Regional genomic regulation of cardiac sodium-calcium exchanger by oestrogen

Journal of Physiology

Volumn 589, Issue 5, 2011, Pages 1061-1080

  Chen, Guojun ^a   Yang, Xiaoyan ^a   Alber, Sean ^b   Shusterman, Vladimir ^a   Salama, Guy ^a  

^a DMC Cardiovascular Institute   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; DACTINOMYCIN; DOFETILIDE; ESTRADIOL; ESTROGEN RECEPTOR; FULVESTRANT; MESSENGER RNA; SODIUM CALCIUM EXCHANGE PROTEIN; UNCLASSIFIED DRUG; VOLTAGE GATED CALCIUM CHANNEL; VOLTAGE GATED CALCIUM CHANNEL CAV1.2ALPHA;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CALCIUM CURRENT; CALCIUM HOMEOSTASIS; CALCIUM TRANSPORT; CELL CULTURE; CONTROLLED STUDY; CULTURE MEDIUM; EPICARDIUM; FEMALE; GENE CONTROL; GENOMICS; HEART DEPOLARIZATION; HEART FUNCTION; HEART LEFT VENTRICLE CONTRACTION; HEART MUSCLE CELL; INCUBATION TIME; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; RABBIT; SEX DIFFERENCE; TRANSCRIPTION REGULATION; TRANSLATION REGULATION; UPREGULATION; VOLTAGE CLAMP;

ANIMALS; BLOTTING, WESTERN; CYCLOHEXIMIDE; DACTINOMYCIN; ELECTROPHYSIOLOGY; ESTRADIOL; ESTROGEN ANTAGONISTS; ESTROGENS; FEMALE; HEART; IMMUNOHISTOCHEMISTRY; MALE; MYOCARDIUM; MYOCYTES, CARDIAC; PHENETHYLAMINES; PROTEIN SYNTHESIS INHIBITORS; RABBITS; SODIUM-CALCIUM EXCHANGER; SULFONAMIDES;

EID: 79951977055     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/jphysiol.2010.203398     Document Type: Article

References (54)

