Discovery of novel melanacortin4 receptor selective MSH analogues

British Journal of Pharmacology

Volumn 124, Issue 1, 1998, Pages 75-82

  Schiöth, Helgi B ^a,c   Mutulis, Felikss ^a,b   Muceniece, Ruta ^a,b   Prusis, Peteris ^a   Wikberg, Jarl E S ^a,c  

^a UPPSALA UNIVERSITY   (Sweden)

^b LATVIAN INSTITUTE OF ORGANIC SYNTHESIS   (Latvia)

^c UPPSALA UNIVERSITY   (Sweden)

Author keywords

Cyclic AMP; Cyclic MSH analogues; HS014; HS964; Ligand binding; Melanocortin (MC) receptor subtypes; MSH (melanocyte stimulating hormone)

Indexed keywords

BETA INTERMEDIN[11-22][11 (N ACETYLCYSTEINE) 14 [3 (2 NAPHTHYL) DEXTRO ALANINE] 18 CYSTEINE 22 ASPARTIC ACID AMIDE] 11,18 CYCLIC DISULFIDE; CYCLIC AMP; HS 9510; HS 964; MELANOCORTIN; MELANOCORTIN DERIVATIVE; MELANOCORTIN RECEPTOR; N ACETYL ALPHA INTERMEDIN[4-10]CYCLO[4 NORLEUCINE 5 ASPARTIC ACID 7 [3 (2 NAPHTHYL)ALANINE] 10 LYSINAMIDE]; RECEPTOR SUBTYPE; UNCLASSIFIED DRUG; CORTICOTROPIN RECEPTOR; INTERMEDIN; MELANOCORTIN 4 RECEPTOR; RECOMBINANT PROTEIN;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CHEMICAL STRUCTURE; CONTROLLED STUDY; DRUG POTENCY; GENETIC TRANSFECTION; NONHUMAN; PRIORITY JOURNAL; RECEPTOR AFFINITY; RECEPTOR BINDING; STRUCTURE ACTIVITY RELATION; AMINO ACID SEQUENCE; ANIMAL; CELL CULTURE; CELL STRAIN COS1; CHEMISTRY; DRUG DESIGN; EXPERIMENTAL MELANOMA; HUMAN; METABOLISM; MOUSE; PATHOLOGY;

AMINO ACID SEQUENCE; ANIMALS; COS CELLS; CYCLIC AMP; DRUG DESIGN; HUMANS; MELANOCYTE-STIMULATING HORMONES; MELANOMA, EXPERIMENTAL; MICE; RECEPTOR, MELANOCORTIN, TYPE 4; RECEPTORS, CORTICOTROPIN; RECOMBINANT PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR CELLS, CULTURED;

EID: 0031596459     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0701804     Document Type: Article

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