17beta-hydroxysteroid dehydrogenase type 1 modulates breast cancer protein profile and impacts cell migration

Breast Cancer Research

Volumn 14, Issue 3, 2012, Pages

  Aka, Juliette A ^a   Zerradi, Mouna ^a   Houle, François ^b   Huot, Jacques ^b   Lin, Sheng Xiang ^a  

^a LAVAL UNIVERSITY   (Canada)

^b University Laval   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

3(OR 17)BETA HYDROXYSTEROID DEHYDROGENASE; ANDROGEN RECEPTOR; BRCA2 PROTEIN; CYCLIN DEPENDENT KINASE INHIBITOR 1A; CYCLINE; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; MESSENGER RNA; NUCLEOSIDE DIPHOSPHATE KINASE A; PROTEOME; BCCIP PROTEIN, HUMAN; BRCA2 PROTEIN, HUMAN; CALCIUM BINDING PROTEIN; CELL CYCLE PROTEIN; ESTRADIOL 17BETA DEHYDROGENASE; HSD17B1 PROTEIN, HUMAN; NME1 PROTEIN, HUMAN; NUCLEAR PROTEIN; NUCLEOSIDE DIPHOSPHATE KINASE NM23; SMALL INTERFERING RNA;

ARTICLE; BREAST CANCER; CANCER CELL; CANCER GROWTH; CELL MIGRATION; CONTROLLED STUDY; CORRELATION ANALYSIS; GENE CONTROL; GENE EXPRESSION; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; GROWTH REGULATION; HUMAN; HUMAN CELL; MASS SPECTROMETRY; PROTEIN EXPRESSION; PROTEOMICS; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; RECEPTOR DOWN REGULATION; RECEPTOR UPREGULATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR SUPPRESSOR GENE; TWO DIMENSIONAL GEL ELECTROPHORESIS; WILD TYPE; WOUND HEALING; BREAST TUMOR; CELL MOTION; CELL PROLIFERATION; CELL STRAIN MCF 7; FEMALE; GENETICS; METABOLISM; PROTEIN MICROARRAY; RNA INTERFERENCE; TUMOR CELL LINE;

BRCA2 PROTEIN; BREAST NEOPLASMS; CALCIUM-BINDING PROTEINS; CELL CYCLE PROTEINS; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; ESTRADIOL DEHYDROGENASES; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; FEMALE; HUMANS; MCF-7 CELLS; NM23 NUCLEOSIDE DIPHOSPHATE KINASES; NUCLEAR PROTEINS; PROLIFERATING CELL NUCLEAR ANTIGEN; PROTEIN ARRAY ANALYSIS; PROTEOME; RECEPTORS, ANDROGEN; RNA INTERFERENCE; RNA, MESSENGER; RNA, SMALL INTERFERING;

EID: 84861993200     PISSN: 14655411     EISSN: 1465542X     Source Type: Journal    
DOI: 10.1186/bcr3207     Document Type: Article

References (40)