1. Abi-Gerges N, Philp K, Pollard C, Wakefield I, Hammond TG & Valentin JP (2004). Sex differences in ventricular repolarization: from cardiac electrophysiology to Torsades de Pointes. Fundam Clin Pharmacol 18, 139-151.
2. 2+ exchange inhibitor. Cardiovasc Drug Rev 21, 255-276.
3. Armoundas AA, Hobai IA, Tomaselli GF, Winslow RL & O'Rourke B (2003). Role of sodium-calcium exchanger in modulating the action potential of ventricular myocytes from normal and failing hearts. Circ Res 93, 46-53.
4. 2+ exchange inhibitor 2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate (KB-R7943) also blocks ryanodine receptors type 1 (RyR1) and type 2 (RyR2) channels. Mol Pharmacol 76, 560-568.
5. Bednar MM, Harrigan EP & Ruskin JN (2002). Torsades de pointes associated with nonantiarrhythmic drugs and observations on gender and QTc. Am J Cardiol 89, 1316-1319.
6. 2+ current in adult rat cardiomyocytes. Circ Res 85, 1139-1145.
7. Berger M, Jean-Faucher C, de Turckheim M, Veyssiere G, Blanc MR, Poirier JC & Jean C (1982). Testosterone, luteinizing hormone (LH) and follicle stimulating hormone (FSH) in plasma of rabbit from birth to adulthood. Correlation with sexual and behavioural development. Acta Endocrinol (Copenh) 99, 459-465.
8. Bers DM (2007). Calcium cycling and signaling in cardiac myocytes. Annu Rev Physiol 70, 23-49.
9. + current: a potential mechanism of the proarrhythmic effects of methanesulfonanilideclass III agents. Cardiovasc Res 43, 135-147.
10. 2+ triggers early afterdepolarizations and Torsade de Pointes in rabbit hearts with type 2 long QT syndrome. J Physiol 543, 615-631.
11. Chu SH, Goldspink P, Kowalski J, Beck J & Schwertz DW (2006). Effect of estrogen on calcium-handling proteins, β-adrenergic receptors, and function in rat heart. Life Sci 79, 1257-1267.
12. Chu SH, Sutherland K, Beck J, Kowalski J, Goldspink P & Schwertz D (2005). Sex differences in expression of calcium-handling proteins and β-adrenergic receptors in rat heart ventricle. Life Sci 76, 2735-2749.
13. Coker SJ (2008). Drugs for men and women - How important is gender as a risk factor for TdP? Pharmacol Ther 119, 186-194.
14. de Turckheim M, Berger M, Jean-Faucher C, Veyssiere G & Jean C (1983). Changes in ovarian oestrogens and in plasma gonadotrophins in female rabbits from birth to adulthood. Acta Endocrinol (Copenh) 103, 125-130.
15. Drummond GB (2009). Reporting ethical matters in The Journal of Physiology: standards and advice. J Physiol 587, 713-719.
16. Goldenberg I, Moss AJ, Peterson DR, McNitt S, Zareba W, Andrews ML, Robinson JL, Locati EH, Ackerman MJ, Benhorin J, Kaufman ES, Napolitano C, Priori SG, Qi M, Schwartz PJ, Towbin JA, Vincent GM & Zhang L (2008). Risk factors for aborted cardiac arrest and sudden cardiac death in children with the congenital long-QT syndrome. Circulation 117, 2184-2191.
17. Hara M, Danilo P Jr & Rosen MR (1998). Effects of gonadal steroids on ventricular repolarization and on the response to E4031. J Pharmacol Exp Ther 285, 1068-1072.
18. Hobai IA, Maack C & O'Rourke B (2004). Partial inhibition of sodium/calcium exchange restores cellular calcium handling in canine heart failure. Circ Res 95, 292-299.
19. 2+ exchange activity in canine pacing-induced heart failure. Circ Res 87, 690-698.
20. 2+ exchange in cells expressing NCX1. J Biol Chem 271, 22391-22397.
21. 2+ current. Circ Res 64, 977-990.
22. Kieval RS, Bloch RJ, Lindenmayer GE, Ambesi A & Lederer WJ (1992). Immunofluorescence localization of the Na-Ca exchanger in heart cells. Am J Physiol Cell Physiol 263, C545-550.
23. 2+ exchange current by KB-R7943 in guinea-pig cardiac myocytes. Br J Pharmacol 128, 969-974.
24. 2+ exchange inhibitor KB-R7943 potently blocks TRPC channels. Biochem Biophys Res Commun 361, 230-236.
25. 2+ exchange in the heart from ovariectomized rats: role of protein kinase A. Am J Physiol Cell Physiol 292, C1625-1635.
26. Levin ER (2002). Estrogen receptor-β and the cardiovascular system. Trends Endocrinol Metab 13, 184-185.
27. Levin ER (2008). Rapid signaling by steroid receptors. Am J Physiol Regul Integr Comp Physiol 295, R1425-1430.
28. Liu T, Choi BR, Drici MD & Salama G (2005). Sex modulates the arrhythmogenic substrate in prepubertal rabbit hearts with Long QT 2. J Cardiovasc Electrophysiol 16, 516-524.
