17β-hydroxysteroid dehydrogenase type 1 stimulates breast cancer by dihydrotestosterone inactivation in addition to estradiol production

Molecular Endocrinology

Volumn 24, Issue 4, 2010, Pages 832-845

  Aka, Juliette A ^a   Mazumdar, Mausumi ^a   Chen, Chang Qing ^a   Poirier, Donald ^a   Lin, Sheng Xiang ^a  

^a LAVAL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

17BETA HYDROXYSTEROID DEHYDROGENASE TYPE 1; ANDROSTANOLONE; ESTRADIOL; ESTROGEN; ESTRONE; PROTEIN PS2; TESTOSTERONE 17BETA DEHYDROGENASE; UNCLASSIFIED DRUG; ESTRADIOL 17BETA DEHYDROGENASE; HSD17B1 PROTEIN, HUMAN; SMALL INTERFERING RNA;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BINDING AFFINITY; BREAST CANCER; CANCER CELL; CANCER CELL CULTURE; CATABOLISM; CELL GROWTH; CELL PROLIFERATION; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG INHIBITION; ESTROGEN ACTIVITY; ESTROGEN RESPONSIVE ELEMENT; ESTROGEN SYNTHESIS; GENE EXPRESSION; GENE INACTIVATION; GROWTH INHIBITION; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RECEPTOR UPREGULATION; REDUCTION; RNA INTERFERENCE; BREAST TUMOR; CELL LINE; GENETICS; MASS FRAGMENTOGRAPHY; METABOLISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR CELL LINE; WESTERN BLOTTING;

BLOTTING, WESTERN; BREAST NEOPLASMS; CELL LINE; CELL LINE, TUMOR; CELL PROLIFERATION; DIHYDROTESTOSTERONE; ESTRADIOL; ESTRADIOL DEHYDROGENASES; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HUMANS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, SMALL INTERFERING;

EID: 77950421854     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/me.2009-0468     Document Type: Article

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