Bradycardia alters Ca2+ dynamics enhancing dispersion of repolarization and arrhythmia risk

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 304, Issue 6, 2013, Pages

  Kim, Jong J ^a,b   Němec, Jan ^b   Papp, Rita ^b   Strongin, Robert ^c   Abramson, Jonathan J ^c   Salama, Guy ^a,b  

^a University of Pittsburgh   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^c PORTLAND STATE UNIVERSITY   (United States)

Author keywords

Action potential adaptation; Arrhythmia; Bradycardia; Optical mapping; Secondary Ca2+ release

Indexed keywords

CALCIUM RELEASE ACTIVATED CALCIUM CHANNEL; RYANODINE RECEPTOR;

ACTION POTENTIAL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRADYCARDIA; CALCIUM SIGNALING; CARDIOVASCULAR RISK; ELECTROCARDIOGRAM; FEMALE; HEART ARRHYTHMIA; HEART RATE; HEART REPOLARIZATION; ISOLATED HEART; NONHUMAN; PRIORITY JOURNAL; QT DISPERSION; RABBIT; SARCOPLASMIC RETICULUM; WESTERN BLOTTING;

ACTION POTENTIALS; ANIMALS; BRADYCARDIA; CALCIUM CHANNELS, L-TYPE; CALCIUM SIGNALING; ETHER-A-GO-GO POTASSIUM CHANNELS; FEMALE; GENE EXPRESSION REGULATION; HEART RATE; MYOCARDIAL REPERFUSION; NAV1.5 VOLTAGE-GATED SODIUM CHANNEL; PLASMA MEMBRANE CALCIUM-TRANSPORTING ATPASES; RABBITS; RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL; SARCOPLASMIC RETICULUM; SODIUM-CALCIUM EXCHANGER; TACHYCARDIA; THIAZEPINES;

EID: 84878544584     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00787.2012     Document Type: Article

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