29. Maack C, Ganesan A, Sidor A & O'Rourke B (2005). Cardiac sodium-calcium exchanger is regulated by allosteric calcium and exchanger inhibitory peptide at distinct sites. Circ Res 96, 91-99.
30. Makkar RR, Fromm BS, Steinman RT, Meissner MD & Lehmann MH (1993). Female gender as a risk factor for torsades de pointes associated with cardiovascular drugs. JAMA 270, 2590-2597.
31. Marban E, Robinson SW & Wier WG (1986). Mechanisms of arrhythmogenic delayed and early afterdepolarizations in ferret ventricular muscle. J Clin Invest 78, 1185-1192.
32. Mitcheson JS, Hancox JC & Levi AJ (1996). Action potentials, ion channel currents and transverse tubule density in adult rabbit ventricular myocytes maintained for 6 days in cell culture. Pflugers Arch 431, 814-827.
33. Mitcheson JS, Hancox JC & Levi AJ (1997). Cultured adult rabbit myocytes: effect of adding supplements to the medium, and response to isoprenaline. J Cardiovasc Electrophysiol 8, 1020-1030.
34. Mitcheson JS, Hancox JC & Levi AJ (1998). Cultured adult cardiac myocytes: future applications, culture methods, morphological and electrophysiological properties. Cardiovasc Res 39, 280-300.
35. Nagy ZA, Virag L, Toth A, Biliczki P, Acsai K, Banyasz T, Nanasi P, Papp JG & Varro A (2004). Selective inhibition of sodium-calcium exchanger by SEA-0400 decreases early and delayed after depolarization in canine heart. Br J Pharmacol 143, 827-831.
36. Osborne CK, Wakeling A & Nicholson RI (2004). Fulvestrant: an oestrogen receptor antagonist with a novel mechanism of action. Br J Cancer 90(Suppl 1), S2-S6.
37. 2+ load attributable to the predominance of forward mode block. Circ Res 102, 1398-1405.
38. K-blocking drugs. Circulation 103, 2207-2212.
39. Pogwizd SM, Schlotthauer K, Li L, Yuan W & Bers DM (2001). Arrhythmogenesis and contractile dysfunction in heart failure: Roles of sodium-calcium exchange, inward rectifier potassium current, and residual β-adrenergic responsiveness. Circ Res 88, 1159-1167.
40. Robertson JF (2001). ICI 182, 780 (Fulvestrant)-the first oestrogen receptor down-regulator - current clinical data. Br J Cancer 85(Suppl 2), 11-14.
41. Roden DM (2004). Drug-induced prolongation of the QT interval. N Engl J Med 350, 1013-1022.
42. Roden DM (2008). Clinical practice. Long-QT syndrome. N Engl J Med 358, 169-176.
43. Sambrano GR, Fraser I, Han H, Ni Y, O'Connell T, Yan Z & Stull JT (2002). Navigating the signalling network in mouse cardiac myocytes. Nature 420, 712-714.
44. 2+ uniporter. Br J Pharmacol 151, 647-654.
45. 2+ overload in rat ventricular myocytes. Circulation 101, 1441-1446.
46. Schackow TE, Decker RS & Ten Eick RE (1995). Electrophysiology of adult cat cardiac ventricular myocytes: changes during primary culture. Am J Physiol Cell Physiol 268, C1002-1017.
47. 2+ exchanger in end-stage failing human myocardium. Eur Heart J 23, 1118-1124.
48. Sims C, Reisenweber S, Viswanathan PC, Choi BR, Walker WH & Salama G (2008). Sex, age, and regional differences in L-type calcium current are important determinants of arrhythmia phenotype in rabbit hearts with drug-induced long QT type 2. Circ Res 102, e86-100.
49. + in canine and guinea pig Purkinje fibers. J Cardiovasc Electrophysiol 6, 796-812.
50. Verduyn SC, Vos MA, Gorgels AP, Van Der Zande J, Leunissen JD & Wellens HJ (1995). The effect of flunarizine and ryanodine on acquired torsades de pointes arrhythmias in the intact canine heart. J Cardiovasc Electrophysiol 6, 189-200.
51. Viswanathan PC & Rudy Y (1999). Pause induced early afterdepolarizations in the long QT syndrome: a simulation study. Cardiovasc Res 42, 530-542.
52. Volders PG, Vos MA, Szabo B, Sipido KR, de Groot SH, Gorgels AP, Wellens HJ & Lazzara R (2000). Progress in the understanding of cardiac early afterdepolarizations and torsades de pointes: time to revise current concepts. Cardiovasc Res 46, 376-392.
53. Wei SK, McCurley JM, Hanlon SU & Haigney MC (2007a). Gender differences in Na/Ca exchanger current and β-adrenergic responsiveness in heart failure in pig myocytes. Ann N Y Acad Sci 1099, 183-189.
54. Wei SK, Ruknudin AM, Shou M, McCurley JM, Hanlon SU, Elgin E, Schulze DH & Haigney MC (2007b). Muscarinic modulation of the sodium-calcium exchanger in heart failure. Circulation 115, 1225-1233.