Boivin, Roch P ^a   Tremblay, Martin R ^a   Poirier, Donald ^a   Lin, Sheng Xiang ^a  

^a UNIVERSITÉ LAVAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

3 (OR 17) BETA HYDROXYSTEROID DEHYDROGENASE; 3 (OR 17)-BETA-HYDROXYSTEROID DEHYDROGENASE; ADENOSINE; ENZYME INHIBITOR; ESTRADIOL; HYDROXYSTEROID DEHYDROGENASE;

ARTICLE; BINDING COMPETITION; CHEMICAL STRUCTURE; CHEMISTRY; DRUG ANTAGONISM; DRUG DESIGN; KINETICS; METABOLISM; PROTEIN CONFORMATION; X RAY CRYSTALLOGRAPHY;

17-HYDROXYSTEROID DEHYDROGENASES; ADENOSINE; BINDING, COMPETITIVE; CRYSTALLOGRAPHY, X-RAY; DRUG DESIGN; ENZYME INHIBITORS; ESTRADIOL; KINETICS; MODELS, MOLECULAR; PROTEIN CONFORMATION;

EID: 0036831679     PISSN: None     EISSN: 15306860     Source Type: Journal    
DOI: None     Document Type: Article

References (0)