1. Sasco AJ. Breast Cancer and the Environment. Horm Res 2003, 60(Suppl 3):50.
2. ESHRE Capri Workshop Group Hormones and breast cancer. Hum Reprod Update 2004, 10:281-293. ESHRE Capri Workshop Group.
3. Jemal A, Siegel R, Ward E, Hao Y, Xu J, Murray T, Thun MJ. Cancer statistics, 2008. CA Cancer J Clin 2008, 58:71-96. 10.3322/CA.2007.0010, 18287387.
4. Canadian Cancer Society's Steering Committee Canadian Cancer Statistics 2009. 2009, Toronto: Canadian Cancer Society, Canadian Cancer Society's Steering Committee., http://www.cancer.ca/statistiques
5. American Cancer Society Breast cancer facts & figures 2009-2010. 2009, Atlanta: American Cancer Society, Inc, American Cancer Society., http://www.cancer.org
6. Russo IH, Russo J. Role of hormones in mammary cancer initiation and progression. J Mammary Gland Biol Neoplasia 1998, 3:49-61. 10.1023/A:1018770218022, 10819504.
7. Russo J, Hasan Lareef M, Balogh G, Guo S, Russo IH. Estrogen and its metabolites are carcinogenic agents in human breast epithelial cells. J Steroid Biochem Mol Biol 2003, 87:1-25. 10.1016/S0960-0760(03)00390-X, 14630087.
8. Nguyen BL, Chetrite G, Pasqualini JR. Transformation of estrone and estradiol in hormone-dependent and hormone-independent human breast cancer cells. Effects of the antiestrogen ICI 164,384, danazol, and promegestone (R-5020). Breast Cancer Res Treat 1995, 34:139-146. 10.1007/BF00665786, 7647331.
9. Pasqualini JR. The selective estrogen enzyme modulators in breast cancer: a review. Biochim Biophys Acta 2004, 1654:123-143.
10. Aka JA, Mazumdar M, Lin S-X. Reductive 17beta-hydroxysteroid dehydrogenases in the sulfatase pathway: critical in the cell proliferation of breast cancer. Mol Cell Endocrinol 2009, 301:183-190. 10.1016/j.mce.2008.10.042, 19038308.
11. Aka JA, Mazumdar M, Chen C-Q, Poirier D, Lin S-X. 17β-hydroxysteroid dehydrogenase Type 1 stimulates breast cancer by dihydrotestosterone inactivation in addition to estradiol production. Mol Endocrinol 2010, 24:832-845. 10.1210/me.2009-0468, 20172961.
12. Oduwole OO, Li Y, Isomaa VV, Mäntyniemi A, Pulkka AE, Soini Y, Vihko PT. 17beta-hydroxysteroid dehydrogenase type 1 is an independent prognostic marker in breast cancer. Cancer Res 2004, 64:7604-7609. 10.1158/0008-5472.CAN-04-0446, 15492288.
13. Gunnarsson C, Jerevall PL, Hammar K, Olsson B, Nordenskjöld B, Jansson A, Stål O. Amplification of HSD17B1 has prognostic significance in postmenopausal breast cancer. Breast Cancer Res Treat 2008, 108:35-41. 10.1007/s10549-007-9579-7, 17457667.
14. Meier M, Möller G, Adamski J. Perspectives in understanding the role of human 17beta-hydroxysteroid dehydrogenases in health and disease. Ann N Y Acad Sci 2009, 1155:15-24. 10.1111/j.1749-6632.2009.03702.x, 19250188.
15. Laplante Y, Rancourt C, Poirier D. Relative involvement of three 17beta-hydroxysteroid dehydrogenases (types 1, 7 and 12) in the formation of estradiol in various breast cancer cell lines using selective inhibitors. Mol Cell Endocrinol 2009, 301:146-153. 10.1016/j.mce.2008.08.026, 18812208.
16. Shevchenko A, Wilm M, Vorm O, Mann M. Mass spectrometric sequencing of proteins from silver-stained polyacrylamide gels. Analytical Chemistry 1996, 68:850-858. 10.1021/ac950914h, 8779443.
17. Havlis J, Thomas H, Sebela M, Shevchenko A. Fast-Response Proteomics by Accelerated In-Gel Digestion of Proteins. Anal Chem 2003, 75:1300-1306. 10.1021/ac026136s, 12659189.
18. Luu-The V, Paquet N, Calvo E, Cumps J. Improved real-time RT-PCR method for high-throughput measurements using second derivative calculation and double correction. Biotechniques 2005, 38:287-293. 10.2144/05382RR05, 15727135.
19. UniProt database. , http://www.uniprot.org
20. Huber M, Bahr I, Krätzschmar J R, Becker A, Müller E C, et al. Comparison of Proteomic and Genomic Analyses of the Human Breast Cancer Cell Line T47D and the Antiestrogen-resistant Derivative T47D-r. Mo Cell Proteomics 2004, 3:43-55.
21. Gygi SP, Rochon Y, Franza BR, Aebersold R. Correlation between Protein and mRNA Abundance in Yeast. Mol Cell Biol 1999, 19:1720-1730. 83965, 10022859.
22. Aka JA, Lin S-X. Comparison of functional proteomic analyses of human breast cancer cell lines T47D and MCF7. PLoS ONE 2012, 7(2):e31532. 10.1371/journal.pone.0031532, 3286449, 22384035.
23. Kim J, Petz LN, Ziegler YS, Wood JR, Potthoff SJ, Nardulli AM. Regulation of the estrogen-responsive pS2 gene in MCF-7 human breast cancer cells. J Steroid Biochem Mol Biol 2000, 74:157-168. 10.1016/S0960-0760(00)00119-9, 11162921.
24. Marchiori AC, Casolari DA, Nagai MA. Transcriptional up-regulation of PHLDA1 by 17beta-estradiol in MCF-7 breast cancer cells. Braz J Med Biol Res 2008, 41:579-582. 10.1590/S0100-879X2008005000029, 18641796.
25. Hevir N, Trošt N, Debeljak N, Rižner TL. Expression of estrogen and progesterone receptors and estrogen metabolizing enzymes in different breast cancer cell lines. Chem Biol Interact 2011, 191:206-216. 10.1016/j.cbi.2010.12.013, 21182832.
26. Smuc T, Rizner TL. Expression of 17beta-hydroxysteroid dehydrogenases and other estrogen-metabolizing enzymes in different cancer cell lines. Chem Biol Interact 2009, 178:228-33. 10.1016/j.cbi.2008.10.038, 19022235.
27. Curtis CD, Likhite VS, McLeod IX, Yates JR, Nardulli AM. Interaction of the tumor metastasis suppressor nonmetastatic protein 23 homologue H1 and estrogen receptor alpha alters estrogen-responsive gene expression. Cancer Res 2007, 67:10600-10607. 10.1158/0008-5472.CAN-07-0055, 17975005.
28. Charpentier AH, Bednarek AK, Daniel RL, Hawkins KA, Laflin KJ, Gaddis S, MacLeod MC, Aldaz CM. Effects of estrogen on global gene expression: identification of novel targets of estrogen action. Cancer Res 2000, 60:5977-5983.
29. Lin KH, Wang WJ, Wu YH, Cheng SY. Activation of Antimetastatic Nm23-H1 Gene Expression by Estrogen and Its alpha-Receptor. Endocrinology 2002, 143:467-475. 10.1210/en.143.2.467, 11796500.
30. Wang DY, Fulthorpe R, Liss SN, Edwards EA. Identification of estrogen-responsive genes by complementary deoxyribonucleic acid microarray and characterization of a novel early estrogen-induced gene: EEIG1. Mol Endocrinol 2004, 18:402-411.
31. Liaudet-Coopman E, Beaujouin M, Derocq D, Garcia M, Glondu-Lassis M, Laurent-Matha V, Prébois C, Rochefort H, Vignon F. Cathepsin D: newly discovered functions of a long-standing aspartic protease in cancer and apoptosis. Cancer Lett 2006, 237:167-179. 10.1016/j.canlet.2005.06.007, 16046058.
32. Flørenes VA, Aamdal S, Myklebost O, Maelandsmo GM, Bruland OS, Fodstad O. Levels of nm23 messenger RNA in metastatic malignant melanomas: inverse correlation to disease progression. Cancer Res 1992, 52:6088-6091.
33. Youn B, Kim HD, Kim J. Nm23-H1/nucleoside diphosphate kinase as a key molecule in breast tumor angiogenesis. Expert Opin Ther Targets 2008, 12:1419-30. 10.1517/14728222.12.11.1419, 18851697.
34. Boissan M, De Wever O, Lizarraga F, Wendum D, Poincloux R, Chignard N, Desbois-Mouthon C, Dufour S, Nawrocki-Raby B, Birembaut P, Bracke M, Chavrier P, Gespach C, Lacombe ML. Implication of metastasis suppressor NM23-H1 in maintaining adherens junctions and limiting the invasive potential of human cancer cells. Cancer Res 2010, 70:7710-7722. 10.1158/0008-5472.CAN-10-1887, 20841469.
35. Miyoshi Y, Ando A, Hasegawa S, Ishitobi M, Tamaki Y, Noguchi S. High expression of steroid sulfatase mRNA predicts poor prognosis in patients with estrogen receptor-positive breast cancer. Clin Cancer Res 2003, 9:2288-2293.
36. Irahara N, Miyoshi Y, Taguchi T, Tamaki Y, Noguchi S. Quantitative analysis of aromatase, sulfatase and 17beta-HSD(1) mRNA expression in soft tissue metastases of breast cancer. Cancer Lett 2006, 243:23-31. 10.1016/j.canlet.2005.11.010, 16556483.
37. Salhab M, Reed MJ, Al Sarakbi W, Jiang WG, Mokbel K. The role of aromatase and 17-beta-hydroxysteroid dehydrogenase type 1 mRNA expression in predicting the clinical outcome of human breast cancer. Breast Cancer Res Treat 2006, 99:155-162. 10.1007/s10549-006-9198-8, 16541304.
38. Mindnich R, Adamski J. Zebrafish 17beta-hydroxysteroid dehydrogenases: an evolutionary perspective. Mol Cell Endocrinol 2009, 301:20-26. 10.1016/j.mce.2008.12.002, 19111899.
39. Poirier D, Mazumdar M, Lin S-X. Design and synthesis of bisubstrate inhibitors of type 1 17β-hydroxysteroid dehydrogenase: Overview and perspectives. Eur J Med Chem 2008, 43:2298-2306. 10.1016/j.ejmech.2008.01.044, 18372081.
40. Zhang C-Y, Chen J, Yin D-C, Lin S-X. The contribution of 17beta-hydsroxysteroid dehydrogenase type 1 to estrtadiol-estrone ration in breast cancer cells. PLoS ONE 2012, 7(1):e29835. 10.1371/journal.pone.0029835, 3253791, 22253796.